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김종철 충남대학교 의과대학 지역사회의학연구소 1997 충남의대잡지 Vol.24 No.1
Ovarian granulosa cell tumor (GCT) is one of the hormone-secreting sex cord stromal tumors and comprises approximately 2-3% of all ovarian tumors. Retrospective analysis of radiologic findings (ultrasonography, computed tomography, and magnetic resonance imaging, etc.) of pathologically proven eleven ovarian GCTs in ten patients was done for the orgin site, staging, largest diameter, margin, solid (enhancement degree) and/or cystic components, and associated endometrial hyperplasia, ascites, local and/or distant metastases. The purpose of this study was to evaluate whether there were any specific radiologic findings of these tumors. Nine patients had unilateral GCTs, and one patient had bilateral ovarian GCTs. Of total eleven GCTs, eight were of adult type and three were of juvenile thpe. the largest diameters of GCTs ranged form 1 to 26 cm (mean, 15.5 cm), Eight tumors were well-defined. One small tumor was solid, and two tumors were cystic (multilocular or unilocular). Eight tumors were mixed ones of both soft tissue componets and some cystic components: of these tumors, two tumors had hemorrhagic and necrotic portions, and four had multilocular of bilocular cystic portions. Metastatic nodules in the liver, invasion to uterus or rectum, omental or pelvic lymphadenopathy were observed in four patients. Ascites was found in six patient. Endometrial hyperplasia was associated with GCTs in two patients. Ovarian GCTs had radiologic findings of well-defined encapsulated soft tissue masses with some hemorrhagic, multiloucular cystic, or vocal cystic components, in association with endometrial thickening, ascites, and local and/or distant metastasis. These findings, in combination with clinical ones, may be useful to diagnose and follow ovarian GCTs.