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자가면역성 용헐성빈혈 환자에서 Parvovirus B19 감염에 의해 발생한 일시적 골수형성부전발증 1예
김준희,김영관,허진국,박두관,이재승 인제대학교 백병원 2003 仁濟醫學 Vol.24 No.1
Human parvovirus Bl9 is a single-strand DNA virus which causes erythema infectiosum, arthralgia, aplastic crisis in patients with red cell defect, iron deficiency anemia, chronic anemia in immunocompromised patients, and fetal hydrops in pregnant women. A 34-year-old man was admitted to our hospital with fever, myalgia and incidental finding of pancytopenia. In peripheral blood, spherocytosis and reticulocytopenia were observed. Bone marrow smear showed many giant pronormoblasts with prominent inclusion bodies and deeply blue cytoplasm. Osmotic fragility of patient's red cells was increased. Human parvovirus B19 DNA was detected by polymerase chain reaction and dot blot hybridization. Pancytopenia was spontaneously resolved with supportive therapy.
정성모 ( Seong Mo Jeong ),강풍 ( Poong Kang ),최효진 ( Hyo Jin Choi ),옥경선 ( Kyung Sun Ok ),박두관 ( Doo Kwan Park ),주미 ( Mee Joo ),한성훈 ( Seong Hoon Han ),이윤우 ( Yun Woo Lee ),이찬희 ( Chan Hee Lee ) 대한류마티스학회 2002 대한류마티스학회지 Vol.9 No.4
Polyarteritis nodosa (PAN) is a disease of small and medium sized muscular arteries, typically involving the skin, kidney, peripheral nerves, muscle and gut. Although its etiology has not been known clearly yet, an immune complex is believed to initiate a vasculitis. Infections, such as hepatitis B virus, hepatitis C virus, and streptococcal infection, may be related with the development of PAN. We experienced a case of PAN preceded by Methicillin resistant staphylococcus aureus-associated otitis media in a 50-year-old woman. This is the first case reported in Korea.