호남대학교 특성화사업 지역산업(스마트가전) 맞춤형 ICT융복합 기술인력 양성사업단

이양원,Lee, Yang-Won 한국공학교육학회 2016 공학교육동향 Vol.23 No.3

아메드 방수유출장치 삽입수술의 성공과 관련된 요인

이양원,임진호,이성복,김창식,Yang-Won Lee,M,D,Jin-Ho Yim,M,D,Sung-Bok Lee,M,D,Chang-Sik Kim,M,D 대한안과학회 2005 대한안과학회지 Vol.46 No.9

Purpose: To evaluate the factors associated with the success of Ahmed glaucoma valve implantation in refractory glaucoma. Methods: The medical records of 45 eyes of 45 patients that underwent Ahmed implant surgery for the treatment of refractory glaucoma were reviewed retrospectively. The success criterion was a stable postoperative intraocular pressure (IOP) between 6 and 21 mmHg with or without antiglaucoma medications during the study period. Failure was defined as an abnormal IOP outside of the above range on two consecutive visits, and cases that needed additional surgery to control IOP or to treat devastating surgical complications. We compared the differences in various clinical factors before surgery between the success and failure groups. Results: The Kaplan-Meier cumulative success rate was 71.1% at 12 months. Among the various clinical factors age, gender, right or left eye, phakia or pseudophakia, systemic disease such as diabetes and hypertension, preoperative IOP, preoperative number of antiglaucoma medications, and the number of previous glaucoma or other ocular surgeries were not significantly different between the success and failure groups. Implantation at the superotemporal site and steroid non-responsders of the fellow eye showed a significantly greater success rate than the superonasal site and steroid responders, respectively, after Ahmed glaucoma valve implantation. Conclusions: The efficacy of lowering the IOP of an Ahmed glaucoma valve would be expected to be greater if the patient is a steroid non-responder. Given the same conditions in the superotemporal and superonasal areas, implanting the Ahmed glaucoma valve in the superotemporal quadrant showed an ito increased success rate.

클라우드 서버 기반 IoT를 이용한 무선기지국 원격 감시시스템 개발

이양원,김철원,Lee, Yang-weon,Kim, Chul-won 한국정보통신학회 2018 한국정보통신학회논문지 Vol.22 No.6

넓은 지역에 광범위하게 분포되어 있는 통신용 무선기지국은 관리에 많은 어려움이 있다. 특히 산간 오지에 있는 무인 통신무선 기지국은 위급한 상황 발생시에 접근에 많은 어려움을 겪고 있다. 대형 통신회사들은 송수신 정보만 원격으로 관리하고 있고 실제 시설 유지를 책임지고 있는 지역 중소기업 협력업체들은 이러한 기술을 보유하고 있지 않아서 일일이 현장 방문을 통하여 확인하고 있는 실정이다. 본 연구에서는 넓은 범위에 산재해 있는 무선기지국내의 온도, 습도, 화염 발생여부, 전원 동작 여부를 실시간으로 모니터링 하여 클라우드 서버에 보내 사무실에서 실시간 모니터링을 통하여 관리하며 위급시 경고 메시지 전송 등이 수행이 가능한 시스템을 클라우드 서버 구축을 통하여 IoT 센서 기술을 이용하여 구현한 내용을 제시하고자 한다. Radio base stations, which are widely distributed across large areas, have many difficulties in managing them. Unmanned radio base stations in remote mountains are having a hard time accessing them in case of emergencies. Major telephone service providers only remotely control incoming and outgoing information and local small business partners responsible for maintaining actual facilities do not possess such technologies, so they are each checked during field visits. In this study, in order to process the sensor raw data and smoothing, we apply the particle filters and confirmed that the performance of sensor data accuracy is increased. Integrated system using temperature, humidity, fire condition, and power operation at a wide range of radio base stations under the real-time monitoring status is operated well. It show that all of the status of base station are monitored at the remote office using the cloud server through internet networking.

Particle Filter를 이용한 제스처 인식 연구

이양원,김철원,Lee, Yang-Weon,Kim, Chul-Won 한국정보통신학회 2006 한국정보통신학회논문지 Vol.10 No.11

The recognition of human gestures in image sequences is an important and challenging problem that enables a host of human-computer interaction applications. This paper describes a gesture recognition algorithm based on the particle filters, namely CONDENSATION. The particle filter is more efficient than any other tracking algorithm because the tracking mechanism follows Bayesian estimation rule of conditional probability propagation. We used two models for the evaluation of particle Inter and apply the MATLAB for the preprocessing of the image sequence. But we implement the particle filter using the C++ to get the high speed processing. In the experimental results, it is demonstrated that the proposed algorithm prove to be robust in the cluttered environment. 연속되는 이미지 중에서 인간의 동작을 인식하는 것은 인간과 컴퓨터 의 상호 작용에서 매우 중요하고 도전할 분야이다. 본 논문에서는 CONDENSATION 알고리즘을 이용하여 입자 필터(particle filter)에 기반한 동작 인식 알고리즘을 제안한다. 입자 필터는 조건 확률 전파 모델(Conditional Density Propagation)인 베이시안(Bayesian) 추정 규칙을 적용하는 추적구조를 갖고 있기 때문에 다른 어떤 종류의 추적 알고리즘보다 뛰어난 성능을 보인다. 본 논문에서는 알고리즘의 성능평가를 위해서 두 개의 동작 모델을 가정하였고, 영상에 대한 전처리를 위해서는 MATLAB를 이용하였으며 입자필터는 고속 처리를 위하여 C++로 구현하였다. 두 개의 동작 실험 결과를 통해, 동작 인식 입자 필터가 복잡한 환경 속에서 강인한 추적 성능을 나타냄을 확인하였다.

물과기름의 상극성을 완화시키는 안정제-유화제

이양원,Lee, Yang-Won 대한제과협회 1996 베이커리 Vol.10 No.-

An Integrated Approach to the GIS Data Reengineering for the New Korea Geodetic Datum

이양원(Yang-Won Lee),박기호(Key-Ho Park) 대한지리학회 2005 대한지리학회지 Vol.40 No.2

세계측지계의 도입에 따라 광범위한 공간데이터의 재정비가 필요하게 되었다. 이 연구에서는 이를 위한 통합모델로서 상호운 용성과 표준화 및 공간DB 활용에 기반한 구체적인 전략과 시범시스템을 제시한다. 세계측지계를 위한 지도데이터 변환은 파일변환과 공간DB 변환, 그리고 파일-공간DB 상호간 변환의 형태로 이루어질 수 있다. 이 연구에서 개발한 통합모델은 기존의 파일형식(예컨대, DXF와 Shapefile)은 물론 새로운 표준으로 권장되는 파일형식 (예컨대, GML과 SVG)의 세계측지계 변환이 파일형식 상호간에 이루어지도록 한다. 이러한 지도파일들은 세계측지계 변환모듈을 거쳐 공간DB로 임포트되거나 공간DB로부터 익스포트될 수 있다. 또한, 공간DB의 세계측지계 변환은 단일 DB 내부변환과 함께 이질적인 DB간의 변환 (예컨대, SDE/Oracle과 Oracle Spatial)을 포함한다. 이 연구의 세계측지계 변환시스템은 다중컴퓨팅 환경을 고려하여 데스크탑과 인터넷 기반에서 동시에 운영되도록 구현되었다. 시험운영과 평가를 통해 본 연구에서 제안한 통합모델의 상호운용성과 타당성이 검증되었으며 또한 좌표변환의 결과도 기존 연구의 결과물과 일치함을 확인하였다. The newly adopted Korea Geodetic Datum (a.k.a. KGD2002) calls for massive reengineering work on geospatial dataset. The main focus of our study is placed on the strategy and system implementations of the required data reengineering with a keen attention to integrated approaches to interoperability, standardization, and database utilization. Our reengineering strategy includes file-to-file, file-to-DB, DB-to-file, and DB-to-DB conversion for the coordinate transformation of KGD2002. In addition to the map formats of existing standards such as DXF and Shapefile, the newly recommended standards such as GML and SVG are also accommodated in our reengineering environment. These four types of standard format may be imported into and exported from spatial database via KGD2002 transformation component. The DB-to-DB conversion, in particular, includes not only intra-database conversion but also inter-database conversion between SDE/Oracle and Oracle Spatial. All these implementations were carried out in multiple computing environments: desktop and the Web. The feasibility test of our system shows that the coordinate differences between Bessel and GRS80 ellipsoid agree with the criteria presented in the existing researches.

Amore Pacific Scholarship Report-6 (ASR-6) : Understanding Malassezia yeast using functional genomics

이양원 ( Yang Won Lee ) 대한피부과학회 2014 대한피부과학회 학술발표대회집 Vol.66 No.2

Malassezia yeasts are lipophilic fungi that are recovered in 75-98% of healthy adults. The yeasts, since being first introduced in 1889, have been linked to various skin conditions such as pityriasis versicolor, seborrheic dermatitis, and Malassezia folliculitis, and most recently, atopic dermatitis. Its pathogenic ability is drawing attention more than ever as cases of confluent and reticulated papillomatosis and Malassezia onychomycosis, as well as systemic Malassezia infection in immunocompromised adults and neonates receiving intravenous fluid replacement have recently been reported. Conventional studies and identification on Malassezia yeasts have traditionally been based on morphological and biochemical analyses. However, these methods often have dubious criteria, and environmental factors and genetic mutations are giving rise to new species. Therefore, new molecular biological methods, which would overcome these limitations, are now in demand. The authors have already reported successful identification of Malassezia yeasts using 26S rDNA PCR-RFLP (polymerase chain reaction-restriction fragment polymorphism) and pyrosequencing. RFLP methods enable us to analyze the pattern and size of fragmented amplified ribosomal DNA with the use of two restriction enzymes, Hha1, and BstF1. With these methods, genetic diversity can be examined, and it can be widely used in the rapid diagnosis and epidemiological study of fungal species because it is rapid, precise and cost-effective. In addition, the pyrosequencing method, which has recently been brought into the spotlight, enables us to identify the species with only a 30-40 bp sequence.. Among Malassezia spp., M. globosa and M. restricta were most frequently isolated from patients with dermatitis. Furthermore, M. restricta was known to be the predominant species among Korean teens and young adults. Almost all Malassezia spp. Are obligatorily lipid-dependent, which might be caused by lack of the myristic acid synthesis.the precursor of long chain fatty acids. The cell wall of Malassezia spp. contains significantly higher lipid contents than non-pathogenic fungi, such as Saccharomyces cerevisiae, implying that lipid-dependency of the fungus plays a role in virulence.Recent genome analysis of M. globosa suggested that the absence of a gene encoding fatty acid synthase might be compensated by abundant genes encoding hydrolases that produce fatty acids. The genome of M. globosa possesses 14 lipases and 9 phospholipases, and the study showed that many of them were expressed on human scalp to use host lipids. These results led us to investigate contributions of lipases and phospholipases in virulence of M. restricta as being the most frequently isolated Malassezia spp. within the Korean population. We searched the unannotated and incomplete M. restricta genome for a lipase and a phospholipase with M. globosa sequences and found three and one homologs respectively. Culture-independent sequencing methods confirmed a tight association of Malassezia species with various skin sites of the human body. It was also suggested that fungal infection is associated with fungal community imbalance and that antifungal treatment may cause alterations of skin fungal communities The nasal microbiome is considered an important contributor to human health, though no studies have yet been conducted to fully analyze the phylogenetic composition of fungal communities. We also investigated the influence of allergic rhinitis(AR) on the nasal mycobiome, focusing on fungal communities on the nasal vestibule skin surface, which is the most anterior part of the nasal cavity, in patients with AR compared to healthy individuals

Ohun Memorial Lecture : Evaluation of expression of lipases and phospholipases of Malassezia restricta in patients with seborrheic dermatitis

이양원 ( Yang Won Lee ) 대한피부과학회 2014 대한피부과학회 학술발표대회집 Vol.66 No.2

Basidiomycete yeasts Malassezia species (spp.) are cutaneous microflora and are considered as opportunistic pathogens. Malassezia are associated with various dermatological diseases including seborrheic dermatitis, dandruff and atopic dermatitis. Among Malassezia spp., M. globosa and M. restricta were most frequently isolated from patients with dermatitis. Furthermore, M. restricta was known to be the predominant species among Korean teens and young adults. Almost all Malassezia spp. Are obligatorily lipid-dependent, which might be caused by lack of the myristic acid synthesis.the precursor of long chain fatty acids. The cell wall of Malassezia spp. contains significantly higher lipid contents than non-pathogenic fungi, such as S accharomyces cerevisiae, implying that lipid-dependency of the fungus plays a role in virulence. Recent genome analysis of M. globosa suggested that the absence of a gene encoding fatty acid synthase might be compensated by abundant genes encoding hydrolases that produce fatty acids. The genome of M. globosa possesses 14 lipases and 9 phospholipases, and the study showed that many of them were expressed on human scalp to use host lipids. These results led us to investigate contributions of lipases and phospholipases in virulence of M. restricta as being the most frequently isolated Malassezia spp. within the Korean population. We searched the unannotated and incomplete M. restricta genome for a lipase and a phospholipase with M. globosa sequences and found three and one homologs respectively. The sequences of lipase and phospholipase homologs were used to design M. restricta specific primers for the current study. To investigate the expression of three lipases and a phospholipase of M. restricta, swap samples of two different body sites of at least 18 patients with seborrheic dermatitis were obtained, and the total RNA was directly extracted. Reverse transcription-polymerase chain reaction (RT-PCR) was performed and nested polymerase chain reaction (PCR) was carried out using M. restricta specific primers for lipases and phospholipases. Our results indicated that M. restricta was presented in body sites of patients and suggested that majority of the patients display expression of lipase RES_0242.

표피 멜라닌 세포성 병변에 대한 Intense Pulsed Light의 치료효과

이양원 ( Lee Yang Won ),최용범 ( Choe Yong Beom ),안규중 ( An Gyu Jung ) 대한피부과학회 2004 대한피부과학회지 Vol.42 No.2

N/A Background: Intense pulsed light(IPL) systems are high intensity pulsed sources which emit noncoherent, defocused, polychromatic light in a broad wavelength spectrum of 400-1200㎚. The mechanism of action of such light systems corresponds to the selective photothermolysis. Nowdays, IPL system widely used in dermatologic field such as unwanted hair removal, epidermal melanocytic lesions, vascular lesions, and photorejuvenation Objective: The purpose of this study was to evaluate the clinical results of diverse epidermal melanocytic lesions after treatment with an IPL source. Method: Twenty patients with epidermal melanocytic lesions were enlisted. IPL treatment was administered to the patients in a 4-week sessions. Irradiation wavelength was controlled using cutoff filters ranging from 400 to 700㎚, with a fluence of 10-13.5j/㎝2 with double pulse illumination and a pulse width of 7mses. Results: By the end of the study, three attending physicians assessed the results for 85% of the subjects as excellent or good, with 85% of the patients reporting that same results; however, heep lesion such as Becker`s nevus showed an average clearance of fair. No specific adverse effects except two case of blisters were observed after treatment. Conclusion: Treatment of epidermal melanocytic lesions in Asian skin using IPL is an effective, safe, and rapid treatment, with relatively few side effects and high patient satisfaction. (Korean J Dermatol 2004;42(2):145~150)

Atopic dermatitis and systemic comorbities

이양원 ( Yang Won Lee ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.1