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수치모형을 이용한 DNOC의 물질 거동 모의와 오염원 추정 연구
박경덕,김일규 대한상하수도학회 2017 상하수도학회지 Vol.31 No.1
To estimate pollution sources in the watershed with various industries, the simulation of contamination route and distribution of 2-methyl-4,6-dinitriophenol(DNOC) were performed with a numerical model Hydro Geo Sphere. This study was performed calculations of the load using the measured concentration and simulated flow rate. And, the river was divided by the sampling sites at the mainstream, and the contribution rate at downstream sampling sites was calculated for each section. The results showed the concentration of the downstream sampling sites were decided by the concentration of upstream sites, and the contribution rates of the tributaries were calculated below 10%. The results also showed that the impact of the potential sources in Section 1(Geumho1 ~ Geumho2) and Section 5(Geumho5 ~ Geumho6) was larger than in the other area. In Section1 and Section5, It seemed to require detailed investigation.
한양방통합치료를 병행 후 완치된 재발성 소포림프종 증례 보고
박경덕,김지수,오유나,정범진,정유진,방선휘,Kyung-dug Park,Jisoo Kim,Yoona Oh,Beom-Jin Jeong,Yu-jin Jung,Sunhwi Bang 대한한방내과학회 2023 大韓韓方內科學會誌 Vol.44 No.3
Objective: The purpose of this study is to report the effect of integrative medicine on recurrent follicular lymphoma, thus providing a clinical basis for integrative medicine. Methods: The medical report of a patient with follicular lymphoma who had undergone several chemotherapies but continuously relapsed before treated with integrative medicine was analyzed. Radiologic outcome was assessed by several imaging tests based on Response Evaluation Criteria in Solid Tumors. Clinical outcome and safety were assessed by laboratory tests. Results: After five years of integrative treatment, there was a complete response in imaging tests such as computed tomography (CT), positron-emission tomography/CT, and endoscopy. There were no toxicity in the laboratory test and no serious side effect of integrative medicine. Conclusion: This study suggested that integrative medicine has few side effects but significant effects on treating recurrent follicular lymphoma. However, the results should be taken cautiously as further clinical studies are needed.
박경덕,강동환,조원기,소윤환,김병우,Park, Kyeong-deok,Kang, Dong-hwan,Jo, Won Gi,So, Yoon Hwan,Kim, Byung-Woo 한국환경과학회 2022 한국환경과학회지 Vol.31 No.9
In this study, sediment cores were sampled from tidal flats (six sites) in the west and south coastal wetlands, the blue carbon stock in the tidal flat sediments was calculated, and the blue carbon stock characteristics and influencing factors were analyzed. The sediment particle size of the west coastal tidal flats was larger than that of the south coastal tidal flats, and the organic carbon content in the south coastal tidal flats was more than twice that of the west coastal tidal flats. Blue carbon stock per unit area was 28.4~36.8 Mg/ha on the west coastal tidal flats and 69.8~89.8 Mg/ha on the south coastal tidal flats, which was more than twice higher in the south coastal tidal flats than in the west coastal tidal flats. The total amount of blue carbon stock in the tidal flats was the highest in Suncheon Bay tidal flats at 153,626 Mg, and followed by Gomso Bay tidal flats at 141,750 Mg, Hampyeong Bay tidal flats at 58,420 Mg, Dongdae Bay tidal flats at 44,900 Mg, Cheonsu Bay tidal flats at 36,880 Mg, and Jinhae Bay tidal flats at 26,205 Mg. Blue carbon stock per unit area was higher in the south coastal tidal flats, but the total amount of blue carbon stock in the tidal flats was higher in the west coast. The slope of the regression function of blue carbon stock with respect to the organic carbon content in the tidal flat sediments was estimated to be about 0.05 to 0.07, and the slope of the regression function was higher in the west coastal tidal flats than in the south coastal tidal flats.
Ferrate(VI)를 이용한 다양한 수중 환경에서의 tetracycline의 분해 특성 및 반응 경로 연구
박경덕,김일규 대한상하수도학회 2021 상하수도학회지 Vol.35 No.1
Tetracycline is one of the most commonly used as antibiotics for the livestock industry and it is still widely used nowadays. Tetracycline and its metabolites are excreted with excrement, which is difficult to completely removed with conventional sewage treatment, therefore it is apprehended that the tetracycline-resistant bacteria occurs. In this study, the oxidant named ferrate(VI) was used to degrade the tetracycline and investigate the reaction between ferrate(VI) and tetracycline under various aqueous conditions. The highest degradation efficiency of tetracycline occurred in basic condition (pH 10.1 ± 0.1) because of the pKa values of tetracycline and ferrate(VI). The results also showed the effect of water temperature on the degradation of tetracycline was not significant. In addition, the dosage of ferrate(VI) was higher, the degradation of tetracycline and the self-degradation of ferrate(VI) also higher, finally the efficiency of ferrate(VI) was lower. The results said that the various mechanisms effects the reaction of ferrate(VI) oxidation, it required the consideration of the characteristics of the target compound for optimal degradation efficiency. Additionally, intermediate products were detected with LC/MS/MS and three degradation pathways were proposed.
Diagnosis and Treatment of Cutaneous Aspergillosis
박경덕 대한의진균학회 2021 대한의진균학회지 Vol.26 No.4
Aspergillosis is an opportunistic mycosis caused by fungi in the genus Aspergillus, mostly A. fumigatus and A. flavus. Typical entry portals in primary cutaneous aspergillosis include burns, trauma sites, surgical wounds, intravenous catheters, and macerated skin in underlying occlusive dressings. In individuals who are immunocompromised, the dissemination risk is significant. Skin findings range from firm papules and necrotic papulonodules to hemorrhagic bullae and ulcers. The prognosis is poor but improves when the patient is no longer neutropenic or when corticosteroids are discontinued. Localized primary cutaneous aspergillosis can be excised surgically, followed by oral antifungal administration. For the first-line treatment of pulmonary invasive aspergillosis, isavuconazole and voriconazole are the preferred agents, whereas liposomal amphotericin B is supported moderately.
박경덕,강동환,조원기,양민준,Park, Kyoung-deok,Kang, Dong-hwan,Jo, Won Gi,Yang, Minjune 한국환경과학회 2022 한국환경과학회지 Vol.31 No.5
This study analyzed the temporal and spatial characteristics of water quality for five hydropower dam reservoirs in South Korea. Water temperature, pH, dissolved oxygen, and chlorophyll-a (Chl-a) showed high fluctuations in summer and autumn at all reservoirs, indicating the existence of seasonal effects. At all five reservoirs, the concentrations of suspended solids (SS) and total nitrogen (TN) fell under the "slightly bad" category and those of total organic carbon (TOC) fell under the "slightly good" category or higher, according to "the standard for living environment of lake water quality." Variations in the concentration ranges and degrees of change in SS, TN, and TOC among reservoirs were observed, indicating the influences of rainfall, surrounding environments, and seasonal changes. Daecheong and Namgang Dam showed high Chl-a concentrations in summer, indicating that the metabolism of microbial communities, such as algae, was active.