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      • SCOPUSKCI등재

        궤양과 폐쇄성 황달을 동반한 십이지장 결핵

        손행종(Haeng Jong Sohn),전원호(Won Ho Jeon),윤윤보(Yoon Bo Yoon),최은수(Eun Soo Choi),김학산(Hak San Kim) 대한소화기학회 1994 대한소화기학회지 Vol.26 No.3

        The frequency and severity of intestinal tuberculosis have been significantly decreased due to the development of anti-tuberculosis chemotherapy, the preventive medicine, the vaccination and early detection of pulmonary tuberculosis. Among the gastrointestinal tract, the duode- num is one of site rarely involved by tuberculosis. It is very difficult to rnake a correct diagno- sis of duodenal tuberculosis, and even more difficult for its early diagnosis due to its non-spe- cific syrnptoms. Recently, the authors have experienced a case of duodenal tuberculosis pre- senting duodenal ulcer bleeding and obstructive jaundice due to tuberculous lymphadenitis. The patient was operated on for bleeding from a duodenal ulcer and the diagnosis was estab- lished at laparotomy by the presence of tuberculous (caseating) granulomas with epitheloid cells and multinucleated giant cells (horse shoe shape) of the duodenum and pancreaticoduo- lenal lymph nodes. And then, the patient improved following the administration of anti-tuber- culous chemotherapy. So, we report this case with a review of literature. (Korean J Gastroen- terol 1994; 26: 573 578)

      • SCOPUSKCI등재

        토끼에서 Trinitrobenzene Sulfonic Acid ( TNBS ) 로 유발시킨 급성 대장 손상에 대한Warfarin의 영향

        김학산,김동준,윤윤보,최은수,손행종(Haeng Jong Sohn),전원호(Won Ho Jeon),김광일 대한소화기학회 1994 대한소화기학회지 Vol.26 No.3

        N/A Inflammatory bowel disease is a group of chronic inflammatory disorders of unknown etiolo- gy involving the gastrointestinal tract. Wakefield et al suggested that Crohns disease is medi- ated by multifocal gastrointestinal infarction and recently Gaffney reported that marked im- provement in the patients with ulcerative colitis were noticed during treatment with heparin. This study was performed to find out, whether intrarectal infusion of TNBS 50mg into t.he rab- bit causes acute colitis or not, and whether warfarin pretreatment. Prevent.s colonic damage in duced by TNBS or not. The rabbits were randomly assigned to one of two groups, warfar in pretreated(N=6) and non treated(N=6). Warfarin solution was infused through the ear vein of the rabbit and TNBS 50mg was instilled into the colon of the rabbit. The rabbits were sacri ficed and the degree of colonic damage was recorded as visual analogue scale and microscopic findings. The results showed that intrarectal infusion of TNBS 50mg caused acut.e necrotic co litis, but warfarin pretreatment did not prevent TNBS induced acute colitis.(Korean J Gastro- enterol 1994; 26: 458 464)

      • KCI등재후보

        혈액투석 환자의 동정맥루 이환

        김인수(In Soo Kim),문석준(Seok Jun Moon),박현진(Hyun Jin Park),김동조(Dong Jo Kim),손행종(Haeng Jong Sohn),이무용(Moo Yong Rhee),박건욱(Keon Uk Park),최락경(Rak Kyeong Choi),유병희(Byung Hee Yu),문성수(Seong Soo Moon) 대한내과학회 1996 대한내과학회지 Vol.50 No.4

        N/A Objectives: The construction and maintenance of vascular access are essential in patients with end stage renal disease(ESRD) on chronic hemodialysis. So, the complications of vascular access are significant causes of morbidity and inadequacy of hemodialysis. The current study was undertaken to provide an estimate of the magnitude of the problem of access-related morbidity and to explore the relationship of sex, age, and underlying cause of renal failure as risk factors for vascular complications. Methods: We observed vascular access-related hospitalization, access complications, and sex, age, and underlying cause of renal failure as risk factors on 167 ESRD patients who have received maintenance hemodialysis between January 1983 and June 1993 at the National Medical Center. A univariate survival analysis of time to vascular access-related hospitalization was carried out for each of the risk factors under study, that is, sex, age, and underlying cause of renal failure. Kaplan-Meier survival curves were generated for categorized levels of each variable and compared using the log rank test. Results: 1) The vascular access-related hospitalization occupied 16.5% of all hospital stays and the mean length of hospital stays was 12.4 days. 2) The thrombosis occurred in 82.8% of all access complications. The formation of new vascular access was performed in 69.0% of vascular access-related morbidity. 3) The cumulative 1 year, 2 year, 3 year, 5 year, and 10 year survival rates of vascular access were 89.2%, 83.8%, 75.5%, 67.2%, and 53.2%, respectively, The cumulative survival rate of vascular access in women was lower significantly than in men. It was also lower significantly in diabetics than in other diseases including glomerulonephritis. But, age was not statistically correlated with vascular access survival. Conclusion: The complications of vascular access cause increase in hospitalization among ESRD patients, and women and diabetics apperar to be at particularly high risk. Additional studies on the risk factors for vascular access morbidity are needed to manage vascular access more carefully in ESRD patients on chronic hemodialysis.

      • SCOPUSKCI등재

        조기위암의 임상적 고찰

        김광일,최은수,조은경,김학산,서정일,손진희,손행종,전원호,윤윤보 대한소화기학회 1995 대한소화기학회지 Vol.27 No.1

        Background/Aims: Stomach cancer is the most common malignancy and one of the leading cause of death in Korea. However, the prognosis of early gastric carcinoma(EGC) has been reported execellent and this is why we emphasize the early diagnosis and treatment of gastric cancer. Methods: We analyzed 109 patients of early gastric carcinoma which had been confirmed by surgery and pathological examination from January 1986 to December 1992 in the National Medical Center. Resluts: The incidence of early gastric carcinoma was 18.5% of gastric resection for stomach cancer. Male to female ratio was 2.0:1 with male predominance. The commonly involved age of patients was 50 to 59 years and mean age was 55.2. The epigastric pain was predominant symptom and followed by epigastric discomfort and indigestion. The macroscopic classification revealed that the most common types were Ilc(31.9%) and its combined types(41.4%). In sixty cases(51.7%), the lesions extended to the submucosa, while fifty five cases(48.3%) were confined to the mucosa. The incidence of metastases to regional lymph nodes in mucosal carcinoma was in 8.9% and that of submucosal lesions was 28.3%(p$lt;0.05). The most commonly involved sites were antrum(60.3%) and lesser curvature(35.3%) of the stomach. Forty six cases(39.7%) were between 2.1 cm and 4.0cm in diameter and 15 cases less than 1cm. The most common pathologic type was tubular adenocarcinoma(82.8%), followed by signet ring ce11 carcinoma and mucinous adenocarcinoma. Overall 5 year survival rate for the entire group was 9l.6%. Conclusion: The clinical and pathologic features of early gastric carinoma in the National medical Center werc not much different from those of previous reports, except that the incidence was 18.5% in our series and higher than those of previous reports.

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