위 선종과 선암종에 있어서 Carcinoembryonic Antigen (CEA)과 Epithelial Membrane Antigen (EMA)에 대한 면역조직화학적 연구

김혜숙,허만하,이선경,김혜숙,허만하,이선경 대한병리학회 1989 Journal of Pathology and Translational Medicine Vol.23 No.1

입원 환자용 초기 영양검색도구의 타당도 검증

김혜숙,이선희,김혜숙,권오란 한국영양학회 2019 Journal of Nutrition and Health Vol.52 No.4

Purpose: Poor nutrition in hospitalized patients is closely linked to an increased risk of infection, which can result in complications affecting mortality, as well as increased length of hospital stay and hospital costs. Therefore, adequate nutritional support is essential to manage the nutritional risk status of patients. Nutritional support needs to be preceded by nutrition screening, in which accuracy is crucial, particularly for the initial screening. To perform initial nutrition screening of hospitalized patients, we used the Catholic Kwandong University (CKU) Nutritional Risk Screening (CKUNRS) tool, originally developed at CKU Hospital. To validate CKUNRS against the Patient-Generated Subjective Global Assessment (PG-SGA) tool, which is considered the gold standard for nutritional risk screening, results from both tools were compared. Methods: Nutritional status was evaluated in 686 adult patients admitted to CKU Hospital from May 1 to July 31, 2018 using both CKUNRS and PG-SGA. Collected data were analyzed, and the results compared, to validate CKUNRS as a nutrition screening tool. Results: The comparison of CKUNRS and PG-SGA revealed that the prevalence of nutritional risk on admission was 15.6% (n=107) with CKUNRS and 44.6% (n=306) with PG-SGA. The sensitivity and specificity of CKUNRS to evaluate nutritional risk status were 98.7% (96.8~99.5) and 33.3% (28.1~39.0), respectively. Thus, the sensitivity was higher, but the specificity lower compared with PG-SGA. Cohen’s kappa coefficient was 0.34, indicating valid agreement between the two tools. Conclusion: This study found concordance between CKUNRS and PG-SGA. However, the prevalence of nutritional risk in hospitalized patients was higher when determined by CKUNRS, compared with that by PG-SGA. Accordingly, CKUNRS needs further modification and improvement in terms of screening criteria to promote more effective nutritional support for patients who have been admitted for inpatient care.

Bacillus Keratinase처리에 의한 정상모의 형태적 변화

김혜숙,최근희,강상모 한국미용학회 2009 한국미용학회 추계학술발표회 Vol.2009 No.1

환시와 심한 공간지남력 저하가 두드러진 단순헤르페스뇌염

김혜숙,김해종,강지윤,김은주,박경원 대한신경과학회 2012 대한신경과학회지 Vol.30 No.2

A 58-year-old woman was admitted to hospital due to memory impairment and visuospatial dysfunction. Brain revealed high signal lesions on both the temporal and inferior frontal lobes. She was diagnosed as having herpes encephalitis based on her clinical and laboratory findings. Twelve months later she still presented with disorientation, although her amnesia was improved. Neuropsychological testing revealed multiple impairments, and especially visuospatial dysfunction. This patient represents a case of herpes simplex encephalitis associated with spatial disorientation even when the amnesia had disappeared.

S . L . E . 환자 혈액에서 분리한 Listeria monocytogenes 의 세균학적 특성

김혜숙,정윤섭,이삼열 대한미생물학회 1973 大韓微生物學會誌 Vol.8 No.1

Listeria monocytogenes human infection is a relatively rare disease which usually is meningitis in newborn babies. The organism was isolated from blood cultures of a 52 year old female patient with meningitis. It was considered that the underlying disease, I.e. S.L.E., and the steroid therapy which the patient had been receiving played some role for the Listeria infection. The isoIate was showing characteristics of L. monocytogenes, I.e. diphtheroid like morphology, motility with four peritrichous flagella, hemolytic small colonies on blood agar, growth in the presence of 7. 5% salt and at 4 C, and inducing monocytosis in an experimentally infected rabbit. Serologically the organism was identified as L. monocytogenes 4b. The isolate was showing susceptibility to many antibiotics tested including ampicillin, penicillin and tetracycline which were the recommended drugs of choice for the treatment of Listeriosis. It is the general opinion that Listeriosis is not so rare as literatures are showing. It is considered that some of the isolate of the organism from clinical specimens are mistakenly discarded due to the fact that the organism shows diphtheroid like morphology and that not many laboratories are able to recognize the organism. Literatures are seen which emphasize more careful examination of gram positive bacilli with diphtheroid like morphology especially when they are isolated from blood or from spinal fluid of patient.

일제강점기 개성(開城)의 사월초파일 풍속과 개성상인의 활동

김혜숙 한국역사민속학회 2020 역사민속학 Vol.0 No.59

This paper aims to focus on the customs of Buddha's Birthday(四月初八日, April 8th on the lunar calendar) in Gaeseong(開城) during the Japanese colonial era. At that time. people of Gaeseong enjoyed Buddha's birthday festival the most magnificently and actively in Korean Peninsula, and It was considered as the most important holiday by the people of Gaeseong. Even though, men and women of all ages enjoyed the day regardless of religion, it was more special to ladies, children and merchants. Furthermore it was not only enjoyed by people in Gaeseong, but neighborhood residents. One of the reasons why Buddha's Birthday festival was more magnificently held, executed and passed down than other regions was because Gaeseong was the old capital of Goryeo(高麗, 918-1392) where designated Buddhism as the national religion. However, there were more important reasons, those were Gaeseong was the city where the tradition of Sijeon(市廛) business had existed since Goryeo period and organizational ability and active performance of Gaeseong merchants was lasting even in the Japanese colonial era. Except ginseng dealers, drapery products dealers such as Seonjeon(縇廛, silk dealer), Cheongpojeon(靑布廛, blue hemp cloth dealer) and Baekmokjeon(白木廛, white cotton dealer) were the biggest and the most powerful merchants which were also the leading group of Sijeon, and Budda’s Birthday was the highest season for them. Buddha's Birthday is April 8th on the lunar calendar and it is seasonally located in early summer, so in the pre-modern period, by this time people started to change their clothes which were suitable for summer. Therefore, the sales amount of fabrics to make clothes for holidays and summer, had been dramatically increased. To attract more customers, Gaeseong merchants made various efforts every year before and after Buddha's Birthday, including lantern decorations on commercial streets and downtown areas, all sorts of entertainment and play, giveaway offerings, and sales events. As the result of these, the regional scope of who visited Gaeseong on Buddha's Birthday to see these games and events was not limited to Gyeonggi-do and Hwanghae-do. Thanks to tens of thousands of people visiting, the sales amount had increased on Buddha's Birthday every year, not only for fabric dealers but also other industries’ dealers. Above all, the reason why Buddha's Birthday events were held in the Joseon style in Gaeseong was because of the characteristics of Gaeseong. In the Japanese colonial era, Gaeseong had smaller Japanese population and weaker economic power then the other cities of Joseon. The percentages of Koreans in the council of Gaeseong-bu(開城府) and the Chamber of Commerce and Industry were all inundant and the commercial supremacy of Gaeseong had been dominated by Koreans. Because Gaeseong merchants of the high stature were leading the city, Buddha's Birthday can be held according to the lunar calendar, contents of the festival could inherit the traditions of the late Joseon Dynasty, and Gaeseong was influenced by Japan later than other regions. 이 논문은 일제강점기 개성(開城) 지역의 사월초파일 풍속을 연구대상으로 한다. 당시 전국에서 가장 성대하고 활발하게 실행되었다는 개성의 사월초파일은 개성 사람에게는 1년 중 제일 큰 명절로 중시되었다. 종교와 상관없이 남녀노소가 즐겼다고는 하지만 개성에서 사월초파일은 특히 부인과 아이 그리고 상인의 놀잇날로 여겨졌다. 또한 개성 사람은 물론이고 인근의 주민들도 매년 기대하며 찾는 지역축제의 장이기도 했다. 이와 같이 개성에서 다른 지역보다 사월초파일이 성대하게 전승, 실행되었던 데는 개성이 불교를 국교로 하던 고려의 구도(舊都)였다는 지역사가 영향을 미쳤다. 하지만 그보다 중요한 요인은 개성이 고려시대부터 시전(市廛) 상업의 전통이 존재했던 상업도시였고, 조선의 대표상인으로 손꼽히던 개성상인(開城商人)의 조직력과 활약이 일제강점기까지도 유지되었다는 점이다. 특히 삼상(蔘商)을 제외하고 개성 시내에서 가장 규모가 크고 영향력이 있던 상인은 시전상의 주축이었던 포목상이었고, 이들에게 사월초파일은 중요한 대목이었다. 사월초파일은 계절적으로 초여름인데, 당시 조선의 의생활 관습상 이 즈음은 여름옷으로 갈아입기 시작하는 때였다. 따라서 사월 초부터 파일빔과 여름옷에 소용되는 옷감의 판매가 급증하였다. 이에 더 많은 고객을 유인하고자 개성상인은 사월초파일을 전후로 상가와 시내의 등 장식, 각종 여흥과 놀이 그리고 경품 제공 및 대매출 행사를 여는 등 매년 다각적인 노력을 기울였다. 그 결과, 사월초파일의 관등놀이와 유흥 행사를 보기 위해 개성을 찾는 사람의 지역 범위는 경기도와 황해도를 넘어섰고, 수만 명의 인파덕분에 해마다 사월초파일에는 포목상뿐 아니라 타 업종의 상인들도 매출이 증가하고는 했다. 또한 일제강점기 개성에서 조선적인 사월초파일 행사를 상인이 주도적으로 계속 설행할 수 있던 것은 개성의 지역적 특성 때문이었다. 당시 개성은 조선 내 다른 도시보다 일본인 거주자가 적고 경제력 또한 조선인 상인들이 월등히 우세했다. 그러다 보니 조선인 유력자층이 부회(府會), 상공회의소(商工會議所)를 주도하였고, 개성 내 상권도 장악하고 있었다. 이러한 까닭으로, 개성상인이 주도하는 개성의 사월초파일 풍속은 1930년대 후반까지도 양력을 강요당하는 대신 음력을 고수하고, 내용면에서도 조선 후기의 전통을 가장 온전하게 계승하며 일본의 영향을 비교적 늦게 받을 수 있었다.

칸트의 「순수이성비판」변증론에 나타난 이성의 역할

김혜숙 이화여자대학교 한국문화연구원 1990 韓國文化硏究院 論叢 Vol.57 No.-

Human reason has this peculiar fate that in one species of its knowledge it is burdened by questions which, as prescribed by the very nature of reason itself, it is not able to ignore, but which, as transcending all its powers, it is also not able to answer(A vii). With this phrase, Kant starts the Preface to First Edition. Those questions are what has been considered the preoccupation of the traditional metaphysics in the western philosophy. They are the questions about God, the immortality of the soul, and freedom. In the Transcendental Dialectic in the first Critique, Kant contends that the traditional metaphysics, especially within the rationalist tradition, makes an illegitimate claim to knowledge of what goes beyond the limit of human understanding and reason. Metaphysics, once entitled the Queen of all the sciences, now must be reinstituted as a tribunal of reason (i.e., as a critique of pure reason) which will dismiss all groundless pretensions and extravagances of reason to guard it against self-deceptions that give birth to despotic dogmatism. Thus conceived, metaphysics serves as a discipline for preventing errors and limiting the power of pure reason rather than for extending knowledge. Metaphysics for Kant has only a negative function to check the exaggeration of reason and its pure speculative use, and thus merely serves as a propaedeutic to metaphysics in its proper sense. In this essay, I examine Kant 's formulation of the function of reason concerning our knowledge Kant claims that reason in contrast to understanding only has a regulative function with regard to empirical knowledge, and that its constitutive use gives rise to a transcendental illusion on which traditional metaphysics is based. The concepts of reason, unlike the concepts of understanding, do not constitute the concepts of an object, but rather constitute the regulative ideas in accordance with which our empirical knowledge is organized, ordered, and given a direction. The essential function of these ideas is to maximize the systematicity within the body of our knowledge, which is made possible through the principles of reason. The ideas and the principles of reason then have a logical and methodological validity lacking an objective validity. They are valid subjectively-in view of reason itself. They serve the subjective interest of reason which lies in the pursuit of a certain possible perfection or complete systematization of our knowledge of objects. However, a problem arises when Kant claims that the logical principles of reason must presuppose a transcendental principle whereby a systematic unity achieved through the logical principles is a priori assumed to be necessarily inherent in the objects. What Kant claims is that the systematic unity of reason must be based on the unity in nature. Reason would otherwise run counter to its own vocation, proposing as its aim an idea quite inconsistent with the constitution of nature. Maintaining this, however, Kant takes the function of reason not merely to be regulative, but to be constitutive also. This makes Kant 's position in the first Critique incoherent. I argue that Kant 's attempt to ground the systematic unity of reason on the unity in nature in the first Critique is not compelling, though not a total failure. In order to make sense out of Kant 's claim about the necessity of the laws of reason, we must turn to the notion of the purposiveness of nature that is needed as a principle in our reflection on nature. In the third Critique (the Critique of Judgment), Kant holds that when we reflect upon natural things and phenomena, we must regard them as if some conscious being (whether it be God or not) made nature conform to our understanding of it. The purposiveness (Zweckmassigkeit) of nature is taken by Kant as an a priori concept originated from the reflective judgment. Given the conception of the purposive unity of nature as the principle of reflective judgment, then, Kant ' claim that the unity of reason must presuppose the unity of nature amounts to the laim that the unity of reason must be based on the principle of reflective judgment. But here the problem raised few paragraphs ago takes us one step backward to the question of the status of the principle of reflective judgment. (What secures the necessity of the principles of reason is the unity in nature which in turn is accounted for as the principle of reflective judgment.) I contend that this peculiar feature of Kant 's position concerning the necessity of the lawful function of reason is no more than the commonplace of Kant 's transcendental idealism.

모유수유 전화 상담 내용의 분석

김혜숙 한국간호과학회 1995 Journal of Korean Academy of Nursing Vol.37 No.2

This study was done to analysis data on breastfeeding mothers. This stud was conducted using data from telephone counseling in one metropolitan area. The subjects who had received consultation about breastfeeding were 100 breastfeeding mothers. The period of consultation was from Mar. 9, 1994 to August 23, 1994. Consultants were referred from UNICEF, hospitals, TV, newspapers or magazines. Analysis of the problem patterns resulted in 11 classifications. These were physio -anatomical factors(11 cases) , psychological factors(15 cases), breastfeeding methods(21 cases), breastfeeding intervals and frequency(19 cases) , disease in the breastfeeding mothers(13 cases), disease in the babies (12 cases), lack of support (4 cases), food and drugs while breastfeeding(5 cases), weaning(11 cases), others(27 cases). The highest frequency was for breastfeeding methods (21 cases). When the contents of the counselling were analyzed for the 100 cases, 36 problem patterns were identified. Patterns with over 10 responses were diarrhea, insufficient milk supply, sore and cracked nipples, weaning, inverted nipples and jaundice. The age of infants when mothers were telephoned was as below : 1 week(28 cases), 2 weeks(12 cases), 3-4 weeks(18 cases), 5-8 weeks(7 cases), 9 weeks-3 menths(4 cases), 4 menths-6 months(12 cases), over 6 months(2 cases), and the number of pregnant women was 12. The nursing diagnosis were classified according to problem patterns and each diagnosis was assigned an appropriate Problem Pattern The total number of nursing diagnoses was 22. When clients are referred for counselling nurses need guidelines about problems, possible causes and nursing. In this study, the example of guidelines for sore nipples is suggested. The recommendations based on the telephone counseling results are as follows : Prenatal education about the advantages of breastfeeding and breast care, and home visits after delivery for counseling related to breastfeeding. During the hospital stay, nursing intervention such as education on breastfeeding methods using slides, audio-visual tapes, pamphlets are needed as well as an initial trial of breastfeeding. Further research is indicated on the perceived lack of breast milk and on the effectiveness of nursing interventions to pro-mote breastfeeding.

지속가능 경영노력이 공공기관 성과에 미치는 영향연구 -조직구서원의 인식을 중심으로-

김혜숙 한국정책학회 2013 한국정책학회 학술대회 Vol.2013 No.4

베크라이트 合成에 관한 觸媒의 영향

金惠淑,金明玉,安秉律,李貞愛,任昌福,崔京子 이화여자대학교 사범대학 과학교육과 1967 과학교육 Vol.3 No.-