입효산(立效散)의 Methicillin-Resistant Staphylococcus aureus에 대한 항균활성에 관한 연구

윤재홍,최연주,정승현,신길조,Yoon, Jae-Hong,Choi, Yeun-Ju,Jeong, Seung-Hyun,Shin, Gil-Cho 대한한방내과학회 2013 大韓韓方內科學會誌 Vol.34 No.3

Objectives : Methicillin-resistant Staphylococcus aureus (MRSA) has a cephalosporin and beta-lactam antibiotic-resistant strains. MRSA is one of the major pathogens causing hospital infection and the isolation ratio of MRSA has gradually increased. Consequently, increased resistance to antibiotics is causing serious problems in the world. Therefore, there is a need to develop alternative antimicrobial drugs for the treatment of infectious diseases. Methods : The antibacterial activities of Ipyo-san were evaluated against 2 strains of MRSA and 1 standard Methicillin-susceptible staphylococcus aureus (MSSA) strain by using the disc diffusion method, minimal inhibitory concentrations (MIC) assay, colorimetric assay using MTT test, checkerboard dilution test and time-kill assay performed under dark. Results : The MIC of Ipyo-san water extract against S. aureus strains ranged from 1000 to $2,000{\mu}g/ml$, so we confirmed that it had a strong antibacterial effect. Also, the combinations of Ipyo-san water extract and conventional antibiotics exhibited improved inhibition of MRSA with synergy effect. We suggest that Ipyo-san water extract against MRSA has antibacterial activity so it has potential as alternatives to antibiotic agents. For the combination test, we used Triton X-100 (TX) and DCCD for measurement of membrane permeability and inhibitor of ATPase. As a result, antimicrobial activity of Ipyo-san water extract was affected by the cell membrane. Conclusions : We suggest that the Ipyo-san water extract lead the treatment of bacterial infection to solve the resistance and remaining side-effect problems that are the major weak points of traditional antibiotics.

채소류 중 발암성 농약의 위해성 평가

윤재홍,정용,신동천,이종태,Yoon, Jae-Hong,Chung, Yong,Shin, Dong-Chun,Lee, Jong-Tae 대한예방의학회 1999 Journal of Preventive Medicine and Public Health Vol.32 No.2

Objectio ostinato the carcinogenic risks from the ingestion of some carcinogenic pesticides (CPs) in vegetables sampled at a local agricultural product market in Seoul. Methods: After applying a hazard identification step, we selected four pesticides, such as DDT, dieldrin, folpet, and heptachlor epoxide, for this risk assessment. Concentrations of each pesticide were measured from randomly sampled vegetables. In order to estimate the human exposure levels, we combined the concentration of pesticides in the vegetables with consumption rate of those vegetables. Three scenarios were hypothesized for human exposure assessment. Scenario I was the most conservative which supposed the undetected CPs would be the detection limit values. Scenario II was assumed that the undetected CPs would be a half of the detection limit values, and finally scenario III merely considered only values greater than the detection limit values. We finally presented the estimated carcinogenic risks on the basis of the traditional risk assessment procedure suggested by U.S. EPA. Results: Pesticides including DDT, dieldrin, folpet and heptachlor epoxide were detected in 9 samples (6%) in the range of $0.0006\sim0.09ppm$. The daily intake levels of carcinogenic pesticides were estimated in the range of $0.0009\sim0.0079{\mu}g/day$. As we expected, excess cancer risks based on scenario I was also the highest $(1.1\times10^{-8}\sim5.5\times10^{-5})$. Conclusions: We found that the estimated risks from the pesticides we investigated were not serious. We, however, propose that a continuos monitoring is needed to make sure for the protection of public health.

전기로 제강분진에 함유된 금속원소의 휘발거동에 대한 속도론적 연구

윤재홍,윤치현,이명원,Yoon, Jaehong,Yoon, Chihyun,Lee, Myungwon 한국자원리싸이클링학회 2017 資源 리싸이클링 Vol.26 No.3

전기로 제강분진은 고철을 전기로에서 용해하는 과정에서 발생하는 휘발성분들이 공기 중의 산소와 반응하여 산화물형태로 포집된 미세분말로써 다양한 특성을 가지고 있다. 이러한 전기로 제강분진의 효율적인 자원화를 위해서 반응속도론적 기초실험과 Pilot 규모의 생산실험을 병행하여 실시하였다. 그 결과 전기로 제강분진은 다양한 구성성분과 화합물로 구성되어 있었으며 공통적으로 Cl과 알카리 성분이 다량으로 존재함에 따라 자원화를 위한 실제 조업에 큰 악영향을 미치는 화합물의 형성이 예상된다. 휘발거동은 $1100^{\circ}C$ 영역에서 활발히 진행되고 $1250^{\circ}C$ 영역에서는 용융현상이 나타남을 확인할 수 있었다. 이러한 결과는 Pilot규모의 실증테스트의 결과로 얻은 조산화아연과 환원철의 형성거동에서도 동일한 결과를 얻었다. 이러한 결과는 전기로 제강분진의 자원화 플랜트의 설계 및 조업조건 설정에 유용한 기초자료로 활용이 기대된다. Electric arc furnace steelmaking dust has various physicochemical properties as volatile components generated in the melting process of steel scraps in an electric arc furnace, which is captured in oxide form as fine powder by reacting with oxygen in the air. In order to efficiently recycle these electric arc furnace dust, a kinetic basic experiment and a pilot production test were carried out in parallel. As a result, it was found that the electric arc furnace dust contain a large amount of Cl and alkali components, thus it was expected that the compounds have a great adverse effect on the actual operation for the recycling. It was confirmed that the volatilization behavior was progressing actively at $1100^{\circ}C$ and the electric arc furnace dust was melted at $1250^{\circ}C$. These results are the same as a result of pilot test for the formation behavior of zinc oxide and reduced iron. These results should be useful as basic data for designing the recycling plant of the electric arc furnace dust and establishing the operating conditions.

6 시그마와 TQM의 핵심성공요소가 경영성과에 미치는 영향

윤재홍(Yoon, Jae-Hong),이상현(Lee, Sang-Hyun) 동아대학교 경영문제연구소 2008 經營論叢 Vol.29 No.-

Total quality management(TQM) and Six Sigma are widely used by many companies for quality management innovation, but they have realized that there are no big differences between two concepts. This study is about the effects of critical success factors of Six Sigma and TQM on the business performances. In this paper, multiple regression analysis was used to analyse the effects. The results are as follows. First, Six Sigma critical success factors influenced the TQM critical success factors except for process improvement. Second, TQM critical success factors had a considerable impact on the business performances. This study suggested that because TQM key elements such as continuous improvement, CEO leadership, process management and the establishment of mutual trust were all very helpful for quality and customer satisfaction. In conclusion, quality management is the most successful factor to improve the competitive goals within the company.

アメリカのメキシコと ベトナム系25歲の 混血 女性に對する にきび患者治療の 治驗1例 淸胃散, 魚腥草, 鍼の治療が 中心

윤재홍 ( Jaehong Yoon ) 대한한의진단학회 2013 大韓韓醫診斷學會誌 Vol.17 No.3

Objectives This study is report the effect of Asian Medical treatments for acne. Methods 25 years old mixed Hispanic female in California resident patient who was suffering from acne was treated with the Chung-We mix Extract powder, Houttuyniae Herba Extract and comedone extractor. She was taken a picture to compare with before and after treatments. Results Her acne was decreased and global acne grading system by 35 points to 7point improvement on the after treatments. Conclusion This case has the effectiveness with Herbs. According to Asian medicine, the caused of acne is internal problems and the acne is diagnosed as several kind of heats in the internal organ. Further clinical case of acne is needed for better results and to develop the ways of accurate diagnosis.

한국제조기업의 품질전략과 성과측정에 관한 연구

윤재홍(Jae Hong Yoon) 한국경영학회 1994 經營學硏究 Vol.23 No.4

한국제조기업에서 최근 경쟁력향상을 위해 관심을 가지고 중요하게 추진하고 있는 품질전략에 대하여 연구하였다. 먼저 품질전략집단을 구분한 다음 집단별로 성과측정시 지표를 고려하는 정도와 품질개선활동추진에 차이가 있는지 분석하였다. 또한 외부환경의 불확실성이 성과지표를 중요하게 고려하는 정도에 영향을 미치는지 살펴보았고, 품질경영에 중요한 요소의 영향 정도도 살펴보았다. 연구결과 품질전략집단은 세가지로 분류되었고, 이 각각의 집단들이 성과를 측정할 때 지표의 중요도에는 대체적으로 차이가 있었으며, 품질개선활동도 다르게 추진하고 있었다. 외부환경의 불확실성도 일부 성과지표에 영향을 미치고 있었으며, 품질경영에 중요한 요소들의 운영정도도 품질전략수립과 실제성과에 영향을 미쳤다. 연구결과를 활용하면 제조기업의 품질경쟁력향상에 도움이 될 수 있을 것으로 생각된다.

서비스 기업의 운영전략과 성과측정에 관한 연구

윤재홍(Jae Hong Yoon) 한국경영학회 2002 經營學硏究 Vol.31 No.5

The purpose of this research is to find the types of operations strategy existing in Korean service business, and then tries to examine each types of operations strategy differs in terms of the degree of perceived environmental uncertainty and the defree of importance in performance indicators. Empirical findings of this research are as follows. First, the operations strategy types of the Korean service businesses in the sample were grouped into three; service tangibility strategy group, service reliablity strategy group and service product fiexibility strategy group. Second, to find out the differences in the degree of perceived environmental uncertainty, there were the differences in the environmental uncertainty, there were the differences in the environmental dynamism, but not in the environmental complexity among the groups. Third, to find out the differences in the degree of importance competitive factors of performance indicators, there were the differences in the flexibility and innovation indicator factor and service delivery process indicator factor, but not in the service provider indicator factor and cost related indicator factor among the groups. Forth, in order to find out the differences in the financial and competitive performances, there were the differences in those performances among the groups.

택배업에서 BSC 성과지표 관점간의 인과관계분석

윤재홍(Jae-Hong Yoon),김태완(Tæ-Wan Kim) 동아대학교 경영문제연구소 2007 經營論叢 Vol.28 No.-

This study is to explore that the BSC model empirically verified a causal relationship among the main four perspectives and understood what effects on the total system of the performance evaluation, The result of this study examined the facts that the learning and growth perspective significantly effects on the internal process perspective, the internal process perspective effects on the customer perspective, and finally the customer perspective directly effects on the finance perspective. These results of the study is to ascertain whether the analysis of the causal relationships among BSC perspectives can help the heightening of the strategy executive ability of a parcel service company.

중소기업의 지식경영시스템의 사용에 영향을 미치는 요인에 관한 연구

윤재홍(Jae Hong Yoon),박성근(Sung Geon Park),강판식(Pan Sik Kang) 동아대학교 경영문제연구소 2009 經營論叢 Vol.30 No.-

The analysis was as follows. First, top management support was not significantly affected the organization member"s knowledge sharing intention both public and private sectors which result was different from former researchs. Second, self valuation was positively affected the organization member"s knowledge sharing intention both private and public sectors. Third, confidence between colleagues was positively affected the organization member"s knowledge sharing intention both privet and public sectors. Fourth, trust on the management was not positively affected the organization member"s knowledge sharing intention both public and private sectors. Fifth, compensation system was partly positively affected the organization member"s knowledge sharing intention which meant in private sectors supported this hypothesis but not in the public sector. Sixth, knowledge sharing intention was positively affected the usage of knowledge management system both sectors. Seventh, top management support was not positively affected the usage of knowledge management system both sectors. Eighth, compensation system also was not positively affected the usuage of knowledge management system. Finally, compared between public and private sector significant path was different from each other.

ISO 14001 환경시스템 요구사항이 사업성과에 미치는 영향에 관한 탐색적 연구

윤재홍(Yoon, Jae Hong) 동아대학교 경영문제연구소 2010 經營論叢 Vol.31 No.-

This study is to verify the effects of ISO 14001 environmental management system requirements on business performance. Many korean companies faced the needs of environmental management because of the sustainability but they do not meet the needs so far. The one way to meet those needs is to obtain the ISO 14001 EMS certification. Therefore in this study, the research question is that ISO 14001 environmental management system requirements such as environmental policy, planning, implementing and operation, checking and management review will affect the business performance. In order to achieve this goal, the hypotheses were set and questionnaire were gathered and data were analyzed. The results were as follows. First, environmental policy affected positively to the planning and the implementation and operation. Second, planning, implementation and operation affected positively to the checking. Third checking affected positively to the management review. Finally management review affected positively to the business performance. This result shows that companies should obtain ISO 14001 certification to increase business performance and competitiveness in the global market.