저혈당성 경련으로 내원한 환자에서 진단된 Silver-Russell 증후군 1례

이경연,이정용,김영아,오기원,김자형,김준성,정진영,박상규 대한소아신경학회 2010 대한소아신경학회지 Vol.18 No.1

The Silver-Russell syndrome(SRS) is a clinically heterogeneous syndrome characterized by intrauterine and postnatal growth retardation with spared cranial growth, characteristic facial features, and body asymmetry. Although mild to moderate hypoglycemic symptoms occasionally appear in children with SRS especially those who are not fed frequently and regularly, hypoglycemic seizures rarely occur. We report a rare case of SRS which was diagnosed in a 4-year-old female who admitted with hypoglycemic seizure. The patient showed the characteristic features of SRS. Endocrinologic studies were normal except for partial growth hormone insufficiency. To prevent seizures and chronic neurologic deficits in children with SRS, the early recognition and appropriate management of hypoglycemia is critical. 저자들은 저혈당성 경련을 주소로 내원한 4세 여아에서 자궁 내 성장 지연, 출생 후 지속되는 저신장과 저체중, 몸에 비해 상대적으로 큰 머리, 신체의 좌우 비대칭, 특징적인 얼굴 모양을 보인 Silver- Russell 증후군 1례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

직하방과 빗각 촬영 운용을 위한 초분광 영상센서 구동방식에 관한 연구

이경연 한국군사과학기술학회 2019 한국군사과학기술학회지 Vol.22 No.4

General Hyperspectral Image Sensor acquires an image of line form such as a thin rectangle shape because of using 1D array Push Broom or Whisk Broom scanning method. A special mechanism is required for a Hyperspectral Image Sensor to operate for nadir and slant range. To design the mechanism, the characteristics of the flight motion and the overlap rate between consecutive frames were analyzed. Also, system requirements were proposed through modeling and simulation.

초극소 미숙아에서 미숙아 망막증 진단 후 Threshold 미숙아 망막증으로의 진행에 영향을 미치는 위험인자

이경연,지윤희,장무환,장영표 대한소아청소년과학회 2002 Clinical and Experimental Pediatrics (CEP) Vol.45 No.11

도심 속 도로변 녹지공간에 대한 정원으로서의 대안적 접근

이경연,주이슬,이경미 (사)한국정원디자인학회 2020 한국정원디자인학회지 Vol.6 No.3

In metropolitan city where space for garden is extremely scarce, interest in the use of unused space is increasing to secure space for gardens near living areas. This Study tried to find out the possibility of using the street unused space as a garden. In the study, the four street gardens where reflecting recent garden trends were selected, then planted plants were investigated. Planting combination analysis was conducted based on the four visual elements of plants, such as color, form, texture, and height. In the study sites, it was found that herbaceous plants were planted in the highest proportion, and most of woody plants were short shrubs. In addition, as reflecting the natural planting style that represents the recent garden trends, a complex planting combination was used, such as making mass planting by mixing grass, and emphasizing planting using various flower types. It was found that the use of color has changed from the style that mainly used green and add the strong color as a point, to the style that create a calm atmosphere using white, purple, or light pink. The planting combination type has changed from the using of woody plants to herbaceous plants, and a planting combination using grass with a fine texture has emerged. This shows the changing of trend form a planting combination that only considered color to a more complex planting combination that considers both color, shape and texture. 녹지를 위한 공간이 극히 부족한 대도시에서 생활권 내 정원을 위한 공간 확보를 위해 사용되고 있지 않은 유휴공간의 활용에 관한 관심이 높아지고 있다. 본 연구는 유휴공간 중 일상생활에서 빈번히 접할 수 있는 가로공간의 정원으로서 활용 가능성에 대해 알아보고자 하였다. 단순 목본류 위주의 기존 가로수와 차별되는 정원 트랜드를 반영한 초본류 중심으로 조성된 도로변 녹지공간 4개소를 대상으로 식재식물을 조사하였고, 식물이 가지는 시각적 요소인 색, 형태, 질감, 높이 4가지 요소를 바탕으로 식재조합을 분석하였다. 연구대상지의 식재식물은 초본류가 가장 높은 비율을 차지하였고, 목본류의 경우 대다수가 키가 작은 관목 위주로 식재된 것을 볼 수 있었다. 또한, 최근 정원 경향을 나타내는 자연적인 식재 스타일을 반영하듯 그래스류를 혼식하여 풍성한 부피식재를 하고, 수직형, 구형 등 다양한 꽃 형태를 가진 초화류를 이용하여 강조식재를 하는 등 복합적인 식재조합을 만들어 주었다. 색상의 사용은 과거 초록색 위주에 강렬한 원색을 포인트로 사용하던 스타일에서 흰색이나 보라색, 연한 분홍색 등을 이용한 차분한 분위기에 주황색, 노란색 등을 이용하여 활기를 더하는 식재조합을 선호하는 경향으로 변화하고 있는 것으로 나타났다. 목본류 중심에서 꽃의 형태가 다양한 초본류 위주의 식재형태로 변화하였고, 고운 질감을 가진 그래스류를 사용한 풍성한 식재조합이 새롭게 등장하고 있다. 이는 단순히 색상 중심이었던 식재조합에서 형태와 질감을 더해 더 복합적인 식재조합으로 변하는 추세를 보여주고 있다.

울산 대곡천 암각화 유 적지 일대의 참나무림 다양성과 분 포 특 성

이경연,김종원 한국수생태학회(구 한국하천호수학회) 2017 생태와 환경 Vol.50 No.1

We describe characteristics of diversity and distribution of oak forests on the Daegok-cheon gorge of the Southeastern Korean Peninsula, the oldest prehistoric site, in view of a sort of food resources of acorns. The Z?rich-Montpellier School’s method was adopted for field investigation on the oak dominant stands. A total of 20 phytosociological relev?s composed of 193 taxa were analyzed by syntaxonomy and ecological flora. The Daegok-cheon’s oak forests occupied 36.9% (513,374 m2) of the surveyed area, and its 99% (507,677 m2) was Quercus variabilis and Q. serrata stands. Oak forests of the Daegok-cheon gorge are a kind of regional vegetation type characterizing by the high relative net contribution degree (r-NCD) of Platycarya strobilacea and Sapium japonicum, which are an edaphic type of the xerophilous and thermophilic oak forests. The region of the Daegok-cheon petroglyphs is defined as an ecoregion with rich acorn supply and abundant water resources, and the warmer environment, which attracts prehistoric man.

Asymptomatic moyamoya syndrome,atlantoaxial subluxation and basal ganglia calcification in a child with Down syndrome

이경연,이근수,원영철 대한소아청소년과학회 2013 Clinical and Experimental Pediatrics (CEP) Vol.56 No.12

Down syndrome, the most common chromosomal abnormality, may be associated with various neurologic complications such as moyamoya syndrome, cervical spinal cord compression due to atlantoaxial subluxation, and basal ganglia damage, as well as epileptic seizures and stroke. Many cases of Down syndrome accompanied by isolated neurologic manifestations have been reported in children; however,Down syndrome with multiple neurologic conditions is rare. Here, we have reported a case of Down syndrome in a 10-year-old girl who presented with asymptomatic moyamoya syndrome, atlantoaxial subluxation with spinal cord compression, and basal ganglia calcification. To the best of our knowledge, this is the first report of Down syndrome, in a child, which was accompanied by these 3 neurologic complications simultaneously. As seen in this case, patients with Down syndrome may have neurologic conditions without any obvious neurologic symptoms; hence, patients with Down syndrome should be carefully examined for the presence of neurologic conditions.

Neurologic Manifestations of Enterovirus 71 Infection in Korea

이경연,이명숙,김동빈 대한의학회 2016 Journal of Korean medical science Vol.31 No.4

Enterovirus 71 frequently involves the central nervous system and may present with a variety of neurologic manifestations. Here, we aimed to describe the clinical features, magnetic resonance imaging (MRI) findings, and cerebrospinal fluid (CSF) profiles of patients presenting with neurologic complications of enterovirus 71 infection. We retrospectively reviewed the records of 31 pediatric patients hospitalized with acute neurologic manifestations accompanied by confirmed enterovirus 71 infection at Ulsan University Hospital between 2010 and 2014. The patients’ mean age was 2.9 ± 5.5 years (range, 18 days to 12 years), and 80.6% of patients were less than 4 years old. Based on their clinical features, the patients were classified into 4 clinical groups: brainstem encephalitis (n = 21), meningitis (n = 7), encephalitis (n = 2), and acute flaccid paralysis (n = 1). The common neurologic symptoms included myoclonus (58.1%), lethargy (54.8%), irritability (54.8%), vomiting (48.4%), ataxia (38.7%), and tremor (35.5%). Twenty-five patients underwent an MRI scan; of these, 14 (56.0%) revealed the characteristic increased T2 signal intensity in the posterior region of the brainstem and bilateral cerebellar dentate nuclei. Twenty-six of 30 patients (86.7%) showed CSF pleocytosis. Thirty patients (96.8%) recovered completely without any neurologic deficits; one patient (3.2%) died due to pulmonary hemorrhage and shock. In the present study, brainstem encephalitis was the most common neurologic manifestation of enterovirus 71 infection. The characteristic clinical symptoms such as myoclonus, ataxia, and tremor in conjunction with CSF pleocytosis and brainstem lesions on MR images are pathognomonic for diagnosis of neurologic involvement by enterovirus 71 infection.

Threshold of Toxicological Concern 기법을 활용한 생활화학제품의 위해성 평가

이경연,박영재,장재익,정진섭,윤지수,김형수,임경민,최달웅 한국동물실험대체법학회 2022 동물실험대체법학회지 Vol.16 No.1

People are exposed to various consumer chemicals products whose toxicity is not well characterized. Among them, plastics are one of the most widely used household chemical products that many people encounter in daily life. In particular, the safety of chemical substances migrated from plastic containers and packages for foods needs to be properly assessed because a number of low-molecular substances including additives, may be directly ingested orally. Because there are many migrated substances with insufficient toxicity data, TTC approach is useful for risk assessment of various house hold chemical product, instead of conventional animal experiments. Here, migration experiments were conducted with fatty food simulants for the five most distributed materials in Korea, and non-target screening analysis was performed with GC-MS. The migrated chemicals were either intentionally added to plastics or unintentionally produced. In order to confirm its safety, risk assessment was conducted by applying the actual toxicity guidance value if available, or the TTC values for respective Cramer class. The risk was about 1.6 times different between two approach, confirming that it is possible to use the TTC for risk assessment of various house hold chemical products.

두피 피부 무형성증을 동반한 양막대증후군 1례

이경연,김자형,정진영,박상규,김준성,오기원 대한신생아학회 2009 Neonatal medicine Vol.16 No.1

The amniotic band syndrome is an uncommon congenital fetal abnormality, presumably due to fetal entanglement in strands of ruptured amniotic sac. The defects caused by this syndrome vary from simple limb defects to major visceral and craniofacial defects. We cared for a newborn infant with this syndrome, who showed constriction rings of the right leg and right axilla, right club foot, thoracic scoliosis, polydactyly, absence of the right thumb and aplasia cutis of the scalp. We report this case with a brief review of the literature.

창작동요를 활용한 놀이 중심 활동이 만 3세 유아의 음악적 표현능력과 놀이성에 미치는 효과

이경연,김진희 학습자중심교과교육학회 2023 학습자중심교과교육연구 Vol.23 No.19

Objectives The purpose of this study is to investigate the effects of play-centered activities utilizing original children's songs on the musical expression abilities and playfulness of three-year-old children. Methods The study focused on 40 children aged 3, attending the preschool class at S Kindergartens in Seoul. In the experimental group, play-centered activities utilizing original children's songs were implemented for 16 weeks, while the comparison group engaged in music-centered activities based on the Nuri curriculum for the same duration. Measurement tools included the music expression ability assessment tool revised and refined by Kim Kwang-ja (2004), and the playfulness assessment tool revised and refined by Kim Young-hee (1995). To validate the educational effects of play-centered activities using age-appropriate songs, pre- and post-tests were conducted on children from both the experimental and comparison groups. The independent samples t-test was performed and analyzed using the SPSS 18.0 program. Results The research findings indicate that, firstly, play-centered activities utilizing original children's songs were effective in enhancing the musical expression abilities of children, including singing, playing musical instruments, body expression, and creating music. Secondly, these play-centered activities were also effective in improving children's playfulness, including physical spontaneity, social spontaneity, cognitive spontaneity, expression of joy, and sense of humor. Conclusions This indicates the significance of utilizing play-centered activities with original children's songs for enhancing the musical expression ability and playfulness of 3-year-old children. This study holds importance in moving away from the traditional teacher-centered approach of planned song instruction, and instead, assisting teachers to actively employ original children's songs, thus aiding in the understanding and implementation of child-led play activities.