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      • KCI등재

        Effect of Cheonggukjang Made with Germinated Soybean on Lipid Contents and Fecal Excretion of Neutral Steroids in Rats Fed a High Cholesterol Diet

        박은석,최수경,Xian-Hua Zhang,최웅규,서정숙 한국식품과학회 2013 Food Science and Biotechnology Vol.22 No.1

        This study was conducted to investigate the effect of cheonggukjang made with soybean germinated under dark and light conditions on lipid content and fecal neutral steroids in rats fed with a high cholesterol diet. Rats were divided into 4 groups: high cholesterol diet (HC);high cholesterol diet containing normal cheonggukjang (HNC); high cholesterol diet containing cheonggukjang made with soybean germinated under dark condition (HDC);high cholesterol diet containing cheonggukjang made with soybean germinated under light condition (HLC). Dietary supplementation with light-reacted cheonggukjang decreased hepatic triglycerides, compared with the other groups. Fecal excretion of total lipids and triglycerides increased when fed with cheonggukjang made with soybean germinated under light condition. Fecal excretion of coprostanol,cholesterol, and coprostanone tended to increase in the cheonggukjang-supplemented groups. These results suggest that dietary supplementation with cheonggukjang made with germinated soybean might prevent hyperlipidemia by improving the lipid metabolism through decreasing the liver triglycerides contents and increasing fecal excretion of triglycerides.

      • KCI등재

        빅데이터 활용을 위한 화재인자 표준화에 관한 연구

        박은석,민세홍 한국방재학회 2019 한국방재학회논문집 Vol.19 No.4

        As a city's population becomes concentrated with economic development, approximately 46,000 fires occur yearly. The fourth industrial revolution necessitated big data analysis of fire-related statistics in the fire fighting sector and fire-related data advancement via fire pattern analysis. For big data analysis of fire statistics, this study analyzed the national fire patterns by reviewing the regional and monthly fire occurrence probability for each fire factor on the fire statistics data provided by the National Fire Agency. The data of the factors possibly causing fire effects were selected by the data evaluation criteria to accordingly assess the fire statistics data quality and build a database. Lastly, they were applied to a fire forecasting platform with standardization by data preprocessing. 경제 발전과 함께 도시의 인구가 밀집하면서 연평균 4만 6천 건에 달하는 화재가 발생하고 있으며, 현재 제 4차 산업혁명에따라 화재소방분야에서도 화재통계 빅데이터 분석 및 화재 패턴 분석을 통한 화재 관련 데이터의 고도화가 필요하게 되었다. 본 연구에서는 화재통계 빅데이터 분석을 위해 소방청에서 제공한 화재통계 데이터에 대한 지역별·월별·화재요인별 화재발생확률을 검토하여 우리나라의 화재패턴을 분석하였다. 이를 통해 화재영향을 줄 수 있는 인자를 데이터 평가 기준을 통해추출하여 화재통계 데이터 품질 평가를 진행하고, 데이터베이스를 구축하였다. 마지막으로, 이러한 데이터를 전처리 과정을통해 표준화하는 작업을 거쳐 이를 화재예측플랫폼에 적용하고자 한다.

      • KCI등재

        타이완 지역 오스트로네시아어 사동문 논항 격 유형

        박은석 영남중국어문학회 2023 중국어문학 Vol.- No.92

        This paper studied the case types of the causative arguments of the Austronesian languages in Taiwan. The languages of the Austronesian family in Taiwan have a unique focus structure that is largely divided into agent focus and non-agent focus(patient focus, locative focus, instrumental focus, peripheral focus). This unique focus structure affects the argument case structure of the causative sentences. This paper investigates the case structure of the two argument causative sentences, three argument causative sentences, and four argument causative sentences of the Austronesian languages in Taiwan, respectively, and classifies the types. It can be seen that the case structure types of the argument differs according to the focus structure types in all of the two argument causative sentences, three argument causative sentences, and four argument causative sentences. In the case of the agent focus two argument causative sentences of the Austronesian languages in Taiwan, the types of argument case can be classified into 4 types. And in all languages, there was a common characteristic that the causer appears as the nominative case. The case structure in which the causer appears as the nominative and the causee appears as the ablative was the most with 8 languages. In the case of the non-agent focus two argument causative sentences of the Austronesian languages in Taiwan, the types of argument case can be classified into 4 types. In the non-agent focus two argument causative sentences, the patient focus sentence and the locative focus sentence were found as the non-agent focus sentence. Languages with non-agent focus, and with the case structure in which the causer appears as the genitive and the causee appears as the nominative were the most with 11 languages. In the case of the agent focus three argument causative sentences of the Austronesian languages in Taiwan, the types of argument case can be classified into 4 types. And in all languages, there was a common characteristic that the causer appears as the nominative case. In the case of the non-agent focus three argument causative sentences of the Austronesian languages in Taiwan, the types of argument case can be classified into 14 types. there was a common characteristic that almost all of the causer appears as the genitive case. Four types of non-agent focus sentence were discovered in the non-agent focus three argument causative sentences, patient focus sentence, locative focus sentence, instrumental focus sentence, and peripheral focus sentence. Languages with non-agent focus, and with the case structure in which the causer appears as the genitive and the causee appears as the nominative and object appears as the ablative were the most with 5 languages. It is difficult to systematically classify the case structure of four argument causative sentences of the Austronesian languages in Taiwan because examples of four argument causative sentences were found only in Puyuma, Sakijaya, and Saroan references. However, considering only the examples found, there was a commonality in that the causer appeared as the genitive case in all three languages. After examining and classifying case types of causative arguments of Austronesian languages in Taiwan, this study compares them with the case types of causative arguments suggested by Dixon (2000:30-83). As a result, it was found that the case types of causative arguments of Austronesian languages in Taiwan and the case types of causative arguments suggested by Dixon only partially matched each other and most of them did not match.

      • SCOPUSKCI등재

        이부프로펜의 가용화

        박은석,지상철,이장원 한국약제학회 1997 Journal of Pharmaceutical Investigation Vol.27 No.4

        In order to formulate 2% ibuprofen solution, the effects of various solublizing agents, such as cosolvents (propylene glycol, polyethylene glycol, glycerin), a complexing agent (CELDEX^ⓡ CH-20), surfactants (Poloxamers and Cremophor^ⓡ RH40) on the solubility of ibuprofen in aqueous solution were evaluated. Among them, Poloxamer 407 and Cremophor^ⓡ RH40 showed the excellent capacity on the solubilization of ibuprofen. After 2% ibuprofen solution of choice were administered orally to rats, in reference to a 2% ibuprofen syrup in the market, the pharmacokinetic parameters were determined. The absorption rate of ibuprofen from the solution was higher than that from the suspension.

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