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Supported lipid membrane platform technology for anti-infective applications
윤보경,문수지,( Joshua A. Jackman ) 한국공업화학회 2020 한국공업화학회 연구논문 초록집 Vol.2020 No.-
We demonstrate that adding mixtures of lauric acid (LA) and glycerol monolaurate (GML) - two of the most biologically active antimicrobial fatty acids and monoglycerides - to a supported lipid bilayer platform triggers concurrent tubule and bud formation, which unexpectedly results in synergistic phospholipid membrane remodeling that far exceeds the effects of GML or LA alone. The most pronounced effects occurred with equimolar concentrations of GML and LA in the micellar state, highlighting that synergistic membrane disruption and an inability to relieve membrane strains. These findings offer a new model to explain how fatty acid and monoglyceride interactions can trigger phospholipid membrane remodeling events relevant to various biophysical and biological systems.
尹寶卿 한국중국소설학회 2011 中國小說論叢 Vol.33 No.-
中国古典小说从朝鲜王朝初期正式传入韩国后广泛传播。 朝鲜时期(1392至1910年)与中国明清两代(1368年至1911年)在时间上大致重合, 在中国这一时期正是中国古典小说, 尤其是通俗小说的繁荣时期。 在壬辰倭乱(1592‐1598)前后, 中国通俗小说大量传入朝鲜, 读者层也随之扩大。 在朝鲜时期, 读者阅读中国小说主要是汉文原本和韩文译本。 朝鲜在1445年世宗大王创造训民正音后, 大量的中国小说翻译成韩文, 但朝鲜王朝的文人士大夫大部分长期以来以汉文作为表达工具, 他们阅读文言小说的历史由来已久。 因此他们阅读中国小说主要是汉文原本 , 或者为阅读时正确理解汉文句子的意思在汉文句子中加悬吐。 韩国在汉文翻译的方式中, 具有代表性的是口诀与悬吐, 所以中国小说翻译也采用了这种方式。 口诀是从韩国三国时代口头流传下来的, 但现在能看到的口诀资料, 无论是汉文口诀还是韩文口诀, 都是15世纪以后所创造的。 有关使用口诀和吐等词汇的最早纪录在15世纪的世宗实录及初期谚解本记录中能看到。 口诀指在汉文句子中当停顿的地方, 加一个韩文的助词或终结性语尾词, 其作用是帮助韩国人阅读时断句和理解文意, 这是一种汉文及韩文的特征相联接的韩国独有的翻译方式。 口诀种类可分为三种, 有汉字口诀、 助记号口诀、 韩字口诀等。 在朝鲜谚解书中, 有的是由口诀文和韩文译文构成, 这种译本体例是首先根据汉文原本的文意在所有汉文句子中加悬吐, 然后参考悬吐把汉文翻译成韩文的, 其中口诀对正确理解汉文句子的意思发挥关键性作用。 在朝鲜时期的小说大体可分为汉文小说和韩文小说。 其中在汉文句子中加悬吐的悬吐本汉文小说是从朝鲜时期开始出现, 但其数量不多。 悬吐本汉文小说到近代才集中出现。 在悬吐本汉文小说中还有中国古典小说, 包括《諺吐三國志》、 《懸吐三國志》、 《註解西廂記》、 《懸吐註解西廂記》、 《諺文懸吐剪燈新話》等, 这些作品都是当时备受读者欢迎。 本论文先从书志学方面对近代韩国(朝鲜末期至日本殖民统治时期)刊行的悬吐本汉文小说进行考证, 还对悬吐本中国小说的版本、 悬吐方式和特征等进行考证。 笔者相信这一定有助于研究中国古典小说在韩国的传入、 接受、 传播及翻译的历史。
또래와의 수학적 의사소통이 학습부진학생의 수학 학업성취도와 자기효능감에 미치는 영향
윤보경,김수연 한국학습장애학회 2011 학습장애연구 Vol.8 No.1
The present study was conducted to examine the effect of underachievers’ mathematical communication with peers on their mathematical achievement and self-efficiency. Mathematical communication with peers can be defined as mathematical knowledge or their own thoughts such as mathematical concepts, problem solving strategies to talk to peers. Sixteen mathematics underachievers selected from the fifth grade at an elementary school were split into two groups: one was an experimental group, and the other was a control group. A total of fourteen instruction sessions were given to each group, and addition and subtraction of fractions in the number-operation unit were taught in the sessions. Mathematical communication with peers was emphasized in the experimental group, while, in the control group, mathematical communication was conducted between the teacher and students. The results of the study are as follows. First, there was no significant difference between the experimental group and the control group in relation with mathematical achievement; however, the students performed better in the post test compared to the pre test. The experimental group demonstrated a significant increase in the sentence-type questions and a significant decrease in the no-response reaction. It can be explained through the fact that mathematics underachievers in the experimental group improved mathematical communicative competence through intervention. Second, the self-efficiency score of the experimental group showed a significant progression compared to the control group. Discussion on mathematics underachievers' mathematical communicative competence was also presented. 본 연구는 또래와의 수학적 의사소통이 학습부진학생들의 수학 학업성취도와 자기효능감에 미치는 영향을 알아보았다. 또래와의 수학적 의사소통이란 수학적 개념, 문제 푸는 전략 등의 수학 지식이나 자신의 생각을 또래에게 말하고 듣는 활동을 의미한다. 초등학교 5학년 수학 학습부진학생 16명을 실험집단과 통제집단으로 각 8명씩 구성하여 총 14회기 동안 분수 연산 영역을 지도하였다. 실험집단은 또래와의 수학적 의사소통이 강화된 중재를 실시하고, 통제집단은 교사-학생 간 의사소통을 통한 수업을 하였다. 실험집단 수학 학습부진학생들의 의사소통 능력이 향상되어, 수학적 언어를 사용하여 또래와 말을 하고 듣게 되었다. 연구 결과 첫째, 실험집단의 수와 연산 성취도는 통제집단과의 유의한 차이는 나타나지 않았으나, 사전에 비해 사후 검사에서 유의하게 향상되었다. 구체적으로 문장제 해결 능력은 실험집단이 통제집단에 비해 유의한 향상을 보였다. 문제에 어떠한 반응도 하지 않은 무응답 반응도 실험집단이 통제집단에 비해 중재 이후 유의하게 감소하였다. 이는 실험집단 수학 학습부진학생들이 중재를 통해 수학적 언어를 사용하여 또래와 말을 하고 듣게 되는 등의 의사소통 능력이 향상되었기 때문인 것으로 볼 수 있다. 둘째, 실험집단의 자기효능감 점수는 통제집단에 비해 유의하게 향상되었다. 수학 학습부진학생들의 수학적 의사소통 능력에 대한 논의가 이루어졌다.
관객 다시 만나기 : 비대면 공연참여 예술가에 관한 실행연구
윤보경,장웅조 한국무용학회 2021 한국무용학회지 Vol.20 No.4
코로나19의 재난 상황에서 많은 예술가들이 비대면 공연으로의 전환을 시도하고 있다. 본 연구는 집합 제한으 로 존폐위기에 놓여있는 공연시장에서 비대면 공연이 관객을 만나기 위한 창구로서 가능할 것인가에 대한 논 의에서 출발하였다. 비대면 무관중 공연을 처음 경험하는 현대무용가 10인에 대한 실행연구를 진행하여, 연구- 실행-반성-재인식의 단계를 거치며 예술가가 관객과의 관계에 대한 의미를 반추해가는 과정을 추적하고 분석하 였다. 예술성 발현에 대한 의문을 가졌으나 사회적 대안으로 비대면 공연을 받아들인 참여자들은 몇몇 제약에 도 불구하고 예술적 가치와 영감 그리고 자신에 대한 성찰을 충분히 투영시키는 창조적 성과를 보였다. 참여자 들은 새로운 미디어에 적응하며 자발적으로 자신의 공연을 재설계하고 있음을 관찰할 수 있었다. 또한 개개인 의 독특한 표현과 접근을 상황에 맞게 추구해가는 스스로에 위안을 받으며 자존감과 존재감을 회복할 수 있었 다. 이는 새로운 방법을 시도할 수 있는 용기와 열정 회복으로 이어져 적정기술(appropriate technology)을 적 극 활용하여 관객만나기가 가능하다는 긍정적 인식의 변화를 보여주었다. 결과적으로 비대면 공연의 확산은 공 연의 본질과 그 예술성을 침해할 것이라는 부정적 인식을 넘어서 예술가들의 자기 각성을 이끌어내는 터닝포 인트로 작용하였고, 예술가들의 창작적 지평을 넓히는 계기로 작용함을 확인하였다. In the wake of the Covid19 pandemic, many artists are attempting to transition to non-face-to-face performances. This study was inspired by discussions on meeting audiences in non-face to face virtual venues and explores whether online performances offer a solution to the existential crisis in the performative arts market. We worked with ten modern dancers who are engaged in non-face-to-face performance to track and analyze their relationship with audiences. The participants questioned the meaning and expression of their artistry in the non-traditional, non-face-to-face mode the pandemic has forced them to adopt but came to accept it as they found new opportunities to reach audiences that compensated for the limitations. They were able to creatively leverage the new restrictions to achieve creative results that reflected their artistic values, inspiration, and self-reflection. Participants found themselves adapting to the new media by redesigning their performances to meet audiences by actively utilizing appropriate technology. Thus, these artists found that, far from infringing on the nature and artistry of their performances, the non-face-to-face mode offered an opportunity for enhanced artistic self-awareness and a broadening of their creative horizons.
전략적 커플링과 브랜드 오리지네이션의 교차점: 충북 지역 소주 브랜드 기업의 사례
윤보경,이재열 한국도시지리학회 2023 한국도시지리학회지 Vol.26 No.2
This article is about a biography of a localized soju brand-name manufacturer Chungbuk Soju, which has been acquired by a Korean chaebol Lotte in 2011. The story is centered on the challenges posed on the brand’s locally embedded origination, resulting from deregulation, corporate merger, and resultant spatial reorganization of the company. This study is expected to fill an empirical and analytical gap in the research of brand geographies, which have failed to pay deserved attention to the dialectic relationship between brands and corporate reorganization in any spatial sense. Empirical examination is focused in the beginning on industry-wide production networks in soju manufacturing business, with particular attention to input, output, and process standardization. Then, the evolution process of the Chungbuk Soju brand’s origination is examined in relation to the company’s strategic coupling. It is found that the brand’s resurgence and regeneration in the 2000s have become unable to sustain in the 2010s. For vertically integrated internal coordination within the corporate organization of Lotte and weakened capacity of extrafirm bargaining have caused disruption in the brand’s geographical association and origination. These empirical findings call for reflexive rethinking and reworking to both the theory of global production network and the conception of brand origination.
윤보경,Tae Gyu Oh,부성현,서경진,권세환,Ji Yoon Lee,Yeumin Kim,김재우,Hyo-Suk Ahn,Sungsoon Fang 한국분자세포생물학회 2022 Molecules and cells Vol.45 No.10
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has posed a serious threat to global public health. A novel vaccine made from messenger RNA (mRNA) has been developed and approved for use at an unprecedented pace. However, an increased risk of myocarditis has been reported after BNT162b2 mRNA vaccination due to unknown causes. In this study, we used single-cell RNA sequencing and single-cell T cell receptor sequencing analyses of peripheral blood mononuclear cells (PBMCs) to describe, for the first time, changes in the peripheral immune landscape of a patient who underwent myocarditis after BNT162b2 vaccination. The greatest changes were observed in the transcriptomic profile of monocytes in terms of the number of differentially expressed genes. When compared to the transcriptome of PBMCs from vaccinated individuals without complications, increased expression levels of IL7R were detected in multiple cell clusters. Overall, results from this study can help advance research into the pathogenesis of BNT162b2-induced myocarditis.
윤보경,장웅조 한국무용교육학회 2024 한국무용교육학회지 Vol.35 No.1
In this action research, we explored the practices of inclusive arts education through collaborative exchanges between artists with disabilities and non-disabled artists. Our approach, rooted in the philosophy of inclusive arts, emphasized the unique identities and diversity of individuals with disabilities. The study followed a participatory action research methodology, involving stages of research, imple- mentation, reflection, and recognition. Observations revealed that artists with dis- abilities embraced their artistic experiences, immersing themselves deeply, dis- covering their unique identities, and internalizing the experiences positively. The collaborative process also allowed non-disabled artists to confront and reassess their previous discriminatory beliefs and negative preconceptions about disability, broadening their creative horizons. Our findings highlight the potential of artistic interaction in a non-face-to-face setting, underscoring that the success of such interactions hinges not on technology, but on the embracing of the ‛inclusive arts’ educational philosophy.
요양병원 간호사의 임파워먼트, 감염관리 조직문화, 감염관리 인지도가 감염관리 수행도에 미치는 영향
윤보경,이현주 병원간호사회 2022 임상간호연구 Vol.28 No.2
Purpose: The purpose of this study was to examine the influence of empowerment, infection control organizational culture, and infection control awareness on infection control performance among nurses in long-term care hospitals. Methods: A descriptive survey study was conducted with 125 nurses as subjects who had been working for at least six months in four long-term care hospitals located in Busan metropolitan city and Gyeongsangnam-do Province. Data were collected from September 30 to October 28, 2021 and analyzed using t-test, one-way ANOVA, Pearson’s correlation coefficients, and stepwise multiple regression with SPSS/WIN 26.0. Results: The results showed that infection control performance had significant correlations with empowerment (r=.36, p<.001), infection control organizational culture (r=.51, p<.001), and infection control awareness (r=.75, p<.001). Multiple regression analysis for infection control performance revealed that the most powerful predictor was infection control awareness (β=.70, p<.001). Empowerment, infection control awareness and awareness of infection control guidelines explained approximately 60.0% of the variance in infection control performance. Conclusion: Findings indicated that various factors are related to the infection control performance among nurses in long-term care hospital. Based on the results of this study, further development and application of the programs to enhance empowerment and infection control awareness are needed in order to improve the infection control performance of nurses in long-term care hospitals. 목적: 본 연구는 요양병원 간호사의 임파워먼트, 감염관리 조직문화, 감염관리 인지도가 감염관리 수행도에 미치는 영향을 규명하기 위해 시행되었다. 방법: 부산광역시와 경상남도 소재 4개 요양병원에 6개월 이상 근무 중인 간호사 125명을 대상으로 수행한 서술적 조사연구로, 자료수집은 2021년 9월 30일부터 10월 28일까지 수행되었으며, IBM SPSS/WIN 26.0 프로그램으로 t-test, One-way ANOVA, Pearson’s correlation coefficients, Stepwise multiple regression을 실시하였다. 결과: 감염관리 수행도는 임파워먼트(r=.36, p<.001), 감염관리 조직문화(r=.51, p<.001), 감염관리 인지도(r=.75, p<.001)에서 유의한 양의 상관관계가 있었다. 다중회귀분석 결과 감염관리 인지도(β=.70, p<.001)가 가장 영향력이 큰 것으로 나타났다. 감염관리 수행도에 대한 임파워먼트, 감염관리 인지도, 감염관리지침 인지 여부 변수의 설명력은 60.0%였다. 결론: 연구결과는 다양한 요인이 요양병원 간호사의 감염관리 수행도에 영향을 미치는 것으로 확인되었다. 본 연구결과를 토대로 추후 요양병원 간호사의 감염관리 수행도를 향상시키기 위해 임파워먼트와 감염관리 인지도를 높이기 위한 프로그램 개발과 적용이 필요하다.