국립중앙도서관 귀중서고 내 알데히드류 및 휘발성유기화합물(VOCs)에 대한 건강위해성평가

이혜원,임희빈,이귀복,박소연,전정인,이철민,Lee, Hye-Won,Lim, Hui Been,Lee, Kwi-Bok,Park, So Yeon,Jeon, Jeong In,Lee, Cheol Min 한국환경과학회 2020 한국환경과학회지 Vol.29 No.6

This study investigates the concentration distribution of aldehydes and volatile organic compounds (VOCs) in the archive of the National Library in Korea and evaluates the health risks to workers from hazardous chemicals. Acetaldehyde had the highest concentration among the nine species of aldehydes present in the archive and the concentration of toluene was the highest among the six species of VOCs. Most of the detected substances showed that their indoor concentrations were higher than the outdoor ones, suggesting the possibility of indoor sources of aldehydes and VOCs. The evaluation of health risks for workers based on these measurement results showed that not all substances were hazardous to the human body. However, considering the possibility of the presence of indoor sources and the potential limits of our study owing its short period, it is necessary to conduct long-term studies on the concentration distribution of indoor pollutants in the archive environment.

가토 간내 선택적 담관결찰후 간부피의 변화에 대한 실험적 연구

이혜원,윤엽,고영태,최우석,임주원,오주형,임형택,김윤화,이석환,Lee, Hye Won,Yoon, Yup,Ko, Young Tae,Choi, Woo Suk,Lim, Joo Won,Oh, Joo Hyeong,Rim, Heyong Teck,Kim, Youn Wha,Lee, Seok Hwan 대한영상의학회 1998 대한영상의학회지 Vol.39 No.6

Purpose : To evaluate the role of bile duct obstuction in the development of atrophy of the liver, using ananimal model. Materials and Methods : Seven rabbits were divided into two groups : group 1(n=5), in which therewas selective bile duct ligation, and group 2(n=2), which underwent a sham operation. Each group was evaluatedusing CT for changes in hepatic volume after selective bile duct ligation or a sham operation. In group I, thediameter of dilated bile duct was measured 2, 4, 8, 12 and 16 weeks after bile duct ligation, while gross andhistologic change were evaluated in all cases. Results : In group 1, bile duct dilatation was seen on CT two weeksafter selective bile duct ligation, and did not change significantly during follow-up. In four of five cases, CTrevealed no evidence of significant atrophy of the involved segment. Pathologic specimens, however, revealeddilatation of the bile duct, periductal fibrosis, infiltration of chronic inflammatory cells, and periportalfibrosis. One of five cases showed segmental liver atrophy after selective bile duct ligation. In addion to theabove pathologic findings, there was obstruction of the portal vein by foreign body reaction. In group 2, noevidence of dilated bile duct or liver atrophy was revealed by CT or pathologic specimen after a sham operation.Conclusion : During long-term follow-up of 16 weeks, obstruction of the bile duct did not play a major role in thedevelopment of lobar atrophy in the rabbit.

말기암 환자 가족에 대한 호스피스 팀의 정보적 지지 제공 효과

이혜원,Lee, Hye-Won 한국호스피스협회 2001 호스피스 학술지 Vol.1 No.1

To evaluate the effect of informational support by hospice team on family caregivers of terminally ill cancer patients, 22 family caregivers of D University Hospital in Daegu city were participated. The research was conducted from Aug. 16th to Oct. 28th 2000 by using self-reported questionnaires. The instruments used in this study were the Weinert's scale of perceived social support, Spielberger's state anxiety inventory, CES-D, and Ellison and Paloutzian's spiritual well-being scale. The intervention was designed to give educational and counselling program up to 7 times within 4 weeks. Educational and counselling booklets which made by the researcher were used step by step by hospice team. The data were analysed frequency, percentage, Wilcoxon Singed Ranks Test Test with SPSS Win 10.0/PC. The results obtained from this study were as follows: 1.The perceived social support of family caregivers was significantly increased after ready planned informational support was applied by hospice team(z=-3.045, p=0.002). 2.The anxiety of family caregivers was significantly reduced after ready planned informational support was applied by hospice team(z=-3.348, p=0.001). 3.The depression of family caregivers was significantly reduced after ready planned informational support was applied by hospice team(z=-3.641, p=0.000). 4.The spiritual well-being score of family caregivers was not significantly improved after ready planned informational support was applied by hospice team(z=-0.422, p=0.673). In conclusion, the results of this study clearly suggests that the informational support provided by hospice team not only increased the family caregivers' who are caring for terminally ill cancer patients. Therefor the informational support program designed by researcher for family caregivers who are caring for terminally ill cancer patients should be utilized and expended.

음양곽으로부터 Icariin의 분리 및 함량분석

이혜원,황성원,고병섭,김호경,Lee, Hye-Won,Hwang, Seong-Won,Ko, Byoung-Seob,Kim, Ho-Kyoung 한국생약학회 2001 생약학회지 Vol.32 No.1

Epimedii Herba has been used for tonic, cardiotonic, impotency, amnestic and diuretic. Icariin, a main component was isolated from the Epimedii Herba and identified by the spectroscopic methods. In order to evaluate the quality of Epimedii Herba purchased from various regions of Korea, quantitative determination of icariin in Epimedii Herba using HPLC method has been conducted. Quantitative analysis showed the average amount of icariin in commercial 42 samples was 0.34% on the dry weight basis.

목록의 집중기능을 향상시키는 '원형' 개념에 관한 연구

이혜원,Lee, Hye-Won 한국비블리아학회 2011 한국비블리아학회지 Vol.22 No.3

저작은 목록의 집중기능에 중요한 역할을 하는 서지 개체이다. 본 연구에서는 저작의 개념을 재분석하고, 이미 공표된 FRBR 저작의 개념을 보완할 수 있는 새로운 방안을 모색하고자 하였다. 저작의 집중기능을 향상시킬 수 있는 방안으로 저작보다 한 차원 높은 '원형' 개체를 선언하였고, 원형과 관련된 속성 및 관계를 FRBR 모형과 연결하여 설명하였다. Work is a bibliographic entity serving a key role for the collocation function of catalog. This study analyzed the concept of work, provided a new device to complement conventional FRBR work. The 'prototype' was suggested to enhance the collocation function of catalog, the highest level in FRBR. This study explained the definition, attributes of prototype, and relationships between prototype and work within FRBR model.

이벤트 - 2005서울국제도서전

이혜원,Lee, Hye-Won 대한출판문화협회 2005 출판저널 Vol.356 No.-

온톨로지 구조로 표현된 FRSAD 모형에 관한 연구

이혜원,Lee, Hye-Won 한국비블리아학회 2012 한국비블리아학회지 Vol.23 No.1

FRSAD과 온톨로지 모형간의 연계는 어떠한 정보구현시스템이나 특정 상황에서도 독립적인 상위 계층의 지식구조를 제안하고, 의미 연결, 지식구조, 주제접근, 상호운용성 등을 확보하기 위한 노력이다. FRSAD 모형을 현실적인 정보환경에 적용하고, 도서관 안팎 어디서나 자유롭게 정보를 확인하고 공유하기 위해서는 지식표현 인코딩 체계가 필요하다. 본 연구에서는 웹 온톨로지 언어인 OWL를 사용하여 FRSAD 모형을 온톨로지 구조로 표현하였으며, 이를 확인하기 위해 Prot$\acute{e}$g$\acute{e}$를 사용하여 FRSAD 온톨로지 모형을 시범적으로 구축하였다. Mapping FRSAD and other ontology models intends to suggest a higher knowledge level that is independent of any information implementation system or specific context, and to endeavor to focus on the semantics, knowledge structures, subject access, and interoperability. Providing an application of FRSAD model to information environment and representing and sharing the information within the library sector and beyond, there needs encoding scheme for knowledge representation. This study suggested an OWL based ontology architecture for FRSAD model and demonstrated the pilot FRSAD ontology model using Prot$\acute{e}$g$\acute{e}$ software.

서울국제도서전 결산과 과제

이혜원,Lee, Hye-Won 대한출판문화협회 2004 출판저널 Vol.344 No.-

리튬이차전지 출력측정법의 원리 및 측정법간 비교 연구

이혜원,이용민,Lee, Hye-Won,Lee, Yong-Min 한국전기화학회 2012 한국전기화학회지 Vol.15 No.3

리튬이차전지의 수요가 소형 휴대용 전자기기에서 중대형 전기자동차와 에너지저장장치로 변화함에 따라, 요구되는 전지 특성도 크게 달라지고 있다. 10년 이상의 장기 신뢰성, 팩 수준의 안전성, 가격 경쟁력 확보 등 기존 소형 전지보다 크게 강화된 요구 조건뿐만 아니라, 고출력 특성도 함께 필요로 한다. 그런데, 출력을 측정하기 위해서는 전압과 전류가 동시에 측정 및 제어되어야 하기 때문에, 기존의 단위셀 용량 측정보다 훨씬 어렵다. 또한, 측정 방법의 선택뿐만 아니라 출력유지시간, 충전상태(State-of-Charge, SOC), Cut-off 조건, 측정온도 등의 측정 조건에 따라서도 그 측정값이 크게 달라지는 경향이 있다. 본 논문에서는 HPPC (Hybrid Pulse Power Characterization)법, J-pulse(Japan Electric Vehicle Association Standards, JEVS D 713)법, 정출력 측정법(Constant Power Measurement)의 측정 원리 및 실제 실험에 어떻게 적용해야 하는지 설명하고, HEV(Hybrid Electric Vehicle)용 단위셀을 이용해 출력법간 측정 결과를 비교 분석한다. As the market of lithium secondary batteries moves from mobile IT devices to large-format electric vehicles or energy storage systems, the strengthened battery specifications such as long-term reliability longer than 10 years, pack-level safety and tough competitive price have been required. Moreover, even though high power properties should also be achieved for hybrid electric vehicles, it is not easy to measure accurate power values at various conditions. Because it is difficult to choose a proper measurement method and its experimental condition is more complex comparing to capacity measurement. In addition, the power values are very sensitive to power duration time, state-of-charge (SOC) of cells, cut-off voltages, and temperatures, whereas capacity values are not. In this paper, we introduce three kinds of power measurement methods, hybrid pulse power characterization (HPPC) suggested by US FreedomCar, so-called J-pulse by Japan electric vehicle association standards (JEVS) and constant power measurement, respectively. Moreover, with pouch-type unit cells for HEV, experimental power data are discussed in order to compare each power measurement.

중소도시 일 유방클리닉 방문 여성의 유방암 검진현황 -의무기록을 이용한 후향적 조사연구-

이혜원,김영미,Lee, Hye Won,Kim, Young Mee 한국디지털정책학회 2021 디지털융복합연구 Vol.19 No.10

유방암 환자의 제 특성을 파악하여, 유방암 조기 검진의 중요성과 젊은 유방암의 심각성을 알리기 위해 시행하였다. 2010년 5월 1일부터 2020년 4월 30일까지(10년간) 일 유방 클리닉에 내원한 환자 23,200명 중 유방암으로 진단받은 483명의 의무기록을 이용한 후향적 조사연구이다. 유방암으로 진단받은 483명의 나이는 40대(36.0%)가 가장 많았으며, 30대(25.9%)가 다음으로 많았다. 유방암 가족력이 있는 경우가 5.4%, 폐경 상태는 29.2%였으며, 내원 동기로는 종괴가 54.2%로 가장 많았고, 유방 검진 경험은 출산 경험자가 비출산자보다 많았으며, 20-30대에서 유방검사 경험이 가장 적었다. 젊은 여성을 대상으로 유방암 검진의 중요성을 교육할 필요가 있으며, 유방암의 국가암검진 연령에 대한 재검토를 제언한다. The status of breast cancer screening of women at a breast clinic in a small city in Korea-Using medical records Purpose: This study was conducted to investigate breast cancer incidence by age, including those under 40, and to emphasize the importance of early breast cancer screening for young breast cancer patients. Method: The study was designed as a retrospective survey method. We investigated the medical charts of 483 patients diagnosed with breast cancer among 23,200 visitors to local breast clinic from May 1, 2010 to April 30, 2020. Results: The average age of 483 patients was 47.9, with 36% in their 40s and 28.6% under 40. Among the patients, 5.4% had a family history of breast cancer, and 70.8% were pre-menopausal. The most common reason for visiting the clinic was the mass(54.2%). The size of tumors was less than 2cm (56%), followed by 2-5cm (43.4%) and more than 5cm (5.6%). The size of tumors was smaller in the asymptomatic case than in the symptomatic case. In the pathologic results, invasive ductal cancer was the most common at 80.3%. Conclusions: Breast cancer screening program should be activated even for young women under the age of 40. We suggest educating the importance of breast cancer screening, and lowering the age of national breast cancer screening program.