실내 위치 측위를 통한 D2D 통신 성공 확률 (Opportunity Probability) 측정 및 예측

한규원(Kyuwon Han),남혜린(Hyelin Nam),박지훈(Jihoon Park),성명훈(Meonghoon Seong),김성륜(Seong-Lyun Kim) 한국통신학회 2022 한국통신학회 학술대회논문집 Vol.2022 No.2

본 논문에서는 실내 측위를 진행하고, 그 결과를 바탕으로 D2D 통신 성공 확률인 Opportunity probability (OP)를 예측 및 측정하여 그 값을 비교하는 실험을 소개한다. 실내 측위를 위해서 스마트폰의 관성 측위 센서와 이를 보정하기 위한 딥러닝 네트워크, 그리고 WiFi RTT를 융합한 측위 기법이 사용되었다. 그 결과 OP값을 중위값 90% 이상으로 예측하는 데 성공하였다.

시스템생물학의 한의학적 응용

박영철,이선동,Park, Yeongchul,Lee, Sundong 대한예방한의학회 2016 대한예방한의학회지 Vol.20 No.1

In Korea and China, traditional medicine's holistic approaches, based on the views of whole-body and whole-person, have been applied to make the solution of health problem. However, these holistic approaches of traditional korea or chinese medicine have been limited in interpreting their theories in a view of modern scientific aspects of medicine. This limitation seems to be mainly due to the reductionism approaches of modern scientific medicine. Traditionally, science has taken a reductionism approach; dissecting biological systems into their constituent parts and studying them in isolation. However, systems biology based on omics technologies is providing a new thought and method for traditional medicine's research and interpretation. Systems biology uses integrity study as the characteristic and bioinformatic technology as the key method for connecting reductionism and holism. Therefore, it has much in common with the theory of traditional medicine. It was reviewed that how systems biology is applied to traditional medicine in Korea and China. Also it was suggested that more future researches on interpretation between traditional medicine and systems biology must be focused on personalized medicine since systems biology will have a major impact on future personalized therapeutic approaches.

건축분야 임대형 민자사업 협상단계 쟁점 분석에 관한 연구

박영철,이건,이현철,고성석,Park, Yeong-Cheol,Lee, Gun,Lee, Hyun-Chul,Go, Seong-Seok 한국건설관리학회 2009 한국건설관리학회 논문집 Vol.10 No.5

본 연구는 BTL사업 실시협약을 위한 협상단계에서의 쟁점이 되는 항목의 분석 및 그 발생 원인을 찾아보고 해결방안을 제시하고자 하였다. 이에 기 수행되었거나 또는 수행중인 협상에서 논의되고 쟁점화 되는 항목에 관하여 주무관청과 사업참여자를 대상으로 협상참여 주체들이 인식하고 있는 쟁점화정도를 분석하였다. 또한 협상단계 각 분야별 쟁점항목들의 계층 분석방법을 통한 쌍대비교를 통해 가중치를 산정하고 그 쟁점화정도를 정량적으로 도출하였다. 최종적으로 1차 계층의 6개 협상분야 중 4개 분야에 대한 발생원인 각 2개, 2개 분야에 대한 발생원인 각 1개를 도출한 후 그에 대한 해결방안을 제시하였다. This study aimed to find major issues on negotiations of the BTL project, to analysis the degree, and to investigate the underlying cause and propose solutions. Data were collected from authorities in charge and the companies which have participated in BTL projects. Also, the weights of major issues were analyzed using Analytic Hierarchy Process method(AHP), which uses pair-wise comparison between variables, and the degree of them were listed in the quantitative way. As a result, 4 part had each 2 reasons and others had one reason among 6 negotiation parts of first step. In addition, the solutions were indicated.

엽산 투여에 의한 니코틴-유도 혈장 homocysteine 농도에 대한 영향과 금단증상 완화를 위한 한의학적 처방에 대한 고찰

박영철,신헌태,박해모,이선동,Park, Yeong-Chul,Shin, Heon-Tae,Park, Hae-Mo,Lee, Sun-Dong 대한예방한의학회 2007 대한예방한의학회지 Vol.11 No.1

Homocysteine is a sulfur amino-acid produced during the metabolism of the essential amino acid methionine. Moderately increased plasma total homocysteine concentration have been implicated as a risk factor for occlusive vascular disease. Smoking is known to be one of the most significant factors leading to elevated plasma homocysteine concentration. However, the main component of a cigarette, nicotine has been not studied whether it is linked directly to the increase of homocysteine concentration in blood. The metabolism of homocysteine is closely linked to that of its cofactors, folate. Here, the effects of nicotine and folic acid on amount of plasma homocysteine were studied. The concentration of homocysteine was increased by about 70% in rat plasma after nicotine treatment for one month. This increased concentration of homocysteine was reduced by about 60% at 6 hours later after folate treatment. Thus, nicotine should be directly involved in increasing the concentration of plasma homocysteine. Also it is suggested that these results can be and applied and used for controlling withdrawal symptoms after stopping smoking as one of oriental medicine formulas.

서양의학 독성학의 기본적 개념 및 한약의 $LD_{50}$

박영철,이선동,박경식,Park Yeon-Chul,Lee Sun-Dong,Park Kyoung-Sik 대한예방한의학회 1999 대한예방한의학회지 Vol.3 No.2

Today, toxicology is used for many purpose, in many fields. Classification of special toxic effect is related next 4 important principles. 1. The chemical substance must move to target organ or tissue that can induce Biological effect. For this movement, we have to understand the physical-chemical characteristic of substance, and the rout of absorption, metabolism, diffusion and excretion of toxic substance. 2. Every biological effect that induced by chemical substance is not harmful. For example, some specific chemical substance is not harmful in liver enzyme system. 3. The strength of biological effect induced by chemical substance is deep related with dose. Nearly all substance is not effective below the specific dose, and it may toxic to death over the specific dose. It is the 'Dose - response relationship' But carcinogen may toxic whether it is law dose or not. 4. The information that was obtained by experimental animal test, could have to adapt in human biology. Because biological effect of chemical substance could be different in every biological species. In past, drugs was obtained by animal or plants. But in the future, it could be obtained by biochemistry, and genome project. Therefore, in Oriental medicine, research and approach is needed at this time, and have to develop new method of experience in toxic method.

세라믹/금속접합재의 고온 열사이클에 따른 잔류응력분포 및 굽힘강도 특성

박영철,허선철,부명환,김현수,강재욱,Park, Young-Chul,Hue, Sun-Chul,Boo, Myoung-Hwan,Kim, Hyun-Su,Kang, Jae-Wook 대한기계학회 1997 大韓機械學會論文集A Vol.21 No.10

Since the ceramic/metal joint material is made at a high temperature, the residual stress develops when it is cooled from bonding temperature to room temperature due to remarkable difference of thermal expansion coefficient between ceramic and metal. As residual stress at ceramic/metal joints influences the strength of joints, it is important to estimate residual stress quantitatively. In this study, it is attempted to estimate joint residual stress of Si$_3$N$_4$STS304 joints quantitatively and to compare the strength of joints. The difference of residual stress is measured when repeated thermal cycl is loaded, under the conditions of the practical use of the ceramic/metal joint. The residual stress increases at 1 cycle of thermal load but decreases in 3 cycles to 10 cycles of thermal load. And 4-point bending test is performed to examine the influence of residual stress on fracture strength. As a result, it is known that the stress of joint decreases as the number of thermal cycle increases.

틸트 로터형 무인항공기의 손상허용 설계

박영철,임종빈,박정선,Park, Young Chul,Im, Jong Bin,Park, Jung Sun 항공우주시스템공학회 2007 항공우주시스템공학회지 Vol.1 No.2

The Damage Tolerant Design is developed to help alleviate structural failure and cracking problems in aerospace structures. Recently, the Damage Tolerant Design is required and recommended for most of aircraft design. In this paper, the damage tolerant design is applied to tilt rotor UAV. First of all, the fatigue load spectrum for the tilt rotor UAV is developed and fatigue analysis is performed for the flaperon joint which has FCL (fatigue critical location). Tilt rotor UAV has two modes: helicopter mode when UAV is taking off and landing; fixed wing mode when the tilt rotor UAV is cruising. To make fatigue load spectrum, FELIX is used for helicopter mode. TWIST is used for fixed wing mode. Fatigue analysis of flaperon joint is performed using fatigue load spectrum. E-N curve approach is used for picking crack initiation point. The LEFM(Linear Elastic Fracture Method) is considered for analyzing crack growth or propagation. Finally, including the crack initiation and propagation, the fatigue life is evaluated. Therefore the Damage Tolerant Design can be done.

천궁의 혈액순환과 항산화적 효과

박영철,이선동,허용,김현수,이인선,Park Yeong-Chul,Lee Sun-Dong,Heo Yong,Kim Hyun-Soo,Lee In-Seon 대한예방한의학회 2002 대한예방한의학회지 Vol.6 No.2

Ligusticum Chuanxiong and its components were reviewed in terms of pharmacodynamic mechanisms. Three components of about 40 chemical components in Chuanxiong tetramethylpyrazine, ferulinolol and Butylidenephthalide have mainly been studied for its pharmacodynamic mechanisms which are focused on the increase in blood flow and anti-oxidative stress. The mechanisms for the effects of Chuanxiong on the increase in blood flow can be summarized as four ways, 1) anti-coagulation 2) blocker of ${\beta}1$ adrenergic receptor 3) cellular control of Ca++ level 4) collagen synthesis. Chuanxiong also showed the effectiveness on free radical-induced injury. It seems that its effectiveness is also related to the mechanisms for the increase in blood flow.

독성대사체를 생성하는 다빈도사용 한약재의 안전성등급화 - 천궁, 당귀, 감초, 숙지황을 중심으로 -

박영철,이선동,Park, Yeong-Chul,Lee, Sundong 대한예방한의학회 2015 대한예방한의학회지 Vol.19 No.2

The new formular for herbal medicine-safety classification in terms of evidence-based medicine was developed and applied to evaluate various herbal medicines in the previous study. This study is aimed to evaluate the frequently-used herbal medicines inducing toxic metabolites or reactive intermediates(RI), such as Ligusticum wallichii Franch, Angelica sinensis, Glycyrrhizae Radix, Rehmanniae Radix, based on 6 safety grades calculated from human equivalent dose(HED)-based MOS(margin of safety). HED-based MOS can be explained as the ratio of theoretical ALD(approximate lethal dose) of human as $LD_1$(lethal dose of 1%)/ clinical maximum dose as $ED_{99}$(Effective dose of 99%). The herbal medicine showing the ratio less than 1 belongs to Class 1, but the herbal medicine showing the ratio more than 500 belongs to Class 6 with the lowest toxicity. As a result, they were evaluated as class 2 for Angelica sinensis and Glycyrrhizae Radix, class 3 for Ligusticum wallichii Franch and Rehmanniae Radix. These resultant grades for 4 herbal medicines were lower than the grade expected under consideration that these herbal medicines are used very frequently in oriental clinics. These low grades would be due to their ingredients which is biotransformed to toxic metabolites.

배양망막색소상피세포에서 젤라틴아제의 발현에 대한 산화스트레스의 영향

박영철,최광주,Young-Chul Park,Gwang-Ju Choi 대한안과학회 2005 대한안과학회지 Vol.46 No.11

Purpose: To evaluate the expression pattern of gelatinases in the human retinal pigment epithelial cell line ARPE-19 in response to oxidative stress. Methods: ARPE-19 cells were exposed to paraquat for 72 hours. The cells were assayed for the mRNA expression of gelatinase A and gelatinase B by reverse transcriptase polymerase chain reaction (RT-PCR). The conditioned media were assayed for the production of gelatinases protein by Western blotting. Also, the inhibitory effect of the antioxidants against oxidative stress to the cells was evaluated. Results: The gelatinase levels in the RPE cells increased under oxidative stress compaired with the control (p〈 0.05). Also, the levels decreased when the cells were incubated with the antioxidant N-acetylcysteine (NAC). Conclusions: Oxidative stress upregulates gelatinase expression in ARPE-19 cells.