국립중앙도서관 귀중서고 내 알데히드류 및 휘발성유기화합물(VOCs)에 대한 건강위해성평가

이혜원,임희빈,이귀복,박소연,전정인,이철민,Lee, Hye-Won,Lim, Hui Been,Lee, Kwi-Bok,Park, So Yeon,Jeon, Jeong In,Lee, Cheol Min 한국환경과학회 2020 한국환경과학회지 Vol.29 No.6

This study investigates the concentration distribution of aldehydes and volatile organic compounds (VOCs) in the archive of the National Library in Korea and evaluates the health risks to workers from hazardous chemicals. Acetaldehyde had the highest concentration among the nine species of aldehydes present in the archive and the concentration of toluene was the highest among the six species of VOCs. Most of the detected substances showed that their indoor concentrations were higher than the outdoor ones, suggesting the possibility of indoor sources of aldehydes and VOCs. The evaluation of health risks for workers based on these measurement results showed that not all substances were hazardous to the human body. However, considering the possibility of the presence of indoor sources and the potential limits of our study owing its short period, it is necessary to conduct long-term studies on the concentration distribution of indoor pollutants in the archive environment.

가토 간내 선택적 담관결찰후 간부피의 변화에 대한 실험적 연구

이혜원,윤엽,고영태,최우석,임주원,오주형,임형택,김윤화,이석환,Lee, Hye Won,Yoon, Yup,Ko, Young Tae,Choi, Woo Suk,Lim, Joo Won,Oh, Joo Hyeong,Rim, Heyong Teck,Kim, Youn Wha,Lee, Seok Hwan 대한영상의학회 1998 대한영상의학회지 Vol.39 No.6

Purpose : To evaluate the role of bile duct obstuction in the development of atrophy of the liver, using ananimal model. Materials and Methods : Seven rabbits were divided into two groups : group 1(n=5), in which therewas selective bile duct ligation, and group 2(n=2), which underwent a sham operation. Each group was evaluatedusing CT for changes in hepatic volume after selective bile duct ligation or a sham operation. In group I, thediameter of dilated bile duct was measured 2, 4, 8, 12 and 16 weeks after bile duct ligation, while gross andhistologic change were evaluated in all cases. Results : In group 1, bile duct dilatation was seen on CT two weeksafter selective bile duct ligation, and did not change significantly during follow-up. In four of five cases, CTrevealed no evidence of significant atrophy of the involved segment. Pathologic specimens, however, revealeddilatation of the bile duct, periductal fibrosis, infiltration of chronic inflammatory cells, and periportalfibrosis. One of five cases showed segmental liver atrophy after selective bile duct ligation. In addion to theabove pathologic findings, there was obstruction of the portal vein by foreign body reaction. In group 2, noevidence of dilated bile duct or liver atrophy was revealed by CT or pathologic specimen after a sham operation.Conclusion : During long-term follow-up of 16 weeks, obstruction of the bile duct did not play a major role in thedevelopment of lobar atrophy in the rabbit.

서울국제도서전 결산과 과제

이혜원,Lee, Hye-Won 대한출판문화협회 2004 출판저널 Vol.344 No.-

이벤트 - 2005서울국제도서전

이혜원,Lee, Hye-Won 대한출판문화협회 2005 출판저널 Vol.356 No.-

음양곽으로부터 Icariin의 분리 및 함량분석

이혜원,황성원,고병섭,김호경,Lee, Hye-Won,Hwang, Seong-Won,Ko, Byoung-Seob,Kim, Ho-Kyoung 한국생약학회 2001 생약학회지 Vol.32 No.1

Epimedii Herba has been used for tonic, cardiotonic, impotency, amnestic and diuretic. Icariin, a main component was isolated from the Epimedii Herba and identified by the spectroscopic methods. In order to evaluate the quality of Epimedii Herba purchased from various regions of Korea, quantitative determination of icariin in Epimedii Herba using HPLC method has been conducted. Quantitative analysis showed the average amount of icariin in commercial 42 samples was 0.34% on the dry weight basis.

Nut류의 항산화 및 항균효과

이혜원,최무영,차배천,Lee, Hye-Won,Choi, Moo-Young,Cha, Bae-Cheon 한국생약학회 1998 생약학회지 Vol.29 No.1

It has been known that diseases related with aging or cancer result, at least in part, from free radicals, and antioxidants may reduce or prevent the abnormalities associated with free radical formation via its scavenging action. Thus, this study was carried out to investigate the antioxidative and antimicrobial activities of nut species for the purpose of developing antioxidant from natural products. Antioxidant activities of four kinds of nuts such as chestnut, groundnut, walnut and acorn were examined by measuring the radical scavenging effect on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical. The extracts from chestnut hull and acorn barnyard millet showed strong antioxidative activities among 10 samples tested. Because of their highest antioxidative activity among 10 samples, radical scavenging effects of 4 different extract compartments (Hexane, EtOAc, BuOH and $H_2O$ extracts) from chestnut hull and acorn barnyard millet, were further examined by DPPH method. EtOAc and BuOH extracts exhibited antioxidative activities similar to those of natural, tocopherol or synthetic antioxidants, BHA. These findings demonstrates that major fraction of the antioxidative activity of chestnut hull or acorn barnyard millet was the EtOAc and BuOH extract compartments. However, antimicrobial activities against food-related bacteria and yeasts was relatively weak.

TPCK 프레임워크를 기반으로 한 교과교사와 사서교사 간의 교수-학습 협력에 관한 연구

이혜원,Lee, Hye-Won 한국도서관정보학회 2008 한국도서관정보학회지 Vol.39 No.2

본 연구에서는 정보활용능력을 향상시키기 위해 학교도서관의 사서교사와 일반 교과의 교사들 간의 협력 방안을 제시하고자 하였다. 또한 교육의 또 다른 주체인 학생을 중심으로 한 부분을 확대함으로써 좀 더 효율적인 교수-학습이 이루어질 수 있도록 하였다. 무엇보다 교사와 학생들의 커뮤니케이션에서 직접적인 교환이 이루어지는 지식을 중심으로 주제, 교육학적인 배경, 정보기술의 활용 등을 고려한 모형을 제안하였다. In this study, collaboration of teacher librarians and subject teachers in school libraries has been investigated(tried, attempted, suggested) in order to improve the information literacy. The effective teaching-learning can be conducted by extending student's roles, which are essential elements in school education. Above all, the model. focused on direct exchange of knowledges in communications between teachers and students has been suggested with consideration of content knowledge, pedagogical knowledge, and technological knowledge.

역사용어 온톨로지 모형 적용 방안 연구 - 한국근현대사 인물을 중심으로 -

이혜원,윤소영,Lee, Hye-Won,Yoon, So-Young 한국비블리아학회 2011 한국비블리아학회지 Vol.22 No.1

본 연구에서는 역사인물 중심의 온톨로지를 구축하기 위해 기존의 한국역사용어시소러스의 문제점을 분석하는 동시에 한국역사용어시소러스 및 국편의 다양한 정보검색 시스템을 활용하는 전문가들의 인터뷰를 실시하였다. 한국역사용어시소러스의 개념 표현 기준과 전문가들이 작성한 마인드맵을 분석하여 현재 시스템과 전문가간의 정보 표현의 차이를 확인하였다. 이를 바탕으로 역사정보 이용자들의 정보요구에 부합하고 잠재력 있는 정보검색시스템에 적용할 역사용어 온톨로지 모형을 설계하였다. 본 연구에서는 먼저 클래스, 속성을 정의하고, 인스턴스 입력시 고려해야 할 점들을 나열함으로써, 역사정보가 갖는 고유한 특성들을 정리하였다. 또한 온톨로지의 장점인 개념 확장을 활용하여 역사정보의 다양한 특성들을 조합하고 이를 통해 새로운 정보를 제공할 수 있는 가능성을 제시하였다. The purpose of the study is to construct a History Ontology Model for historical person to analyse issues of Korean History Thesaurus and interview history specialists who are use information systems in National Institute of Korean History. This study verifies the difference between both descriptions through comparative analysis of term concept in Korean History Thesaurus and mind-map written by history major. Based on this, we build history ontology model to meet users' information needs and adapt to information retrieval system. First, to organize unique features of history, we define class and attribute and then enlisted considerations for instance input. The study suggests a possibility of new service through combination multiple features using concept extension that is a strength of ontology.

온톨로지 구조로 표현된 FRSAD 모형에 관한 연구

이혜원,Lee, Hye-Won 한국비블리아학회 2012 한국비블리아학회지 Vol.23 No.1

FRSAD과 온톨로지 모형간의 연계는 어떠한 정보구현시스템이나 특정 상황에서도 독립적인 상위 계층의 지식구조를 제안하고, 의미 연결, 지식구조, 주제접근, 상호운용성 등을 확보하기 위한 노력이다. FRSAD 모형을 현실적인 정보환경에 적용하고, 도서관 안팎 어디서나 자유롭게 정보를 확인하고 공유하기 위해서는 지식표현 인코딩 체계가 필요하다. 본 연구에서는 웹 온톨로지 언어인 OWL를 사용하여 FRSAD 모형을 온톨로지 구조로 표현하였으며, 이를 확인하기 위해 Prot$\acute{e}$g$\acute{e}$를 사용하여 FRSAD 온톨로지 모형을 시범적으로 구축하였다. Mapping FRSAD and other ontology models intends to suggest a higher knowledge level that is independent of any information implementation system or specific context, and to endeavor to focus on the semantics, knowledge structures, subject access, and interoperability. Providing an application of FRSAD model to information environment and representing and sharing the information within the library sector and beyond, there needs encoding scheme for knowledge representation. This study suggested an OWL based ontology architecture for FRSAD model and demonstrated the pilot FRSAD ontology model using Prot$\acute{e}$g$\acute{e}$ software.

목록의 집중기능을 향상시키는 '원형' 개념에 관한 연구

이혜원,Lee, Hye-Won 한국비블리아학회 2011 한국비블리아학회지 Vol.22 No.3

저작은 목록의 집중기능에 중요한 역할을 하는 서지 개체이다. 본 연구에서는 저작의 개념을 재분석하고, 이미 공표된 FRBR 저작의 개념을 보완할 수 있는 새로운 방안을 모색하고자 하였다. 저작의 집중기능을 향상시킬 수 있는 방안으로 저작보다 한 차원 높은 '원형' 개체를 선언하였고, 원형과 관련된 속성 및 관계를 FRBR 모형과 연결하여 설명하였다. Work is a bibliographic entity serving a key role for the collocation function of catalog. This study analyzed the concept of work, provided a new device to complement conventional FRBR work. The 'prototype' was suggested to enhance the collocation function of catalog, the highest level in FRBR. This study explained the definition, attributes of prototype, and relationships between prototype and work within FRBR model.