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      • KCI등재

        단태 둔위분만에 관한 임상적 고찰

        서수형(SK Park),김복인(BI Kim),박성관(SK Park) 대한산부인과학회 1985 Obstetrics & Gynecology Science Vol.28 No.8

        Breech presentatiion is the most frequent abnormal presentation And excessive perinatal loss is asdsociated with brecch presentation and in large measure this loss in accounted for by prematurity congenital anomalies and birth traums In the endeavor to exert an effect on two of these problems cesarean section has been resorted to increasingly This study was analyzed the 375 singleton breech rpesentations among the total 9,267 deliveries retrospectively by the review of the charts which occrued during the period from January 1979 to December 1983 at In Je Medical College Pail Hospital in Seoul Department of Obstetrics and Gynecology and discussed the various aspects and diffculties in their managements This paper obtained the following results: 1. The incidence of the breech presentation was 4.05%(1:25) 2. The age distribution was mostly concentrated between the age of 26 and 30 (52.5%). 3. Incidence of the breech delivery by parity was 4.68% in primpara and 3.07 % in multipara. 4. As to gestational weeks, the frequency was mostly concentrated between 37 and 39 weeks (56.3%), and 31.7% between 40 and 42 weeks, 3.5% between 34 and 36 weeks, and less than 29 weeks, 2.9% between 29 and 33 weeks, and 2.1% in more than 42 weeks in orders. 5. the frank breech incidence was 33.3%, incomplete breech incidence was 28.8%, and complete breech incidence was 22.4%. 6. yearly cesarean section rate was from 55.1% to 75.4, and the mean was 67.5%. 7. Incidence of cesarean section by parity was 74.6% in primipara, 50.7% in first multipara, 45.8% in second multipara, and 37.5% in third multipara. 8. As to the birth weight, the frequency of cesarean section was mostly concentrated between 3,000 and 3,500gm(78.6), and 71.4% between 3,500 and 4,000gm 63.2% in more than 4,000gm, 67.0% between 2,500 and 3,000gm, and 56.3% between 2,000 and 2,500gm in orders, but none of the group less than 2,000gm. 9. As to the prognosis of the infants estimated by Apgar score, the depression rate of the infants by vaginal delivery was 6 times more higher than that of cesarean section delivery if the birth weight was over 2,000gm. 10. The perinatal mortality was 117.3/1,000, and the cause of death was prematurity, congenital anomalies, intracranial hemorrhage, entrapped aftercoming head, and cord prolapse in orders.

      • KCI등재

        항문괄약근에 발생한 자궁내막증

        조태호,서수형,차상헌,이지은,양정분 대한산부인과학회 1990 Obstetrics & Gynecology Science Vol.33 No.8

        저자들은 본원에서 항문괄약근의 자궁내막증 1례를 경험하였기에 간단한 문헌고찰과 함께 이에 보고하는 바이다. Endometriosis is a disease of unknown etiology. It has been known that it might cause dyspareunia, premenstrual spotting, luteal phase defect, dysmenorrhea, and infertility. We found endometriosis of the anal sphincter which occured after posterior colporrhaphy on the perineum, and it is known to be very rare. Now, We present a case of endometriosis of the anal sphincter with a brief review of the literature.

      • KCI등재

        Platinum 제제를 기본으로 한 치료에 실패한 재발성 혹은 난치성 난소암 환자의 구제요법으로서 Taxol-Carboplatin요법의 효용성에 관한 연구

        배동한,서수형,장경택,강준모,장진영 대한산부인과학회 1998 Obstetrics & Gynecology Science Vol.41 No.9

        1995년 3월부터 1997년 3월까지 순천향대학교 천안병원 산부인과에서 수술받은 후 난소암으로 진단되어 Platinum 제제를 기본으로 한 항암화학요법 후 재발하거나 치료에 실패한 환자들을 대상으로 Taxol-Carboplatin제제를 투여한 후 치료반응 및 부작용을 평가하여 다음과 같은 결과를 얻었다. 1. 대상 환자는 12명이었고 이 중 1명(8%)이 완전반응, 2명(17%)이 부분반응을 보여 전체 반응률은 25%(3/ 12)이었다. 2. Grade 4의 백혈구 감소증이 전체 Taxol-Carboplatin 제제 치료 경과 중에 16%에서 나타났고 Grade 3는 41% 에서 보여 이들에게는 G-CSF를 주사하여 치료를 계속할 수 있었다. Grade 3 이상의 빈혈은 없었고, Grade 3 이상의 혈소판 감소증은 3%에서 보였고, Grade 2 소화기계 부작용은 3%이었으며 Grade 3 이상의 소화기계 부작용은 보이지 않았다. 이상의 결과로 볼 때 Taxol-Carboplatin 제제의 난치성 혹은 재발성 난소암에서 Platinum 제제를 기본으로 한 화학요법 후 재발하거나 치료에 실패한 환자들의 일부에 서 유용한 치료법으로 사용될 수 있으리라 사료된다. 그러나 장기적인 생존율의 개선은 아직도 미미한 편으로 향후 Taxol을 기본으로 한 병합화학요법의 개발, 복강내 주입법, G-CSF 및 자가골수이식술을 이용한 Taxol의 고용량요법, 수술 후 일차 화학요법으로서 Taxol의 효용성에 대한 연구와 새로운 치료제의 개발을 위한 지속적인 연구가 필요할 것으로 사료된다. The purpose of this study is to assess the efficacy and toxicity of Taxol used as a salvage therapy in patients with recurrent or drug-refractory ovarian cancer. Nonrandomized, clinical trial of patients with recurrent or drug-refractory ovarian cancer. recurrent ovarian cancer was undertaken. Twelve patients aged 35∼71 years (median 61) with recurrent or drug-refractory ovarian carcinoma were given Taxol-containing regimen. Taxol was administered at a dose of 175 mg/m2. intravenously with Carboplatin (400 mg/m2) every 21 days. The median treatment cycle was 5.4 cycles (range, 3 to 9 cycles). A premedication regimens (Dexamethasone 40mg # 2 IM, Diphenhydramine 50 mg Ⅳ, Cimetidine 300 mg Ⅳ) were used to avoid acute hypersensitivity reactions. The response of patients were evaluated with tumor markers (CA-125, CEA) and CT or MRI before and after chemotherapy. Responses and toxicities were defined according to the Gynecologic Oncology Group (GOG) criteria. The overall response rate was 25% (3/12), including 1 complete response (CR) and 2 partial response (PR). The most common severe toxicity was leukopenia, with grade 2 toxicity ocurring in 65% of the courses; grade 4 leukopenia occuring in 16% of the courses. Other hematologic toxicities were anemia and thrombocytopenia, but no grade 4 these severe toxicities were noted. We observed 25% response rate with taxol for patients with drug-refractory or recurrent ovarian cancer. Taxol is the active drug in advanced ovarian cancer, numerous reports of unequivocal antineoplastic effect of Taxol, but has limited role in refractory or relapsing cases. Further study is required to evaluate the optimal dose of Taxol or combination with other agent in the management of advanced ovarian cancer.

      • KCI등재

        만삭임부에서 발견된 병합임신 1 예

        배동한,신영우,조태승,서수형,이창희 대한산부인과학회 1993 Obstetrics & Gynecology Science Vol.36 No.3

        결론적으로 병합임신은 날로 증가되는 추세에 있고 또 산모와 태아에게 동시에 매우 위험한 결과를 야기시킬 수 있으므로, 전형적이지 않은 양상의 다태임신이나 자궁외임신 또는 유산 의 경우에서는 항상 이의 가능성을 염두에 두어 조기진단 및 치료가 필요하다고 생각되며, 조기에 정확히 진단함으로써 개복수술로 자궁외임신을 제거하여 파열 및 복강내 출혈을 방지하여 모성 이환율 및 사망율을 감소시키고 자궁내 태아의 생존율을 높일 수 있다. 최근에 본원에서는 만삭임부의 제왕절개수술시 우연히 발견된 난관 팽대부위의 자궁외임신 병소는 기왕출혈과 응고된 임신성 탈락막 주위에 태낭과 배태(embryo)가 괴사된 소견을 보임 으로써 건성괴저(mummification)가 된 것으로 자궁내 병합된 정상 임신만이 만삭까지 발육성장되고 좌측 난관팽대부 임신부위는 임신 전반기 3개월이전에 발육이 중지되어 건성괴저가 일어난 매우 희귀한 경우로 사료되어 간단한 문헌고찰과 함께 보고하였다. While ovulation is recently induced with clomiphene citrate, HCG and HMG, the incidence of simultaneous intrauterine and extrauterine pregnancies is increased concurrently. The incidence of combined pregnancy associated with ovulation inducing drugs is ascertained. During cesarean section of term pregnant woman who underwent in vitro fertilization left tubal mass was found and turned out to be ectopic pregnancy histopathologically after salpingectomy. Ina review of the world`s literature on combined intrauterine and extrauterine pregnancies only 13 cases reached term and were delivered and the infants survived the neonatal period.

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