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      • SCOPUSKCI등재

        신장 허혈이 토끼 신피질 절편에서 아미노산 이동에 미치는 영향

        남윤정,김주헌,Nam, Yun-jeong,Kim, Joo-heon 대한수의학회 1997 大韓獸醫學會誌 Vol.37 No.1

        This study was carried out determine the effect of renal ischemia on amino acid transport in rabbit renal cortical slices. The animal models of renal ischemia induced experimentally by clamping the renal artery. These results were summarized as follows: 1. The uptake of amino acids lysine and ${\alpha}$-aminobutyrate(AIB), dicarboxylate succinate and organic anion PAH in cortical slices was normal or increased after 30 or 60 min of ischemia in vivo. 2. In a 30 min ischemic kidney, the slice uptake of amino acids was returned to the control level by 30 min of reflow. In a 60 or 90 min ischemic kidney, the lysine uptake was returned to the control level after of reflow, but the uptake of AIB and succinate was significantly reduced during reflow period of 30-120 min. 3. Oxygen consumption in cortical slices was increased after 30 min of ischemia but was not altered by 60 min of ischemia. This results indicat that transient ischemia caused increasing of amino acid uptake in renal cortical slices without metabolic disorder of renal proximal tubule.

      • SCOPUSKCI등재

        신장 허혈이 토끼 신기능과 lysine 및 alanine 배설에 미치는 영향

        남윤정,김용근,김주헌,Nam, Yun-jeong,Kim, Yong-keun,Kim, Joo-heon 대한수의학회 1995 大韓獸醫學會誌 Vol.35 No.4

        This study was carried out to determine the effect of renal ischemia on renal function and excretion of amino acid in rabbit. The animal models of renal ischemia induced experimentally by clamping the renal artery for different lengths of time. These results were summarized as follows: 1. Ischemia for 30 or 60 min produced a polyuria which is accompanied by an increase in $Na^+$ excretion. Glomerular filtration rate (GFR) and p-aminohippurate plasma($C_{PAH}$) were not altered by 30 min of ischemia, indicating that transient ischemia results in a marked tubular dysfuction before a reduction in GFR or renal blood flow. 2. Reabsorption of glucose and amino acids such as alanine and lysine was markedly reduced after 30 min of ischemia, and the effect was more pronounced after 60 min of ischemia.

      • SCOPUSKCI등재

        돼지 적출 신동맥에 대한 adenosine triphosphate의 영향과 Ca<sup>++</sup>의 동원

        남윤정,김주헌,Nam, Yun-jeong,Kim, Joo-heon 대한수의학회 1991 大韓獸醫學會誌 Vol.31 No.3

        The aims of this study were to investigate the effect of adenosine triphosphate (ATP), which has been known as the neurotransmitter of nonadrenergic, noncholinergic nerves, and the source of $Ca^{\sharp}$ in the effect of ATP on the isolated renal artery of pig. The results of this study were summarized as follows: 1. ATP caused the contraction and the contractile responses were increased in a dose-dependent manner between the concentration of ATP $2{\times}10^{-3}M$ and $10^{-2}M$ on the isolated renal artery of pig. 2. The contractile responses induced by ATP $(5{\times}10^{-3}M)$ were not blocked by pretreatment with cholinergic receptor blocker (atropine, $10^{-6}M$), $\alpha$-adrenergic recptor blocker(phentolamine, $10^{-6}M$) or $\beta$-adrenergic receptor blocker (propranolol, $10^{-6}M$), and $H_1$-receptor blocker (pyrilamine, $10^{-6}M$) or $H_2$-receptor blocker (cimetidine, $10^{-6}M$) on the isolated renal artery of pig. 3. The contractile responses induced by ATP $(5{\times}10^{-3}M)$ were not appeared in $Ca^{\sharp}$-free medium. As the concentration of $Ca^{\sharp}$ in $Ca^{\sharp}$-free medium was increased, the contractile responses induced by ATP $(5{\times}10^{-3}M)$ were enhanced but were completely inhibited by pretreatment with $Ca^{\sharp}$-channel blocker, papaverine $(5{\times}10^{-5}M)$ or verapamil $(5{\times}10^{-5}M)$ on the isolated renal artery of pig.

      • KCI등재

        청소년 독자개발을 위한 지역사회 아웃리치 서비스 연구 - 서비스 디자인 방법론을 활용하여 -

        남윤정 ( Nam Yun Jeong ),정영국 ( Jeong Young Kuk ),이정연 ( Lee Joung Youn ) 디자인융복합학회 2017 디자인융복합연구 Vol.16 No.4

        본 연구는 청소년 독자개발을 위한 지역사회 아웃리치 서비스의 가능성을 탐색하였다. 청소년기는 아동기에 비해 독서량이 현저히 하락한다. 입시교육과 형식적인 독서교육으로 인해 독서시간과 흥미가 줄어들기 때문이다. 이 연구는 사용자 경험에서 출발하는 서비스디자인 관점으로 청소년들이 책을 쉽게 접하고 재미있게 독서습관을 쌓을 수 있는 독서서비스 방안을 다음과 같이 모색하였다. 첫째, 청소년의 주요 활동영역인 사적공간에 새로운 도서관 아웃리치 서비스가 가능하다. 둘째, 사적공간을 통한 아웃리치 서비스는 청소년들의 관심에 맞는 북큐레이션과 자발적 도서 선택이 이루어져야한다. 셋째, 서비스 프로세스는 청소년들의 필수품인 스마트폰 애플리케이션을 플랫폼으로 구성하는 것이 적절하다. 이 결과를 바탕으로 청소년 독자 개발을 위한 지역사회 아웃리치 서비스 `Bookrunner`의 서비스 시나리오를 수립하였고 청소년을 중심으로 한 새로운 독서생태계로의 변화를 제안한다. This study explored the possibility of new community outreach services for youth reader development. In adolescence, the amount of reading is significant lower than in childhood, for the emphasis on university entrance exam reduces the time available for reading and the perfunctory reading education fails to raise interest in reading. This study seeks to solve the problem from a service design perspective focusing on the experiences of young readers. In particular, it aims to offer them easy access to books and help them build enjoyable reading habit. First, it found a new possibility for library outreach service in `private space` which is the central activity area for the youth. Second, it is essential to offer a curation service specifically designed for them and still offer room for selection according to their interests. Third, the service process can be effectively structured when a smartphone application is used as a platform. Based on these findings, we developed a service scenario of `Bookrunner`, a community outreach service for the development of young readers, and propose a new reading ecosystem centered on youth.

      • KCI등재

        STEAM 교육을 위한 로봇 콘텐츠 개발

        남윤정(Yun Jeong Nam),김희선(Hee Sun Kim) 한국산업정보학회 2015 한국산업정보학회논문지 Vol.20 No.1

        로봇을 이용한 교육은 학생들에게 고차원의 사고, 창의적 표현, 발견 학습의 기회를 제공하고 있다. 또한 로봇을 통해 다양한 교과 영역을 가르칠 수 있으므로 STEAM 교육에도 적합한 도구라 볼 수 있다. 따라서 본 연구에서는 로봇을 이용한 STEAM 교육 콘텐츠를 설계하고 개발하였다. 초등학교 교과서를 분석하여 과학, 기술, 공학, 예술, 수학에서 로봇을 통해 효과적으로 전달 가능한 내용들을 추출하여 융합 콘텐츠를 설계하였다. 설계한 내용을 바탕으로 로봇을 조립하고, 프로그램하여 콘텐츠를 개발하였다. 개발된 콘텐츠를 초등학교 방과 후 수업에 직접 적용하였고, 수업 후 설문조사를 통해 교과목의 이해도와 흥미도, 참여도를 평가하였다. 연구결과 로봇을 활용한 STEAM 콘텐츠 수업에서 교과내용의 이해도와 흥미도, 참여도가 높게 나타났다. 이를 통해 STEAM 교육에 로봇의 활용이 교육적 효과가 있다는 점과 개별 교과지식보다 STEAM기반의 융합형 콘텐츠를 이용한 교육의 효과가 높다는 점을 확인할 수 있었다. Educational learning methods that take advantage of a robot provide opportunities for students to develop high dimensional thinking, a creative expression and discovery learning opportunity. It is also perceived as a suitable tool for STEAM systems which can be used in a variety of school curriculums. Therefore we designed and developed STEAM educational contents using robots in this study. This study analyze elementary text books and design the convergence contents from various subjects such as math, science, engineering and art through a robot. This study has developed educational materials by making a robot based on the designed contents. They have been applied to after school materials and then evaluated for comprehension, interest and participation. The results of this study have shown very encouraging evaluations from participating students. Accordingly, this study has shown that STEAM contents that take advantage of a robot have improved student participation, interests, and comprehension in the curriculums. Additionally, integrating STEAM educational content has proved more effective in contrast to being separated

      • SCOPUSKCI등재

        개 적출 신동맥에 있어서 histamine receptor의 생리적 특성

        김주헌,남윤정,Kim, Joo-heon,Nam, Yun-jeong 대한수의학회 1989 大韓獸醫學會誌 Vol.29 No.2

        To elucidate the physiological characteristics of histamine receptor of the isolated renal artery in dog, effects of various receptor blockers and $Ca^{{+}{+}}$ channel blockers on the contractile responses of histamine were investigated in the isolated renal artery of dog. The results were summarized as follows: 1. Histamine caused the contraction in the isolated renal artery of dog, and the contractile responses increased between the concentration of $5{\times}10^{-6}M$ and $10^{-2}M$ in dose-dependent manner. 2. The contractile response induced by histamine ($10^{-3}M$) was not blocked by pretreatment with atropine ($10^{-6}M$), phentolamine ($10^{-6}M$), propranolol ($10^{-6}M$) or cimetidine ($10^{-6}M$), but was completely blocked by pretreatment with pyrilamine ($10^{-6}M$). 3. The contractility induced by histamine ($10^{-3}M$) was decreased in the $Ca^{{+}{+}}$ free medium. 4. The contractile response induced by histamine ($10^{-3}M$) was markedly inhibited by pretreatment with papaverine ($5{\times}10^{-5}M$) or verapamil ($5{\times}10^{-5}M$). 5. After the pre-contraction induced by norepinephrine ($10^{-7}M$) or prostaglandin $F2{\alpha}$ ($5{\times}10^{-6}M$), the contractile response induced by the additional treatment of histamine ($10^{-3}M$) was markedly increased compared with that of histamine ($10^{-3}M$) alone.

      • 난포기 및 황체기에 있어서 돼지 난관 협부 평활근의 neurotransmitter들의 수축효과에 대한 estradiol-17β및 progesterone의 영향

        이민기,노규진,심철수,남윤정,김주현,최상용 慶尙大學校 1991 論文集 Vol.30 No.2

        The effects of estradiol-17β or progesterone on the contractility of neurotransmitters on pig oviductal isthmic smooth muscle were investigated. The motility of the isolated smooth muscle was recorded by using physiological recording system. The results were summarized as follows : 1. The contractility induced by histamine or prostaglandin F2α was depressed by the pretreatment of estradiol-17β but was not by the preteatment of progesterone in follicular or luteal stage. 2. The contractility induced by acetylcholine was depressed un follicular stage but excited in luteal stage by the pretreatment of estradiol-17β or progesterone. 3. The contractility induced by norepinephrine was depressed by the pretreatment of progesterone in follicular stage but was excited by the pretreatment estradiol-17β in luteal stage.

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