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관을 흐르는 균일입자 - 모래 - 물 슬러리의 최소수송속도
김홍태,이철수,한균석,박찬교 한국화학공학회 1984 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.22 No.3
비구형 입자인 모래와 물의 슬러리계에서 최소 수송 속도를 구하기 위해 입자의 크기를 측정치 않는 침강 속도의 함수로 관련식을 제시하였다. 고체 농도가 약 1-20% 범위의 실험에서 농도가 15%까지는 농도에 따라 최소 수송 속도가 증가한 반면, 그 이상의 농도에서는 고체 입자의 농도에 무관하였다. The minimum transport velocity of sand-water slurry system in the concentration range of 1-20 volume % has been correlated in terms of particle settling velocity. Minimum transport velocity of slurries increased with the concentration of sand until the value reaches 15%. Thereafter, the minimum transport velocity is independent of slurry concentration.
김홍태,최재덕,김병규,강호철,이종수 대한암학회 2016 Cancer Research and Treatment Vol.48 No.1
Purpose Heterochromatin protein 1γ (HP1γ ) interacts with chromosomes by binding to lysine 9-methylated histone H3 or DNA/RNA. HP1γ is involved in various biological processes. The purpose of this study is to gain an understanding of how HP1γ functions in these processes by identifying HP1γ -binding proteins using mass spectrometry. Materials and Methods We performed affinity purification of HP1γ -binding proteins using G1/S phase or prometaphase HEK293T cell lysates that transiently express mock or FLAG-HP1γ . Coomassie staining was performed for HP1γ -binding complexes, using cell lysates prepared by affinity chromatography FLAG-agarose beads, and the bands were digested and then analyzed using a mass spectrometry. Results We identified 99 HP1γ -binding proteins with diverse cellular functions, including spliceo- some, regulation of the actin cytoskeleton, tight junction, pathogenic Escherichia coli infec- tion, mammalian target of rapamycin signaling pathway, nucleotide excision repair, DNA replication, homologous recombination, and mismatch repair. Conclusion Our results suggested that HP1γ is functionally active in DNA damage response via protein- protein interaction.
김홍태,이문식,강순부,Kim, HongTae,Lee, MoonSik,Kang, Sunbu 한국융합보안학회 2014 융합보안 논문지 Vol.14 No.6
군사분야에는 개인의 신상정보 수준에서부터 국가의 존망에 영향을 미치는 수준의 정보까지 다양한 정보들이 존재한다. 암호 알고리즘은 이러한 정보들을 안전하게 관리하는데 해결책을 제시해 줄 수 있다. 우리는 온라인 상에서 비밀스럽게 처리되어야 하는 군사분야 자료를 효과적으로 관리할 수 있는 검색 가능 암호 알고리즘을 제안한다. 추가적으로, 상황에 따라 군사분야 자료 관리에 효과적인 알고리즘을 모색한다. There exists vast amount of information in the military, both at the personal level and at the national security level. Cryptographic algorithms can present a solution to managing this information safely. We suggest searchable encryption algorithms for efficiently managing military data, which should be treated securely in an online environment. Furthermore, we investigate algorithms that are effective for managing military data under various conditions.
해사안전을 위한 IMO의 인적요인 관련 정책 및 주요 이슈
김홍태,이성엽,이다희,이종갑 한국항해항만학회 2022 한국항해항만학회 학술대회논문집 Vol.2022 No.2
IMO는 “인적 요인은 해양안전, 보안, 그리고 해양환경보호에 영향을 주는 복합적이고 다차원적인 문제이며, 선박의 승무원, 육상의관리자, 감독기관, 선급, 조선소, 입법기관 등에 의해 수행되는 모든 인간 활동을 포함한다. 효과적으로 인적요인에 대한 문제를 다루기 위해서는 이러한 모든 이해 당사자들이 협조해야 되는 문제” 라고 정의하고 있다. 본 발표에서는 인적 요인 관련 의제의 배경 및 논의경과, 최근 기술이슈, 기술동향 및 전망, KRISO의 대응방안을 소개하고자 한다. 향후 관련 IMO 의제 대응, 연구개발 방향설정, 국내 해양환경 정책 수립 등에활용될 수 있다.
김홍태,유병세,임재민 한국경영과학회 1998 한국경영과학회 학술대회논문집 Vol.- No.1
본 논문은 조선공정 중 선각공정에 대한 공정관리 시스템의 개발에 대한 내용을 나타내고 있다. 조선에서의 선각공정은 전 처리된 강판을 설계도면대로 마킹, 절단, 곡가공을 거쳐 부재를 만드는 가공공정, 여러 가지 모양으로 가공된 부재들을 용접하여 일정한 모양의 블록으로 만들어 가는 조립공정, 조립된 블록들을 선대 혹은 도크 내에서 용접작업을 통하여 하나씩 쌓아 올려 선박의 형체를 만드는 탑재공정으로 구분된다. 본 논문에서는 선각공정을 이루고 있는 가공, 조립, 탑재공정에 대해 공정흐름의 역방향인 탑재, 조립, 가공공정의 순서로 각 공정에 대한 공정계획 및 일정계획 시스템을 개발하였다.
고지방 사료 급여 마우스에서 인진쑥 추출물의 항비만 효과
김홍태,김대동,구세광,김주완,장광호,오태호,이근우 한국임상수의학회 2010 한국임상수의학회지 Vol.27 No.4
Artemisia capillaries THUNB is a perennial herb that belongs to the family compositae spp. and the most common plant among the various herbal folk remedies used in treatment of abdominal pain, hepatitis, chronic liver disease, jaundice and coughing in Korea. The object of this study is to observe the dosage-dependent anti-obestic effects of an aqueous extracts of dried aqueous extracts of stems of Artemisia capillaris Thunberg. [Artemisiae capillaris Herba, In-Jin in Korean, INJ] on 45%/Kcal high fat diet (HFD) supplied mice. 45%/Kcal rodent HFD are supplied to ICR mice from 1 week before initiation of INJ administration throughout the 12 weeks, and after the end of 12weeks of 62.5, 125 and 250 mg/kg/day of INJ administration, the efficacy was divided into five categories 1)hypoglycemic, 2) hepato-protective, 3) nephroprotective, 4) hypolipemic, and 5) anti- obesity effects. The effects were compared to those of simvastatin (for hypolipemic activity), silymarin (for hepatoprotective and free radical scavenger effects) and metformin (for hypoglycemic and related anti-obesity effects). 7 animals per group (8 groups; total 56adapted mice on HFD were selected base on the body weight at 6 days after initiation of HFD supply) were used in this experiment. INJ and all three different reference drugs were directly suspended or dissolved in distilled water,and administered at a volume of 10 mL/kg, once a day for 84 days from 1 week after HFD supply. As results of 91 days of continuous HFD supply, mice showed marked obese states, hyperglycemia, hyperlipemia, liver damages and kidney damages. These mean the obesity, diabetes, diabetic hepatopathies, nephropathies and hyperlipemia were induced by HFD supply. After end of 84 days of continuous treatment of three different dosages of INJ, all diabetes related complications were inhibited; relatively favorable anti-obesity, hypolipemic, hepatoprotective, hypoglycemic and nephroprotective effects. These favorable effects showed relatively good dose-relations between all three different dosages of INJ treated, and INJ 250 mg/kg showed enough favorable effects on diabetes and related four complications tested as compared with one of each three different references. Otherwise, the efficacy of 62.5 and 125 mg/kg of INJ was somewhat slighter than those of all three reference drugs. Therefore, the suitable effective dosage of INJ is considered as 250 mg/kg/day in the present study. The overall anti-obesity effects of INJ 250 mg/kg-treated group was similar or more favorable than those of metformin 250 mg/kg-treated group, and INJ 250 mg/kg showed slighter hypoglycemic effects with silymarin 100 mg/kg and metformin 250 mg/kg, similar hypolipemic effects with simvastatin 10 mg/kg, and similar hepatoprotective effects with silymarin 100 mg/kg, and similar nephroprotective effects with that of silymarin 100 mg/kg and metformin 250 mg/kg, respectively. Obese, hyperglycemia, hyperlipemia, steatohepatitis and related nephropathies induced by HFD supply were dramatically inhibited by 84 days of continuous treatment of all three different dosages of INJ. It is, therefore expected that INJ extracts will be a favorable alternative agent for diet-related diabetes and complications.