인공 판막 환자에서 발생한 Listeria monocytogenes 심내막염 1예

신상엽,손준성,김형훈,민태훈,윤종욱,장현하,정숙인,오원섭,김성민,백경란,송재훈 대한감염학회 2002 감염 Vol.34 No.5

포스타 전시 발표 : 감염, 알레르기, 류마티스 ; 뇌수막염 및 경추부 경막의 농양으로 발현한 장티푸스 균혈증 1례

신상엽,손준성,허상택,김연숙,정숙인,오원섭,김성민,백경란,송재훈 대한내과학회 2001 대한내과학회 추계학술발표논문집 Vol.61 No.-

The impact of the size and the layout of living space on subjective well-being-cases from the UK and South Korea

신상엽 한국EU학회 2023 EU학연구 Vol.28 No.3

The size of our living space shapes so much of our lives. The physical home is the primary place where family members and roommates interact, and the size and layout of the space is fundamental to the development of relationships. Therefore, given the amount of time we spend at home, the size of our living space is expected to have a positive impact on our subjective well-being. In this study, we present the results of an empirical analysis of the effect of the size of residential space on individual subjective well-being, focusing on the case of the United Kingdom, which is facing a space shortage problem representative of Europe, and Korea, which is experiencing housing problems due to the concentration of metropolitan areas. The results show that the number of rooms per person in the UK and the size of living space per person in Korea have a positive effect on subjective well-being. Furthermore, the effects of living space size and layout on subjective well-being are heterogeneous across age, gender, marital status, and the presence of children, suggesting that the importance of space may vary depending on the individual's situation.

2003년 제주도 세균성이질 환자의 역학적 특성

신상엽,고운영,배종면 대한감염학회 2005 Infection and Chemotherapy Vol.37 No.4

Background : Shigellosis is one of the most important contagious diseases in Korea. Especially, Jeju island has been known as the main and large outbreak area in Korea. The purpose of this study was to investigate the epidemiologic characteristics of shigellosis in Jeju island, 2003. Methods : Patients with shigellosis, confirmed by culture in Jeju island in 2003, were included in this study. We retrospectively reviewed epidemiologic questionnaires, medical records, and official documents. We also collected data from direct interview with the patients with shigellosis. Epidemiological analysis was performed by 3 categorized events and ages. Results : Ninety-nine patients were included in this study. S. sonnei was identified in all of the patients. Shigellosis mainly occurred in preschool-aged children. However, there was no statistical difference according to sex. Although there were asymptomatic cases (15.15%), the chief complaints were loose stool (69.7%) and abdominal pain (12.12%). Initial symptoms in symptomatic patients were abdominal pain (43.43%) and fever (31.31%). The median duration of isolation in the hospital was 7 days. Conclusion : Large and chronic epidemic outbreaks of shigellosis have occurred in Jeju island. Throughout this survey, we could show the epidemiological characteristics and the nature of shigellosis in Jeju island. 목 적 : 2003년도에 제주도에서 발생한 세균성이질의 역학적 특성에 대하여 살펴보고 이를 통해 향후 세균성이질에 대한 예방 및 퇴치 방안을 강구코자 하였다.재료 및 방법 : 2003년 1월 1일부터 12월 31일까지 제주도에서 세균성이질에 감염된 것으로 확인된 환자들을 연구대상으로 하였다. 연구 방법은 분석 대상자에 대한 역학조사서 등의 문서화된 자료를 확보하였고, 미비한 정보에 대하여는 직접 환자를 방문하거나 전화를 해서 확인하였으며, 입원치료를 받은 도내 의료기관을 방문하여 의무기록조사를 수행하였다. 연구 분석은 대상자를 사건별로 3가지로 범주화하여 분석하였고 연령군 별로도 분석을 시도하였다. 각 군들 간의 역학적 특성의 비교분석을 위하여 카이 자승법, Fisher's 정확도 분석법, Kruskal-Wallis 통계법을 사용하였고, 1종 오류 5%에서 양측검정을 수행하였다. 결 과 : 2003년도에 제주도에서 발생한 것으로 보고된 세균성이질 환자는 총 99명이었으며, 이들 모두에서 S. sonnei가 동정되었다. 분석 결과 제주도에서의 세균성이질은 7세 미만의 영ㆍ유아에서 주로 발생하며, 성별로는 통계적으로 차이가 없었다. 일일 최대설사, 총 설사횟수, 설사 기간의 각각의 평균은 6.5회, 14.3회, 3.48일이었으며 연령이 낮을수록 일일 최대 설사, 총 설사횟수, 설사 기간이 더 많고 길었다. 의료기관 방문 시 주 호소증상으로는 무른 변(69.7%)이 가장 많았지만, 무증상도 15.2%를 차지하였다. 의료기관 방문시 첫 발현증상으로 가장 많은 것은 복통(43.4%)과 고열 (31.3%)이었으며 연령별로는 영ㆍ유아에서는 고열(50.0%)이, 취학생과 성인에서는 복통(70.0%, 43.9%)이 수위를 차지하였다. 세균성이질로 인한 병원에서의 격리기간은 평균 8.4일 정도이나 연령이 낮을수록 더 길어지는 양상을 보였다. 결 론:세균성이질은 제1군 법정 전염병으로 아직도 전국적으로 다수의 환자가 발생하며 특히 집단발생으로 인하여 공중보건학적인 문제를 야기하고 있는 실정으로 이번에 제주도에서 시행된 세균성이질에 대한 역학적 연구가 향후에 우리나라에서 발생할 세균성이질을 예측하고 관리하는데 도움이 될 것으로 생각된다.

Chronic administration of ketamine ameliorates the anxiety- and aggressive-like behavior in adolescent mice induced by neonatal maternal separation

신상엽,백남준,한승호,민선식 대한약리학회 2019 The Korean Journal of Physiology & Pharmacology Vol.23 No.1

Ketamine has long been used as an anesthetic agent. However, ketamine use is associated with numerous side effects, including flashbacks, amnesia, delirium, and aggressive or violent behavior. Ketamine has also been abused as a cocktail with ecstasy, cocaine, and methamphetamine. Several studies have investigated therapeutic applications of ketamine, demonstrating its antidepressant and anxiolytic effects in both humans and rodents. We recently reported that neonatal maternal separation causes enhanced anxiety- and aggressive-like behaviors in adolescent. In the present study, we evaluated how acute and chronic ketamine administration affected the behavioral consequences of neonatal maternal separation in adolescent mice. Litters were separated from dams for 4 hours per day for 19 days beginning after weaning. Upon reaching adolescence (post-natal day 35-49), mice were acutely (single injection) or chronically (7 daily injections) treated with a sub-anesthetic dose (15 mg/kg) of ketamine. At least 1 h after administration of ketamine, mice were subjected to open-field, elevated-plus maze, and resident-intruder tests. We found that acute ketamine treatment reduced locomotor activity. In contrast, chronic ketamine treatment decreased anxiety, as evidenced by increased time spent on open arms in the elevated-plus maze, and remarkably reduced the number and duration of attacks. In conclusion, the present study suggests that ketamine has potential for the treatment of anxiety and aggressive or violent behaviors.

기계경비시스템 운용현황 고찰과 운용품질개선 방안

신상엽 한국경호경비학회 2004 시큐리티연구 Vol.- No.8

This study has been conducted to provide data that contribute to increasing efficiency of 'Private Security', which is cooperated by customer, security companies and the police which carried out 'Public Law Enforcement' and controls security companies. To reach this purpose, we investigated the status of the 'Security Alarm Systems' operated by security service companied in Korea, analyzed arising problems, considered the polices for improving the operational quality. 'Electronic Security Systems' will increase working efficiency in performing 'Private Security'. There can be no two opinions on this matter. Therefore, it can be supposed that the improvement of operational quality of 'Electronic Security System' is an important factor to accomplish security services. 'Security Alarm System' is one of the 'Electronic Security System'. The critical problems in operating 'Security Alarm system' are unnecessary response by false alarm and nuisance alarm. To reduce the problems, it is suggested that security specialist officially licensed should improve security planning, installation and maintenance, and the 'Alarm Verification System' should be introduced with appropriate facilities.

타일 옆면파손의 방지대책에 관한 연구

신상엽,정의창,김영수 대한건축학회지회연합회 2007 대한건축학회연합논문집 Vol.9 No.3

As tiles are getting larger in size nowadays, interior ceramic tiles are often partly broken near joints and regularly cracked on the surface - Tile Side Breakage - after the attachment. In this study, large bathroom in real size was built to measure bond strength and ratio of length change, observe cracks and breakages with naked eye, and conduct the freeze-thaw experiment. Then, these factors were analyzed to identify the cause of Side Breakage and suggest the preventive measure. As a result, cement mortar enhances bond strength of the tile and resistance to cracks, and the more edges which is open, the more cracks tiles develop. Also, the installation of silicon expansion joints is considered as the most effective prevention method of Side Breakage.

왕겨의 소성온도와 평균입경에 따른 콘크리트의 강도특성에 관한 연구

신상엽,박문석,김용수 대한건축학회지회연합회 2007 대한건축학회지회연합회 학술발표대회논문집 Vol.2007 No.1

The purpose of this study is to investigate the effect of different levels of average particle size and firing temperature by rice husk ash on Admixture of high strength concrete. The experimental program included compressive strength of the concrete specimens. The specimens werw made with nomal portland cement and pozzolan materials with various replacement ratio and with W/B ratio fixed 0.35. The results indicate that Firing temperature 600℃, it was the maximum value by rice husk ash as admixture of high strength concrete. And It was maximum value particle size by rice husk ash as admixture of high strength concrete is 30㎛. The concrete mixed rice husk ash was quite improved, and thereafter the investigation the effect of different levels of average particle size and firing temperature by rice husk ash on Admixture of high strength concrete.

타일 옆면파손의 원인규명 및 방지대책에 관한 연구

신상엽,정의창,정유진,김영수 대한건축학회지회연합회 2006 대한건축학회지회연합회 학술발표대회논문집 Vol.2 No.1

A variety of flaws has been caused by a engineering method and an inappropriate selection of materials of building in carrying out tile-construction, which has been indicated to controversial problem on quality management of the tile construction and made construction companies and tile enterprises have an argument on that. In line with this, it is urgent that we should take a fundamental measure to reduce the flaws of the cracks by thoroughly investigating the cause of them. Therefore in this study, we would like to demonstrate a preventive measure of damage to the surface of the tile by making a model of a toilet, measure and analyze the conditions related to the quality management after the tile construction of the toilet according to experimental factor and it's level.

신경망 이론을 이용한 60MPa급 고강도 콘크리트의 배합설계모델에 관한 연구

신상엽,이유진,김영수 대한건축학회지회연합회 2014 대한건축학회연합논문집 Vol.16 No.3

본 연구는 배합설계 도출 시 시행착오적인 방법으로 낭비되던 시간과 노력을 최소화하기 위해 신경망 이론을 적용한 60MPa급 고강도 콘크리트 배합설계모델을 제시하고자 하였다. 완성된 배합설계모델을 통해 압축강도 및 단위 수량, 혼화재량을 예측하여 압축강도 시험을 실시한 후 목표값과 실측값을 비교함으로써 그 타당성을 검증하였다. 결론적으로, 신경망 모델의 정확도를 나타내는 결정계수(R2)가 배합설계 1의 압축강도를 예측한 모델은 0.99314, 배합설계 2의 압축강도를 예측한 모델은 0.96796으로 나타나, 신경망 모델의 학습이 비교적 올바르게 수행되었음을 알 수 있었다. 단위 수량과 혼화재량을 출력변수로 둔 배합설계모델의 검증실험 결과, 압축강도 목표값과 실측값의 오차율이 플라이 애시를 혼화재로 사용한 배합은 2%, 실리카흄을 혼화재로 사용한 배합은 1.83%로 나타났으며, 목표 압축강도 60MPa에 부합하는 배합 인자들의 적정 수준을 예측할 수 있었다.