탈지분유 함유 식이를 섭취하는 흰쥐에서 칼슘과 비타민 D 수준이 무기질 대사에 미치는 영향

이경민,이연주,원은숙,이상선,Lee, Kyung-Min,Lee, Yeon Joo,Won, Eun-Sook,Lee, Sang Sun 한국식품영양학회 2014 韓國食品營養學會誌 Vol.27 No.4

The purpose of this study was to investigate the effect of calcium (Ca) and vitamin D (vit. D) levels on metabolism of various minerals such as Ca, P, Mg, Fe, Zn, Cu, and Cr. The comparison was made on the rats that were placed on diet containing powdered skim milk with different Ca and vit. D levels for 5 weeks. A total of 42 5-week-old Sprague-Dawley rats were divided into 7 groups as follows: Control group consisted of normal Ca and normal vit. D (0.5% Ca, 1,000 IU vit. D); Experimental groups were divided into low (0.25%) and high (1.0%) calcium levels; and vit. D group was divided into low (10 IU), normal (1,000 IU), and high (5,000 IU) subgroups. The weight gain and food efficiency ratios of the rats were not significantly different with increasing dietary Ca levels. The absorption rates of 7 minerals (Ca, P, Mg, Fe, Zn, Cu, and Cr) were significantly decreased with increasing dietary Ca levels. Also, fecal excretion of P significantly increased with increasing dietary vit. D levels (p<0.05), and urine excretion of Fe was significantly increased with increasing dietary vit. D levels (p<0.001). The result indicated that higher Ca intake affected on bioavailability of other minerals, due to interactions among minerals in the process of intestinal absorption. However, vitamin D intake had no effect on bioavailability of several minerals. Therefore, it could be suggested that adequate Ca intake is important for balance of the minerals.

위화(胃火) 1호(號)로 호전(好轉)된 만성위염(慢性胃炎) 환자(患者) 치험(治驗) 2례(例)

이경민,이세연,임성철,서정철,한상원,Lee, Kyung-min,Lee, Se-yun,Im, Sung-chul,Seo, Jung-chul,Han, Sang-won 대한침구의학회 2003 대한침구의학회지 Vol.20 No.6

Objective: This study was designed to investigate the effect of Wihwa herbal-acupuncture on chronic gastritis. Methods: Wihwa herbal-acupuncture was administered two times a week. The following points were selected: CV12(中脘), CV13(上脘), S36(足三里), Liv3(太衝). We checked pain rating score(P.R.S.), visual analogue scale (V.A.S.) and Gastroscopy. Results: After 6 weeks of treatment, the patient showed that clinical symtoms was disappeared, Lee's P.R.S. changed from 77 to 8 and Park's P.R.S. from 55 to 0 and gastric erosion disappeared on gastroscopy. Conclusions: These results suggest that and Wihwa herbal-acupuncture has good effect on chronic gastritis. But further studies are required to concretely prove the effectiveness of Wihwa herbal-acupuncture for treating chronic gastritis.

새로운 Boosted 3-D PCA 기반 Head Pose Estimation 방법

이경민,인치호,Lee, Kyung-Min,Lin, Chi-Ho 한국인터넷방송통신학회 2021 한국인터넷방송통신학회 논문지 Vol.21 No.6

In this paper, we evaluate Boosted 3-D PCA as a Dataset and evaluate its performance. After that, we will analyze the network features and performance. In this paper, the learning was performed using the 300W-LP data set using the same learning method as Boosted 3-D PCA, and the evaluation was evaluated using the AFLW2000 data set. The results show that the performance is similar to that of the Boosted 3-D PCA paper. This performance result can be learned using the data set of face images freely than the existing Landmark-to-Pose method, so that the poses can be accurately predicted in real-world situations. Since the optimization of the set of key points is not independent, we confirmed the manual that can reduce the computation time. This analysis is expected to be a very important resource for improving the performance of network boosted 3-D PCA or applying it to various application domains. 본 논문에서는 Boosted 3-D PCA 방법을 데이터 세트로 평가하고 성능을 평가한다. 그런 다음 네트워크의 특징과 성능을 분석하겠습니다. 본 논문에서는 Boosted 3-D PCA 학습방법을 사용하여 300W-LP 데이터 학습을 수행했으며 AFLW2000 데이터 세트를 사용하여 평가를 평가했다. 결과는 이 성능 결과는 기존 랜드마크 대 포즈 방법보다 자유롭게 얼굴 이미지의 데이터 세트를 사용하여 학습할 수 있으므로 실제 상황에서 포즈를 정확하게 예측할 수 있다. 키포인트 세트의 최적화는 독립적이지 않기 때문에, 우리는 계산 시간을 줄일 방법을 확인했다. 이 방법은 Boosted 3-D PCA 성능을 향상시키거나 다양한 애플리케이션 도메인에 적용하는 데 매우 중요한 자원이 될 것으로 예상한다

대용량 전력저장용 이차전지 세라믹 소재 개요 및 향후 전망

이경민,윤중락,Lee, Gyeong-Min,Yun, Jung-Rak 한국전기전자재료학회 2013 전기전자재료 Vol.26 No.12

각막굴절교정수술 이후 안압 상승의 위험인자

이경민,김미금,위원량,이진학,Kyoung Min Lee,Mee Kum Kim,Won Ryang Wee,Jin Hak Lee 대한안과학회 2010 대한안과학회지 Vol.51 No.10

Purpose: To investigate changes in intraocular pressure (IOP) after corneal refractive surgery and determine risk factors associated with increased IOP (IIOP). Methods: This retrospective observational study was comprised of 450 eyes of 225 patients, each of whom had corneal refractive surgery in Seoul National University Hospital between January 2004 and January 2008, and were followed for more than one month. IIOP was defined as IOP above 130% of the predicted IOP, adjusted according to corneal thickness and repeated more than twice after postoperative 1 week or after anti-glaucoma medication was needed. Correlation and stratified regression analyses were performed for eyes with myopia and IIOP. Logistic regression analysis was performed to assess risk factors of IIOP and need for medication. Results: IIOP was detected in 22.2%, and anti-glaucoma medication was required in 12.0%, of eyes. The mean IIOP of the medication group was 5.6 ± 3.4 mmHg. Stratified regression analysis showed that the proportion of IIOP did not differ significantly by the degree of myopia. Logistic regression analysis revealed that statistically significant risk factors of IIOP were female gender, preoperative low IOP, and thicker cornea. The statistically significant risk factor of need for medication was the corneal thickness. Conclusions: Thick corneal thickness was found to be a significant risk factor of IIOP after corneal refractive surgery was performed, and IIOP was not affected by the degree of myopia. J Korean Ophthalmol Soc 2010;51(10):1333-1337

황기약침액(黃耆藥鍼液)의 NO, DPPH 소거(消去) 및 IL-4 억제효과(抑制效果)

이경민,서정철,한상원,Lee, Kyung-min,Seo, Jung-chul,Han, Sang-won 대한침구의학회 2003 대한침구의학회지 Vol.20 No.2

Objective : This study was designed fo find out whether Astragali Radix Herbal-Acupuncture Solution(ARHA) can scavenge NO, DPPH and IL-4 or not. Astragali Radix has been clinically used to reforce the depression of immune reponse etc. in Oriental Medicine. Methods : Free radical metabolism seems to occupy a remarkably common position in the mechanisms of ageing and ageing related disease. Oxidative damage to DNA, lipids, proteins and other molecules may contribute to the development of cancer, cardiovascular disease and possibly neurodegenerative disease. The effects of ARHA on NO, DPPH and IL-4 were measured. Results : The followings are the summary of the result; (1) There is a significant scavenging effect of ARHA on NO in 1, $10mg/m{\ell}$ group in after 24hrs. (2) There is no significant scavenging effect of ARHA on DPPH. (3) There is a significant scavenging effect of ARHA on IL-4 in 1, $10,100{\mu}g/m{\ell}$ group. Conclusions : These results suggest that ARHA has significant scavenging effect on NO, IL-4 and not on DPPH. This study shows that ARHA can be used for ageing related disease and further studies are required to investigate the antioxidative effects of it.

대학도서관에서 대학생 독서지도 방안에 관한 연구

이경민,Lee, Kyung-Min 한국도서관정보학회 2012 한국도서관정보학회지 Vol.43 No.4

다양한 멀티미디어와 정보통신 기술의 발달로 인하여 국내 대학도서관들의 도서대출량이 급감하고 있을 뿐만 아니라 대학생들의 독서량도 급감하고 있다. 이에 대학도서관들은 교양학습의 중심으로 교양독서 진흥을 위한 다양한 행사를 진행하고 있지만 대학생들에게 실질적인 도움이 되지 못하고 있다. 이를 해결하기 위하여 현재 국내에서 활발하게 독서행사를 실시하고 있는 4개의 대학도서관을 대상으로 벤치마킹하였다. 결과에 의하면 교양필독서로 추천된 도서는 대학교육시스템 속에서 의무적으로 읽을 수 있는 방안이 적당하고, 도서관 독서행사로는 내적인 동기부여를 할 수 있는 독서토론이 효과적이며, 독서교육에는 글쓰기를 통하여 개인의 직접 경험과 독서 경험을 일체화 시킬 수 있는 방법이 바람직하다. 이를 위해서 대학생들에게 독서지도를 담당할 사서들의 독서력이 필요하다. Because of the development of varieties multimedia and information technology, university students's book reading and university library's book borrowing rate is decreasing. As a center of liberal learning, university libraries have many events for the promotion of reading. But those events do not give practical help for students. In order to solve this problem, researcher benchmarked 4 university libraries that have most active in reading events. The results is below. For reading promotion about the liberal books that was recommended by university, it is suitable to be reading in university education system. Reading discussion is effective for motivation in library reading events. Writing is preferable at reading education by integrating the personal and reading experience. The reading ability of librarians is essential for good reading service in library.

변화관리를 위한 대학도서관의 리더십에 관한 연구

이경민,Lee, Kyung-Min 한국도서관정보학회 2011 한국도서관정보학회지 Vol.42 No.1

인터넷과 디지털 매체의 발달로 오늘날 한국 대학도서관은 사서감축이나 혹은 이용자 감소 등으로 인하여 위기 상황에 직면해 있다. 이를 해결하기 위하여 변화과정에 많은 지식과 경험을 축적하고 있는 기업의 변화관리에 관한 문헌들을 참조하여 문제를 해결하고자 하였다. 대학도서관은 사서들이 공감하는 위기의식을 이끌어 내고 이를 바탕으로 사서들에 의해 비전제시가 이루어지도록 해야 한다. 그러나 비전은 단순히 제시되는 것보다 이를 실천해야 한다. 비전을 실천하기 위해서 관리자와 영향력 있는 일반 사서들이 리더십을 공유하는 것이 현 시점의 대학도서관에서 바람직한 대안이라고 본다. 나아가 사서들을 위한 체계적인 리더십 교육이 필요할 때이다. University libraries in Korea are facing a crisis because of decline of users and librarian reduction from internet development and digital media. To solve this problem, author referred to the literatures on change management of company. Because there are many accumulating knowledge and experiences about company change management. It is necessary to lead the sympathetic sense of crisis by all university librarians. The vision should be made by all librarians' agreement. But the vision practice is more important than developing. In order to practice the vision, it is more useful to share the leadership with general manager and influential librarians in Korea university libraries. Furthermore, systematic leadership training for librarians is needed than ever.

한국인에게 플라세보 이침의 적용이 가능한가? - 단일검맹과 무작위배정법을 통한 플라세보 이침의 효과 -

이경민,이세연,김성웅,하일도,조건호,박히준,정태영,서정철,한상원,Lee, Kyung-min,Lee, Se-yun,Kim, Sung-woong,Ha, Il-do,Cho, Geon-ho,Park, Hi-joon,Jung, Tae-young,Seo, Jung-chul,Han, Sang-won 대한침구의학회 2003 대한침구의학회지 Vol.20 No.2

Objective : This study was designed to find out whether placebo auricular acupuncture is able to be constituted as an appropriate control group for needle insertion to Korean. Methods : We performed a randomized controlled, single-blind study(n=48) comparing subjective evaluations of needles insertion and avoidance of needles insertion. Both ears were needled concurrently, one real acupuncture(needle insertion) and the other placebo acupuncture(avoidance of needle insertion with blunt tip). Subjects then completed a questionnaire rating the intensity of five sensations in each ear, and also attempted to identity which ear received placebo and which ear received real acupuncture. Results : As for the effects of real and placebo acupuncture on each item(Warmth, Fullness, Pain, Activity, Radiating), real acupuncture was significantly warmer, fuller, more painful than placebo acupuncture. In particular, the real acupuncture only in experienced acupuncture recipients was significantly warmer, fuller, more painful than placebo acupuncture. About the ability to differentiate real and placebo acupuncture, 54.2 percent correctly identified which ear received real acupuncture and which ear received placebo acupuncture. However, the ability to differentiate real and placebo acupuncture for naive and experienced acupuncture recipients was not significantly different. Conclusions : Most of the subjects(Korean) identified which ear received placebo and which ear received real acupuncture. We found that this placebo auricular acupuncture is not able to be applied to Korean, in particular for experienced acupuncture recipients. Further study is needed for new placebo auricular acupuncture or racial difference between American.

Oligonucleotide chip를 이용한 홍화자약침액(紅花子藥鍼液)이 간암세포주(肝癌細胞柱)의 유전자(遺傳子) 발현(發顯)에 미치는 영향(影響)

이경민,임성철,정태영,서정철,한상원,Lee, Kyung-min,Lim, Seong-chul,Jung, Tae-young,Seo, Jung-chul,Han, Sang-won 대한침구의학회 2005 대한침구의학회지 Vol.22 No.3

Objective : It has long been known about the osteogenic effect of CTF-HAS on bone tissues. However, it has not been determined the effect of CTF-HAS on cancer cells. The purpose of this study is to screen the CTF-HAS mediated differentially expressed genes in cancer cells such as HepG2 hepatoma cells lines. Oligonucleotide microarray approach were employed to screen the differential expression genes. Methods : CTF-HAS was prepared by boiling and stored at $-70^{\circ}C$ until use. Cells were treated with various concentrations of CTF-HAS(0.1, 0.5, 1.5, 10, $20mg/m{\ell}$) for 24 h. Cytotoxicity was tested by MTT assay. To screen the differentially expressed genes in cancer cells, cells were treated with $1.5mg/m{\ell}$ of CTF-HAS. For oligonucleotide microarray assay, total RNA was used for gene expression analysis using oligonucleotide genechip (Human genome U133 Plus 2.0., Affimatrix Co.). ResuIts : It has no cytotoxic effects on HepG2 cells in all concentrations (0.1, 0.5, 1.5, 10, $20mg/m{\ell}$). More than twofold up-regulated genes were 19 genes. The number of more than twofold down-regulated genes was 13. Discussion : This study showed the screening of CTF-HAS mediated differentially regulated genes using combined approaches of oligonucleotide microarray. The screened genes will be used for the better understanding in therapeutic effect of CTF-HAS on cancer field.