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      • SCOPUSKCI등재

        간신티그램상 간크기의 새로운 평가방법

        윤성도,양일권,박석희,박용휘 대한핵의학회 1982 핵의학 분자영상 Vol.16 No.2

        Estimation of liver size is essential in the diagnosis of liver disease, Many approaches have been attempted in evaluation of liver size such as the measurement of length, area and volume. Among these, area and volume measurements are accurate but complicated, so we commonly use formerly introduced various linear measurements, but in scintigraphy one must calculate the actual liver size using rate of reduction, which is time consuming. Because of these reasons, we carried out present study to represent liver size by means of a simple liver measurement like we express the cardiac size by cardiothoracic ratio. Our cases consisted of 100 clinically normal subjects as the normal group and 50 patients suffering from liver disease and diagnosed to have hepatomegaly on abdominal palpation and scintigram at Dept. of Radiology of St. Mary's Hospital, Catholic Medical College during the period of 8 Months from Jan. 1980. We Measured the liver size using 4 linear diameters(Fig. 1). And as the reference measurement, the distance from the right margin of the liver to the left margin of the spleen was measured. We called this $quot;abdominal transverse diameter(ATD)$quot;. The results were as follows; 1) The smallest value was recorded in the midline vertical diameter(MVD). It was 4.2±0.4cm in normal group and 5.0±0.6cm in the hepatomegaly group. 2) The diameter using other methods ranged from 5.6 to 7.2cm in the normal group and from 6.3 to 7.5cm in the hepatomegaly group. 3) There was significant difference in the ratio of each diameter to ATD between the normal and hepatomegaly group(〈0.0l). We called this $quot;hepato-abdominal ratio$quot;. 4) The $quot;hepato-abdominal ratio$quot; using MVD is 0.43±0.06 in the normal group and 0.53±0.07 in the hepatomegaly group. The $quot;hepato-abdominal ratio$quot; of MVD was most significantly different between normal and hepatomegaly group. 5) The tolerance limits(99%) of $quot;hepato-abdominal ratio$quot; using MVD is from 0.41 to 0.45 in the normal group and from 0.51 to 0.55 in the hepatomegaly group. Therefore, by reasons

      • KCI등재후보

        Pregnancy Associated Osteoporosis

        윤성도 대한골다공증학회 2009 Osteoporosis and Sarcopenia Vol.7 No.3

        It is thought that normal pregnancy does not cause osteopenia or osteoporosis in most women. Although there is bone loss during the first 6 months of lactation, subsequent recovery is generally expected. It has been reported that women can develop pregnancy-associated idiopathic osteoporosis during pregnancy or while lactating. The cause of this is controversial, but most authorities believe that pregnancy unmasks a pre-existing bone disease. In more than one-half of pregnant women, no apparent cause for osteoporosis can be identified. Some known causes of pregnancy-associated idiopathic osteoporosis include heparin therapy, prolonged bed rest, and corticosteroid therapy. In a few cases, overt hyperparathyroidism or thyrotoxicosis eventually develops. Bone mass is the main predictor of fractures. Maximum bone-mass accumulation is reached by the end of the second decade, just before the childbearing age. Pregnancy and lactation are associated with considerable changes in calcium homeostasis to meet fetal calcium demands for skeletal calcification. Although renal conservation of calcium is less efficient during pregnancy, the active absorption of calcium by the intestine doubles by 20weeks. In theory, since there is 30~35g of calcium in the full-term neonate, and considering that the maternal skeleton contains 1,000g of calcium, the effect on the mother should be relatively slight. To help understand the effects of pregnancy on bone turnover and osteoporosis, the author has reviewed the some literature and studies have utilized biochemical markers of bone formation, resorption, and bone turnover before, during, and after pregnancy.

      • 닭肝의 Phosphoenolpyruvate Carboxykinase의 時差變動에 관하여

        尹聖道,曺準承 慶北大學校 醫科大學 1975 慶北醫大誌 Vol.16 No.2

        닭肝의 cytoplasmic PEP carboxykinase의 季節 및 日中變動을 調査하고 그 機轉의 一端을 究明하여 다음과 같은 結果를 얻었다. 1. 닭肝의 이 酵素는 季節的인 變動을 나타내었다. enzyme activity는 12月에서 4月까지는 높았고 그 以外 時間에는 낮은 傾向을 보였다. 2. 이 activity는 또한 日中變動을 나타내었으며 아침에는 높고 저녁에는 낮았다. 3. 이 circadian rhythm은 攝食과 關連이 있었다. 卽 攝食時間을 變更시키면 리듬의 時期가 變動하였으며, 絶食시키면 circadian decrease가, glucose를 주면 circadian increase가 沮止되었다. 4. 이 酵素의 circadin increase는 actinomycin D에 의해서 抑制되었다. This sudy is to observe the circadian variation of chicken liver phosphonenolpyruvate carboxykinase(EC 4.1.1.32) activity and to analyse the influence of fasting, actinomyciin D, and glucose. The results obtained were summerized as follows; 1. The enzyme activity generally exhibited annual rhythmic variation with the high activity in the cold season (Dec.-Apr.) and the low activity in the hot season(May-Nov.), though the ranges of the activity were broad. 2. The enzyme also showed a diurnal variation with a crest at 0800 and trought at 2000, though the amplitude varied with the season. 3. The circadian rhythm of the enzyme activity varied in reversed phase with fasting or changes of feeding time. Cirdadian increase of the enzyme activity was inhibtied by actinomycin D and glucose.

      • KCI등재

        행정중심복합도시 및 혁신도시 건설이 실업비용에 미치는 영향

        윤성도,이성우 한국지역학회 2007 지역연구 Vol.23 No.3

        The present study investigates the impact of the construction of a multifuctional administrative city and innovative cities on unemployment cost. Along with a spatial econometrics model(GWR: Geographically Weighted Regression) that is free from spatial selection bias, we construct a methodology to estimate the aggregate costs caused by the construction of the multifunctional administrative city and the relocation of the 179 public agencies. Utilizing the 2005 City and County data from the National Statistical Office, we construct a model to calculate hypothetical employment opportunities for the destined areas of the public agencies. The present study found that the total cost per annum caused by the relocations is in between 27billion Won to 47 billion Won for the capital region and the benefit for the rest of the area is far less than those for the capital region. The present study concludes that while there are some positive effects due to the relocation policies, the policies aimed at relocating people and jobs from the capital region mainly targeting the public agencies are not much effective than expected. The present study expresses concerns on excessive drive of balanced development policy by the incumbent administration and recommends policies focusing primarily on the objective of fostering national productivity growth. 본 연구에서는 행정중심복합도시 및 혁신도시의 건설에 따른 사회적 편익에 대해 주로 규범적 논의를 바탕으로 진행되고 있는 현재의 논의를 인구이동 효과에 따른 노동시장에서의 편익 및 실업비용의 측면에서 고찰하였다. 이를 위해 현재 논의되고 있는 행정중심복합도시 및 혁신도시의 내용을 바탕으로 작성된 시나리오에 따른 사회적 비용을 계산하였다. 2000년 인구및주택총조사 2% 표본과 시군구의 단위의 집계자료에 대해 공간적 종속성 문제를 유발하지 않는 GWR 모형을 사용하여 분석하였다. 행정중심복합도시 및 혁신도시의 건설에 대한 사회적 발생 비용을 금액가치로 환산하여 구체적 논거를 제시할 수 있다는 의의를 가진 본 연구의 결과는 다음의 시사점을 가진다. 첫째, 행정중심복합도시 및 혁신도시 건설에 따른 균형 있는 발전의 효과는 고용기회 증대를 위한 다양한 노력이 병행될 때 의미가 있다. 둘째, 수도권과 충청권은 지리적으로 상당히 가까운 거리에 위치하며 수도권에 자본이 상대적으로 집중되어 있는 상태이므로 수도권과 충청권의 연담도시화 가능성에 대한 고려가 필요하다. 이러한 시사점은 행정중심복합도시 및 혁신도시 건설의 비수혜지역인 수도권에 대한 배려가 있어야 한다는 논의로 귀결될 수 있으며 또한, 재정투자에 의한 추가적인 효과를 고려한 해석이 필요할 것이다. 지방분권과 국토의 균형 있는 발전에 대한 사회적 요구는 향후 지속적으로 증대할 것으로 예상되며 특히 성장의 논의와 결부된 행정중심복합도시 및 혁신도시의 건설 논의는 더욱 다양한 사회적 요구와 압력에 직면할 것이다. 따라서 향후 심층적이고 복합적인 논의를 통해 이들 해당 도시의 타당성에 대한 종합적인 접근이 보다 발전적인 방향으로 진행되어야 할 것이다.

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