청소년의 PC중독

김진숙,최수미,강진구 한국청소년상담원 2000 청소년상담문제연구보고서 Vol.- No.-

요술 안개 외 3편

김진숙 고요아침 2018 한국동시조 Vol.- No.9

달빛 동물원 외 3편

김진숙 고요아침 2019 한국동시조 Vol.- No.14

Bacillus sp.에 의한 생물계면활성제의 생산 및 그의 성질

김진숙,방원기,정남현,송희상 한국응용생명화학회 2005 Journal of Applied Biological Chemistry (J. Appl. Vol.48 No.2

A bacterium capable of emulsifying hydrocarbon, n-hexadecane, and decreasing surface tension of the culture media using oil collapsing method was isolated. The bacterium was partially identified as Bacillus sp. and named BJS-51. n-Hexadecane was the most effective carbon source for production of biosurfactant. Surface tension was decreased from 76 dyne/cm to 31 dyne/cm and CMD (critical micelle dilution) had the highest value of 5.7 at 3% n-hexadecane. Ammonium phosphate was the most effective nitrogen source, when C/N ratio was 60, surface tension and CMD were 29 dyne/cm and 9.2, respectively. Optimum pH and temperature were 7.2 and 30oC, respectively. Produced biosurfactant was extracted and purified using organic solvent extraction method and preparative HPLC systems. After analysis by various color reaction, this biosurfactant was identified as lipopolysaccharide. Surface tension and CMC (critical micelle concentration) of purified biosurfactant were 27 dyne/cm and 0.08 g/l, repectively. CMD was 9.2, so the yield of biosurfactant was about 0.74 g/l at the optimal conditions. The biosurfactant was very stable at wide range of pH 2~12 with surface tension 29~31 dyne/cm and showed 29~30 dyne/cm of surface tension after heat treatment at 100oC for 60 min. 토양 시료로부터 n-hexadecane 대사능을 가지며 배양액의 표면장력을 감소시키고, 탄화수소를 가장 잘 유화시키는 세균을 oil-film collapsing 방법을 통해 선별하였다. 세균은 Bacillus sp.로 부분동정되었으며, BJS-51로 명명하였다. 생물계면활성제의 최적 생산에는 n-hexadecane이 가장 효과적인 탄소원이었으며, 3%의 농도일 때 표면장력이 76 dyne/cm에서 31 dyne/cm로 감소하였다. 이 때, CMD(critical micelle dilution)가 5.7로 가장 높았다. 질소원으로는 (NH4)2HPO4가 가장 효과적이었으며, C/N ratio가 60인 경우 표면장력이 29 dyne/cm, CMD가 9.2로 가장 활성이 좋았다. 생산 최적 pH는 7.2였으며, 최적 온도는 30oC였다.Bacillus sp. BJS-51에 의해 생산된 생물계면활성제를 유기용매 추출법과 preparative HPLC systems을 통해 추출, 정제하였다.각종 발색 시약으로 정제된 생물계면활성제의 생화학적 성질을 조사한 결과, 지질다당임을 확인 할 수 있었다. 생산된 생물계 면활성제의 표면장력은 27 dyne/cm까지 감소하였으며,CMC(critical micelle concentration)는 0.08 g/l였다. 상기의 최적 조건에서 생물계면활성제의 생산량은 CMD값이 9.2이었으므로 약 0.74 g/l이었다. 생산된 생물계면활성제는 pH 2~12 사이에서 표면장력 29~31 dyne/cm로 안정하였으며, 100℃에서 60분간 열을 가한 후에도 표면장력 29~30 dyne/cm로 안정하였다.

한국에서의 산업마케팅

김진숙 이화여자대학교 경영연구소 1999 신산업경영저널 Vol.17 No.1

급성 저주파수 난청 치료에 따른 이명의 양상 및 예후

김진숙,이은성,남의철 한국청각언어재활학회 2018 Audiology and Speech Research Vol.14 No.1

Purpose: Acute Low-frequency sensorineural Hearing Loss (ALHL) is characterized by earfullness, tinnitus and hearing loss restricted to the low frequency region. The aim of this study was to investigate the characteristics and prognosis of tinnitus in ALHL. Methods: We investigated tinnitus characteristics with analyzing tinnitograms and studied correlation between tinnitus improvement and hearing recovery of ALHL patients. We classified hearing change after the four weeks of medical treatment applying oral steroid and diuretics into ‘complete recovery,’ ‘partial recovery,’ and ‘no change.’ Degree of tinnitus improvement following the treatment was categorized as ‘completely disappeared,’ ‘partially improved,’ and ‘persistent.’ Results: Among 46 ALHL patients, tinnitus was reported by 34 (74.0%) patients. After the medical treatment tinnitus completely disappeared in 19 (55.9%), partially improved in 9 (26.5%), and persisted in 6 (17.6%). Among 26 patients who completed tinnitograms, tinnitus was matched at frequencies ≤ 500 Hz in 14 (53.8%) and at ≥ 2,000 Hz in 12 (46.2%), respectively, forming lower and higher frequency tinnitus groups. Tinnitus completely disappeared or partially improved in 12 (85.7%) patients with lower frequency tinnitus and in 9 (75.0%) with higher frequency tinnitus. We observed a significant positive correlation between hearing recovery and tinnitus improvement in both lower and higher frequency tinnitus groups (r = 0.74 and r = 0.62, respectively). Conclusion: Patients with ALHL may complain the high frequency tinnitus although their hearing loss recently developed in low frequency region. Tinnitus associated with ALHL was successfully treated with applied medications, showing better treatment for lower frequency tinnitus group. Hearing recovery and tinnitus improvement were significantly correlated.

소음환경에서 표적단어의 예상도가 조절된 한국어의 문장검사목록개발 시안

김진숙,배소영,이정하 한국음성과학회 2000 음성과학 Vol.7 No.2

This paper describes a test of everyday speech understanding ability, in which a listener;s utilization of the context-situational information of speech is assessed, and is compared with the utilization of acoustic-phonetic information. The test items are sentences which are presented in a babble type of noise, and the listener response is the key word in the sentence. The key words are alwayd two-syllabic nouns and the questioning sentences are added to obtain the responding key words. Two types of sentences are used. One is the high-predictable sentences for which the key word is somewhat predictable from the context. The other is the low-predictable sentences for whih the key-word cannot be predicted from the context. Both types are included in six 40-item forms of the test, which are balanced for intelligibility, key-word familiarity and predictability, phonetic content, and length. Performance of normally hearing listeners shows significantly different functions for various signal-to-noise ratios. The potential applications of this test, particularly in the assessment of speech understanding ability in the hearing impaired, are discusse. Keywords : speech, context-situational, acoustic-phonetic, high-predictable, low-predictable.

차원감소 단어벡터 시각화를 통한 어휘별 관계 분석

고광호(Kwang-Ho, Ko),백주련(Juryon, Paik) 한국컴퓨터정보학회 2022 한국컴퓨터정보학회 학술발표논문집 Vol.30 No.1

고위험병원체 결핵균의 신속진단을 위한 액체배양시스템 평가

김진숙,김승철,전보영,박승규,Kim, Jin-Sook,Kim, Seung-Cheol,Jeon, Bo-Young,Park, Seung-Kyu 한국미생물학회 2009 미생물학회지 Vol.45 No.3

본 연구에서는 객담 내 결핵균의 배양시험과 약제 감수성 시험 방법으로서 BacT/Alert 액체 배지, Ogawa 배지 및 $L\ddot{o}wenstein$-Jensen 배지 배양법을 비교하였다. 신속 액체배양시스템은 기존의 Egg-based media (Ogawa, $L\ddot{o}wenstein$-Jensen 배지)에 비해 높은 민감도와 빠른 배양으로 결핵환자의 초기 객담 검사와 약제 감수성 시험에 널리 사용되어 왔다. 객담은 N-Acetyl-L-cystine과 4% NaOH로 처리한 후 BacT/Alert 액체 배지 시스템과 Ogawa 배지에 접종하고 배양하여 비교하였다. 결핵환자 객담 검체 135개 중 도말검사결과 양성은 95개였고, Ogawa 배지 배양결과 양성으로 확인된 수는 89개(65.9%)였으며, BacT/Alert 액체 배지에서는 97개(71.9%)가 양성으로 확인되었다. 결핵균 배양 양성 검체의 평균배양일은 Ogawa 배지에서 22.4일, BacT/Alert 액체 배지는 11.3일로 단축되는 것을 확인하였다. 약제 감수성 시험에는 32개 결핵균주를 이용하였으며, isoniazid를 첨가한 BacT/Alert 액체 배지와 $L\ddot{o}wenstein$-Jensen 배지에서의 약제 감수성 시험 검사결과 일치률은 87.5%를 보였고, rifampicin에서의 일치률은 90.6%로 나타났다. In this study, we compared the BacT/Alert liquid culture system with Ogawa and $L\ddot{o}wenstein$-Jensen (L-J) media for sputum culture and drug susceptibility test (DST) of Mycobacterium tuberculosis. Rapid liquid culture systems have been widely employed both for primary cultures of M. tuberculosis from clinical specimens and for drug susceptibility test because of its greater sensitivity and faster turn-around time than the conventional egg-based culture methods (Ogawa, $L\ddot{o}wenstein$-Jensen media). Sputum specimens were decontaminated with N-acetyl-L-cysteine (NALC)-4% NaOH and inoculated into the BacT/Alert culture bottles and Ogawa media. 95 from among 135 sputa were smear-positive, 97 (71.9%) were culture-positive by the BacT/Alert culture system, while 89 (65.9%) were positive by Ogawa media. The mean time to culture-positive by the BacT/Alert process system was about 11.3 days, which was significantly shorter than that by Ogawa media (22.4 days). Of 32 M. tuberculosis cultures examined for drug sensitivity, the concordant rate between the two methods (BacT/ Alert liquid culture system, $L\ddot{o}wenstein$-Jensen media) ranged from 87.5% for isoniazid and 90.6% for rifampicin.

미국 원격의료 주별 정책 현황과 한국에의 시사점

김진숙,오수현,최재욱,김석영 대한의사협회 2015 대한의사협회지 Vol.58 No.10

The main objective of this study to propose an implementation about telemedicine policy in Korea through analyzing current status of state telemedicine policy in the United States. To achieve the result, three types of data sets were used to draw conclusions; 1) status of insured service of telemedicine in each state, 2) physician practice standards related to telemedicine, and 3) licensure. Analyzed results indicated differentiation in insured status of telemedicine service among private insurance parity law, medicaid coverage parity law, and state employee health plan parity in each states. Only two states provide insured service of telemedicine without any limits or certain conditions. Other states have a strict regulation or coverage condition about providing insurance. Each states also apply rigorous standards to telemedicine providers about physician practice standards and licensure. Some states restrict telemedicine itself or provide strict regulation process of telemedicine in Physician-patient encounter. Also, the most strict type ‘full state license’ and ‘consulting exemptions (applied in certain condition)’ are applied in most of states. On the basis of study result, environmental and conditional requirement implementation in application of telemedicine policy in Korea is provided in conclusion.