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      • 사이버 건축의 비물질성에 관한 연구

        이현아,이경훈 대한건축학회 2000 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.20 No.1

        Like the architecture change with the current of the times, the architecture of the digital society change with digital paradigm. A element make a new tradition is learned with continuous advent of a element in history. Like this, it is a study on the relation between cyberarchitecture and current architecture and possibility about cyberarchitecture. For study about the relation cyberarchitecture and current architecture, materiality and immateriality will be considered and consideration about the immateriality. in modern architecture and the immateriality in cyberarchitecture will be preceded.

      • KCI등재

        Anti-Helicobacter pylori activity and inhibition of gastritis by Allium hookeri extract

        이현아,홍선화,유지현,정영호,김옥진 한국실험동물학회 2018 Laboratory Animal Research Vol.34 No.2

        Allium hookeri is widely consumed plant as a vegetable and herbal medicine in southeastern Asia. Allium hookeri has been reported antioxidant, improvement of bone health and antidiabetic effects. In the present study, we investigated the potential inhibitory effect of Allium hookeri extract (AHE) on Helicobacter pylori. The in vitro anti-bacterial activities of AHE were determined by disk agar diffusion method. Also, the inhibition effect of the AHE on H. pylori infection was investigated using a mouse model. H. pylori colonization was confirmed by rapid urease tests, as described previously. Mucosal damage was evaluated grossly and histologically according to previously described criteria. As the results of the disk agar diffusion assay, CLR, AMX and MTZ inhibited the bacterial growth with inhibition zone of 19.2, 15.2 and 7.5 mm, respectively. AHE 100 μg/mL showed an inhibition zone value of 20.6 mm. Rapid urease tests of the mice stomachs demonstrated a significant reduction in H. pylori colonization. In addition to the therapeutic effect against H. pylori infection, the AHE reduced mucosal inflammation and epithelial damages in the stomach of H. pylori-infected mice. These results demonstrate that the AHE successfully cured an H. pylori infection and treated the H. pylori infection. This AHE could be a promising treatment for patients with gastric complaints including gastritis caused by H. pylori.

      • KCI등재

        중등도 이상의 위험 수술을 받은 환자에서 수술 전후 항혈전제 약물 사용 평가

        이현아,조윤희,조윤숙,한현주,이주연,정근화,이상건,Lee, Hyeon-Ah,Jo, Yun Hee,Cho, Yoonsook,Hahn, Hyeon Joo,Lee, Ju-Yeun,Jung, Keun-Hwa,Lee, Sang Kun 한국임상약학회 2017 한국임상약학회지 Vol.27 No.1

        Objective: The perioperative management of antithrombotic therapy is often challenging and it requires a fine balance between the risk of hemorrhage and thrombosis. We aimed to evaluate the antithrombotic management for moderate to high risk patients in real world setting. Methods: Among the patients who were consulted to the neurologist for the evaluation of perioperative risk from 2010 to 2012, patients undergoing moderate to high risk surgery and taking antithrombotics within 30 days were identified. We analyzed the timing of discontinuation and reinitiation of antithrombotic drugs before or after surgery as well as the status of bridging therapy. In addition, the conformity with the guideline suggested by American College of Chest Physicians was assessed. The rate of thromboembolic event and major hemorrhage were also investigated. Results: A total of 329 patients were included. The concordance rate of warfarin stop and restart time with guideline was 23.4% and 10.3%, respectively. Continuing aspirin in patients undergoing coronary artery bypass surgery or non-cardiac surgery in patients with high risk for cardiovascular events were 59.2% and 2.6%, respectively. Bridging therapy was adopted in 92.9% and 81.2% in patients who had received anticoagulant before surgery and who were at high and low risk thromboembolism, respectively. In entire cohorts, 30-day incidence of major bleeding and thromboembolic event were 31.9% and 3.0%. Co-morbid renal disease were shown as independent predictor for major bleeding (adjusted OR 2.65. 95% CI 1.33-5.28). Conclusion: The concordance rate with guideline regarding perioperative antithrombotic use was low and bridging therapy was prevalent in patients undergoing moderate to high risk surgery.

      • KCI등재

        주의력 결핍-과잉행동장애아동의 주의력 수준이 CPT와 WCST수행에 미치는 효과

        이현아,박형배,배대석,백용매 大韓神經精神醫學會 2001 신경정신의학 Vol.40 No.4

        연구목적 : 본 연구는 주의력 결핍-과잉행동장애 아동과 정상아동의 주의력 수준이 CPT와 WCST수행에 미치는 영향을 검토하여 ADHD아동의 특징적인 인지결함을 알아보고자 하였다. 방 법 : 1999년 12월부터 2000년 4월까지 Y대학 의료원 소아정신과를 방문하여 ADHD로 진단된 아동들을 K-ABC의 하위검사인 수회생검사를 실시하여 주의력 낮은 집단(N=18),중간집단(N=18), 높은 집단 (N=18)로 분류하였고 주의력 수준에 따라 분류된 ADHD집단에게 지능검사와 CPT및 WCST를 실시하였다. 또한 정상아동에게도 수회생 검사를 통해 ADHD아동중 주의력 수준이 높은 집단과 동일한 주의력을 가진 아동을 선정한 후 이들에게도 ADHD아동과 동일한 검사를 실시하여 수행을 비교하였다. 결 과 : 본 연구의 결과를 요약하면 다음과 같다. CPT하위검사중 누락오류와 오경보 오류에서 ADHD집단과 정상집단간에는 의미있는 차이가 나타나지 않았고, ADHD집단내에서도 주의력의 수준에 따른 차이는 없었다. 그러나 WCST수행의 경우 ADHD의 각 하위집단간에 주의력 수준에 따른 차이는 없었으나, 정상집단에 비해서는 ADHD집단의 수행이 저조한 것으로 나타났다. 결 론 : ADHD아동의 특징적인 인지결함은 단순한 주의력의 결함이 아니라 자극이 선택되어 실행에 이르기까지의 과정인 정보처리과정 중 주의력의 감독, 자기조절, 억제과정과 같은 보다 고차적인 인지기능인실행기능에 문제가 있음을 확인할 수 있었다. 따라서 ADHD아동의 치료를 위해서도 단순한 주의력 결핍의 개선보다는 문제해결능력과 계획력, 충동성 같은 인지행동을 변화시키기 위한 치료전략이 필요한 것으로 생각된다. Objectives : The purpose of this study was to investigate the effects of attention level in normal children and Attention Deficit Hyperactivity Disorder(ADHD) children on Continuous Performance Test(CPT) and Wisconsin Card Sorting Test(WCST) performances. Methods : For this survey, the ADHD children were classified into low, medium, and high attention groups according to the attention level. Normal Group of Children, Chosen for their same attention level as that of high attention level group among ADHD groups, was compared in their CPT and WCST performances with ADHD groups. Results : The findings of the study were as follows. 1) the ADHD groups distinguished by their attention level ; in other words, the low, medium, and high attention level groups ; showed no differences in CPT performances. This means the unique cognitive deficit of ADHD group is not the character of attention capacity limit. 2) the ADHD group showed lower performances on WCST than the normal group, regardless of attention level. Conclusion : ADHD group have a deficit in the ability or regulation stategy, adaptability of attention, and non appropriate response, which are needed for efficient division of prescribed information processing. These results imply that the cognitive deficit of ADHD is a character which shows that the execution deficit, which is a higher cognitive function, is a cognitive deficit of ADHD group, rather than simple attention deficit.

      • 여성과 권한부여 사회복지실천 모델 : An Empowering Approach for Women

        이현아 서울神學大學校 2005 교수논총 = (A)collection of treatises Vol.17 No.-

        This article discusses feminist social work practice delineating the concept of empowerment for women. Empowerment approach, which makes connection between social and economic justice and between individual suffering and pain, is based on simultaneous concern for people and environment. Empowering practice with women on personal, interpersonal, and political level is geared toward promoting competence and building on people's strengths, resiliency, and resources. Empowerment refers to the process by which individuals and groups gain power, access to resources, and control over their own lives. Empowerment of women involves the processes of increasing self-efficacy, developing a group consciousness, reducing self-blame, assuming personal responsibility and changing oppressive structures. Following techniques to place the client in a position of power and control are suggested: accepting the client's definition of the problem, identifying and building upon existing strength, engaging in a power analysis of the situation, teaching specific skills, and mobilizing resources or advocating for client.

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