내전형 연축성 발성장애 환자의 보툴리눔 독소-A 주입술 전후의 음성특성 비교

윤보람,김향희,최예린,최홍식 대한이비인후과학회 2011 대한이비인후과학회지 두경부외과학 Vol.54 No.2

Background and Objectives Botulinum toxin type A (BTX-A) injection is well known for its effectiveness in the treatment of “Spasmodic dysphonia”. However, studies on the efficacy of BTX-A injection have not been attempted in Korea. Therefore, this study was carried out to investigate the effects of BTX-A. Subjects and Method The study examined 12 female patients with ‘adductor spasmodic dysphonia’. Objective assesments included aerodynamic analysis and electoroglottography (EGG) of each patient before and after BTX-A. Subjective assessments included using the Korean-version of Voice Handicap Index-30 (KVHI-30) and a patient self-rating scale. Results Aerodynamic analysis revealed that only maximum phonation time (MPT) was significantly shortened after the injection of BTX-A (p<0.05). In the EGG, the mean frequ-ency distribution was significantly increased, while the mean amplitude and the mean clos-ed quotient distribution were significantly decreased (p<0.05). The KVHI-30 and patient self-rating scale scores were significantly decreased (p<0.01) as well, demonstrating the effects of BTX-A on the quality of life. Conclusion Our results show the effects of BTX-A objectively by comparing voice characteristics, which were measured through EGG before and after BTX-A injection, as well as by determining aerodynamic characteristics. The subjective self-assessment on the quality of life is significant as it may serve as a clinically relevant measure. This study may be helpful in elucidating treatment efficacy of BTX-A in many ways.

공간정보 콘텐츠의 현황 및 새로운 거리 수준 콘텐츠

윤보람,최경아,이임평 대한공간정보학회 2014 Spatial Information Research Vol.22 No.6

공간정보를 기반으로 다양한 주제의 매쉬업(mash-up)이 활발해지면서 공간정보 콘텐츠의 품질과 활용성이 높아지고 있다. 항공 수준에서 시작해서 거리 수준의 실외와 실내 공간까지도 실제처럼 표현한 공간정보 콘텐츠들이 등장하였다. 그럼에도 불구하고 거리 수준의 공간정보 콘텐츠를 기반으로 한 매쉬업 사례는 상당히 미진한 상황이다. 본 연구에서는 거리 수준 콘텐츠의 활성화를 위해 기존 거리 수준의 공간정보 콘텐츠가 가진 한계를 도출하고, 이를 극복하기 위한 방안을 모색하고자 한다. 기존의 공간정보 콘텐츠를 공간적 범주와 표현 방법에 따라 분류하여 각 특성에 따라 현황을 분석하고, 이를 통해 기존 거리 수준 공간정보 콘텐츠의 한계를 도출한다. 나아가 기존 거리 수준 콘텐츠의 한계를 극복하기 위한 방안으로 ‘뉴미디어 공간정보 콘텐츠’를 제안한다. ‘뉴미디어 공간정보 콘텐츠’는 콘텐츠 내에서 객체의 3차원 지상 좌표를 결정할 수 있고 그 좌표를 매개로 데이터베이스와 유기적으로 연동될 수 있다. 지상의 절대 좌표를 참조 키로 하는 ‘뉴미디어 공간정보 콘텐츠’는 다양한 정보와의 정교하고 유기적인 연동을 실현하고, 이를 통해 거리 수준 콘텐츠의 활성화에 기여할 것이다. The high popularity of geo-referenced mash-up improves the quality and availability of geo-referenced contents. Such contents which accurately represent the real world in street level as well as in aerial level have appeared. Despite the advent of geo-referenced contents of street level, it is still hardly used for mash-up. In this study, we thus find out its obstacles to spatial mash-up and solutions to overcome them to activate the mash-up based on street level contents. By analyzing the current geo-referenced content with respect to its spatial scope and the way of representation, we draw the limitations of current street level contents. Furthermore, we propose the ‘new media geo-referenced content’ as a solution to overcome those limitations. With ‘new media geo-referenced content’, it is able to determine the 3D coordinates of given object in real world. Using those coordinates, database linkage can be more closer, flexible and organic. Such ‘new media geo-referenced content’ can contribute to activation of geo-referenced contents in street level and its mash-up.

Covariance Fitting of Highly-correlated Data in Lattice QCD

윤보람,Yong-Chull Jang,Chulwoo Jung,이원종 한국물리학회 2013 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.63 No.2

We address a frequently-asked question on the covariance fitting of highly-correlated data such as our BK data based on the SU(2) staggered chiral perturbation theory. Basically, the essence of the problem is that we do not have a fitting function accurate enough to fit extremely precise data. When eigenvalues of the covariance matrix are small, even a tiny error in the fitting function yields a large chi-square value and spoils the fitting procedure. We have applied a number of prescriptions available in the market, such as the cut-off method, modified covariance matrix method,and Bayesian method. We also propose a brand new method, the eigenmode shift (ES) method,which allows a full covariance fitting without modifying the covariance matrix at all. We provide a pedagogical example of data analysis in which the cut-off method manifestly fails in fitting, but the rest work well. In our case of the BK fitting, the diagonal approximation, the cut-off method,the ES method, and the Bayesian method work reasonably well in an engineering sense. However,interpreting the meaning of χ2 is easier in the case of the ES method and the Bayesian method in a theoretical sense aesthetically. Hence, the ES method can be a useful alternative optional tool to check the systematic error caused by the covariance fitting procedure.

공간정보 콘텐츠의 현황 및 새로운 거리 수준 콘텐츠

윤보람,최경아,이임평,Yoon, Bo Ram,Choi, Kyoung Ah,Lee, Im Pyeong 한국공간정보학회 2014 한국공간정보학회지 Vol.22 No.6

공간정보를 기반으로 다양한 주제의 매쉬업(mash-up)이 활발해지면서 공간정보 콘텐츠의 품질과 활용성이 높아지고 있다. 항공 수준에서 시작해서 거리 수준의 실외와 실내 공간까지도 실제처럼 표현한 공간정보 콘텐츠들이 등장하였다. 그럼에도 불구하고 거리 수준의 공간정보 콘텐츠를 기반으로 한 매쉬업 사례는 상당히 미진한 상황이다. 본 연구에서는 거리 수준 콘텐츠의 활성화를 위해 기존 거리 수준의 공간정보 콘텐츠가 가진 한계를 도출하고, 이를 극복하기 위한 방안을 모색하고자 한다. 기존의 공간정보 콘텐츠를 공간적 범주와 표현 방법에 따라 분류하여 각 특성에 따라 현황을 분석하고, 이를 통해 기존 거리 수준 공간정보 콘텐츠의 한계를 도출한다. 나아가 기존 거리 수준 콘텐츠의 한계를 극복하기 위한 방안으로 '뉴미디어 공간정보 콘텐츠'를 제안한다. '뉴미디어 공간정보 콘텐츠'는 콘텐츠 내에서 객체의 3차원 지상 좌표를 결정할 수 있고 그 좌표를 매개로 데이터베이스와 유기적으로 연동될 수 있다. 지상의 절대 좌표를 참조 키로 하는 '뉴미디어 공간정보 콘텐츠'는 다양한 정보와의 정교하고 유기적인 연동을 실현하고, 이를 통해 거리수준 콘텐츠의 활성화에 기여할 것이다. The high popularity of geo-referenced mash-up improves the quality and availability of geo-referenced contents. Such contents which accurately represent the real world in street level as well as in aerial level have appeared. Despite the advent of geo-referenced contents of street level, it is still hardly used for mash-up. In this study, we thus find out its obstacles to spatial mash-up and solutions to overcome them to activate the mash-up based on street level contents. By analyzing the current geo-referenced content with respect to its spatial scope and the way of representation, we draw the limitations of current street level contents. Furthermore, we propose the 'new media geo-referenced content' as a solution to overcome those limitations. With 'new media geo-referenced content', it is able to determine the 3D coordinates of given object in real world. Using those coordinates, database linkage can be more closer, flexible and organic. Such 'new media geo-referenced content' can contribute to activation of geo-referenced contents in street level and its mash-up.

핀부트 홀 직경 축소와 브레이크 래틀노이즈의 상관 관계 분석

윤보람,전경훈,김용희,변문환 한국자동차공학회 2023 한국 자동차공학회논문집 Vol.31 No.10

Caliper rattle noise is mostly caused by vibrations applied to the wheel when the vehicle drives on an unpaved road or a paved road with continuous steps. This can be attributed to loosely fitted components, such as rubber or spring in the caliper. In this paper, we studied the relationship between reducing the size of the pin-boot hole and the brake rattle noise of a two-piston floating caliper. After analyzing the sound sources of the rattle noise, we controlled the tightening force of the pin-boot to improve rattle noise characteristics. This was achieved by reducing the diameter of the pin-boot seating hole in the torque member. The results of our study showed a high correlation between the reduction of the pin-boot seating hole and improvement in rattle noise, as the caliper body and the torque member can vibrate under a more integrated condition. However, as an adverse effect, caliper sliding resistance may increase, leading to high drag and accelerating pad wear. Thus, we are proposing an optimal improvement design range after considering the trade-off relationship between caliper rattle noise and sliding resistance.

여름방학 중 결식 아동에게 제공된 도시락 식단의 식품 구성 평가

윤보람,권수연,윤지현 동아시아식생활학회 2010 동아시아식생활학회 학술발표대회논문집 Vol.2010 No.11

[Issue] 육체노동 연한 65세 상향

윤보람 연합뉴스 동북아센터 2019 마이더스 Vol.2019 No.3

Impact of Culinary and Nutrition Course on Cooking Attitude, Cooking Skills andFood Consumption for College Students

윤보람,전경열 (사)한국조리학회 2020 한국조리학회지 Vol.26 No.5

This study examined the impact of culinary and nutrition education on cooking attitude, cooking skills and dietary pattern for college students. A one-group, pre- and post-test design was employed to measure the changes in cooking behavior and eating behavior. A total of thirty-four college students, ages 18 to 24, participated in the study. For analysis, change scores in cooking attitude and cooking skills were calculated from the difference between pre- and post-scores for each student. In order to assess the impact of the culinary and nutrition class on consumption in fruits and vegetables between pre-, and post-test, a paired t-test was used. The results showed that there were significant improvements in favorable attitude toward cooking and cooking skills between pre -and post-tests. The study revealed that participants significantly increased consumption of fruits and vegetables after the course. The study suggests that the culinary and nutrition class is effective to enhance college students’ cooking attitude and skills and to promote consumption of fruits and vegetables. The results of the current study could offer an empirical evidence for implementation of public policies in the contexts of a university campus. Furthermore, this paper discusses the theoretical and practical implications of the findings and future research ideas.

전기방사 나노섬유처리소재와 상용 투습방수소재의 역학적 특성 비교

윤보람,이승신 한국의류학회 2010 한국의류학회 학술대회논문집 Vol.2010 No.-

Diversity and physiological properties of soil actinobacteria in Ulleung Island

윤보람,노수권,김승범,Yun, Bo-Ram,Roh, Su Gwon,Kim, Seung Bum The Microbiological Society of Korea 2017 미생물학회지 Vol.53 No.4

본 연구에서는 경상북도 울릉군에서 분리한 토양 방선균에 대해 생리학적 특징과 다양성에 대해 연구하였다. ULS1 및 ULS2로 명명한 2개의 토양 시료를 채취하여 다양한 배지에 배양하여 분리하였으며, 평균 생균수는 ULS1 토양은 $1.28{\times}10^7CFU/g$, ULS2 토양은 $2.05{\times}10^7CFU/g$였다. 16S rRNA 유전자에 기반한 염기서열 분석 결과, 총 9개의 속에서 34개의 균주가 분리되었으며 해당 속은 Streptomyces (16 균주), Isoptericola (5 균주), Rhodococcus (4 균주), Agromyces (3 균주), Micrococcus (2 균주), Arthrobacter (1 균주), Williamsia (1 균주), Microbacterium (1 균주) 및 Oerskovia (1 균주)에 속하는 것을 알 수 있었다. 다양한 효소활성과 식물 생장 촉진 활성 측정 결과, 전체의 58.8%가 단백질 분해 활성을, 79.4%가 Tween 80 분해 활성을, 그리고 61.8%가 DNA 분해 활성을 각각 가지는 것으로 나타났다. Oerskovia, Williamsia, Isoptericola 및 Streptomyces 속에 속하는 분리주들로부터 인을 가용화시키는 능력을 확인할 수 있었으며, Agromyces, Oerskovia, Micrococcus, Rhodococcus, Streptomyces 및 Isoptericola 속에 속하는 분리주들은 식물호르몬인 3-indole-acetic acid (IAA)를 생산하는 것을 확인할 수 있었다. Streptomyces 속에 속하는 분리주들은 Candida albicans 뿐만 아니라 Staphylococcus aureus와 Bacillus subtilis에 항생활성을 나타내었다. 본 연구는 독특한 생태계를 구성하는 울릉도 지역의 토양 방선균 다양성 및 생리 활성에 대한 최초의 연구로서 의미를 가지며, 새로운 유용 생리 활성 물질의 좋은 원천이 될 것이라 사료된다. Actinobacteria tolerating extreme conditions can be a rich source of bioactive compounds and enzymes. In this study filamentous actinobacteria were isolated from soils of Ulleung Island, and their physiological properties were examined. Soil samples were collected, serially diluted and spread on various agar media. The average viable counts of total bacteria were $1.28{\times}10^7CFU/g$ for soil sample 1 (ULS1) and $2.05{\times}10^7CFU/g$ for soil sample 2 (ULS2). As a result, 34 strains of actinobacteria were isolated and assigned to the genera Streptomyces (16 strains), Isoptericola (5 strains), Rhodococcus (4 strains), Agromyces (3 strains), Micrococcus (2 strains), Arthrobacter (1 strain), Williamsia (1 strain), Microbacterium (1 strain), and Oerskovia (1 strain) based on 16S rRNA gene sequence analysis. Enzyme activity and plant growth promoting potential were tested for representative isolates. Multiple strains of Streptomyces degraded starch, casein and Tween 80. As for plant growth promoting potential, strains of Oerskovia, Williamsia, Isoptericola, and Streptomyces solubilized phosphate, and those of Agromyces, Oerskovia, Micrococcus, Rhodococcus, Streptomyces, and Isoptericola produced 3-indole-acetic acid (IAA), respectively. Selected strains of Streptomyces exhibited strong antagonistic activity against Staphylococcus aureus and Bacillus subtilis as well as Candida albicans. This study confirms that actinobacteria from Ulleung Island can be a good source of novel bioactive compounds.