小兒의 Cushing氏 症候群 1例

朴昌潤(C.Y. Park),李敏雄(M.W. Lee),金相哲(S.C. Kim),申澤秀(T.S. Shin) 대한외과학회 1977 Annals of Surgical Treatment and Research Vol.19 No.7

根源不明 轉移性 頸部癌의 治療

金寊,彦(G.E. Kim),徐昌玉(C.O. Suh),朴昌潤(C.Y. Park),朴正秀(C.S. Park),閔辰植(J.S. Min) 대한방사선종양학회 1984 Radiation Oncology Journal Vol.2 No.1

Guidelines for the optimal management of patients with cervical cancerous nodes from an unknown primary site, has not been yet settled. However, radical treatment has been advocated employing either a surgery, or radiotherapy, or combination of the two in relation to the location, stage and histologic features of nodes in the neck. Of 43 patients who presented with "Cervical metastases from an unknown primary" since 1971, 31.2% survived 3 years after adequate management. Combined modality with surgery and radiation showed more favorable treatment results: in local control rate, 3 year survival rates and the subsequent apperances of the contralateral side of neck node through the retrospective analysis. In 11 cases, the primary tumors became apparent later, carcinoma of the hypopharynx, being the most frequent site, rather than the nasopharynx.

간암의 (肝癌) 초음파 (超音波) 소견

오기근(K K Oh),박창윤(C Y Park),최형식(H S Choi),문영명(Y m Moon) 대한소화기학회 1984 대한소화기학회지 Vol.16 No.1

N/A Ultrasonographies of hepatoma were performed in 61 cases and among them RI scintiscans were obtained in 39 patients. Authors analyzed and compared findings of ultrasonography and RI scan of primary hepatoma in that 39 cases. The results were as follows: 1) The sex ratio was 3.4: 1 male predominance and the age showed high incidence in 6th and 7th decades. 2) Ultrasonographic findings of hepatoma were classified into 4 types as solitary, multinodular, multiple and diffuse. The most common type was solitary. The location of lesions was prevalent in right lobe of liver(59%) and most hepatoma(92%) were larger than 5 cm suggesting all advanced hepatomas in our cases. Echogenic and well marginated echo pattern is frequent and sometimes central necrosis(21%). 3) Liver scintiscan was fairly helpful in detecting the functionless cold area in our studies. Although, ultrasonography is more useful in detecting the nature of lesions and its characteristics and other associated anatomic relationship of sonographic findings such as ascites, splenomegaly, abnormality in portal venous system and hepatic biliary system.

370 KHz에서 고온 초전도 안테나를 적용한 무선전력전송 시스템의 동작특성 조사

정윤도(Y. D. Chung),김충섭(C. S. Kim),윤원근,허민욱(M. W. Hur),박창윤(C. Y. Park),조문형(M. H. Cho),김대욱(D. W. Kim),김태중(T. J. Kim),임성우(S. W. Yim),고태국(T. K. Ko) 대한전기학회 2014 대한전기학회 학술대회 논문집 Vol.2014 No.7

乳房에 寄生한 Sparganum mansoni 1例 報告

鄭巴琮(P. J. Jung),兪炳旭(B. O. Yoo),朴昌潤(C. Y. Park),丘範煥(B. H. Koo) 대한외과학회 1981 Annals of Surgical Treatment and Research(ASRT) Vol.23 No.3

우리나라 폐암의 방사선 요법에 대하여

박창윤,김귀언,조관호 한국의학사 1984 診斷과治療 Vol.4 No.7

^(169)Yb-DTPA를 이용한 Cisternography

도종웅,김상철,이규창,이헌재,양병철,박창윤,최병숙 대한신경외과학회 1977 Journal of Korean neurosurgical society Vol.6 No.1

The radioactive nucleid cisternography is being used as a diagnostic adjunct of CSF rhinorrhea and otorrhea, hydrocephalus, patency after ventricular shunt operation, brain tumor and cangenital anomalies of the central nervous system. In numerous radioactive nucleids, ^(169)Yb-DTPA is known to have moderately effective half life, high energy level for scintilation, and pure r-emitter in subarachnoid space. Authors review some clinical advantage of cisternography using ^(169)Yb-DTPA applied in the diagnosis of CSF rhinorrhea and otorrhea, hydrocephalus, CSF fistula and patency after ventricular shunt operation.

간질환에서의 혈청 Carcinoembryonic Antigen 가

박창윤,최규옥,김기황 대한핵의학회 1978 핵의학 분자영상 Vol.12 No.2

1) 1978년 10월부터 12월까지 세브란스병원 동위원소실에 내원하여 간 주사상 이상 소견이 있었고 후에 간질환이 확진된 58명의 환자의 질환별 분포는 간경화가 19명, 간암이 18명, 만성 활동성 간염이 7명, 급성 바이러스성 간염이 5명, 간농양이 3명, 폐쇄성 황달이 3명, 기타 외상성 간혈종, 횡경막 하농양과 간디스토마증이 각기 1례였다. 2) 질환별 CEA가의 증가는 다음과 같다. 간경변 19례증 13례(68.4%), 간암 18례중 5례(27.8%), 만성 활동성 간염 7례중 5례(71.4%), 급성 바이러스성 간염 3례중 1례(20%), 간농양 3례 전례(100%), 폐쇄성 황달 3례중 2례(66.7%), 기타 외상성 간혈종, 횡경막하 농양 간디스토마증은 모두 정상가를 보여 주었다. 3) 간경변 환자 19명을 대상으로 한 간 기능검사인 Bilirubin, Alkaline Phosphatase SGOT, Prothrombin time과 CEA가의 관계는 직선상관관계가 없었다. Carcinoembryonic antigen was initially known as tumor specific antigen and had a potential diagnostic value in the detection of digestive tract malignancies. However, subsequent studies showed CEA and CEA-like antigen present inbenign disease, particul1ary in liver. We had collected sera from 58 patients who had liver scan and later were diagnosed clinically and histologically as liver disease. We estimated CEA values and correlations were made with liver function tests in liver cirrhosis cases. The results: 1) The raised plasma carcinoembryonic antigen level were found in 13 (68.4%) of 19 patients cirrhosis, 5(27.8%) of 18 patients in hepatoma, 5(71%) of 7 patients in chronic active hepatitis, all 3 patients in liver abscesses, 2(66.7%) of 3 patients in liver ablscesses, 2(66.7%) of 3 patients in obstructive biliary disease and none in each one patient of traumatic liver hematoma, subphrenic abscess and clonorchiasis. 2) There is no linear correlation between carcinoembryodic antigen leveland liver function tests including serum bilirubin, alkaline phosphatase, SGOT and prothrombin time in liver patients.

성장홀몬과 내분비계 질환

박창윤,최규옥,김기황,허갑범,유경자,이혜리,손희영 대한핵의학회 1979 핵의학 분자영상 Vol.13 No.1

1976년 1월부터 1979년 3월까지 연세대학교 부속 세브란스병원에 내원하여 뇌하수체 기능부전이 의심되어 성장홀몬의 분비능을 관찰하기 위해 L-Dopa 자극시험을 실행했던 35명과 L-Dopa 자극시험과 포도당 부가반응을 관찰하였던 4예의 달단비대증 환자를 연구 검토하여 다음과 같은 결과를 얻었다. 1) 각종 질환에서 성장홀몬의 기저치는 Sheehan씨 증후군에서는 평균치는 대조군보다 낮으나 통계적으로 유의한 차이는 없었고 당뇨병 환자에서도 평균치는 높으나 통계적으로 유의한 차이는 아니었다. 말단비대증 환자 4예 모두 대조군보다 현저한 증가를 보여주었다. 2) 당뇨병 환자 13명종 9명은 당뇨병성 망막증이 합병되었던 환자였고 이중 6명에서 L-Dopa 자극에 성장홀몬의 분비항진을 보여주었다. 망막증이 없었던 4명 중 1명에서만 분비 항진을 보여주었다. 3) Sheehan씨 증후군 10예중 L-Dopa에 분비항진을 보여준 경우는 2예였다. 4) 뇌하수체 혐염기성선종 8예중 L-Dopa 자극반응에 분비항진을 관찰한 수 있었던 것은 1예였다. 5) 4명의 말단비대증 환자중 3명은 호산성 선공이였고 1명은 혐염기성 선종이였다. 이중 3명에서 L-Dopa 자극시험을 행하였는데 1명은 그 측정치가 80 ng/ml 이상이어 반응 판정이 불가능했고 2명은 L-Dopa에 paradoxical response를 보여주었다. 포도당 부가검사를 시행한 2명 모두에서 포도당 투여후 억제반응을 보여주었다. 6) 두개인두종 2예중 1예에서 L-Dopa 자극반응을 보여주었 저신장(short statas)는 2예중 1예에서 L-Dopa 자극후 분비 항진을 보여주었다. This is an analysis of 39 patients studied at the Yonsei Medical Center from January, 1976 to March 1979. Of these 35 patient were suspected of having hypothalamic insufficiency and subjected to the L-Dopa stimulation test to observe growth hormone sceretory function while four acromegaly patient received the glucose loading test and L-Dopa stimulation test. The results are as follows: 1) The basal level of GH in the various disease was as follows: a) The basal level was lower than the control level but was not statisfically significant b) In diabetes the mean value tended to higher than the control level but was not significant statistically c) In all four acromegaly patients the GH level was significantly higher than the control level 2) Of 13 patients with diabetes, nine had diabetic retinopathy, and of those nine, six showed increased L-Dopa response. However, of the four non retinopathic DM patients, onl one showed increased response to L-Dopa. 3) Two patients out of ten with Sheehan's syndrome responded to L-Dopa stimulation. 4) One Patient of eight prith pituitary chromophobe adenoma responded to L-Dopa stimulation. 5) Four acromegaly patients revealed 3 acidophilic adenoma and one chromophobe adenoma histologically. Of patients receiving the L-Dopa stimulation test. Two showed a paradoxical response. Two patients who received the glucose loading test showed supressed response. 6) Of two craniopharyngioma patients, one showed increased GH response after L-Dopa stimulation. Increased response of GH after L-Dopa stimulation was seen in one two craniopharyngioma patients and also in one of two patients with short statasture.

放射線 治療의 迅速正確을 위한 低溫熔融 遮蔽物의 製作과 應用

秋成實,李道行,朴昌潤 대한방사선방어학회 1979 방사선방어학회지 Vol.4 No.1

高에너지 放射線 治療에 있어서 正常組織의 完全遮蔽를 위하여 5∼8cm 납두께의 不定形 遮蔽벽돌을 製作해야 하는 難點이 있었다. 著者들은 납 30.0%, 주석 11.5% 비스므스 48.5%, 카드미늄 10.0%를 四種 共晶結合시켜 密度가 9.8g/㎤이고 熔融溫度가 68℃인 低熔融 遮蔽物質을 開發하여 이를 Lead Y라고 名命하였다. 製作된 Lead Y Block을 68℃에서 熔融시켜 保護해야할 重要한 臟器의 形態대로 製作된 styrofoam 陰刑에 부어서 遮蔽效果가 큰 遮蔽벽돌을 쉽고 安全하게 製作할 수 있었고 납보다 더 단단하고 再現性이 크며 低廉한 가격으로 購入이 可能하므로 放射線 治療效果에 큰 도움을 줄 수 있었다. For accurate and easily shielding irregular shaped organ, its minimized penumbra region and a low melting point alloy "Lead Y" and synchronizing instrument have been developed. The "Lead Y" is the quaternary eutectic alloy and it is composed of Lead 30.0% Tin 11.5% Bismuth 48.5% Cadmium 10.0% The density of its at 22℃ is 9.8g/㎤ and the melting temperature has 40℃ to 68℃. The thickness of "Lead Y" for perfect shielding of Co-60 gamma ray and LINAC 10MeV x-ray is 6cm and 7cm respectively. The "Lead Y" shielding block is casted directly on the styrofoam from which is cut with hot wire of synchronizer device. The special features and advantages of the Lead Y shielding block could be summarized as follows: 1. The shielding block for radiotherapy is rapidly processed only with boiling water and styrofoam. 2. It is not injure one's health and not danger of a fire, because of not generating of any metals vapor and evil smelling. 3. It is very effective to minimize secondary penumbra for the protection of healthy tissue from unnecessary ionizing radiation regardless of the magnification source to skin distance. 4. The HVL of the Lead Y is 1.2cm for Co-60 gamma ray and it's shielding effect if almost same as the pure lead block. 5. The hardness of Lead Y is 1.5 times higher than lead block. 6. It's reavailability is higher than lead block and then one block of Lead Y is reavailable about 30 to 40 times. 7. It is useful for shielding of x-ray, gamma ray, beta-ray, electron and neutron radiation. 8. The materials for Lead Y are easy to acquire with reasonable price and tractable.