단백질 분해효소를 분비하는 Bacillus sp. JH-1의 특성에 관한 연구

윤주희,김한복 호서대학교 중앙도서관 1996 호서대학교 논문집 Vol.4 No.1

Bacillus sp. JH-1 strain isolated from soybean paste produced an alkaline protease. This strain grew well in neutral media, and did not grow in alkaline media. It was identified as Bacillus sp. based on its morphological, physiological and biochemical characteristics. The strain JH-1 was a Gram positive, endospore forming, rod-typed bacterium. The extracellular protease was active within a pH range of 6.0~10.0, and at 10~60°C, and it was optimal at pH 9, and 40°C. The protease was activated by Triton X-100, and β-mercaptoethanol.

Successful Pamidronate Treatment of Osteogenesis Imperfecta Type III Infant with Multiple Fractures

윤주희,백종욱,심은정,황일태 대한소아내분비학회 2012 Annals of Pediatirc Endocrinology & Metabolism Vol.17 No.3

Osteogenesis imperfect (OI) is a generalized connective tissue disorder. We report the female neonate case with OI type III who showed severe bone deformities and fractures in utero. At birth, she showed multiple fractures in the clavicle, rib, femur, and wormian bone in the skull X-ray. We initiated pamidronate disodium infusion 30 mg/m2 in cycles of 3 consecutive days from when she was 4 days old, monthly for the first 3months and every 2 months thereafter without adverse effects.

특별강연 : PCR법을 이용한 HPV detection

윤주희 대한산부인과학회 2014 연수강좌 Vol.51 No.-

아토피 증상 영유아기 자녀를 양육하는 부모의 어려움과 요구

윤주희,배지희 한국생태유아교육학회 2013 생태유아교육연구 Vol.12 No.1

본 연구에서는 아토피 증상이 있는 영유아기 자녀의 부모가 양육 과정에서 경험하는 어려움과 지원에 대한 요구를 알아보기 위하여 아토피 증상 영유아기 자녀를 양육하는 12인의 부모를 대상으로 면접을 실시하였다. 연구결과 아토피 자녀를 양육하는 부모들은 자녀의 가려움증으로 인해 잠을 자지 못하는 고통, 죄책감이나 염려로 인한 심리적 고통, 신뢰할 수 있는 치료 정보의 부족, 아토피 치료로 인한 장기 결석과 교사의 인식 부족, 아토피 관리를 위한 부탁이 잘 수용되지 않음으로 인한 어려움, 유아교육기관에서 제공하는 음식과 관련된 어려움, 그리고 또래관계에서의 어려움을 경험하고 있었다. 둘째, 아토피 증상이 있는 영유아기 자녀를 양육하는 부모들이 원하는 지원에는 의료비 지원, 아토피 관련 부모교육과 심리치료, 아토피 자녀를 믿고 맡길 수 있는 유아교육기관 운영, 유아교사와 유아들을 위한 아토피 관련 교육, 그리고 자녀의 아토피 관리를 위한 가정과 기관의 협조 체계 강화가 포함되었다. This study aimed to identify the difficulties and needs of parents raising young children with atopic dermatitis. In-depth interviews were carried out with 12 parents with such children. The findings of the study indicated that most of the parents were not able to sleep enough in order to care for their children who suffered from severe itching at night time. The feelings of guilt and anxiety about the long-lasting illness were also identified as difficulties. Parents raising young children with atopic dermatitis also experienced difficulties in adopting appropriate medical treatments for their child. They reported that their children were often absent from early childhood centers in order to receive proper medical treatment, and they encountered a lack of understanding about the situation from the teachers. Parents also expressed concerns about their child's peer relationships due to the visible skin irritation. To counter these difficulties, the parents wanted financial support for medical treatments, on-going consultations and psychological therapies for families, and early childhood centers that were supportive of children suffering from atopic dermatitis as well as their families. The parents suggested educational activities aimed at enhancing teachers' and children's understanding of atopic dermatitis, and strengthening the collaboration between families and teachers to reduce the symptoms of the disease.

신규간호사의 정맥주입요법 교육 현황과 교육요구도 분석

윤주희,서민정 병원간호사회 2020 임상간호연구 Vol.26 No.1

Purpose: The purpose of this study is to investigate new nurses’ needs for intravenous infusion therapy training by analyzing the current training status. Methods: This study examined the needs for intravenous infusion therapy training with 159 new nurses. The measurement tool consisted of 93 items developed based on intravenous therapy-related studies, and was evaluated on a 4-point Likert scale. For data analysis, SPSS/WIN 25.0 was used, and frequency, percentage, average, standard deviation, paired t-test, were performed. Results: The demand for intravenous therapy education was analyzed using a questionnaire composed of 8 areas, 16 sub-areas, and 93 items. According to the findings, post-ward placement intravenous therapy education(83.7%) is conducted more often than in preliminary education (72.2%). The demand for intravenous infusion therapy education did not differ significantly in preliminary and post-ward placement education (t=-.89, p=.376). While therapy skills were preferred in preliminary education, there were high demands for education content related to blood transfusion, central venous catheter, and drug use in continuing education. As for preferred teaching methods, lecture (38.2%) and simulation (26.7%) were most answered for preliminary education, while a range of methods were preferred for continuing education including lecture (31.1%), clinical practice (20.6%), preceptor training (19.8%), simulation (16.8%), and self-study (11.6%). Conclusion: For efficient training, it is required to provide different education contents and methods for each stage.

Optimizing Treatment for CIPN Patients

윤주희 대한산부인과학회 2021 대한산부인과학회 학술대회 Vol.107 No.-

부인종양학 : 자궁내막암 수술의 최신 동향

윤주희 대한산부인과학회 2011 연수강좌 Vol.45 No.-

Endometrial cancer is a type of uterine cancer that involves the lining of the uterus (the endometrium). In Korea, endometrial cancer is the recently increasing cancer of the female reproductive system. Fortunately, most women are diagnosed at an early stage (before the cancer has spread outside the uterus), when the disease can usually be cured with surgery alone. The main goal of staging cancer is to determine the extent of the disease. Endometrial cancer also is graded to aid in the evaluation. Most endometrial cancers are staged according to a surgical system approved newly in 2009 by the International Federation of Gynecology and Obstetrics. Factors used to stage the disease include the depth of the tumor, whether the tumor has spread to the cervix and other nearby organs, the cytology of the cancer, whether it has metastasized to the lymph nodes, and the extent to which it has spread to other parts of the body. Endometrial cancer in patients who are rarely unable to undergo surgical evaluation, is sometimes staged using an older, clinical staging system. Treatment options for endometrial cancer can be recommended by stage. Endometrial cancer is often diagnosed when a woman who is having some kind of symptoms take an endometrial biopsy or D&C. Imaging tests, such as ultrasound, CT, MRI and PET-CT scan, may be done to look for signs that the cancer has spread to lymph nodes or tissues outside of the uterus. Even when these tests show no signs of cancer spread, surgery is needed to fully stage the cancer. This operation includes removing the uterus, fallopian tubes, and ovaries (total hysterectomy bilateral salpingo-oophorectomy - TAH with BSO). Lymph nodes from the pelvis and around the aorta are also removed (a pelvic and para-aortic lymph node sampling or dissection [PLND and PALND] ) and examined for cancer spread. Pelvic washings are obtained. If tests done before surgery show signs that the cancer has spread outside of the uterus, a different surgery may be planned. There are some available access options in surgery : laparotomic, laparoscopic, transvagianl and robotic approach. There are some questions in this disease until now ; 1. Reanalysis of previous data based on the new staging system, FIGO 2009; Is new system adequate for staging? 2. The clinical significance of lymph node dissection ; Is there any therapeutic value and/or diagnostic value? What is the adequate extent level in the view of the feasibility, morbidity and clinical outcomes of the para-aortic lymph node dissection? 3. Comparison of robotic, conventional laparoscopic and laparotomic approach in surgical staging ; Is any approach adequate and/or available in any stage? 4. What is the treatment of choice in the far advanced/recurrent endometrial cancer? ; Surgery or conservative management 5. Fertility/ovarian preserving management in endometrial cancer ; Is it adequate? Many questions could be resolved by well-designed randomized controlled trial (RCT).

호스피스ㆍ완화의료 환자와 가족의 이별을 돕는 미술치료사 체험연구

윤주희,김태은 한국미술치료학회 2019 美術治療硏究 Vol.26 No.4

This study aimed to understand the experience of an art therapist who helped a Hospice Patient and his family through death. For this purpose, in-depth interviews were held from August to November 2018, and the main research participant was a hospice palliative care art therapist with four master’s degrees in art therapy. Van Manen’s hermeneutic phenomenological method were tried to derive a total of 5 essential topics and 16 sub-topics. Based on the study of hospice art therapy, the following three results were obtained. First, the Patient and his family members had the opportunity to express their feelings through art therapy in a hospice palliative care setting and experience forgiveness and reconciliation. Second, the hospice patients and their families acknowledged the importance of the patient’s remaining life, and shared meaningful memories for themselves. Third, the art therapist's work with the patient was a valuable gift to the patient's family. The purpose of this study was to make the preparation process to say farewell meaningful for the hospice patient and his family by using art therapy as a preventative healing process for suffering after loss. Through this study, it was found that the art therapist becomes a bridge connecting the patient and the minds of the family, and that the patient becomes a tool to dignify the end of life. In addition, in the hospice palliative care field, the art therapist has significance as the patient's final companion in life. 본 연구의 목적은 호스피스ㆍ완화의료 환자와 가족의 이별을 도운 미술치료사가 어떠한 체험을 하였는지 그 의미와 본질을 알아보고자 한다. 2018년 8월부터 11월까지 심층 면담을 진행하였으며, 연구참여자는 총 4명으로 미술치료 석사학위를 취득한 호스피스ㆍ완화의료 미술치료사이다. van Manen(1990)의 해석학적 현상학 연구를 통해 5개의 본질적 주제와 16개의 하위 주제를 도출하였다. 연구 결과를 토대로 호스피스ㆍ완화의료 환자와 가족의 이별을 도운 미술치료사의 체험에 대한 결론은 다음과 같다. 첫째, 환자와 그의 가족은 호스피스ㆍ완화의료 현장에서 미술치료로 자신의 감정을 표현하였고, 이러한 과정에서 용서와 화해를 경험하기도 하였다. 둘째, 호스피스ㆍ완화의료 환자와 가족은 환자의 임종이 가까워짐을 느낄수록 마지막 시간을 의미 있게 보내고자 하였다. 셋째, 미술치료사가 환자와 함께 제작한 작품은 환자 가족에게 귀한 유품이 되었다. 본 연구는 미술치료를 통해 호스피스ㆍ완화의료 환자와 가족이 경험할 이별을 의미 있게 준비하고, 상실 후 겪을 슬픔의 예방적 치유과정이 되고자 하였다. 본 연구를 통해 미술치료사는 환자와 가족의 마음을 연결하는 다리가 되고, 환자가 존엄하게 생을 마감하기 위한 도구가 된다는 것을 알 수 있었다. 또한, 호스피스ㆍ완화의료 현장에서 미술치료사는 환자의 삶의 마지막 동행자로서 중요한 역할이 됨을 밝힌 것에 의의를 둔다.

Development of reversed-phase HPLC methods for the determination of permaton red in cosmetics

윤주희,박은지,김예진,김규봉,나동희 한국분석과학회 2016 학술대회논문집 Vol.2016 No.11

Mechanical resonance properties of porous graphene membrane; simulation study and proof of concept experiment

윤주희,권민희,신동훈,이상욱 한국물리학회 2021 Current Applied Physics Vol.23 No.-

Mechanical resonance properties of porous graphene resonators were investigated by simulation studies. The finite element method was utilized to design the porous graphene membrane pattern and to calculate the mechanical resonance frequency and quality factor. The changes in the resonance frequency and quality factor were systematically studied by changing the size, number, and relative location of pores on the graphene membrane. Mass loss and carbon-carbon bond break were found to be the main competing parameters for determining its mechanical resonance properties. The correlation between the geometry and the damping effect on the mechanical resonance of graphene was considered by suggesting a model on the damping factor and by calculating the membrane deflections according to the pore location. Based on the simulation results, an optimal porosity and porous geometry were found that gives the maximum resonance frequency and quality factor. Suspended graphene with various number pore structures was experimentally realized, and their mechanical resonance behaviors were measured. The trend of changes in resonance frequency and quality factor according to the number of pores in the experiment was qualitatively agreed with simulation results.