http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
사람 뇨의 γ - Glutamyl Transpeptidase
김호중,이민화 ( Ho Jung Kim,Min Wha Lee ) 생화학분자생물학회 1976 BMB Reports Vol.9 No.3
A crude urinary protein concentrate was prepared by treating human urine with amrnonium sulfate, and was found to be active in hydrolyzing the synthetic substrate, r-glutamyl-p-nitroanilide. The hydrolytic activity of the urine enzyme was most efficient at pH 8.5 in tris buffer in the presence of glycylglycine as a r-glutamyl acceptor. L-Glutamine and L-methionine also acted as a r-glutamyl acceptor, but L-glutamic acid, L-arginine, glycine, L-valine, L-aspartic acid, and L-homoserine inhibited the enzyme, suggesting that these amino acids do not act as r-glutamyl acceptors. The enzyme was markedly inhibited by bromosulfophthalein, oxidized glutathione, and by L-serine in the presence of borate, the inhibition being more marked than is the cage with human serum and rat kidney enzymes. L mike rat kidney enzymes, the urine enzyme did not show phosphate-independent and maleate-stimulated glutaminase activity. The urinary enzyme activity was not correlated with the serum enzyme activity in various disease entities such as liver disease, kidney and urinary tract infections, and others.
혈액투석 환자에 있어 투석 간격시간 및 투석중 칼륨 제거량이 혈중 칼륨 농도에 미치는 영향
김호중(Ho Jung Kim),노광호(Kwang Ho Roh),이경원(Kyung Won Lee),김진영(Jin Yeong Kim),유준호(Joon Ho Ryu),문중돈(Joong Don Moon),박일규(Il Gyu Park) 대한신장학회 2000 Kidney Research and Clinical Practice Vol.19 No.1
N/A To evaluate potassium(K) homeostasis during in-terdialytic and dialytic phases in chronic hemodialysis patients, we analyzed pre- and post- dialysis plasma K concentration(n=28) over n week with an interdialytic interval of 7Zhrs, 48hrs(l), and 48hrs(II), respectively, and the quantity of total dialytic K removal via dialysate. The predialysis plasma K at 72h interval(prePK72h: 4.89±0.17mEq/L) was significantly higher than those at 48h interval(prePK48h-I: 4.57±0.15mEq/L, and prePK48h-II: 4.40±15mEq/L) (p=0.000, p=0.000). 10.7% in prePK72h were categorized into severe hyperkalemia more than 6.0mEq/L, but none in prePK48h-I, II(p=0.000, p=0.000). In contrast no difference between 72-h and 42-h intervals was found in the postdialysis plasma K(postPK72h: 3.59±0.07 vs postPK48h-I : 3.530±08mEq/L, p>0.05) and in the quantity of total dialytic K removal via dialysate(ΔKtota172h : 74±2.6 vs ΔKtota148h-I:71±2.2mEq, p>0.05). On approach to this with two-compartment model, there was significant difference in dialytic K removal from ECF(ΔKecf72h:22.2±1.6 vs ΔKecf48h-I:17.7±1.6mEq, p<0.01), but not in that from ICF(ΔKicf72h:51.6±3.1 vs ΔKicf48h-I: 53.5±2.7mEq, p>0.05). In all 28 patients, age, sex and body weight were not correlated with either pre- and post- plasma K levels or total K removal per kg body weight. In conclusion, the majority of dialytic K removal is from the replenishment of the ICF potassium and it has rather constant feature in that there was no autoregulatory increment even with the higher predialysis plasma K concentration. So the plasma K concentration on chronic maintenace hemodialysis is more dependent on the potassium gain during interdialytic phase than the potassium removal during dialytic phase. Also it is reasonable to restrict dietary K intake and apply K-exalate orientating to the interdialytic phase of 72hrs because severe hyperkalemia is rare in that of 48hrs.
비감사서비스와 감사보수로 측정한 감사인의 독립성과의 관련성
김호중(Ho jung Kim),우정현(Jung hyun Woo),김미옥(Mi oak Kim) 건국대학교 경제경영연구소 2004 商經硏究 Vol.29 No.2
The question of whether an auditor should be permitted to provide non-audit services to an audit client has been recently debated. It has been argued that providing both audit and non-audit services to the same clients may create a conflict of interests, particularly when an auditor may treat the audit service as a “loss leader” to trigger non-audit service contracts that generally produce high revenues to the auditor. The auditor supplying both audit and non-audit services to the same clients would hesitate to issue honest audit opinions for fear that he/she would lose his/her lucrative business, non-audit services. If that’s the case, providing both services to the same clients should be a serious threat to the nexus of audit services-auditor independence. In this study, we examine the effect on audit fees of providing both audit and non-audit service to the same clients. If auditors tend to use the audit service as a “loss leader” to attract lucrative non-audit services from the same clients, audit fees would be sharply cut down, and thus the audit quality wold be deteriorated. In this sense, the audit fee may proxy the auditor independence. The empirical results show that audit fees for clients who purchase non-audit services from their auditors are higher than those for clients who do not do so. They imply that, contrary to the public concerns, the auditor independence is not weakened, rather maybe strengthened, when auditors provides non-audit services to the same clients. The results are consistent with previous studies, suggesting that the provision of both services to the same clients could improve the audit quality from a beneficial knowledge spillover between services. The regulators and policy authorities may have to be more cautious when they intend to prohibit auditors from supplying various non-audit services to the same clients.