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      • Web기반 교육의 효율성 및 활용에 관한 연구

        이승렬(Lee seung-ryol),윤호군(Yoon ho-gun),정화영(Jeong hwa-young) 한국콘텐츠학회 2003 한국콘텐츠학회 종합학술대회 논문집 Vol.1 No.1

        웹기반 교육은 사용자가 원하는 시간과 장소에서 학습자 스스로 수준별 학습이 가능하며 능동적으로 학습에 참여할 수 있는 장점이 있다. 이를 바탕으로 한 웹 코스웨어는 원거리 학습자들의 학습 욕구를 가능케 했으며 기존의 텍스트, 사운드를 통한 단순한 콘텐츠에서 동영상 이미지를 중심으로 한 멀티미디어 동영상 강의, 하이퍼텍스트로 구성된 인터넷 홈페이지 등 주문형 교육 서비스(EOD : Education On Demand)가 가능해 졌다. 이처럼 현재 많은 분야에서 다양한 방법으로 웹기반 교육콘텐츠를 개발하여 학습에 활용하고 있다. 이에 본 연구에서는 양적으로 팽창하는 웹 코스웨어의 효율성을 분석하고 이를 통하여 보다 질적인 우수성을 포함하는 콘텐츠 활용 방안을 연구하고자 한다.

      • KCI등재

        3D CT를 이용한 비구 컵 주위 골용해 측정 및 임상 결과와의 관련성

        손원용 ( Won Yong Shon ),오종건 ( Jong Gun Oh ),윤호현 ( Ho Hyun Yun ),윤지열 ( Ji Yeol Yoon ),김승주 ( Seung Ju Kim ) 대한고관절학회 2009 Hip and Pelvis Vol.21 No.1

        목적: 골반골 주위에서 발생한 골 용해 크기 및 위치를 측정하고 임상 성적과의 관련성을 알아 보고자 하였다. 대상 및 방법: 무 시멘트형 비구컵을 사용한 인공 고관절 전치환술을 받은 환자 97명(116례)에게 3D CT가 시행되었고, 이중 명확한 골 용해를 가진 40례(31환자)에 대해 연구를 시행하였다. 대상 환자들은 수술 후 6-12주에 방사선 사진을 촬영하였고, 추시 기간이 18개월 이상이며 감염의 과거력이 없었다. 골 용해의 크기 1 cm3미만(A), 1 cm3에서 2 cm3미만(B), 2 cm3에서 3 cm3미만(C), 3 cm3(D) 이상의 4개의 군으로 분류 하였으며, 골 용해의 위치를 전방, 후방, 상방, 하방, 중앙의 5 군으로 분류하였다. 골 용해 크기, 골 용해 위치, 폴리에틸렌 마모와 임상결과(Harris hip score)간의 관련성을 통계학적으로 분석하였다. 결과: 골 용해군의 평균 체적은 3.2 cm3이었으며(A군 14례, B군 11례, C군 4례, D군은 11례) 골 용해 크기와 임상성적간에 통계적으로 유의한 상관관계를 보였다(Rs=-0569). 그러나 골 용해의 위치에 따른 분류 상 전방 18례, 상방 5례, 후방 10례, 하방 33례, 중앙 32례이었으며 골 용해 위치와 임상성적간에 통계적으로 유의한 차이는 없었다(P=0.35). 결론: 골 용해 크기와 임상 성적 사이에는 의미있는 상관 관계가 보였고(Rs=-0569), 특히 3 cm3 이상의 골 용해 군에서는 통계학적으로 유의한 임상성적의 감소가 관찰 되었다(P=0.022). 이는 추 후 골 용해에 대한 치료를 결정하는데 있어 하나의 지침이 될 수 있으리라 사료된다. Purpose: We wanted to measure the size of the osteolysis of the pelvis and to quantify its location and we wanted to assess the correlation of these measurements with the clinical result. Materials and methods: We evaluated 40 hips (31 patients) that showed definitive osteolysis among 116 hips (97 patients) that underwent 3 dimensional CT scanning post-operatively after total hip arthroplasties with using cementless acetabular cups. The inclusion criteria were a follow up duration of more than 18 months and no history of infection. The radiographs were obtained at the 6th to 12th week postoperatively. The size of pelvic osteolysis was divided into 4 groups (less than 1 cm3 (A), between 1 cm3 to 2 cm3 (B), between 2 cm3 to 3 cm3 (C), more than 3 cm3 (D)), and the location of osteolysis was divided into 5 groups (anterior, posterior, superior, inferior and central) The size and location of osteolysis and the wear of the polyethylene were analysed in relation to the clinical outcome, which was assessed using the Harris Hip Score). Results: The average size of the osteolysis was 3.2 cm3 (A 14 cases in group A, B 11 cases in group B, C 4 cases in group C, and D 11 cases in group D). There was significant correlation between the size of the osteolysis and the clinical outcome (Rs=-0569). However, there was no significant correlation between the osteolysis location (Anterior: 18 cases, Superior: 5 cases, Posterior: 10 cases, Inferior: 33 cases and Central: 32 cases) and the clinical outcome (P=0.35). Conclusion: There is a significant correlation between the size of the osteolysis and the Harris Hip Score (Rs=-0569). Especially, a pelvic osteolysis of more than 3 cm3 was found to be correlated with a decreased postoperative HHS (P=0.022). We hope that these results may be useful to help guide the treatment of osteolysis.

      • SCOPUSKCI등재

        만성 림프구성 백혈병이 동반된 소세포폐암

        송준석 ( June Seok Song ),이건화 ( Gun Hwa Lee ),이민규 ( Min Kyu Lee ),김웅준 ( Woong Jun Kim ),이승호 ( Seung Ho Lee ),김상헌 ( Sang Heon Kim ),김태형 ( Tae Hyung Kim ),윤호주 ( Ho Joo Yoon ),신동호 ( Dong Ho Shin ),박성수 ( Sun 대한결핵 및 호흡기학회 2011 Tuberculosis and Respiratory Diseases Vol.71 No.6

        Chronic lymphocytic leukemia (CLL) is the most common type of leukemia occurring in Western nations. In CLL it is well known that the risk of a secondary malignancy is higher than in the normal population. But in Korea, CLL is a rare type of leukemia, so there have been only a few reported cases with a secondary malignancy. CLL is characterized by progressive defects in both cell-mediated and humoral immunity. It is known that defects in the immune system of patients with CLL contribute to the development of a secondary malignancy. We experienced a case of a 71-year-old man who suffered from a chronic cough and was diagnosed with small cell lung cancer coexisting with CLL. Until this case, there was no reported case in Korea of small cell lung cancer coexisting with CLL. We now report a case of small cell lung cancer coexisting with CLL and present a literature review.

      • KCI등재
      • 동종 조혈모세포이식 후 발생한 크립토콕쿠스 척추염 1예

        윤호,임동준,이성수,조유경,이동건,최정현,김유진,민창기,김동욱,박정미,김춘추,신완식 대한감염학회 2001 감염 Vol.33 No.4

        Skeletal cryptococcosis is an uncommon infection. Cryptococcus is a common cause of meningitis and infects 7∼10% of patients with AIDS. As well as AIDS, the infection may be seen in association with leukemia, lymphoma, Hodgkin's disease, sarcoidosis, tuberculosis and diabetes, also in patients on steroid medication. But there is no case report of skeletal cryptococcosis following allogeneic hematopoietic stem cell transplantation. A 40-year-old woman was admitted to the hospital because of low back pain. She had chronic myelogenous leukemia for 2 years and underwent allogeneic hematopoietic stem cell transplantation 8 months ago. She have been treated with steroid and cyclosporine orally because of chronic graft versus host disease. On examination she was afebrile and had posterior lower lumbar tenderness. But, she had no reduced strength of low extremities. Open biopsy was underwent. Histology demonstrated budding, round-to-oval, refractile yeast-like organisms within debris. The results of a lumbar puncture were unremarkable and cerebrospinal fluid culture failed to grow bacteria and yeast. The patient was treated with amphotericin B (1 gram) and AmBisome□ (2.8 gram) over 6 weeks. Three months after cessation of therapy, the patient was doing well.(Korean J Infect Dis 33:298∼301, 2001)

      • On Study Outliers and Influential observations in Regression Model

        Kim,Seung Gu,Yoon,Ho Gun 牧園大學校 1986 論文集 - 牧園大學校 Vol.11 No.-

        최소 자승회귀 모형에서 임의의 관찰치를 除去했을 때 추정모형에 큰 변화가 생기면 이 관찰차를 influential observation이라 부른다. 추정모형 y=Xβ는 y=Hy, 단 H=X(X′X)()¹X′ 로 表示되는 바와 같이 추정치는 관찰치의 X-성분에 의해 크게 영향을 받게 된다. 즉, 매우 큰 residual(e()=y()-y())을 갖는 관찰치가 항상 모형에 큰 영향을 미친다고 볼 수 없으며, 이러한 맥락에서 本稿에서는 例를 통하여 다양한 관점에서 추정모형에 큰 영향을 주는 관찰치를 살펴 보았으며, 새로운 통계량을 제안하여 Cook-통계량과 비교 사용해 보았다.

      • 조혈모세포이식 후 발생한 주폐포자층 폐렴에 대한 고찰

        주지현,최정현,이동건,백지연,윤호,이혜정,김세희,신호진,박윤희,박지영,김유진,신완식,김춘추 대한감염학회 2001 감염 Vol.33 No.4

        Background : Pneumocytitis cainii pneumonia (PCP) can occur in immunocompromised hosts especially such as AIDS or cancer patients. Although recent research had focused on PCP in AIDS patients, few studies have described the clinical presentations of PCP in recipients of stem cell transplantation (SCT). We evaluated the clinical manifestations of PCP in SCT patients admitted at St. Mary's hospital, Seoul, Korea. Methods : The medical records of 17 PCP patients undergoing SCT between Feb. 1998 and Feb. 2000 were reviewed. The diagnosis of PCP was confirmed through the demonstration of Pneumocytitis cainii via either cytology of brochoalveolar lavage (BAL) or histological technique of lung biopsy. CMV disease and CMV infection were confirmed by BAL culture and antigenemia respectively . Results : Seventeen patients were all recipients of allogeneic SCT and 7 of 17 patients were performed non-sibling SCT. Patients presented with symptoms including brief period (4 ∼23 days) of fever (76%), dyspnea (70%), cough (64%), and signs such as rare(58.8%), Sixteen patients (94%) had been receiving immunosuppressive agent such as cyclosporine A (64%) or Fk506 (35%) without PCP prophylaxis. Eleven patients (64%) were treated with corticosteroid with mean dose of 16 mg/day prednisolone and mean duration of 4.6 months after post-SCT period. Twelve patients were co-infected with CMV. Another co-infected miCroorganisms were Pseudomonas aeruginosa, Mycobacterium tuberculosis, herpes simplex virus, parainfluenza virus, Average duration of treatment with trimethoprim-sulfamethoxazole (TMP/SMX) was 21 ±9 days. Four patients died, and three of them were related with PCP. Conclusion : PCP developed frequently in patients who were taking immunosuppressive drug due to graft versus host disease or were not taking TMP/SMX prophylaxis. High risk patients showing fever, cough, or dyspnea should be considered to take early bronchoscopic intervention for detection of PCP. When treat for PCP, it also be considered to the possibility of coinfection such as CMV. (Korean J Infect Dis 33:273∼279, 2001)

      • KCI등재후보

        대학병원 근무 간호사의 교대근무가 심리적 변인들에 미치는 영향

        강형곤,고유경,지영건,김수진,윤호,정우식,김명아,임지영 대한간호행정학회 2005 간호행정학회지 Vol.11 No.1

        This study was conducted to assess the effects of shift-work on psychological factors in university hospital's nurses. Method: The subjects were 276 nurses who have worked in a university hospital and the nurses were questioned with self-reported questionnaire forms. We investigated psychological factors(anxiety, depression, stress and self-esteem), nurses' general characteristics and shift-work. The data was analyzed by using SAS for Windows 9.13. Results: The frequency of nurses with anxiety, depression and high stress were 56.5%, 44.9% and 19.6%, respectively. The mean score of self-esteem was 30.03. Stress was higher in cases of having shift-work. Immediately after doing shift-work, nurses had higher depression and stress, and lower self-esteem scores. After controlling confounding variables, psychological factors affected by shift-work was stress. An upward tendency in anxiety, depression and stress were found in cases of doing shift-work for more than 5 years. Conclusions: It is necessary to develope a program for reducing psychological disturbance at the early times of shift-work and to plan adequate shift-work intervals.

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