건성안에서의 항산화 및 염증 억제 기능성 복합식품의 효과

김재훈,김호영,류양환,전연숙,유인천,윤경철,김재찬,Jae Hoon Kim,Ho Young Kim,Yang Hwan Ryu,Yeoun Sook Chun,In Cheon You,Kyoung Chul Yoon,Jae Chan Kim 대한안과학회 2008 대한안과학회지 Vol.49 No.9

Purpose: To evaluate the effect of Optibiol®, which is composed of multiple anti-oxidative and anti-inflammatory dietary elements, on the symptoms, clinical manifestations, and expression of various inflammatory cytokines in dry eye patients. Methods: Patients suffering from dry eye were given Optibiol® for 3 months. They completed questionnaires regarding dry eye symptom and underwent slit lamp biomicroscopic examinations, tear film breakup times, Shirmer tests, and conjunctival fluorescein staining examinations on a monthly basis during the intake of Optibiol®. Sampling of serum and tears was conducted at baseline and 3 months after taking Optibiol®, and various inflammatory cytokines in the serum and tears were measured with multiplex bead immunoassay. Result: Sixty-three patients were included in this study. After taking Optibiol®, the dry eye symptoms, Schirmer scores, tear film breakup times, and conjunctival staining scores (Oxford scale) showed significant improvement, and the expression of most inflammatory cytokines had decreased: in particular, IL-1β and MIP-1β in serum, and IL-17 and MIP-1β in tears were significantly lower. Conclusions: Optibiol®, an anti-oxidative and anti-inflammatory functional dietary supplement, is an effective dietary supplement in patients with dry eye syndrome. We posit that the decreased expression of inflammatory cytokines is an important mechanism in this effect. J Korean Ophthalmol Soc 2008;49(9):1397-1405

경련만으로 발현된 중대뇌동맥 분지부의 미파열성 거대 동맥류 - 증례보고 -

김재훈,이형중,김광명,김재민,김영수,고용,오성훈,오석전,Kim, Jae Hoon,Yi, Hyeong Joong,Kim, Kwang Myung,Kim, Jae Min,Kim, Young Soo,Ko, Yong,Oh, Seong Hoon,Oh, Suck Jun 대한신경외과학회 2001 Journal of Korean neurosurgical society Vol.30 No.5

Intracranial giant aneurysms have been known to cause clinical signs and symptoms, either by rupture, compression of surrounding structures, repeated minor leakage, or cerebral ischemia due to thromboembolism. A giant aneurysm which manifests only a seizure disorder comprises relatively few contributions. The authors present a case of a giant, unruptured aneurysm solely presenting with generalized tonic-clonic type seizure in a 43-year-old man. Brain computed tomogram(CT) and 3-D CT angiogram demonstrated a huge calcified aneurysm at the bifurcation of right middle cerebral artery. Complete neck clipping and aneurysmectomy followed by uneventful neurologic recovery.

플라즈마 조사에 의한 전기분무합성 SiO₂ 코팅층의 물접촉각 변화

김재훈,이준성,김지영,김상섭,Kim, Jae-Hun,Lee, Junseong,Kim, Ji Yeong,Kim, Sang Sub 한국재료학회 2014 한국재료학회지 Vol.24 No.11

Hydrophilic $SiO_2$ layers were obtained by the atmospheric-pressure plasma treatment. Superhydrophobic $SiO_2$ layers were first deposited by the electrospray deposition method. The electrospunable solution that was prepared based on the solgel method was sprayed on Si (100) substrates. The surface of the electrosprayed $SiO_2$ layers consisted of the agglomeration of nano-sized grains, which led to a very high roughness and revealed a very high contact angle to water droplets over $162^{\circ}$. After having been exposed to the atmospheric $Ar/O_2$ plasma, the observed superhydrophobicity of the $SiO_2$ layers were greatly changed: a dramatic variation of the water contact angle from $162^{\circ}$ to $3^{\circ}$, namely realization of superhydrophillicity. Interestingly, the surface microstructure was almost preserved. According to the XPS analysis, it is more likely that thanks to the plasma exposure, the surface of $SiO_2$ layers will be cleaned in terms of organic species that are hydrophobic-inducing, consequently leading to the hydrophilic nature observed for the plasma-exposed $SiO_2$ layers.

내경-후교통 동맥류 수술시 전 상상돌기 절제 유무에 대한 술전 혈관조영술의 의의

김재훈,김재민,이형중,백광흠,김충현,오석전,Kim, Jae Hoon,Kim, Jae Min,Yi, Hyeong Joong,Bak, Koang Hum,Kim, Choong Hyun,Oh, Suck Jun 대한신경외과학회 2000 Journal of Korean neurosurgical society Vol.29 No.9

Objective : Internal carotid-posterior communicating artery(IC-PC) aneurysms can be clipped easily without any special preparations. Occasionally, however, it is difficult to clip the low-lying IC-PC aneurysms without some kinds of additional procedures. Clinical Material and Methods : We experienced four cases of low-lying IC-PC aneurysms, which the intradural anterior clinoidectomy and/or anterior petroclinoid fold(APF) resection was essential to expose the proximal side of the aneurysmal neck and/or proximal control. One patient harbored two low-lying IC-PC aneurysms bilaterally. The patients were divided into two groups according to the necessity of anterior clinoidectomy : Group I(n=4) that needed an intradural clinoidectomy and/or APF resection and Group II(n=29) that had IC-PC aneurysms, easily clipped without any special preparation. Also, various radiometric parameters were measured through the preoperative angiograms. Results : The incidence of such aneurysms was 12% among a total of thirty-three surgically treated IC-PC aneurysms during lasr 3 years. Among four cases, three cases presented with subarachnoid hemorrhage and all aneurysmal sac projected to postero-inferior direction. In our study, We initially considered the necessity of intraoperative anterior clinoid process(ACP) removal and/or resection of APF in cases of shorter distance less than 5.6mm between the proximal aneurysmal sac and tip of the ACP(p<0.001), and the proximal portion of aneurysmal neck has located below the interclinoid line(p=0.001). Conclusion : Through a careful preoperative evaluation, some radiometric parameters can be used to determine whether the ACP should be removed in clipping of the low-lying IC-PC aneurysms. Unlike to total removal of the ACP, the intradural partial anterior clinolidectomy and/or APF resection, which are more familiar to surgeons, reduce the risks of the premature rupture, operative time, and also contribute a more precise clip placement with proximal control than the extradural clinoidectomy.

RFCVD 장치를 이용하여 성장한 실리콘 나노와이어의 특성

김재훈,이형주,신석승,김기영,고춘수,김현숙,황용규,이충훈,Kim, Jae-Hoon,Lee, Hyung-Joo,Shin, Seok-Seung,Kim, Ki-Young,Go, Chun-Soo,Kim, Hyun-Suk,Hwang, Yong-Gyoo,Lee, Choong-Hun 한국전기전자재료학회 2007 전기전자재료학회논문지 Vol.20 No.2

We have synthesized silicon nanowires by using RFCVD(Radio Frequency Chemical Vapor Deposition) system on Au deposited p-type Si(100) wafers, and investigated their physical and electrical properties. The silicon nanowires had been grown in the atmospheres of $H_{2},\;N_{2}\;and\;SiH_{4}$ at 10 Torr at the substrate temperatures of $700{\pm}5^{\circ}C\;and\;810{\pm}5^{\circ}C$ respectively. FE-SEM analysis revealed that diameters of the silicon nanowires are $50{\sim}60nm$ with the length of several ${\mu}m$. XRD analysis showed that the growth direction of the nanowires is Si[111]. Field emission characteristics showed that the turn-of voltages at the current of $0.01\;mA/cm^{2}$ are $10\;V/{\mu}m\;and\;8.5\;V/{\mu}m$ for the wires grown at $700{\pm}5^{\circ}C\;and\;810{\pm}5^{\circ}C$, respectively.

Effects of Acupotomy Treatment on Relapsed Lateral Malleolar Bursitis: A Case Report

김재훈,이정희,이윤규,이현종,김재수,Kim, Jae Hoon,Lee, Jung Hee,Lee, Yun-Kyu,Lee, Hyun-Jong,Kim, Jae Soo Society for Meridian and Acupoint 2019 대한침구의학회지 Vol.36 No.4

Objectives : This study details on a case of acupotomy for relapsed lateral malleolar bursitis. Methods : A 71-year-old woman with lateral malleolar bursitis was treated with acupotomy twice in an outpatient setting. A sterilized, disposable, blade width 0.5 mm × needle length 50 mm sized acupotomy was administered on GB40 and BL62 on each visit. Pain intensity assessment using Numeric Rating Scale (NRS) and the response evaluation criteria was conducted right after each treatment. Results : Pain on NRS declined from 5 to less than 1 after twice of acupotomy treatment. This result was regarded as 'Complete Response' using the response evaluation criteria. There were no side effects during whole treatment procedure at all. Conclusions : It is turned out that acupotomy can have a positive clinical effect on lateral malleolar bursitis in this case without any adverse effect. Further controlled studies on acupotomy for lateral malleolar bursitis are required for clinical application.

시간지연과 입력포화를 갖는 T-S 퍼지 카오스 시스템의 동기화

김재훈,신현석,김은태,박민용,Kim Jae-Hun,Shin Hyunseok,Kim Euntai,Park Mignon 대한전자공학회 2005 電子工學會論文誌-SC (System and control) Vol.42 No.1

본 논문에서는 시간지연과 입력포화를 갖는 카오스 시스템에 대한 퍼지 모텔 기반의 동기화 기법을 제안한다. 시간지연을 갖는 카오스 마스터 시스템과 슬레이브 시스템을 모델링하기 위해 Takagi-Sugeno(T-S) 퍼지 모델을 이용한다. 특히 슬레이브 시스템은 제어 입력이 제한되는 입력포화 특성을 갖는다고 가정한다. 선형 오차 피드백과 병렬 분상 보상(PDC) 방법에 따라 퍼지 카오스 동기화 시스템을 설계하고 동기화 오차 시스템의 국소 안정도 조건을 해석한다. 신호 전송 채널에는 시간지연이 항상 존재하므로 채널 시간지연 또한 고려한다. 입력포화와 시간지연을 갖는 퍼지 동기화 시스템의 국소 안정도에 대한 충분 조건은 Lyapunov-Krasovskii 이론을 적용하여 선형 행렬 부등식 (LMI) 문제의 해를 통해 얻어진다. 제안된 동기화 기법의 효과를 확인하기 위해서 모의 실험을 수행한다. This paper presents a fuzzy model-based approach for synchronization of time-delay chaotic system with input saturation. Time-delay chaotic drive and response system is respectively represented by Takagi-Sugeno (T-S) fuzzy model. Specially, the response system contains input saturation. Using the unidirectional linear error feedback and the parallel distributed compensation (PDC) scheme, we design fuzzy chaotic synchronization system and analyze local stability for synchronization error dynamics. Since time-delay in the transmission channel always exists, we also take it into consideration. The sufficient condition for the local stability of the fuzzy synchronization system with input saturation and time-delay is derived by applying Lyapunov-Krasovskii theory and solving linear matrix inequalities (LMI's) problem. A numerical example is given to demonstrate the validity of the proposed approach.

고로슬래그미분말을 혼입한 고유동콘크리트에서 골재조합이 콘크리트 유동성상에 미치는 영향에 관한 실험 연구

김재훈,윤상천,지남용,Kim, Jae-Hun,Yoon, Sang-Chun,Jee, Nam-Yong 한국건축시공학회 2003 한국건축시공학회지 Vol.3 No.4

The purpose of study is to offer base data for high fluid concrete mix property, as grasp effect of aggregate to reach much more effect for producing high fluid concrete. For this study, there are three types of combined aggregates, river sand + river aggregate(type A), river sand + crusted aggregate(type B), washed sea sand + crushed aggregate(type C) and take a factor, water-contents, water-binder ratio and S/a. And so, we had following conclusion, resulting application-ability of high fluid mortar by K-slump tester to use a handy consistency measuring instrument. And so, we had following conclusion, resulting application-ability of high fluid concrete by K-slump tester to use a handy consistency measuring instrument. 1) In cafe of regular water binder ratio, high fluid concrete suffered much effect of combined aggregates and water binder ratio. Range of water binder ratio by combined aggregates is w/b 0.4 downward(type A and B), w/b 0.35 downward(type C). 2) Water contents to need for producing high fluid concrete is minimum 170kg/$\textrm{m}^3$ without regard to combined aggregates. 3) The effect of S/a on high fluid concrete by combined aggregates is approximately S/a 50% (type A and B), s/a 50-55% (type C). 4) Consistency measuring of high fluid concrete by K-slump tester is possible and first indication value, high fluid concrete can be produced, is 6~10.5cm.

주어진 회전 수열에 대한 최소 히스토그램

김재훈,Kim, Jae-hoon 한국정보통신학회 2019 한국정보통신학회논문지 Vol.23 No.9

히스토그램 H는 가장 왼쪽 수직 에지와 가장 오른쪽 수직 에지를 연결하는 기저라고 불리는 하나의 수평 에지를 가진 x-단조 직교 다각형이다. 여기서 직교 다각형은 수평과 수직 에지들만을 가진 다각형이고, x-단조 다각형 P는 x-축에 수직인 모든 직선이 P와 많아야 두 번 교차하는 성질을 만족하는 다각형이다. 히스토그램 H의 테두리 선을 따라 반시계방향으로 움직이면, 꼭짓점에서 왼쪽 회전과 오른쪽 회전의 수열을 얻는다. 역으로, 꼭짓점에서의 회전들로 이루어진 수열이 히스토그램에 의해서 구현될 수 있다. 이 논문에서 우리는 주어진 회전 수열을 구현하는 히스토그램을 찾는 문제를 다룬다. 특별히 면적을 최소화하는 히스토그램과 구속 상자를 최소화하는 히스토그램을 찾을 것이다. 두 문제 모두 선형 시간 알고리즘들에 의해 풀리는 것을 보일 것이다. Histogram H is an x-monotone rectilinear polygon with a horizontal edge, called by a base, connecting the leftmost vertical edge and the rightmost vertical edge. Here the rectilinear polygon is a polygon with only horizontal and vertical edges and the x- monotone polygon P is a polygon in which every line orthogonal to the x-axis intersects P at most twice. Walking counterclockwise on the boundary of a histogram H yields a sequence of left turns and right turns at its vertices. Conversely, a given sequence of the turns at the vertices can be realized by a histogram. In this paper, we consider the problem of finding a histogram to realize a given turn sequence. Particularly, we will find the histograms to minimize its area and its bounding box. It will be shown that both of the problems can be solved by linear time algorithms.

동일선상 위치들에 대한 지도 레이블링

김재훈,Kim, Jae-hoon 한국정보통신학회 2020 한국정보통신학회논문지 Vol.24 No.10

지도에서 특별한 지형지물에 이름이나 설명문에 해당하는 레이블을 붙이는 것을 지도 레이블링(map labeling)이라고 한다. 본 논문에서는 직선상에 n개의 점들이 주어지고 점들에 대한 직사각형의 레이블을 위치시키는 문제를 다룬다. 특별히 레이블들의 높이는 모두 같고, 점들이 위치한 직선의 위쪽에 아래 변들이 모두 동일 선 위에 위치하도록 놓는다. 그리고 점과 레이블을 꺾은선으로 연결하고 이것을 지시선이라 부른다. 지시선은 수직선만으로 구성된 직선 지시선과 수직선, 수평선, 수직선으로 구성된 꺾인 지시선으로 나뉜다. 문제는 꺾인 지시선의 수를 최소화하도록 레이블을 위치시키는 것이고, 우리는 O(nlogn) 시간 알고리즘을 제안함으로서 [13]에서 제안한 O(n2) 시간 알고리즘을 개선한다. In a map, placing the labels, corresponding to names or explanations of specific features, is called map labeling. In this paper, n points on a line are given, and placing rectangular labels for the points is considered. Particularly, the labels have a same height and their lower sides lie on a straight line in the upper of the line on which the given points are. The points and the labels are connected by polygonal lines, which are called leader lines. The leader lines are classified into straight leader lines and bended leader lines, where the straight leader line consists of only the vertical line and the bended leader line consists of vertical, horizontal, vertical lines. The problem is placing the labels to minimize the number of bended leader lines, and we propose an O(nlogn)-time algorithm, which improves the O(n2)-time algorithm previously provided in [13].