나의 주장-98년 설치되는 특허법원에 기술판사제 도입해야

양지원,Yang, Ji-Won 한국과학기술단체총연합회 1994 과학과 기술 Vol.27 No.11

한국의 과학기술 어디까지 왔나 - 발효 기술, 아미노산 발효기술 선진국 수준

양지원,Yang, Ji-Won 한국과학기술단체총연합회 2000 과학과 기술 Vol.33 No.10

우리나라의 생명공학기술 수준은 선진국을 100으로 볼 때 65정도로 열세이지만 분야별로 강세를 보여온 발효기술은 90정도로 선진국에 근접해 있으며 특히 아미노산 발효기술은 높게 평가를 받고 있다. 21세기 선도산업으로 꼽고 있는 생물산업의 경쟁력 우위를 점하기 위해선 더 많은 기술적ㆍ경제적인 투자가 절실하다.

누에(Bombyx mori) 번데기 및 한약재의 In Vitro 에스트로젠 활성

양지원,최은미,권무길,구성자,Yang Ji-Won,Choi Eun-Mi,Kwon Mu-Gil,Koo Sung-Ja 동아시아식생활학회 2005 동아시아식생활학회지 Vol.15 No.3

In this study we report on the estrogen activity of silkworm pupa and herb extracts in vitro. The estrogenic activity of these resources was investigated by competition binding assays with estrogen receptor $\alpha(ER{\alpha})\;or\;ER{\beta}$, and viability of MCF-7 cells, a human breast cancer cell line. Saturation ligand-binding analysis of $ER{\alpha}\;and\;ER{\beta}$ revealed that all plant extracts competed with estrogen ligand for binding to both ER subtypes with a similar preference and degree and competed stronger with ligand for binding to $ER{\beta}\;than\;to\;ER{\alpha}$. The highest $ER{\alpha}-binding$ sample was silkworm pupa aqueous extract The highest $ER{\beta}-binding$ sample was silkworm pupa oil. These samples were further tested for bioactivity based on their ability to regulate cell growth rate in ER(+) breast cancer cell line, MCF-7 cells. Our studies showed that silkworm pupa, soritae, sesame, yam, pueraria, malt, ginseng, Polygonum multiflorum, and Curcuma longa significantly stimulated the growth of MCF-7 cells (P<0.05). In summary, these results suggested that silkworm pupa and herbs might be useful as potential phytoestrogens.

Myelin Water Fraction MRI in a Case of Clinically Probable Amyotrophic Lateral Sclerosis

양지원,이종호,김응엽,신동훈,Yang, Jiwon,Lee, Jongho,Kim, EungYeop,Shin, Dong Hoon The Korean Society of Clinical Neurophysiology 2016 Annals of Clinical Neurophysiology Vol.18 No.1

Amyotrophic lateral sclerosis (ALS) is a progressive motor neuron degenerative disease that clinically manifests both upper and lower motor neuron signs. However, it is unknown where and how the motor neuron degeneration begins, and conflicting hypotheses have been suggested. Recent advanced radiological techniques enable us to look into ALS neuropathology in vivo. Herein, we report a case with upper motor neuron-predominant ALS in whom the results of brain magnetic resonance imaging (MRI) and myelin water fraction MRI suggest axonal degeneration.

국내 시판 누룽지의 물리화학적 특성 및 항산화 성질 연구

양지원,최일숙,Yang, Ji-won,Choi, Il Sook 한국식품조리과학회 2016 한국식품조리과학회지 Vol.32 No.5

Purpose: Nurungji is a traditional Korean food made by yellowish scorched rice. After getting gelatinization of rice, a thin crust of scorched rice will usually be left in the bottom of the traditional cooking pot. In this study, physicochemical characteristics and antioxidant properties of five commercial nurungji products (CNP1, CNP2, CNP3, CNP4, and CNP5) were evaluated. Methods: Physicochemical properties of the five commercial nurungji products were evaluated with AOAC method. The antioxidant activities were assessed using the 1,1-diphenyl-2-picryl hydrazyl (DPPH), 2,2-azinobis-(3-ethyl-benozothia zoline-6-sulfonic acid)(ABTS), ferric reducing antioxidant power (FRAP), and reducing power assays. Results: Water content was the highest in CNP3, followed by CNP1, CNP2, CNP5, and CNP4. Crude ash content of all nurungji was less than 1%. In Hunter color parameter, the significantly highest a value (redness) and b value (yellowness) were measured in the CNP4 product, meanwhile the lowest in CNP3 (p<0.05). The nurungji products of CNP4 and CNP5 had the significantly higher content in total polyphenols and total flavonoids, compared to those of other products. CNP3 and CNP2 had the lowest in total polyphenols and total flavonoids, respectively. CNP4 and CNP5 products showed the significantly higher values in antioxidant activities, whereas CNP3 had the lowest activity. Conclusion: The high value of antioxidant activities in CNP4 and CNP5 might have been affected primarily by the total polyphenols with increasing browning color during the heat treatment.

Evaluation on the Quality of Fresh, Conventionally Heated and Ohmically Heated Mulberry Fruit Juice

양지원,한대석,이창호,박성진,김영언,Yang, Ji-Won,Han, Dae-Seok,Lee, Chang-Ho,Park, Sung-Jin,Kim, Young-Eon The East Asian Society of Dietary Life 2014 동아시아식생활학회지 Vol.24 No.1

The aim of this study was to establish the superiority of ohmic heating over conventional heating for the sterilization of mulberry juice. Heat treatment of fresh juice significantly reduced the concentration of soluble solids, lowered the pH, and lowered the reducing sugar content (p<0.01). Color measurements showed decreases in the L and a values and increases in the b, H and C values after heat treatment, although the total color differences were smaller after ohmic heating than after conventional heating of fresh juice. The antioxidant capacities, such as reducing power, FRAP, and DPPH, decreased in the order of fresh juice, ohmically heated juice and conventionally heated juice. Furthermore, the anthocyanin, flovonoid, and total antioxidant capacities of the juices significantly decreased in the same order. Sensory evaluations showed no difference between fresh and ohmically heated mulberry fruit juice excluding off-flavor, whereas conventionally heated juice received significantly lower evaluations. The microbial counts were zero in the juice after either heat treatment. Thus, ohmic heat treatment can be effectively used to sterilize fresh mulberry juice to obtain good shelf life with minimal physicochemical, color, antioxidant and sensory deterioration.

국내 재활용 건축 재료 활용방안 연구

양지원(Yang, Ji-Won),유해연(Yoo, Hae-Yeon) 대한건축학회 2018 대한건축학회 학술발표대회 논문집 Vol.38 No.2

As interest in sustainable architecture has increased, research on the recycling method of waste materials has been actively conducted. The purpose of this study is to examine the domestic and foreign cases using recycled building materials and to analyze the characteristics and suggest the improvement value and future improvement direction. For this, the preceding research was conducted. second, I examined domestic regulations. third, Analyzes the characteristics of domestic and foreign cases, and revealed the values and limitations. Finally, we sugest a direction for domestic activation in the future.

학교부적응 청소년의 자아탄력성 향상을 위한 해결중심적 집단미술치료

양지원(Yang, Jee Won) 한국공공관리학회 2017 한국공공관리학회 학술대회 Vol.2017 No.11

본 연구는 해결중심 집단미술치료가 학교부적응 청소년들의 자아탄력성 향상에 미치는 효과에 관하여 살펴보기 위해 경기도 K시의 K중학교 학교부적응 청소년 30명을 대상으로 송혜리(2009)의 자아탄력성척도를 사전검사 후 해결중심적 집단미술치료의 참여를 희망하는 20명의 대상자를 선정하여 10명씩 실험집단과 통제집단으로 무작위 배치하였다. 실험집단에는 2014년 9월15일 ∼ 2014년 12월22일까지 사전 · 사후검사를 포함한 총 12회기의 해결중심적 집단미술치료를 실시하였으나 통제집단은 사전·사후 검사만 실시하였다. 실험·통제집단간의 동질성 확인을 위해 맨 휘트니 U 검정(Mann Whitney U test)을 실시하였으며, 이후 사전 · 사후 차이를 확인하기 위해 윌콕슨 부호 순위 검정(Wilcoxon’s signed ranks test)을 실시하였다. 또한 자기평가 질문지와 척도지를 활용하여 청소년 스스로가 느끼는 변화정도를 확인하였다. 연구결과 해결중심적 집단미술치료는 학교부적응 청소년의 자아탄력성 향상에 효과적인 방법으로 활용될 수 있는 것으로 나타났다. This study is about the effects of the solution-focused group art therapy on improving ego-resilience of school maladjusted adolescents. The pre-test, based on ego-resilience checklist made by 송혜리 in 2009 was conducted for 30 students who had difficulties to adapt school life in K middle school at K city, Gyeonggi province. 20 out of the 30 students were chosen to the participants for this study and randomly divided into an experimental group and control group, with 10 in each group. The experimental group received a 12 session solution-focused group art therapy including pre- and post-tests while the control group was only given pre- and post-tests. Mann Whitney U test was conducted for checking the equivalence between experimental- and control group, and then Wilcoxon"s signed ranks test was conducted for checking the differences between pre- and post test. The test was conducted to find out how many changes the participants think they have through adolescent"s self-assessment with survey and checklist. This study found that the solution-focused group art therapy program improved the school life adaptation competency of the participants. In conclusion, the findings suggest that the solution-focused group art therapy can be a good approach to help adolescents to improve their school life adaptation ability.

거래사례를 이용한 토지 과세평가의 수직적 형평성 분석

양지원(Yang, Ji-Won),유선종(Yoo, Seon-Jong) 한국주거환경학회 2015 주거환경(한국주거환경학회논문집) Vol.13 No.4

Publicly Announced Price of land system, a mass appraisal scheme, was introduced in Korea in 1989. The system has been continually improved to enhance the public confidence of the publicly announced land price since its introduction. But the reality is that the problem of the propriety of the publicly announced land price has been raised with the introduction of the report system of the real transaction price for real property. This study attempted to elicit policy implications needed to provide the clue for fair taxation by making an empirical analysis of vertical equity of the publicly announced land price. For the purpose of analysis, this study adopted the sales price applied to the sales comparison approach at the time of assessing the publicly announced price of reference land in 2014 and data on the publicly announced individual land price with January 1, 2014 as the basis year. Vertical equity was tested through ratio analysis using the PRD indicator and traditional regression analysis(Bell model, Clapp model). As a result, the test of vertical equity showed that there existed inequity in most areas, in use zones, in land use situations, and in the taxable value level. Analysis of the cause for assessment inequity showed that there was a difference in it according to the object of analysis(bare ground, building lot, bare ground + building lot). It was found that the possibility of error in the application of the abstraction method might have an effect on the problem of inequity. This study attempted to make an empirical analysis of the equity of the publicly announced land price and elicit policy implications based on its findings. This is expected to provide a clue to enhance assessment equity and contribute to the fair distribution of taxation burden.

창의융합형 인재양성을 위한 프로젝트 학습 설계

양지원(Ji-Won Yang),이형옥(Hyeong-Ok Lee) 한국컴퓨터교육학회 2023 한국컴퓨터교육학회 학술발표대회논문집 Vol.27 No.1