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김홍배,강경화,황원덕,유선애,이승연,Kim, Hong-Bae,Kang, Kyung-Hwa,Hwang, Won-Deuk,Lyu, Sun-Ae,Lee, Seung-Yeon 대한한방소아과학회 2009 대한한방소아과학회지 Vol.23 No.3
Objectives To evaluate that Okwada affected which factors for treatment of lung fibrosis. Methods Bleomycin induced lung fibrosis model made in mice. After Okwada lyophilized, power sample obtained and melt in distilled water. Okwada solution administered mice through oral route on 21 days after bleomycin instillation and this procedure performed once a day for 7 days. We divided by three groups; normal (control), bleomycin induced lung fibrosis without treatment (experimental), bleomycin induced lung fibrosis with treatment (treatment). On six weeks after bleomycin instillation, mice sacrificed and removed lung. We performed Western blot analysis for TGF-beta, phosphodiesterase 5A, interleukin (4,5,13) and compared therapeutic effects of Okwada. Results On western blot analysis, all normal and experimental mice detected TGF-beta, phosphodiesterase 5A, interleukin 4,5,13. The amount of band of TGF-beta, phosphodiesterase 5A, interleukin 5 in experimental and treatment group was similar. However, interleukin 4,13 of treatment group decreased compared with experimental group. Conclusions Okwada would be effected the lung fibrosis through suppression of interleukin 4,13.
升麻葛根湯의 항히스타민 효과 및 IL-4와 GM-CSF 발현에 미치는 영향
김홍배,김원일,이승연,Kim, Hong-Bae,Kim, Own-Il,Lee, Seung-Yeon 대한한방소아과학회 2006 대한한방소아과학회지 Vol.20 No.1
We investigated the effect of Sungmagalkun-tang (SGT) on the allergy. We conformed compound 48/80-induced active systemic anaphylatic shock, anti-dinitrophenyl IgE-mediated passive cutaneous anaphylaxis and ovalbumin-induced anaphylatic shock. Also observed IL-4 and GM-CSF mRNA expression in ovalbumin-induced allergic lung tissue and RBL-2H3. Histamine release is measured in RBL-2H3. SGT inhibited active systemic anaphylatic shock, passive cutaneous anaphylaxis and ovalbumin-induced anaphylatic shock by oral administration. We observed that SGT was concentration-dependently reduced IL-4 and GM-CSF mRNA expression in ovalbumin-induced allergic lung tissue and RBL-2H3 by SGT. In addition, SGT reduced histamine release in RBL-2H3. These results indicate that SGT has anti-histamic effect and controls IL-4 and GM-CSF mRNA expression on allergy.
로버트 벤츄리의 건축에 표현된 양자공존적(兩者共存的) 대입(對立)에 관한 연구 - Mother's House을 중심으로 -
김홍배,이남규,Kim, Hong-Bae,Lee, Nam-Gyu 한국주거학회 2011 한국주거학회 논문집 Vol.22 No.4
This study was conducted to investigate the ambivalent characteristics of dichotomous contradictions expressed by Robert Venturi's architecture. It focused on his Mother's House, which applied his theoretical practices faithfully among many of his architectural works. First, he sought to change interior and exterior spaces by manipulating the architectural scales of "Mother's House". He achieved tension in space through structural complexities in combination with contradictions. Second, as for the characteristics of ambivalent contradictions, including linear and geometric forms, and plane, there were familarity which emphasizes tradition; external appearances of symmetry and asymmetry which give a comfort feeling; openness and closedness, which were expressed with the size of windows and objects such as molding. Third, the fireplace-chimney and the stair were forming appropriate harmony between contradiction and complexity as they competed for central position on the plane.
Fabrication of InSb TFT and Parameters EXtraction Using Optimization Technique
김홍배,손상희,곽계달,Kim, Hong Bae,Son, Sang Hee,Kwack, Kae Dal The Institute of Electronics and Information Engin 1987 전자공학회논문지 Vol.24 No.1
InSb TFT is fabricated by the vacuum evaporation method and I-V characteristics are measured. Employing Davidon Fletcher-Powell algorithm, the device parameters are extracted. The current-voltage relations calculated by extracdted parameters are in good agreement with experimental results. It is found that optimization technique may be more simple and accurate than curve fitting method in device parameters extration.
비전 이미지 프로세싱을 이용한 외관검사가 가능한 기계시스템 및 비전 알고리즘 개발
김영춘(Kim, Young-Choon),김영만(Kim, Young-Man),김성길(Kim, Sung-Gil),김홍배(Kim, Hong-Bae),조문택(Cho, Moon-Taek) 한국산학기술학회 2016 한국산학기술학회논문지 Vol.17 No.2
본 논문에서는 저가의 카메라를 활용하여 육안 검사로 해왔던 c-tray와 관련된 불량을 비전 이미지 기술을 활용하여 자동으로 검사하였으며, 4대 검사항목인 트레이내 디바이스 겹침, 트레이 휨, 트레이 적재수량, 트레이내 디바이스 포켓 이탈 등 불량유형을 define 및 검출하는 알고리즘을 개발하였다. 따라서, 개발한 헨들링 시스템으로 인해 c-tray의 스택이나 기타 포장 공정에서의 수량 확인 공정 등에 확대 적용이 가능하였다. 그리고 제어를 활용한 비전 이미지를 처리하고 사용자 gui를 처리하는 제어프로그램과 스캔 속도에 맞춰 최적의 검사 이미지를 확보할 수 있는 기계 작동제어 프로그램을 개발하여 비전 데이터 처리와 이미지 획득이 가능한 기계 시스템을 설계하였다. In this study, the defect in connection with a C-tray was inspected using a low-cost camera. The four test items were the device overlapping in the tray, the bending of the tray, the loaded quantity of the tray, and the device pocket leaving, an algorithm was developed for defining and detecting the above defect types. Therefore, the developed handling system could extend the application of the stack of the c-tray and provide a quantity verification inspection on the packing processing. The machine operation control program, which can ensure the optimal inspection image to match the scan speed, was developed and the control program that can process the user gui and the vision image utilizing the control was developed. Overall, a mechanical system that is practicable for obtaining an image and processing the vision data was designed.
Isolating Vibration of a Miniature Linear Cryogenic Cooler with a Tuned Vibration Absorber
Young-Keun Kim(김영근),Hong-Bae Kim(김홍배),Eunghyun Kim(김응현),Kyung-Soo Kim(김경수) 대한기계학회 2009 대한기계학회 춘추학술대회 Vol.2009 No.11
Modern surveillance equipments rely on infrared(IR) sensors for detection and observation purposes. The IR sensor is connected to a miniature cryogenic cooler to maintain at the temperature as low as 77K. However, the image quality of the sensor is degraded by the transmission of vibration disturbances from the cooler. Therefore, to maintain the high image quality of the image, the compressor vibration and the force transmitted to the sensor have to be mitigated. For the compressor isolation system, this paper proposes a tuned dynamic vibration absorber with the combination of a passive isolator. A cryogenic compressor bracket and springs are designed to allow the absorber mass to mitigate the vibration jitter in the axial direction. The system design is analyzed and tested for dynamic suppression of the harmonic force at the operating frequency of the cooler.