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안세아,이한빈,김윤,김진권,김현숙,김원찬,김옥준,오승헌 연세대학교의과대학 2013 Yonsei medical journal Vol.54 No.4
Purpose: The pulsatility index (PI), measured by transcranial Doppler (TCD), is a surrogate marker for distal vascular resistance in cerebral arteries, and elevated plasma total homocysteine (tHcyt) is regarded as a cause of ischemic stroke, including lacunar infarction. We investigated the relationship between the PI of cerebral arteries and plasma tHcyt in patients with lacunar infarction. Materials and Methods: Plasma tHcyt level and TCD examination were performed in 94 patients with lacunar infarction. Mean flow velocity (MFV) and PI were assessed at the ipsilateral middle cerebral artery (MCA) and contralateral MCA, relative to the infarction, and the basilar artery (BA). Multivariate regression analysis was conducted between log-transformed tHcyt levels (logHcyt) and the PI of individual arteries. Results: There was a significant correlation between logHcyt and the PI in all tested arteries (ipsilateral MCA: r=0.21, p=0.03; contralateral MCA: r=0.21, p=0.04; BA: r=0.35, p=0.01). In multivariate regression analysis, this significance remained unchanged after adjusting for vascular risk factors, creatinine, hematocrit and platelet count (ipsilateral MCA: β=0.26, p=0.01; contralateral MCA: β=0.21, p=0.04; BA: β=0.39, p=0.001). There was no significant association between logHcyt and MFV of individual arteries. Conclusion: A significant association between plasma tHcyt and the PI of cerebral arteries indicates that homocysteine plays a role in the increase of distal arterial resistance in lacunar infarction.
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지역사회복지서비스 청년사업단 사업의 효과 -인천지역을 중심으로-
안세아 ( Se Ah Ahn ) 한국사회보장학회 2010 사회보장연구 Vol.26 No.4
Ministry of Health and Welfare suggest social service that causes relative losses in people`s mind and it drastically weakens the meaning of family as a solution for poverty. This family crisis brings negative effect on mental, physical growth to achieve growth into whole people. Public service sector including welfare in management of results and evaluation of satisfaction with service expressed high satisfaction in Incheon servant people. After analyzing the results of the study, the following suggestions were made. First, Those people who get the social service has growth of score in many ways. Second, According to a perception of service satisfaction, those who local people answered that this service has to long term with specific system. It is necessary to make the system on social service related education service, guideline in details, and assessment during service in many local. For this, it is imperative to expand concerns and understandings of managers about social services. This is not to get accomplished people working for organization but get accomplished concerns of servant`s division and administrative supports.
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젠더적 관점에서 본 한국의 복지체제유형 논의 -남부유럽과의 비교를 중심으로-
안세아 ( Se Ah Ahn ) 한국사회보장학회 2011 사회보장연구 Vol.27 No.2
The purpose of this study is to analyse welfare regime from a gender point of view between Korea and welfare reform in Southern Europe and to compare the care work support policy with those countries. The reason being focused the policy character is that is, even though two countries have implemented different policies under the heading of work-family balance, may produce similar policy outcome in terms of birth rate and achievement level of gender-equality in family. The results of analysis of this study are as such: Firstly, those countries`s family policy character has residual welfare provision including conservatism. Second, child care policy was concentrated on support for low income family`s needs for child care rather than women`s labourer`s needs. But private child care facilities for profit are dominant in Korea. So access to those facilities is very difficult for the class including the middle class which is not supported by government, because of too expensive child care fee. As a result, father`s participation ratio at parent leave scheme became decreased. Therefore, perfect gender equality at parent leave scheme is not achieved. To sum up, care work support policy is not completely based on gender-equality participation, but it is sure parents are truly responsible for care work. Thirdly, in case of Korea, effective gender-balance policy such as male`s familization in the area of care work support isn``t introduced. It is difficult for Korean male to join the child care work due to their long working hours. In particular, regarding participation in maternity leave scheme of Korea, women are responsible for care-work. But right of women and men to care-work is not guaranteed and thereby the possibility of work-family balance is not likely. In conclusion, when care work support policy and gender regime are simultaneously implemented on the basis of holistic approach of care and possibility of gender-equality work-family balance are much likely in Korea and Southern Europe. Those countries are affiliated to residual welfare provision including conservatism.
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안세아(Ahn Se-Ah) 인문사회과학기술융합학회 2020 예술인문사회융합멀티미디어논문지 Vol.10 No.3
This study analyzed how the family structure changes as a result of OECD s global neoliberalization in early 1980s and 2014. Since change of family structure caused by global economic crises threaten finance and sustainability of welfare states, they have been restructured to respond to these external shocks. In this context, this paper focused on social expenditure structure of welfare states which is defined by three sectors through theoretical discussions. Namely, change of family policy in [de-familialization], [familialization], and [de-gendering]. Second, provision method of family policy. Third, path dependence theory of family policy. Through clustering analysis with OECD SOCX Data in early 1980s and 2014, welfare states are categorized into five types according to change of family policy and then compared the family policy path dependence. The differences of responses of welfare states was tried to explain based on path dependence theory which can be understood as institutional conditions. The conclusion on the basis of this study is that Korean welfare state have to aim to expenditure structure of Nordic welfare state such as universal idea of policy. The reason is that the institutional theories have focused on modes of institutional change, politics of institutional change, and ideas for institutional change.
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α2A-, α2B-, α2C-아드레날린 수용체 유전자 다형성과 대뇌 백색질변성과의 연관성
김미화,안세아,이한빈,추승욱,김남근,김원찬,김옥준,오승헌 대한뇌졸중학회 2011 Journal of stroke Vol.13 No.2
Background: An α2-adrenergic receptor (α2-AR, ADRA2) mediates induction of hypotension and inhibition of lipolysis and insulin secretion. We evaluated whether single nucleotide polymorphisms (SNPs) of α2A (ADRA2A), α2B (ADRA2B), and α2C (ADRA2C)adrenergic receptors are associated with cerebral white matter lesion (cWML). Methods: Total 336 study subjects who had no stroke were enrolled in this study. The Indices of cWML include total WML (TWML), periventricular WML(PVWML), and subcortical WML (SCWML) on brain fl uid-attenuated inversion recovery (FLAIR) image. Common genetic variants of ADRA2A (1780G>A), ADRA2B (Ins/Del301-303), and ADRA2C (Ins/Del322-325) were examined. Results: Among 336 study subjects, cWML was found in 66 patients (20%). In multivariate analysis, there were no signifi cant effects of all tested ADRA2 polymorphisms on TWML. Signifi cant association of ADRA2A 1780 AA genotype was found in PVWML(OR: 3.368, 95% CIs: 1.280-8.865, adjusted p-value after false discovery rate (FDR) correction=0.014) but not SCWML. Conclusion: Although SNPs of three ADRA2 subtypes failed to reach a signifi cance in overall risk for cWML, the ADRA2A 1780G>A polymorphism may be associated with development of PVWML. (Korean J Stroke 2011;13:66-73)
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