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연중독치료시 혈중연, 뇨중연, 뇨중 Coproporphrin, 뇨중 ${\delta}$-Aminolevulinic acid의 변화
유병국,Yoo, Byoung-Kook 대한예방의학회 1978 Journal of Preventive Medicine and Public Health Vol.11 No.1
In order to study the change of laboratory parameters of lead poisoning, 8 persona who had not been treated previously for lead poisoning (Group 1 and 6 persons who had been inadequately treated for few months for chronic lead poisoning at local clinic (Group 2) were examined. They had occupational exposure to lead for 3 to 18 years (mean, 7.6). In group 1 blood lead, urine lead, urine coproporphyrin and ${\delta}$-aminolevulinic acid levels before our treatment exceeded the critical levels of lead poisoning. In group 2 urine lead level exceeded but blood lead, urine coproporphyrin and ${\delta}$-aminolevulinic acid levels were within normal limits. All of them were treated with D-penicillamine for 4 months as inpatients at Industrial Accident Hospital. The dose of D-penicillamine was the same in all patients; 600 mg per day p.o. and the chelating agent was administer every other week. For laboratory analysis, 24 hour urine and 10 gm of whole blood were collected every 1 month on last day of non-administration period. The results were as follows: 1. It was found that urine lead level was decreased below the cirtical level of lead poisoning after 4 month's treatment with D-penicillamine and blood lead level was decreased more progressively below the critical level after 1 month treatment. 2. Urine coproporphyrin and ${\delta}$-aminolevulinic acid levels were decreased progressively to normal range after 1 month treatment. 3. Two months after treatment, blood lead, urine lead, urine coproporphyrin and ${\delta}$-aminolevulinic acid levels showed some increasing trends. 4. Urine lead level should be checked in a person who had been inadequately treated with chelating agents because blood lead, coproporphyrin and ${\delta}$-aminolevulinic acid might be in normal range.
유병국,이재희,신선주,황을원,권혁빈 한국식물학회 2013 Journal of Plant Biology Vol.56 No.2
EREBP (ethylene responsive element binding protein) and WRKY (wizz-like transcription factor) are known to play roles in plant tolerance to abiotic stresses, such as low temperatures. Previously, we used cDNA microarrays and Northern blot analysis to determine the mechanisms responsible for those underlying defenses. These analyses led to the identification of CaEREBP-C1, -C2, -C3 and CaWRKY1A genes that encode the ethylene responsive element binding protein and wizz-like transcription factors, respectively, from hot pepper (Capsicum annuum). In that study, we demonstrated that the CaEREBP-C1, -C2, -C3 and CaWRKY1A genes were strongly induced by cold stress. Here, we used Tiplasmid and Agrobecterium-mediated transformation to engineer CaEREBP-C1, -C2, -C3 and CaWRKY1A under control of the CaMV 35S promoter for constitutive expression in transgenic plants. The resultant transgenic plants exhibited significantly increased tolerance to low temperatures. In addition, none of the CaEREBP-C1, -C2, -C3 and CaWRKY1A transgenic plants showed visible phenotypic alteration when compared to wild type plants. Taken together, these results suggest that CaEREBP-C1, -C2, -C3 and CaWRKY1A play important biological roles in conferring plant cold stress tolerance.
미지의 마찰력을 갖는 로봇 매니퓰레이터에 대한 적응보상기
유병국,한종길,양근호,Yoo, Byung-Kook,Han, Jong-Kil,Yang, Keun-Ho 한국융합신호처리학회 2005 융합신호처리학회 논문지 (JISPS) Vol.6 No.3
본 논문은 미지의 마찰력을 갖는 로봇 매니퓰레이터에 대하여 퍼지시스템을 이용한 적응보상기를 제안한다. 일반적인 로봇제어이론에서는 대부분 마찰력을 무시하거나 단순히 다이나믹 마찰력만을 고려한다. 본 논문에서는 다이나믹 마찰력뿐만 아니라 비스코스 마찰력까지도 고려한 제어방식이다. 마찰력이 관절마다 결부되지 않는다는 성질을 이용하여 각 관절에 해당하는 마찰력을 SISO 퍼지시스템으로 근사하며 전체제어시스템이 안정도를 Lyapunov 안정도 이론을 이용하여 증명하고 적절한 적응법칙을 설계한다. 제안된 제어방식의 타당성을 보이기 위해 2-링크 로봇 매니퓰레이터에 대하여 컴퓨터 시뮬레이션을 보이고 각 링크에 대한 마찰력을 퍼지시스템이 잘 근사한다는 것을 보인다. This paper presents an adaptive compensator using the fuzzy systems for robot manipulator with unknown frictions. In general, frictions are neglected or dynamic frictions are only considered in robot control theories. The proposed control method considers viscous frictions as well as dynamic frictions. Using the property that the frictions of joints are decoupled, SISO-fuzzy systems are utilized to approximate each friction. The stability of overall control system is proven and the adaptive laws are derived based on Lyapunov stability theorey. To verify the validity of the proposed control strategy, the results of computer simulations are shown for 2-link robot manipulator. The ability of approximating of the fuzzy system is also shown.
An Integration Type Adaptive Compensator for a Class of Linearly Parameterized Systems
유병국,양근호,Yoo Byung-Kook,Yang Keun-Ho The Korea Institute of Convergence Signal Processi 2005 융합신호처리학회 논문지 (JISPS) Vol.6 No.2
본 논문은 선형적으로 파라미터화된 시스템에 대한 보상방식을 제안한다. 이 보상기는 전형적인 선형 제어기와 적분형의 적응법칙을 갖는 적응 관측기로 구성되며 이 때 적응법칙은 SG 알고리즘에 근거하여 설계된다. 제안된 보상전략에서는 다른 여러 연구에서 제안된 중간함수 대신에 growth조건, convex조건, attainability조건, 그리고 pseudo gradient 조건을 만족하는 함수들로 적응법칙이 설계된다. 제안된 방식은 추적오차에 대한 점근적 안정도 및 파라미터에 대한 추정오차의 bounded stability를 만족한다. 예제를 통하여 제안된 보상방식의 타당성을 보인다. 그리고 기존의 방식인 Huang의 방법과의 비교를 통해 제안된 방식이 정상상태에서의 파라미터 오차가 더 작아짐을 보인다. A compensation scheme for a class of linearly parameterized systems is presented. The compensator consists of a typical linearizing control and an adaptive observer with integration type update law, which is based on Speed Gradient (SG) algorithm.. Instead of the intermediate functions of the compensation schemes suggested by other researchers, the proposed compensator is designed with some design functions which guarantee the growth, convexity, attainability, and pseudo gradient conditions in the update law. The scheme achieves the asymptotic stability of the tracking error and the boundedness of the estimation errors. A numerical example is given to demonstrate the validity of the proposed design.