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심효섭,임범진,김명진,이우정,박찬일,박영년 대한간학회 2004 Clinical and Molecular Hepatology(대한간학회지) Vol.10 No.3
Mucinous cholangiocarcinoma, characterized by large quantities of mucin production, is a rare subtype of peripheral cholangiocarcinoma and usually shows rapid progression and a fatal outcome. We report here a case of mucinous cholangiocarcinoma in a 69 year-old man, who was infected with Clonorchis sinensis. Histologically, the tumor was an adenocarcinoma with extensive intracellular and extracellular mucin production, up to 70% of the tumor mass and there was frequent lymphovascular invasion of the tumor cells. The liver adjacent to the mass contained eggs of Clonorchis sinensis in the bile duct lumen and showed ductal epithelial hyperplasia, mucinous metaplasia and adenomatous proliferation of intramural glands. The patient was treated with a right hepatectomy. Four months after the surgery, the tumor recurred in the soft tissue of the right flank.
Improved RRS Logical Architecture using Genetic Algorithm
심효섭,정재천,Shim, Hyo Sub,Jung, Jae Chun The Korean Society of Systems Engineering 2016 시스템엔지니어링학술지 Vol.12 No.2
An improved RRS (Reactor Regulating System) logic is implemented in this work using systems engineering approach along with GA (Genetic Algorithm) deemed as providing an optimal solution to a given system. The current system works desirably and has been contributed to the safe and stable NPP operation. However, during the ascent and decent section of the reactor power, the RRS output reveals a relatively high steady state error and the output also carries a considerable level of overshoot. In an attempt to consolidate conservatism and minimize the error, this research proposes applying genetic algorithm to RRS and suggests reconfiguring the system. Prior to the use of GA, reverse-engineering is implemented to build a Simulink-based RRS model and re-engineering is followed to apply the GA and to produce a newly-configured RRS generating an output that has a reduced steady state error and diminished overshoot level.