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배상도,이승재,박효일,허곤 인제대학교 1980 仁濟醫學 Vol.1 No.2
대부분의 악성종양은 뇌 혹은 경막으로 전이할 수 있다. 그러나 갑상선종양 자체는 그렇게 희귀한 것이 아니나 뇌나 경막으로 전이하는 경우는 드물다. 본교실에서는 우측두정부에 전이를 일으킨 갑상선종양을 경험하고 문헌고찰과 함께 보고하는 바이다. Any maligant neoplasm is capable of metastasis to the brain or meninges. But thyroid cancer is known to hardly involve the cranium even although the incidence of thyroid cancer is relatively high as compared with that of malignant neoplasm of other endocrine structures. The authors have experienced a case of metastatic thyroid cancer on right parietal bone. The available literature regarding these tumor is reviewed.
간내 담석 수술 후 재발에 영향을 미치는 인자에 대한 연구
배상인(Sang In Bae),유희철(Hee Chul Yu),조백환(Baik Hwan Cho) 한국간담췌외과학회 2010 한국간담췌외과학회지 Vol.14 No.2
Purpose: Hepatolithiasis, which is located in proximal sites of the common hepatic bile duct, is a common disease in Korea. Hepatectomy is a more effective treatment for achieving complete removal of stones and biliary strictures. However, the incidence of remnant or recurrent stones is still high. The aim of this study was to evaluate factors related to the recurrence of stones after surgical treatment of hepatolithiasis. Methods: From February 1999 to February 2009, we conducted a retrospective study of case records of 208 patients who underwent operations for hepatolithiasis at the Department of Surgery, Chonbuk National University Hospital. Results: The male to female ratio was 1:1.97; the mean age was 55 years. Hepatolithiasis was located in the left intrahepatic duct in 69.7% of patients, in the right intrahepatic duct in 14.4%, and in both ducts in 15.9%. Operative procedures were as follows: left lateral sectionectomy in 109 (52.4%), left hemihepatectomy in 26 (12.5%), posterior sectionectomy in 5 (2.4%), a right hemihepatectomy in 8 (3.8%), a choledocholithotomy in 38 (8.6%), a choledocho-enterostomy in 18 (8.6%), a choledochotomy in 1 (0.46%), a choledochal cyst excision in 1 (0.46%), and no primary operation in 2 (0.9%). Complete stone clearance was achieved in 76% after operative treatment. Biliary stricture was significantly associated with remnant stones (p=0.000). In addition, the incidence of recurrent stones was 15.3%. Recurrent stones were associated with biliary stricture (p=0.001), hepatectomy (p=0.003), and bilateral location of stones (p=0.016). During the follow up period, the mortality rate related to operative treatment was 0.96%. Conclusion: Biliary stricture, hepatectomy, and bilateral location of stones are associated with recurrent hepatolithiasis after surgery.
배상수,Bae, Sang Soo 한국농촌의학지역보건학회 2012 농촌의학·지역보건 Vol.39 No.4
The New Public Health(NPH) is a comprehensive approach to protecting and promoting the health status of each individual member and society as a whole. NHP is not so much a philosophy to broaden the understanding of public health as it is an action plan to address current public health system. This paper's objectives include increasing public and professional awareness of the significant changes in the national public health systems of developed countries and contributing to more effective delivery of public health services in Korea. This paper reviews articles and documents concerning NPH and the public health system, and outlines of the achievements in developed countries since NPH movement began. These include the change in the definition and function of public health, expansion of public health networks, strengthening of public health policy, reorientation of public health delivery systems, promotion of workforce capacity, and the implementation of evidence-based management. To overcome the challenges facing the public health system of Korea, we must prioritize the value of population-based approach, expand the notion of a public health system to encompass all sectors that can influence health, promote a "Health in All Policies" approach, focus on an evidence-based health policy and program, develop core competencies for public health workers, and establish performance standards for public health organizations based on the core functions of public health.
배상병,김현정,이상철,김찬규,이남수,이규택,박성규,원종호,홍대식,박희숙 순천향의학연구소 2008 Journal of Soonchunhyang Medical Science Vol.14 No.2
Autologous peripheral blood stem cell transplantation (APBSCT) with high dose chemotherapy could be converted into prolongation of remission and of survival in multiple myeloma patients. From May 2003 to November 2006, We are retrospectively analysis of 13 patients with newly diagnosed multiple myeloma who received APBSCT with high dose therapy at Soon Chun Hyang Bucheon hospital. VAD(vincristine, adrimycin, dexamethasone) or VAMP(vincristine, adriamycin, methylprednisolone) was used to induction chemotherapy regimen. Cyclophosphamide and melphalan was respectively used as mobilization and conditioning regimen. The median age at the time of diagnosis was 55 years(range;40-67) with male sexual predominance(M:F=8:5). Most of patients(12/13,92%) were diagnosed with stage III(Durie-Salmon staging system). Tandem transplantation was eight patients. Overall response rate to induction chemotherapy and ASCT were 85% (CR; 31%, PR; 54%) and 100% (CR; 69%, PR; 31%), respectively. Median event free survival and overall survival after ASCT was 28.2 months and 35.6 months. In univariable analysis, there was no significant difference in the Ig isotype(Ig G vs Ig A), hemoglobin(below 8.5 vs above 8.5 g/dL), creatinine(below 2 vs above 2 mg/dL), LDH(below 400 vs above 400 IU/L), chromosomal abnormality(normal vs abnormal), frequency of transplantation(single vs tandem), but 2-microglobulin(below 4 vs above 4 mg/dL) was significant difference (log-rank ; p=0.014) for the median duration of overall survival. Although the number of patients was small and follow up duration was short in this study, APBSCT with high dose chemotherapy was effective and feasible in patients with newly diagnosed multiple myeloma. 2-microglobulin also can be a potent prognostic factor of APBSCT in multiple myeloma for overall survival.