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        韓國人의 肝炎B抗原分布 關한 硏究

        이호왕(李鎬汪),이용주(李容周),이평우(李平佑),백승용(白承龍),이규진(李圭振) 대한바이러스학회 1974 Journal of Bacteriology and Virology Vol.4 No.1

        Acute viral hepatitis remains a rnajor worldwide public health problem. Epide'miologic and laboratory investigations indicate that 2 specific viruses are involved in this disease. The epidemiologic distinctiveness of these 2 viruses has recently been challenged. Viral hepatitis A, transrnitted primarily by the fecal-oral route, is also transmitted by the parenteral route. Viral hepatitis B occurs sporadically following parenteral inoculation of virus-infected blood products, although recent studies have deinonstrated that oral transinission can also occur. Distribution of Hepatitis B antigen (HB Ag) in Korean was investigated and the results are followings. 1. 3.1% out of 7,360 sera from paid blood donors of Korea University Woo-Suk hospital blood bank was HB Ag positive. In early stage of test, it was 5-10% but subsequently decreased gradually and was about 3% at the end of 1974. 2. The distribution of HB Ag in each age groups was investigated. The highest was in 11-20 age group (12. 7%) and 21-40 age group succeeded it. In sexual difference of it, male was twice as high as female in 11-20 age group but the difference was little in other age groups. The positive rate of antibody to HB Ag was the highest in 11-20 age group (2.7%) 3. Of 1,407 sera from out patients of Woo-Suk hospital, the distribution of HB Ag was the highest (9.8%) in the Department Gastrointestinal medicine and next was the Departments Chest surgery (9.5%) and Urology (7.8%) The distribution of hepatitis B antibody was the highest in General surgery (5.2%), Urology (4.7%) and next was Chest internal medicine (1.%) 4. The frequency of HB Ag in hlood donors from three blood banks in Seoul, positiveness was about 7% and out patients were 5.2%.

      • 상호작용 데이터베이스의 웹 서비스 기반 통합

        이호일,유성준,김민경,박선희 한국정보과학회 2004 데이타베이스 연구 Vol.20 No.2

        바이오인포매틱스 연구에서 정보의 통합은 단순히 정보의 양을 늘릴 뿐만 아니라, 서로 다른 유형의 정보를 참조하여 정보의 질을 향상시키고, 궁극적으로는 데이터로부터 의미있는 발견을 도출 가능하게 할 것으로 기대된다. 데이터베이스를 통합하는 기존의 방법들로는 데이터웨어 하우징과 페더레이티드 방식의 접근이 있었다. 하지만 이러한 통합 방법은 특정 시스템에 맞게 데이터베이스를 설계하기 때문에 재활용이 힘들고, 소스 데이터베이스의 빈번한 업데이트와 스키마 변화 때문에 유지관리가 어렵다. 하지만 본 연구에서는 이런 문제점을 해결하기 위해 웹 서비스 기반으로 통합한다. 이 논문에서는 단백질체학의 대두등으로 그 데이터의 양과 중요성이 부각되고 있는 단백질 상호작용 및 패스웨이 데이터베이스인 BIND, DIP,MINT 데이터베이스를 웹 서비스를 이용하여 제공 및 통합하는 것을 기술한다.

      • KCI등재

        우포늪의 홀로세 동안 퇴적환경 변화 및 돌말류 분포 특성

        이호일,이상득,이진영,임재수,권대률,박미례,윤석민 한국하천호수학회 2020 생태와 환경 Vol.53 No.2

        Upo Wetland is the largest riverine wetland in Korea which has been inscribed on the Ramsar List of Wetlands of International Importance in 1998. In this study, sedimentological study was carried out in order to understand the environmental changes in Upo Wetland during the Holocene. The drilling work for recovering the Quaternary sediments was conducted on the inner part (UPW17-01, UPW17-02, and UPW17-03) and the outer part (UPL17-01, UPL17-02) of the Upo Wetland. The recovered sediments are commonly characterized by gravel-dominated deposits in the lower part and silty clay-dominated deposits in the middle to upper parts respectively, which are seemed to be changed from fluvial to palustrine/lacustrine environments around 4,000 cal yr BP. In order to establish the Holocene diatoms distribution from Upo Wetland, we identified 63 diatom taxa. Of these, 14 species were new records for Korea: Gomphonema consector, Gomphonema jadwigiae, Hantzschia abundans, Luticola pseudomurrayi, Luticola spauldingiae, Neidium suboblongum, Ninastrelnikovia gibbosa, Oricymba rhynchocephala, Pinnularia borealis var. lanceolata, Pinnularia latarea, Pinnularia paliobducta, Pinnularia saprophila, Sellaphora laevissima, Stauroneis pseudoschimanskii. All identified diatom species are illustrated by high-quality scanning electron microscopic and light microscopic microphotographs. The ecological habitat for all taxa are presented.

      • Thyroxine과 Methimazole이 흰쥐의 姙娠에 미치는 影響

        李浩一 全北大學校 師範大學 1977 사대논문집 Vol.3 No.-

        In order to investigate the effects of thyroxine and methimazole on female reproductive system, healthy female albino rats were selected at random. The body weights of these animals at around 100 days of age ranged between 145 175 at the beginning of the experiment. The female 18 rats used in this work were alloted to groups of three. Rats in one group were served as control and the other two groups were administered orally thyroxine of 1㎎/100g/day and methimazole of 0.2㎎/100g/day respectively for 4 weeks. Healthy 12 male rats at 4 months of age were put into both cages of three groups from the 16th day after administered for 10 days to let therm cross naturally. The results obtained in this work were summarized as follows : 1. There was not any remarkable difference of increasing body weight among three groups. 2. Also there was not any difference of mean body weight of newborns among three groups. 3. On litter size, there was not any difference between thyroxine and control groups, but there was a decreasing tendency in methimazole group compared with the other two groups.

      • 韓牛, 在來山羊 및 野生노루의 第一胃內에 棲息하는 纖毛蟲類의 分類에 관한 基礎硏究

        李浩一 全北大學校 生物學硏究所 1981 生物學硏究年報 Vol.2 No.-

        In order to classify the rumen ciliates of the ruminants, from 50 Korean cattle slaughtered at Jeonju abattoir from April to June, from 20 native goats slaughtered at civilian private abattoir from February to April and from 3 wild roe deer captured by remote villagers in February, the rumen contents were collected. The results obtained in this work were summarized as follows : 1. The average pH of rumen contents of cattle, goat and roe deer were 6.40, 5.82 and 5.23, respectively. 2. Ten genera 28 species of ciliates from cattle, 4 genera 11 species from goats and a single genus 4 species from roe deer were classified. 3. The appearance rate of Entodinium was the highest as 84.09%, Charon was the lowest as 0.03%, E. simplex was the highest as 68.72% and Epidinium ecaudatum cattaneoi and Charon equi were the lowest as 0.03% in cattle. In goats, the appearance rate of Entodinirum was also the highest as 99.29% as in cattle, Epidinium was the lowest as 0.07%, E. simplex was the highest as 94.01%, and Ep. ecaudatum caudatum species was the lowest as 0.07% And in roe deer, only a single genus Entodinium appearance rate of E. simplex was the highest as 95.00% as in cattle and goats, and E. nanellum was the lowest as 0.60%. 4. Four species, classified in roe deer, E. nanellum, E. longinucleatum, E. vorax and E. simplex were also classified commonly in cattle and goats. 5. One unidentified species of Epidinium had two caudal spines characteristically.

      • KCI등재
      • 細宰의 抗炎作用에 관한 硏究

        李浩一 전북대학교 농업과학기술연구소 1975 農大論文集 Vol.6 No.-

        The essential oil extracted from Asiasari radix was studied for anti-inflammatory activity against the-exudative and proliferative phase of inflammation by formalin filterpaper pellet-induced in Albino rats of either sex weighing between 180 and 250g. Indomethacin and Triamcinolone were used as standard drugs for comparison. The essential oil 0.5ml per 100g body weight daily in concentration of 0.1 and 0.2 % were given interaperitoneally in rats for six days. The granular tissue was weighed on the sixthday and histopathological changes were investigated on the third and sixth day. The results obtained were summarized as follows : 1. After six days of experiment, the weight of granular tissue of control group was 68.25mg, those of 0.1 and 0.2% essential oil were 30.16 and 29. 14mg respectively. The weights of experimental groups showed highly significant decrease, but there was no difference between two experimental groups. 2. Exudate and granular tissue formation around the filterpaper pellets of experimental groups were decreased on the third day, and on the sixth day they were decreased remarkably compared with exudate and granular tissue formation of control group. 3. Leucocytes infiltration-mostly heterophil leucocytes and a few macrophages and Iymphocytes-of control group was notable, and there was similar changes in experimental group on the third day, but on the sixth day changes of experimental group disappeared. 4. The weights of granular tissue of either standard groups were decreased more than that of experimental group. and even exudation, leucocytes infiltration and collagenous fiber of the former were dereased more than that of the latter.

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