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Sporadic Creutzfeldt-Jakob Syndrome Misdiagnosed as Recurrent Stroke: A Case Report
배민준,강인현,Yangrok Hur,Ki Hun Hwang 대한노인병학회 2021 Annals of geriatric medicine and research Vol.25 No.2
While sporadic Creutzfeldt-Jakob disease (sCJD) typically presents with neurological symptoms such as cognitive impairment, ataxia, and myoclonus, its clinical manifestations can be diverse. We report about a 70-year-old woman with sCJD who was misdiagnosed with recurrent stroke. She initially showed hemiplegia and high-intensity signals on brain diffusion-weighted magnetic resonance imaging (DWI), which corresponded to the symptoms of a stroke. She was diagnosed with recurrent stroke as her muscle weakness showed stepwise deterioration, with the appearance of additional high-intensity signals on brain DWI. Several days later, she developed Broca’s aphasia, cognitive impairment, and myoclonus in the right upper and left lower extremities. Brain DWI showed high-intensity signals in the cortex, caudate nucleus, and putamen. Therefore, sCJD was suspected; she subsequently underwent further evaluation and was diagnosed with sCJD. The findings of this case indicate that sCJD can have a clinical course similar to that of recurrent stroke.
Dysphagia due to Physiological Constriction after Stroke: A Case Report
배민준,강인현,Yangrok Hur,황기훈 대한연하장애학회 2021 대한연하장애학회지 Vol.11 No.2
The aortic arch normally causes no symptomatic physiological constriction of the esophagus. Symptoms of dysphagia are generally observed in the presence of specific conditions, such as an aortic aneurysm. In the present case, during a videofluoroscopic swallowing study (VFSS), the authors incidentally found that despite the absence of an aortic lesion, the dysphagia observed in a stroke patient was caused by compression from the aortic arch. The patient complained of discomfort when swallowing, similar to a bolus lodged in the chest, which was consistent with compression by the aortic arch found on the VFSS and chest computed tomography (CT). After undergoing dysphagia therapy, the VFSS after 52 days revealed improved swallowing function; however, the sensation of food lodging in the chest due to compression by the aortic arch persisted. We conclude that although the physiological constriction of the esophagus by the aortic arch is usually asymptomatic, the constriction can be a factor that exacerbates the swallowing function in patients with dysphagia, and should therefore be considered during the differential diagnosis.
재활용 플라스틱 펠렛과 벨벳콩(Mucuna pruriens) 추출물의 항산화 효능 상관관계 검증
한동근,배민준,갈격,김현정,김세기,안봉전 사단법인 대한화장품학회 2023 대한화장품학회지 Vol.49 No.1
In this study, the correlation between recycled plastic pellets and the antioxidant efficacy of the extract of Mucuna pruriens (M. pruriens) was verified. After immersing recycled plastic pellets in M. pruriens extracts, they were stored for 30 days under various temperature conditions, and then analyzed for DPPH radical and ABTS+ radical erasing ability, SOD-like activity, total phenol and flavonoid content. Compared to the existing efficacy, DPPH radical elimination showed less than 30% activity change in ECOTRIA and PCR-PP pellets, and the largest decrease in activity of 46.06% was confirmed in Grico pellets. As a result of measuring ABTS+ radical erasure ability, less than 5% of efficacy change was confirmed in all pellets. As a result of measuring SOD-like activity, all showed a decrease in activity of more than 30%, and as a result of measuring the total phenol and flavonoid content, all pellets showed a tendency to decrease compared to the existing content. Through this results, it was confirmed that the physiological activity of M. pruriens extract decreased and changed by recycled plastic pellets, and based on the results of this study, recycled plastic pellets are believed to affect the existing efficacy and activity stability of M. pruriens extract. 본 연구에서는 재활용 플라스틱 펠렛과 벨벳콩(Mucuna pruriens) 추출물의 항산화 효능 안정도에 대한상관관계를 검증하였다. 재활용 플라스틱 펠렛을 벨벳콩 추출물에 침지 시킨 다음 다양한 온도 조건에서 30 일간 보관한 후 DPPH radical 및 ABTS+ radical 소거능, SOD 유사 활성, 총 페놀 및 플라보노이드 함량 분석을실시하였다. 기존 효능에 대비하여 DPPH radical 소거능은 ECOTRIA, PCR-PP 펠렛에서 30% 미만의 활성변화를 나타내었으며, Grico 펠렛에서 46.06%의 가장 큰 활성 감소가 확인되었다. ABTS+ radical 소거능 측정결과, 모든 펠렛에서 5% 미만의 효능 변화가 확인되었다. SOD 유사 활성을 측정한 결과, 모두 30% 이상의활성 감소를 나타내었으며, 총 페놀 및 플라보노이드 함량 측정 결과, 모든 펠렛에서 기존 함량 대비 감소하는경향을 나타내었다. 이를 통해 재활용 플라스틱 펠렛에 의한 벨벳콩 추출물의 생리활성 감소 및 변화를 확인하였으며, 본 연구 결과를 토대로 재활용 플라스틱 펠렛은 벨벳콩 추출물이 지닌 기존 효능 및 활성의 안정도에영향을 미치는 것으로 판단된다.
Self-Knotting of Nasogastric Tube in a Stroke Patient with Dysphagia: A Case Report
강인현,배민준,Yangrok Hur,황기훈 대한연하장애학회 2020 대한연하장애학회지 Vol.10 No.2
In cases of inadequate nutrition among individuals with dysphagia, nasogastric tube insertion is considered for nutritional supplementation. Typically, the complications of nasogastric tube insertion are not severe. In rare cases, however, nasal or nasopharyngeal injury caused by the self-knotting of nasogastric tubes can occur. This paper presents a case of spontaneous knotting of a nasogastric tube and its removal in a patient with aspiration pneumonia caused by dysphagia. This case shows that self-knotting must be considered when there is strong resistance during the removal of a nasogastric tube.
Neuralgic Amyotrophy of the Lower Extremity in a Neuropsychiatric Patient: A Case Report
문원식,모상준,배민준,황기훈 대한근전도전기진단의학회 2018 대한근전도 전기진단의학회지 Vol.20 No.2
Neuralgic amyotrophy (NA) is an idiopathic disease characterized by muscular atrophy accompanied by neuralgia, where acute pain in the limb, mostly including the shoulders, leads to muscle weakeness and atrophy in the limb days to weeks after the onset of pain. Although its exact pathogenesis is unknown, genetic and nongenetic factors, such as infection, surgery, and trauma are suspected contributors. We report this case as we diagnosed NA of the right lower limb via enhanced MRI as well as EMG and have followed up the patient’s prognosis and radiologic changes for one and a half years. In addition, the patient had been diagnosed with neuropsychiatric disorders, such as major depressive disorder and somatic symptom disorder.
벨벳콩(Mucuna pruriens) 추출물의 항산화 효능 검증
박남완,한동근,갈격,배민준,김현정,김세기,최은영,안봉전 사단법인 대한화장품학회 2023 대한화장품학회지 Vol.49 No.1
In this study, we tried to verify the value of the use of Mucuna pruriens (M. pruriens) extract as an antioxidant functional cosmetic material based on natural materials. After extracting, concentrating, and freeze-drying M. pruriens with water, 70% ethanol, and 70% acetone as solvents, samples of powdered hydrothermal extract (MW), 70% ethanol extract (ME), and 70% acetone extract (MA) were prepared. As a result of analyzing antioxidant activity through DPPH radical scavenging activity, ABTS+ radical scavenging activity, SOD-like activity, reduction ability, total phenol and flavonoid content analysis using MW, ME, and MA, all showed excellent antioxidant effects. Therefore, it is believed that M. pruriens extract is highly likely to be used as a natural material for antioxidant-related functional cosmetics. 본 연구에서는 벨벳콩(Mucuna pruriens, M. pruriens) 추출물을 활용하여 천연소재 기반 항산화 기능성화장품 소재로서의 활용가치를 검증하고자 하였다. 벨벳콩을 물과 70% 에탄올, 70% 아세톤을 용매로 하여 추출, 농축, 동결건조한 다음 각각의 분말화된 벨벳콩 열수 추출물(MW), 벨벳콩 70% ethanol 추출물(ME), 벨벳콩70% acetone 추출물(MA) 시료를 확보하였다. MW, ME, MA를 활용하여 DPPH 라디칼 소거 활성, ABTS+ 라디칼소거 활성, SOD 유사 활성, 환원력, 총 페놀 및 플라보노이드 함량 분석을 통해 항산화 활성을 분석한 결과, 모두 우수한 항산화 효능을 나타내었다. 따라서 벨벳콩 추출물은 항산화 관련 기능성 화장품 천연소재로서의활용 가능성이 높을 것으로 사료된다.
자율주행 소프트웨어의 신뢰성 향상: 주행 안전에 관한 연구
안재준 ( An Jae Jun ),배민준 ( Bae Min Jun ),이시우 ( Siwoo Lee ),전재욱 ( Jaewook Jeon ) 한국정보처리학회 2023 한국정보처리학회 학술대회논문집 Vol.30 No.2
본 연구에서는 실시간 자율주행 프로그램의 안정성 향상 방안을 제안한다. 안정성을 해치는 요소에는 조도의 변화, 노면의 불규칙성, 제어 신호의 딜레이가 있다. 이를 해소하기 위해 여러 이미지 처리 필터, ROI 의 축소, Lookuptable 을 제안한다. 이를 통해 보다 안정적인 자율주행을 구현한다.