동아시아에서 黃漆樹의 활용에 대한 硏究

안영수(Ahn Young-su),류정아(Lyu Jeong-ah) 한국의사학회 2020 한국의사학회지 Vol.33 No.1

한국의 특산 수종인 黃漆樹(Dendropanax morbifera H.Lév)는 고대로부터 동아시아에서 그 汁을 채취하여 가공한 黃漆을 희소성과 의례성을 지니는 기물인 황제의 갑옷과 시초점의 점괘를 기록하는 版에 칠하는 용도로 사용하였을 뿐 아니라 신라에서는 地鎭具의 예물로도 사용하였다. 이는 黃漆이 지니는 防水, 防濕, 防錆, 防腐, 防蟲, 抗破斷性 및 뛰어난 保存 효능에 기인한 것으로, 조선 중기 간행된 [牛馬羊猪染疫病治療方]에는 제주도에서 나는 黃漆을 수입산 약재인 安息香을 대신하는 鄕産의 약재로써 태워서 그 연기가 코에 스미도록 하는 방법으로 소의 전염병에 사용한 기록이 보인다. 이후로 [耽羅志], [輿地圖書] 등에 安息香과 黃漆을 동일시하는 기록 및 [星湖僿說]에 내복할 수 있는 약재로 인식한 기록이 보인다. 2000년 안덕균은 [韓國本草圖鑑]에 黃漆樹의 뿌리와 가지를 “楓荷梨”라는 藥名으로 本草에 편입하고 性味와 效能·主治 및 내복하는 방법을 제시하였다. 현재까지 黃漆樹의 精油성분을 비롯하여 뿌리, 가지, 잎, 꽃, 열매, 樹脂 등 다양한 부분에 대해 보건의료에 유의미한 다양한 효능이 있음을 탐색하고 확인하는 연구들이 다수 보고되고 있다. 黃漆樹의 쓰임에 대한 역사적 연혁 및 최신 연구 성과들로부터 黃漆樹가 지니는 다양한 효능을 한의학적으로 辟邪, 開竅, 醒心, 安神, 疎泄, 去故生新 등 용어로 귀납할 수 있다 생각되며, 이러한 인식이 黃漆樹의 활용 확장에 일정한 역할을 할 수 있을 것으로 본다. Essence of the Hwangchil tree (黃漆樹 Dendropanax morbiferus H.Lév.) has been used for various purposes, like waxing emperor’s armors, covering an astrology board, or, during the Silla Dynasty, burying it to block something bad in the soil symbolically. Essence of the Hwangchil tree was known to have remarkable preservation effects such as waterproofing, damp-proofing, rust-proofing, and moth-proofing as well as not being easily peeled off from even soft surfaces like paper. There is a record in Prescriptions for Epidemic diseases of Cows, Horses, Sheep, and Pigs (牛馬羊猪染疫病治療方), published in 1541, of Hwangchil that is local to Jeju Island being used instead of benzoin (安息香), of burning Hwangchil, and of making cows inhale its smoke to prevent plague among them. Along the same lines, there are records in the Local Chronicle of Tamra (耽羅志) and the Book of Earth Geography (輿地圖書) that identify Hwangchil with benzoin. In Seonghosaseol (星湖僿說), a book written by Lee Yik in around 1760, it is acknowledged that Hwangchil could be medicinal herb. In 2000, Ahn Duk-Kyun registered the roots and branches of Hwangchil tree as ‘Boncho’ (本草 herbal medicine) in the Pictorial Book of Korean Medicinals (韓國本草圖鑑) and presented the method of taking it for medical purpose. Researchers have suggested that Hwangchil essence as well as diverse parts of the plant such as its roots, branches, leaves, flowers, fruits, and gum have various meaningful medicinal properties. Regarding the history and recent researches of using Hwangchil tree, it has various medicinal probabilities such as, ‘dispersing miasma’ (辟邪), ‘opening holes’ (開竅), ‘waking the heart’ (醒心), ‘smoothing spirits’ (安神), ‘piercing the block’ (疎泄), ‘removing the old and welcoming the new’ (去故生新). This paper contributes ideas about how to expand the uses of Hwangchil Tree.

PS 강봉으로 일체화된 강합성 라멘교의 거더-교대 접합부에 대한 피로 성능 평가

안영수(Young-Soo Ahn),오민호(Min-Ho Oh),정지승(Jee-Seung Chung),이상윤(Sang-Yoon Lee) 한국콘크리트학회 2012 콘크리트학회논문집 Vol.24 No.3

셸리(Percy Byshe Shelley)의 『인생승리』 (The Triumph of Life) 연구

안영수 ( Young Soo Ahn ) 경희대학교 인문학연구원 2002 인문학연구 Vol.6 No.-

DMADOV와 TRIZ의 통합을 이용한 새로운 혁신 전략

안영수(Ahn, Yong-Soo),황인극(Hwang In Keuk) 한국산학기술학회 2008 한국산학기술학회 학술대회 Vol.- No.-

TRIZ는 문제분석을 통한 모순을 찾아내어 이를 해결하는 Process에 역점을 두는 방법론으로 알트슐러와 그의 동료에 의해 수십만건의 특허를 분석하는 과정에서 시대와 분야를 막론하고 동일한 유형의 문제가 반복되고, 이를 해결하는 방법도 동일함을 규명하여 이를 체계 화한 방법론으로, 현재 핵심기술 개발 및 창의적 문제 해결 방법론으로 각광받고 있다. 그러 나 TRIZ 역시 문제점을 가지고 있으며, 그것은 초기 과제 정의가 어렵다는 것과 효과산출 을 어떻게 하면 객관화 할 수 있을 것인가 이며, 또한 도출된 아이디어를 최적화 하는 방안 이다 하나의 방법론만으로는 모든 과제 해결을 위해 일괄 적용 시키는 것은 모순이며, 경영기법 간의 연계를 통한 경영효과 극대화가 필요하다. 이 논문에서는 6시그마와 TRIZ 방법론 분석을 통한 각 방법론의 이해를 높이고, 이를 바탕으로 서로 방법론간의 연계의 필요성을 확 인 및 방법론 간 연계를 위한 연계 프로세스 모델을 제시하고자 한다.

Haloperidol 이 심혈관계에 미치는 영향

안영수(Young-Soo Ahn) 대한약리학회 1975 대한약리학잡지 Vol.11 No.2

Haloperidol, a butyrophenone, was synthetized by Janssen and introduced for the treatment of psychosis. Although structurally different from the phenothiazines, the butyrophenones share many of their pharmacological properties, such as inhibition of conditioned avoidance response, blocking effect of amphetamine reaction, producing catalepsy, antishock effect and protection against the lethal effects of catecholalmines. Chlorpromazine can lower the arterial blood pressure through its adrenergic blocking activity, its direct effect in relaxing vascular smooth muscle, its direct effect in depressing the myocardium and its action in a complex manner on the central nervous system. In the case of haloperidol, however, was not clarified the mechanism of lowering the blood pressure. The present paper describes the effects of haloperidol on cardiovascular system to investigate the mechanisms of its actions on the arterial blood pressure. The results are followings; 1. In anesthetized cats, intravenous administration of haloperidol and chlorpromazine in the dose of 0.1mg/kg produced a slight decrease in the blood pressure, which followed by complete recovery within 30 ~ 60 minutes. In the dose of 3mg/kg, however, both produced an abrupt and marked decrease of the blood pressure, which followed by delayed recovery. 2. Haloperidol in the dose ranges of 0.1mg to 3.0mg/kg tended to produce the heart rate slowing in the cats, while chlorpromazine has no effect on the rate. 3. Following administration of haloperidol or chlorpromazine, epinephrine reversal in the arterial blood pressure was observed in the cat, however the responses of norepinephrine and acetylcholine were little affected. 4. In the isolated rabbit atrium the contractility was depressed by haloperidol in the doses over 0.5mg per 100ml, but the rate was not affected. In contrast, the epinephrine-induced contractility was not depressed after haloperidol treatment. However, the increased rate of atrium by epinephrine was partially blocked after haloperidol. 5. In the isolated rabbit aortic strip, epinephrine-induced contraction was blocked by haloperidol. With the above results, it may be concluded that the hypotensive effect of haloperidol was largely due to α-adrenergic blocking properties and the direct effect in depressing the myocardium as well as its action on central nervous system.

흰쥐 말초 혈액 림프구의 분자량 44 kD 단백의 인산화

안영수(Young Soo Ahn),주일로(I-Lo Jou),오도연(Do Yeun Oh),임승욱(Seung Wook Lim),박경선(Kyung Sun Park) 대한약리학회 1991 대한약리학잡지 Vol.27 No.2

흰쥐 말초혈액에서 얻은 T 림프구를 아드레날린성 β-수용체 효현제 및 concanavalin A(Con-A)로 자극해 다음과 같은 결과를 얻었다. 자극이 없는 상태에서의 주 인산화 단백은 분자량 44kD, 등전점 6.8의 단백이었으며 효현제로 자극시키면 분자량 44kD, 등전점 6.3의 단백이 새로이 인산화되어 나타났다. 이 분자량 44kD, 등전점 6.3의 단백은 forskolin에 의해 역시 인산화되며 A-kinase 억제제인 H-8을 전처치하면 인산화의 억제가 나타났다. 또한 Con-A로 자극시키면 44 kD/pI 6.3 단백의 인산화가 증가되었으며 이 인산화의 증가는 CaM kinase 억제제인 W-7 전처치에 의해 억제되었다. H-7은 분자량 44 kD, 등전점 6.8 단백의 인산화를 감소 시켰다. 이상의 결과로 분자량 44 kD 등전점 6.3의 단백은 A-kinase와 CaM kinase 모두에 의해 인산화 되는 기질단백으로서 tryptic peptide map상에서 44 kD/pI 6.8 단백과 44 kD/pI 6.3 단백은 서로 다른 단백임을 알 수 있었다. Using T-lymphocytes obtained from rat peripheral blood, we found that the 44kD/pI6.8 protein was the major phosphoprotein of T-lymphocytes under basal condition, and that the 44kD/pI6.3 protein was a new phosphoprotein appeared in T-lymphocytes stimulated with β-agonist. The phosphorylation of the 44kD/pI6.3 protein was also induced by forskolin but inhibited by H-8 pretreatment. To clarify the character of the 44kD/pI6.3 protein, we used Con-A and kinase inhibitors, H-7 and W-7. Con-A stimulation induced phosphorylation of 44kD/pI 6.3 protein but that was inhibited by W-7 pretreatment. The phosphorytation of 44kD/pI6.3 protein was not induced by the PKC activator, PMA. Instead, the phosphorylation of 44kD/pI6.8 protein was reduced by H-7, a PKC inhibitor. From the above results,it can be concluded that the 44kD/pI6.3 protein can be a common substrate for A-kinase and CaM kinase. The two dimensional tryptic peptide mapping revealed that the 44kD/pI6.8 and 44kD/pI6.3 proteins are different.

Studies on the Reduction of SO₂ Injury to Hibiscus syriacus L. by Use of Growth Regulant, CCC

Ahn Young-Soo(安永秀),Yeam Do- Yi(廉道義) 한국원예학회 1977 Horticulture, Environment, and Biotechnology Vol.18 No.2

고양이에서 체표냉각에 따른 심혈관계 변동에 관한 연구

안영수(Young Soo Ahn),고창만(Chang Mann Ko),이우주(Woo Choo Lee) 대한약리학회 1983 대한약리학잡지 Vol.19 No.1

Hypothermia is an essential preparatory procedure for cardiac surgery, which lows the metabolic rate and myocardial oxygen demand. However, hypothermia itself is a stress enough to change the tonus of sympathoadrenal system, especially the cardiovascular responses to the catecholamines. It is reported that the positive chronotropic and inotropic response of catecholamines is exaggerated during hypothermia because of decreased norepinephrine uptake at the junctional cleft or decreased catecholamine metabolism. On the other hand, there are evidences of diminished catecholamines responses in low temperature ana further, interconversion of adrenergic receptors is also suggested. Present investigation was planned to observe the cardiovascular changes and its responses to catecholamines during surface hypothermia in cat. Healthy mongrel cats, weighing 2 ~ 3 kg, anesthetized with secobarbital(30 mg/kg), were permitted to hypothermia by external cooling technic. Esophageal temperature, ECG (lead II), heart rate, left ventricular pressure with dP/dt, carotid artery pressure and left ventricular contractile force were monitored with Polygragh (Model 7, Grass), and the respiration was maintained with artificial respirator (V 5 KG, Narco). Followings are summarized results. 1) Surface cooling caused progressive decrease of body temperature and reached l8.8 ± 0.8˚C and 16.9 ± 0.6˚C in 120 and 150 min respectively, after immersion into ice water, and ventricular fibrillation was developed at 20.4 ± 0.65˚C. 2) Heart rate, blood pressure and myocardial contractility were decreased after initial increase as the body temperature falls. 3) Systolic and diastolicdd P/dt of left ventricular pressure were decreased and that the decrement of diastolic dP/dt was more marked. 4) On ECG, ST depression, Twave inversion and prolongation of PR interval were prominent in hypothermia, and moreover, the prolongation of PR interval was marked just prior to the development of ventricular fibrillation. 5) The cardiovascular responses to catecholamines, especially to isoproterenol, were suppressed under hypothermia.

영국 델라 크루스칸 문학세계(The Literal World of the English Della Cruscans)와 블레이크의 성적 묘사

안영수 ( Young Soo Ahn ) 경희대학교 인문학연구원 2004 인문학연구 Vol.8 No.-

T. S. 엘리엇과 낭만주의

안영수(Ahn Young-soo) 한국T.S.엘리엇학회 1995 T.S. 엘리엇 연구 Vol.2 No.-