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윤재희 ( Jae Hee Yun ),양선영 ( Sun Young Yang ),김일 ( Il Kim ),홍철호 ( Cheol Ho Hong ),이혜순 ( Hye Soon Lee ),엄완식 ( Wan Sik Uhm ),김태환 ( Tae Hwan Kim ),전재범 ( Jae Bum Jun ),유대현 ( Dae Hyun Yoo ),배상철 ( Sang Cheol B 대한류마티스학회 2003 대한류마티스학회지 Vol.10 No.4
Objective: Although clearly demonstrated in idiopathic thrombocytopenic purpura, Kawasaki disease, the efficacy of intravenous immunoglobulins in the treatment of rheumatic diseases is still being debated. We investigated the effect of high dose intravenous immunoglobulins in selected rheumatic diseases. Methods: Twenty nine patients with rheumatic diseases who had received high dose intravenous immunoglobulins were studied. There were 18 patients with systemic lupus erythematosus (SLE), 8 dermatomyositis/polymyositis (DM/PM) patients, 2 adult onset still`s disease (AOSD) patients and 1 Henoch-schnlein purpura patient. They were treated with high dose intravenous immunoglobulins (each course consisted of 400 mg/kg for 5 days). Each patient received between 1-37 treatment courses. These patients were evaluated both by clinical outcome and by serologic profile that were taken before and after treatment. Results: Clinical improvement was observed in 16 patients out of 29 patients. Nine patients of them could decrease daily prednisolone doses. The clinical manifestations that responded good were: skin rash and ulcer, high fever, vasculitis, hemolytic anemia, thrombocytopenia, myositis. However lupus nephritis and interstitial lung disease did not benefit from the treatment. Conclusion: The high dose intravenous immunoglobulin treatment is good in patients with SLE, DM/PM and AOSD when they are steroid dependent or steroid resistant.
윤재희 ( Jae Hee Yun ),강종명 ( Jong Myung Kang ),김경수 ( Kyung Soo Kim ),김승현 ( Seung Hyun Kim ),김태환 ( Tae Hwan Kim ),박용욱 ( Yong wook Park ),성윤경 ( Yoon Kyoung Sung ),손주현 ( Joo Hyun Sohn ),송병주 ( Byung Joo Song 대한류마티스학회 2004 대한류마티스학회지 Vol.11 No.3
Objective: Few studies have examined the impact of chronic diseases on populations using a comprehensive health-related quality of life (HRQOL) in Korea. We assessed HRQOL of patients with 16 common chronic diseases. Methods: We interviewed patients with chronic diseases (n=980) and healthy control (n=288) using two HRQOL measurements: Korean Medical Outcome Study Short Form-36 (KSF-36) and Korean EuroQol-5 Dimensions (KEQ-5D), and questions on sociodemographic and clinical characteristics. Results: Each illness had a distinctive profile. Among disease groups, the KSF-36 global health score was highest in DM and lowest in fibromyalgia. The KSF-36 physical component summary score was highest in DM and lowest in osteoarthritis. The KSF-36 mental component summary score was highest in hypertension and lowest in fibromyalgia. The KEQ-5D utility score was highest in DM and lowest in fibromyalgia. The KEQ-5D visual analog score was highest in DM and lowest in liver cirrhosis. In correlation analysis, the KSF-36 physical component summary, mental component summary and five domains in KEQ-5D were well correlated with each others. Conclusion: Health related quality of life in Korean patients with chronic disease is lower than healthy control. Patients with hypertension and DM registered the two highest scores in global health but patients with fibromyalgia reported the worst health experience in global health. We can compare the profiles of the groups and determine the relative impact on the patients of the various diseases and these data will provide a baseline of the current health related quality of life of individuals suffering from a variety of conditions.
윤재희(Jae Hee Yun),이상진(Sang Jin Lee) 한국디자인문화학회 2008 한국디자인문화학회지 Vol.14 No.3
The culture has been various and has newly developed to meet the requirements of people throughout history. Table manners of our country was clearly distinguished from the foreign`s, but now, our table manners needs changing to walking in step with globalization. This study is advanced by suggesting personal bowl that is a new improvement direction of the double dipping act-to eat together with a big food bowl-which is the biggest problem in today`s table manners. This study restricts the scope to personal bowl that will be used when our people enjoy eating the soup food such as the pot stew type and develops an idea sketch in the form in parallel with the general and characteristic functions that the personal plate must be equipped with. It is expected that many people will recognize the necessity of our characteristic personal tableware and make the best use of it by developing it as various forms.
파킨슨병 환자의 영양 상태에 따른 식사의 질 및 삶의 질에 관한 연구
윤재희(Yun Jae-Hee),임현정(Lim Hyun-Jung),우미혜(Woo Mi-Hye),안태범(Ahn Tae-Beom),조여원(Choue Roywon) 韓國營養學會 2012 Journal of Nutrition and Health Vol.45 No.3
Assessment regarding the nutritional status of Parkinson's disease (PD) patients is important because their nutritional status influences the outcome of disease. The purpose of this study investigated the dietary habits, dietary quality, and quality of life for Korean PD patients according to their nutritional status. Seventy PD patients were recruited from K University Hospital (KMC IRB#0918-07) from February 2010 to October 2011. To diagnose PD, the United Kingdom Parkinson's Society Brain Bank standards were used by a neurology physician. The participants were interviewed and assessed using various tools, including a general questionnaire, anthropometrics, questionnaires for dietary habits, dietary diversity score (DVS), dietary variety score (DVS), diet quality index-international (DQI-I), beck depression inventory (BDI), the Korean version of mini mental state examination (K-MMSE), and 36-item short-form health survey (SF-36). The results of the study were as follows: 1) Most of the PD patients (69.0%) were at risk of malnutrition, and 8.5% and 22.5% of the subjects were malnourished and well-nourished, respectively. 2) Clinical symptoms (swallowing and chewing difficulties) were obvious, and the quality of diet (DDS, DVS, DQI-I) was low in the malnourished group (p < 0.01). 3) The malnourished group had significantly lower scores regarding SF-36 (quality of life) as well as that of cognitive function (p < 0.05). 4) The nutritional status of PD patients was significantly correlated with their depression (p < 0.05) and quality of life (p < 0.01). These results indicate that appropriate nutritional management will improve the nutritional status and quality of life as well as the cognitive function in Parkinson's disease patients.
그린리모델링 성과 검증 프로세스 제고를 위한 사례 분석 :2020 강원권 공공건축물 그린리모델링을 대상으로
손령빈(Ryeongbin Son),우희찬(Hee Chan Woo),윤재희(Jae Hee Yun),정다인(Da In Jung),임종연(Jongyeon Lim) 대한설비공학회 2022 대한설비공학회 학술발표대회논문집 Vol.2022 No.6
정부는 온실가스 감축을 위해 노후 건축물을 대상으로 그린리모델링을 진행하는 방안을 도입했다. 본 논문은 2020년 공공건축물 그린리모델링 사업대상지 중 강원권에서 수행된 총 81건에 대한 현지 조사 및 에너지 성능평가를 통해 견해를 그린리모델링 성과검증 프로세스 제고의 관점에서 정리한 것이다.
사이클로포스파마이드 치료 후 심한 백혈구감소증을 보인 Cytochrome P450 2A6*1B 변이형을 가진 환자
성상석 ( Sang Seokg Seong ),윤재희 ( Jae Hee Yun ),김은영 ( Eun Young Kim ),신재국 ( Jae Gook Shin ),전재범 ( Jae Bum Jun ),배상철 ( Sang Cheol Bae ) 대한류마티스학회 2007 대한류마티스학회지 Vol.14 No.2
Cyclophosphamide, a prodrug requiring metabolic activation by cytochrome P450 (CYP) enzymes, is used widely for proliferative lupus nephritis and various CYP isoenzymes have been demonstrated to be involved in the bioactivation of cyclophosphamide in humans, including CYP2A6, 2B6, 2C19, 2C9, 3A4, and 3A5. The response or adverse event after intravenous cyclophosphamide pulse therapy in lupus nephritis patient seems to be different for each individual and genetic polymorphism of CYP may explain the difference. Generally, wild types of CYP seem to be more active in the activation of cyclophosphamide than variant types of CYP. Here, we report a case of lupus nephritis with a genotype of CYP2A6*1B who suffered from severe leukopenia after intravenous cyclophosphamide pulse therapy.
그린리모델링 성과 검증 프로세스 제고를 위한 사례 분석 :2020 강원권 공공건축물 그린리모델링을 대상으로
손령빈(Ryeongbin Son),우희찬(Hee Chan Woo),윤재희(Jae Hee Yun),정다인(Da In Jung),임종연(Jongyeon Lim) 대한설비공학회 2022 대한설비공학회 학술발표대회논문집 Vol.2022 No.6
정부는 온실가스 감축을 위해 노후 건축물을 대상으로 그린리모델링을 진행하는 방안을 도입했다. 본 논문은 2020년 공공건축물 그린리모델링 사업대상지 중 강원권에서 수행된 총 81건에 대한 현지 조사 및 에너지 성능평가를 통해 견해를 그린리모델링 성과검증 프로세스 제고의 관점에서 정리한 것이다.