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이원식,정태훈,김교선,이국희,유덕종,손명원 대한내과학회 1986 대한내과학회지 Vol.30 No.2
The diagnostic value of transbronchial lung biopsy(TBLB) through fiberoptic bronchoscope was studied in 61 patients with diffuse or localized lung disease in which routine clinical and laboratory examinations revealed no diagnostic clue. By the technique adequate tissue specimen for diagnosis was obtainable in 28 of 33 patients (78.8 percent) and 25 of 28(89.3 percent) with localized and diffuse lung diseases, respectively. A histological diagnosis was possible in more than 75 percent of the patients with lung cancer proved by various means. On the other hand, in patients with tuberculous lesions, diffuse or localized, the incidence of positive diagnosis was less than a half. The complications among 61 patients underwent the TBLB were pneumothorax in one and hemoptysis in three, which subsided spontaneously. These facts suggest that the TRLB is a relatively safe, and more useful in the diagnosis of cancer of the lung than in inflammatory disease.
결핵 및 만성폐새성폐질환에 의한 폐성심의 환기력학의 차이
이원식,박희명,정태훈,김교선,유덕종,손명원 대한내과학회 1986 대한내과학회지 Vol.30 No.1
Ventilatory dynamics were studied in R2 cases of cor pulmonale caused by either chronic obstructive pulmonary disease(COPD) or far advanced pulmonary tuberculosis, with particular reference to differences in airways dysfunction between two groups. Ventilatory functions tested in this study were analyses of forced expiratory volume curves, maximal expiratory flow volume curves and determinations of closing volume with its ratio to vital capacity. The degree of airways obstruction as determined by the parameters derived from forced expiratory and maximal expiratory flow volume curves, observed and volume-adjusted, showed no significant difference between two groups, except for fast vital capacity which was significantly larger in the latter. The closing volume was significantly larger in patients with cor pulmonale due to COPD than in the other, hut its ratio to vital capacity showed no significant difference between two groups. Comparison of vital capacity and fast vital capacity in patients with COPD with and without cor pulmonale were insignificant. In contrast, these two parameters in patients with far advanced pulmonary tuberculasis with cor pulmonale were significantly smaller than in those without, and the degree of reduction in vital capacity in those with cor pulmonale was as much as 50 percent on the average. This suggests that in patients with pulmonary tuberculosis advanced to the extent to cause cor pulmonale is associated with destruction of approximately half of the lung tissues as reflected by vital capacity. The findings also suggest that in patients with cor pulmonale due to pulmonary tuberculosis, there is definite and considerable large and small airways obstruction similar to that in the other group, as well as restrictive ventilatory impairment.