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미생물에 의한 치자 Iridoid 배당체 변환 청색소의 생산
양승각,전기붕 대한화장품학회 1987 대한화장품학회지 Vol.13 No.1
Seven bacterial strains capable of conversing Gardenia irridoidglucoside into blue color was isolated on nutrient agar plates with 0.1 % water extracted solution of Gardenia's dryed seed. In the seven, strain No. C<sub>2</sub> was most effective in the production of blue color. The optimal conditions in production of blue color were when initial pH of medium was 7.0 and cultivation temperature was 35℃. In 5ℓ-Jar fermantor, the powder of blue color was produced about 15% (W /W). And the color was relatively stable in our test.
양승각 한국미생물학회 1988 微生物과 産業 Vol.14 No.2
일반적으로 미생물들은 균종에 따라 독특한 색소를 생성하거나 수율이 낮다는 문제점을 갖고 있었다. 그러나 최근 발효기술의 발달및 유전자 재조합, 세포 융합등의 발달로 미생물 색소의 개발 가능성이 한층 높아졌다. 따라서 미생물에 의해 생산 가능한 천연색소에 대하여 그 현황과 전망을 개략적으로 기술하고자 한다.
상백피의 Sanggenon C에 의한 Streptococcus mutans의 생육 및 균부착 저해효과
박원재(Won Jae Park),이형재(Hyung Jae Lee),양승각(Seung Gak Yang) 대한약학회 1990 약학회지 Vol.34 No.6
The methanolic extract of the root-bark of Morus alba L.(Mulberry tree) has the potent antibacterial activity against Streptococcus mutans. Its active component was identified to be sanggenon C. The active had stronger anti-bacterial activity than berberine, having minimum inhibitory concentration(MIC) of 25mcg/ml. Moreover, the inhibitory effect of this component on the cellular adherence of streptococcus mutans to glass surfaces also was more remarkable than that of berberine in the presence of glucosyltransferase(GTase) and sucrose in vitro. These results indicated that sanggenon C may play an important role in inhibiting plaque formation and caries incidence.