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김지원,정희경,이주영,김광휘,김태연,이태걸,김동은,Kim, Ji-Won,Jeong, Hu-Gyeong,Lee, Joo-Young,Kim, Kwang-Hwi,Kim, Tae-Yeon,Lee, Tae-Geol,Kim, Dong-Eun 대한한방안이비인후피부과학회 2017 한방안이비인후피부과학회지 Vol.30 No.4
Objectives : The purpose of this study is to investigate recent clinical studies on the effect of acupuncture on hearing loss. Methods : Based on the PubMed search with the key search terms of 'hearing loss, acupuncture', dated from 2004 to 2017, 1 controlled trials, 3 case reports and 3 case series was found, and were analyzed for this study. Results : 1. The most commonly used acupoints were Shuaigu(GB8) and Fengchi(GB20). 2. The most commonly used meridians were the du channel, the gall bladder meridian of foot-shaoyang, and the triple bunner meridian of hand shaoyang. 3. Acupuncture treatment was effective for conductive and sensorineural hearing loss, especially sudden sensory neural hearing loss. 4. More clinical studies are needed to prove the effectiveness of the acupuncture on hearing loss. To be more objective on the study results, we can measure auditory brainstem response for hearing loss after acupuncture treatment.
한국인에서 조현병과 Cannabinoid Receptor 1 유전자의 삼핵산 반복서열의 연합에 대한 연구
김지원,노양호,김민재,김채리,박병래,배준설,신형두,최인근,한상우,황재욱,우성일,Kim, Ji-Won,Roh, Yang-Ho,Kim, Min-Jea,Kim, Chea-Ri,Park, Byung-Lae,Bae, Joon Seol,Shin, Hyoung Doo,Choi, Ihn-Geun,Han, Sang-Woo,Hwang, Jaeuk,Woo, Sung-Il 대한생물정신의학회 2014 생물정신의학 Vol.21 No.3
Objectives Previous studies suggest that the cannabinoid receptor 1 (CNR1) gene could be an important candidate gene for schizophrenia. According to linkage studies, this gene is located on chromosome 6q14-q15, which is known to harbor the schizophrenia susceptibility locus (locus 5, SCZ5, OMIM 803175). The pharmacological agent delta-9-tetrahydrocannabinol (${\Delta}$-9-THC) seems to elicit the symptoms of schizophrenia. The association between CNR1 polymorphisms and schizophrenia is actively being investigated, and some studies have linked the AAT-trinucleotide repeats in CNR1 to the onset of schizophrenia. In this study, we have investigated the association between the AAT-trinucleotide repeats in CNR1 and schizophrenia by studying schizophrenia patients and healthy individuals from Korea. Methods DNA was extracted from the blood samples of 394 control subjects and 337 patients diagnosed with schizophrenia (as per the Diagnostic and Statistical Manual of Mental Disorders, fourth edition criteria). After polymerase chain reaction amplification, a logistic regression analysis, with age and gender as the covariates, was performed to study the variations in the AAT-repeat polymorphisms between the two groups. Results In total, 8 types of trinucleotide repeats were identified, each containing 7, 8, 10, 11, 12, 13, 14, and 15 repeats, respectively. $(AAT)_{13}$ allele was most frequently observed, with a frequency of 33.6% and 31.6% in the patient and control groups, respectively. The frequency of the other repeat alleles in the patient group (in the decreasing order) was as follows : $(AAT)_{13}$ 33.6%, $(AAT)_{14}$ 21.6%, $(AAT)_{12}$ 18.5%, and $(AAT)_{7}$ 11.1%. The frequency of the repeat alleles in the control group (in the decreasing order) was as follows : $(AAT)_{13}$ 31.6%, $(AAT)_{14}$ 24.5%, $(AAT)_{12}$ 17.2%, and $(AAT)_{7}$ 11.6%. However, there were no significant differences in the AAT-repeat polymorphisms of the CNR1 gene between the patient group and the control group. Conclusions Although our study revealed no significant association of the AAT-repeat polymorphism of the CNR1 gene with schizophrenia, it will serve as a good reference for future studies designed to examine the cannabinoid hypothesis of schizophrenia.
김지원,정홍영,김효희,권유리,엄광문,이정환,김경섭,전재훈,박병규,Kim, Ji-Won,Jeong, Hong-Young,Kim, Hyo-Hee,Kwon, Yu-Ri,Eom, Gwang-Moon,Lee, Jeong-Whan,Kim, Kyung-Seoup,Jun, Jae-Hoon,Park, Byung Kyu 대한의용생체공학회 2012 의공학회지 Vol.33 No.4
Elderly women are reported to have greater risk of falls. The purpose of this paper was to investigate the possible gender differences in the reaction performance of ankle joint muscles, which have dominant role in the control of sagittal plane balance. Twenty-six elderly men and women with comparable mean age participated in this study. Reaction times to the audible beeps were measured in the tibialis anterior muscle and gastrocnemius muscle. Reaction time variables included premotor time, electromechanical delay and total reaction time. Gender difference in each reaction time was investigated by independent t-test. In both muscles, premotor time was longer in men but the electromechanical delay was longer in women (p < 0.05). Resulting total reaction time was longer in men in tibialis anterior muscle (p < 0.01) and it tended to be longer in men also in gastrocnemius muscle (p = 0.25). The results demonstrates that the overall reaction performances of elderly women is better than or comparable to those of elderly men in ankle joint muscles. This suggests that the reaction performance of ankle muscles is hardly the cause of the greater risk of falls in elderly women.
김지원,Kim, Ji-Won 대한출판문화협회 1991 출판저널 Vol.92 No.-
국립국어연구원이 가장 정열을 쏟는 사업은 "종합국어대사전"의 편찬이다. 안병희원장은 이 사전이 통일을 앞두고 남북한언어의 깊은 골을 메우는 기초공사로서의 의의를 갖는다는 데 비중을 두는데, 일단 올해는 기초자료 확보에 진력하기로 하고 내년부터 본격착수에 들어가 2001년에 완간시킨다는 장기계획을 세워두고 있다.
저자 초대-"한국의 금속공예" 펴낸 이호관 문화재전문위원
김지원,Kim, Ji-Won 대한출판문화협회 1997 출판저널 Vol.223 No.-
금속을 재료로 한 우리 선조들의 유물에는 장인정신이 담긴 기품과 정교함이 깃들어 있다. 그 섬세한 예술혼을 따라 한국의 금속공예에 평생의 연구집념을 바쳐 오롯한 결실을 맺은 이호관씨의 저서는 금속공예를 다룬 국내 첫 저술이라는 점에서 더욱 의미가 깊다.