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구미진심과립(九味鎭心顆粒)의 불안장애 활용에 대한 중의학 연구 고찰
김천중 ( Cheon-jung Kim ),정서윤 ( Seo-yun Jeong ),김경옥 ( Kyeong-ok Kim ) 대한한방신경정신과학회 2018 동의신경정신과학회지 Vol.29 No.1
Objectives: The purpose of this study is to investigate the composition, origins, and utilization of Jiuwei Zhenxin Granules for anxiety disorders in Chinese medicine. Methods: Studies found in six databases were chosen, and major indicators were analyzed. Results: Jiuwei Zhenxin Granules are modified from Pyeonbojinsimdan on Taepyeonghyeminhwa-jegukbang. In Jiuwei Zhenxin Granule studies, there were significant effects in nine outcomes in twenty- four studies of primary anxiety disorders and seventeen outcomes were similar in effect to that in the control. Three outcomes in ten studies of secondary anxiety disorders showed significant effects, and five outcomes were similar in effect to that in the control. Conclusions: Jiuwei Zhenxin Granules is a prescription that focuses on harmony of vital energy (qi) and blood, and stability of mind. The significance of the constitution of Jiuwei Zhenxin Granules is similar to that of domestic anxiety disorder studies, so it seems to be applicable to anxiety disorders. With regard to domestic use of Jiuwei Zhenxin Granules, more research is needed on the dosage according to the formulation.
슐러주기 변경에 의한 김블형 관성항법장치 교정기법 연구
신용진,김천중,박정화,Sin, Yong-Jin,Kim, Cheon-Jung,Park, Jeong-Hwa 제어로봇시스템학회 2001 제어·로봇·시스템학회 논문지 Vol.7 No.10
Most of gimballed inertial navigation systems(GNIS) are calibrated periodically to maintain their inherent accuracy. The existing calibration techniques using the conventional schuler test with the least square method and the multiposition test take a long time and have some problems in procedures. To solve this problem, calibration method using a linear Kalman filter is proposed by us. In this paper, the calibration method by the change of Schuler period is studied in order to improve the calibration performance of the gimballed INS. First of all, it is shown that the observability of Kalman filter is also enhanced the Schuler period is decreased. Simulation results show that the calibration performance using the present scheme is improved according to the decrease of the Schuler period and the calibration time is shortened extremely, too. And our proposed technique shows desirable estimation performance for the g-sensitive errors of inertial sensors in particular.
비알코올성 지방간 세포 모델에서 소분청음의 지방증 완화 효능 연구
이혜인,김지수,김천중,김하나,양태준,정상준,최창원,Lee, Hye-in,Kim, Ji-su,Kim, Cheon-jung,Kim, Ha-na,Yang, Tae-jun,Jeong, Sang-jun,Choi, Chang-Won 대한한의학방제학회 2016 大韓韓醫學方劑學會誌 Vol.24 No.2
Objectives : The purpose of this study is to evaluate the anti-lipogenic effect of Sobuncheong-eum on non-alcoholic fatty liver disease in free fatty acid induced cellular model. Methods : HepG2 cells were treated with palmitate for 24h to overload intracellular triglyceride (TG) content in the presence or absence of Sobuncheong-eum extract. After palmitate treatment, Intracellular TG content was measured with TG assay kit. Several lipogenesis related markers, including AMP-activated protein kinase (AMPK), sterol regulatory element-binding transcription factor-1c (SREBP-1c), acetyl-CoA carboxylase (ACC), and fatty acid synthase (FAS), were assessed using Western-blot analyses and RT-PCR. Results : Palmitate markedly increased intracellular TG in HepG2 cells, and which were alleviated by coadministered Sobuncheong-eum extract. Sobuncheong-eum extract activated AMPK, which plays a key role in reducing hepatic lipid accumulation, and reduced lipogenic fators, SREBP-1c, ACC, and FAS. Conclusions : Taken together, it is conceivable that Sobuncheong-eum has an potential to alleviate steatosis, and which may be mediated by activating AMPK at least in part.
한방치료로 호전된 치골염이 의심되는 보행장애 환자 치험 1례
이혜인,나가영,김은지,김천중,양태준,정상준,위통순,최창원,Lee, Hye-in,Na, Ga-young,Kim, Eun-ji,Kim, Cheon-jung,Yang, Tae-jun,Jeong, Sang-jun,Wei, Tung-shuen,Choi, Chang-won 대한한의학방제학회 2016 大韓韓醫學方劑學會誌 Vol.24 No.4
Objectives : The purpose of this case is to investigate the effect of Korean Medicine on a patient who was suspected osteitis pubis. Methods : The patient was treated with herbal medicine, acupuncture, cupping therapy and physical therapy. We evaluated the results of the treatment by Hughes Scale and Visual Analogue Scale(VAS). Results : After treatment, the patient's symptoms were improved. Conclusions : These results show us that Korean medicine has effect on a patient who was suspected osteitis pubis.
김경옥 ( Kyeong-ok Kim ),김천중 ( Cheon-jung Kim ),서상일 ( Sang-il Seo ),김남열 ( Nam-yeol Kim ),김근우 ( Geun-woo Kim ) 대한한방신경정신과학회 2017 동의신경정신과학회지 Vol.28 No.3
Objectives: The aim of this study was to investigate the clinical studies which focus on acupuncture`s effect on anxiety disorder. Methods: We selected clinical studies through six databases. We then examined the characteristics of the selected studies and conducted an assessment for Risk of Bias (ROB). Results: Seventeen randomized-controlled trials were selected to determine the effects of acupuncture on anxiety disorders. We found that the risk of bias in most studies was unclear. The intervention of 7 seventeen randomized-controlled trials (RCT) was basic acupuncture, 8 RCT involved electric acupuncture, 2 RCT consisted of acupuncture and Moxibustion. Four of the 7 basic acupuncture RCTs and 5 of the 8 electric acupuncture RCTs had a significant effect on anxiety factors for anxiety disorders. Conclusions: Acupuncture treatment for anxiety disorders was found to be effective compared to the controls, or there was no difference in effectiveness compared to the controls. However, the quality of the included studies was low, and there only were a small number of studies. Therefore, well-designed studies and a greater number of the studies are needed.
갑상선 기능 저하증 환자에서의 혈중 Insulin과 C-peptide의 변화
이화영 ( Lee Hwa Yeong ),김광조 ( Kim Gwang Jo ),김천중 ( Kim Cheon Jung ),김병익 ( Kim Byeong Ig ),전우규 ( Jeon U Gyu ),이만호 ( Lee Man Ho ),정을순 ( Jeong Eul Sun ),이상종 ( Lee Sang Jong ) 대한내과학회 1993 대한내과학회지 Vol.44 No.1
Background : Studies for the effect of thyroid hormones on secretion of insulin and glucose metabolism have been reported, but those results appear to be controversial. Methods : We have investignated the levels of serum C-peptide and insulin following the oral glucose load in 19 patients with hypothyroidism and 14 normal subjects. Results : 1) T도 mean fating level of serum C-peptide in hypothyroidism was somewhat elevated. The response of serum C-peptide was significantly enhanced 2 hours after oral glucose tolerance test in hypothyroid patients (5.16±2.31 Vs 2.01±1.05 ng/ml) (p<0.05). 2) Serum insulin response was exaggerated after oral glucose tolerance test in hypothyroidism. (GTT 1 hour : 90.74±33.56 Vs 61.19±22.91uU/ml, GTT 2 hour : 74.23±36.47 Vs 49.30±0.83 uU/ml) (p<0.05). 3) Blood glucose response has been significantly augmented in hypothyroid patients after oral glucose tolerance test. (GTT 1 hour : 129.47±40.20 Vs 98.21±9.10mg/dl) (p<0.05). 4) The ratio of C-peptide to insulin had no significant difference between patients with hypothyroidism and normal subjects statistically. Conclusion : These results suggested that the slowing of C-peptide and insulin degradation due to hypometabolism in hypothyroidism could be contributed to higher serum levels of the C-peptide and insulin.