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변상현 中央醫學社 1989 中央醫學 Vol.54 No.11
2 days old male neonate with micrognathia and cleft palate was presented.: He had difficult respiration and sucking failure. A brief review of literature was made.
다중 스케일 특징 맵을 사용한 인코더-디코더 네트워크 기반 대비 개선
변상현,임헌성,유수환,백준기 대한전자공학회 2020 전자공학회논문지 Vol.57 No.5
The paper presents a contrast image enhancement algorithm based on an encoder-decoder network. The proposed method consists of three steps: i) multi-scale feature map generation from an input low-contrast image, ii) contrast enhancement based on the encoder-decoder network, and iii) detail reconstruction network. The proposed method effectively prevents color distortion by combining the multi-scale feature maps generated from the input image while enhancing the contrast using the encoder-decoder network. Besides, the detail reconstruction network restores the edges and textures lost in the compression layers of the encoder-decoder network. Experimental results show that the proposed method can provide the contrast-enhanced result without brightness saturation and color distortion than existing contrast enhancement methods. 본 논문에서는 인코더 디코더 네트워크를 기반으로 대비 영상 개선 알고리듬을 제안한다. 본 알고리듬은 크게 세 단계로 구성된다: i) 다중 스케일 입력 영상을 이용한 특징 맵 생성, ii) 인코더-디코더 기반의 네트워크를 사용하여 압축과 복원을 통한 대비 개선, iii) 대비 개선에서 소실된 디테일을 복원하기 위한 네트워크. 제안하는 방법은 인코더-인코더 방식으로 대비를 개선시키는 것과 동시에 입력 영상에서 생성되는 다중 스케일 특징 맵을 결합함으로써 효과적으로 색상 왜곡을 방지한다. 디테일 복원 네트워크는 인코더-디코더 네트워크의 특징 맵 압축 과정에서 손실된 디테일 성분을 복원한다. 실험결과는 제안하는 방법이 기존의 대비 개선 방법들 보다 신호 포화 현상, 색상 왜곡이 없는 개선된 결과 영상을 제공할 수 있음을 보인다.
변상현 충남대학교 의과대학 지역사회의학연구소 1995 충남의대잡지 Vol.22 No.2
I analyzed 9 amino acids of urine of 75 healthy newborn who were born at Chungnam National University Hospital and fed with artificial cow milk from September 1993 to September 1995. Cystine and tryptophan were analyzed in 49 cases, and tyrosine, valine, leucine, lysine, methionine, isoleucine and phenylalanine were in 75 cases. Lysine was detected at 59 %, but tryptophan was not detected at all. The biggest normal range was shown in cystine and the norrowest was in leucine.
신생아 패혈증의 조기 진단에서의 APR 점수의 의의에 관한 연구
변상현 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2
To evaluate the significance of APR(acute phase reactants) score in the early diagnosis of neonatal sepsis, I measured APR score using APR-DR kit by MBL in Japan and performed blood culture for bacteria, total WBC count and platelet count in the peripheral blood of 22 sepsis neonates who were clinically diagnosed and 42 healthy neonates from Mar. 1993 to Oct. 1993 at Chungnam National University Hospital NICU. Results are as follows. 1. The incidence of sepsis was large significantly in the group whose APR score was over 1 than the group whose APR score was less 2.(p<0.01) 2. In sepsis patients, the blood culture positivity was large significantly in the group whose APR score was over 1 than the group whose APR score was less 2.(p<0.01) 3. WBC count and platelet count in peripheral blood did not have any value in the early diagnosis of neonatal sepsis.
급성 림프구성 백혈병 환아의 말초혈액 T-림프구 아형과 림프구 증식능의 의의에 관한 연구
변상현,서종진,정용헌 충남대학교부설 생명공학연구소 1991 생물공학연구지 Vol.1 No.-
To evaluate the relationship between peripheral blood T-lymphocyte subsets, mitogen-induced lymphocyte proliferation and the outcome of acute lymphoblastic leukemia in childhood, the authors studied 15 cases of acute lymphoblastic leukemia in childhood. The results were as follows: 1) Percent peripheral lymphocyte and percent CD8+ cells showed no significant difference between total patient group and control group, while percent CD4+ cells was significantly decreased in total patient group compared to control group. But no significant difference was found between patient subgroups. 2) Total counts of CD4+ cells and CD8+ cells showed no significant difference between patient subgroups. 3) The ratio of CD4+ cells and CD8+ cells showed no significant difference between patient subgroups, but more cases with the ratio less than 1.0 were found among total patient group compared to control group. 4) The stimulation indices of PHA and Con-A were significantly decreased in total patient group (p<0.05, p<0.005) compared to control group, but no significant difference was observed between patient subgroups. 5) The unstimulated ^3[H]-thymidine uptake showed no significant relationship between patient subgroups. 6) The distribution of T-lymphocyte subsets showed no significant relationship with the stimulation index of PHA and Con-A. These results showed that the children with acute lymphoblastic leukemia have depressed cellular immune functions tested with T-lymphocyte subsets and mitogen-induced lymphocyte proliferation assay. But these results can not be regarded as one of prognostic factors of acute lymphoblastic leukemia in childhood unless there are additional longterm data indicating the T-cell mediated immune functions are related to the outcome of acute lymphoblastic leukemia in childhood.
변상현 충남대학교 의과대학 지역사회의학연구소 1997 충남의대잡지 Vol.24 No.1
I analyzed 13 acute renal failure premature infants from March to November, 1997. The results were shown that prognosis of nonoligouric ARF patients were grave and had a tendancy of hyperpotassemia than oligouric ARF patients.
변상현 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1
Author studied the correlation between arterial and capillary blood gas analysis in 30 neonates cared in neonatal ICU. Samples were collected from arterial and capillary site at the same time. And analyzed with Nova Biochemical Company, Stat profile ultra. Author found that there are no differences in Base excess, CO_2, HCO_3, pH but no reliabilities in 0_2, SO_2 between arterial and capillary blood.
특발성 호흡곤란 증후군(Idipathic Respiratory Distress Syndrome)에서 Surfactant 보충요법의 단기적 결과
변상현 충남대학교 의과대학 지역사회의학연구소 1992 충남의대잡지 Vol.19 No.2
Surfactant replacement therapy had accomplished to 12 IRDS patients and I got a conclusion that surfactant treatment improve the clinical symptoms, signs, arterial blood oxygenation and chest X-ray findings of IRDS. But the total mortality rate was not decreased compared to control. And the major problem that I have to solve are to improve the general treatment of IRDS and to establish the concept of post-surfactant changes of the patients. Then it will give more chance to save the life of IRDS patients.