잣나무 약 배양에 의한 callus 유도

김재헌,노은운 한국임학회 1984 한국산림과학회지 Vol.65 No.1

잣나무의 雄花를 5月 18日~25日에 採取하여 四分子期에서 未成熟花粉에 이르는 段階의 葯을 培養한 結果 callus를 誘導하였다. G.D 基本培地에 BAP 0.1ppm 및 NAA 0.1~1ppm을 組合으로 處理한 培地에서 callus發生이 좋았으며, ½濃度의 M.S培地(Sucrose 2%, Agar 0.8%)에 BAP 0.1ppm과 NAA 0.5ppm을 加한 경우에도 좋았다. callus의 chromosome數는 12인 haploid도 있었으나 대부분 24로서 diploid였다. 生長이 旺盛한 callus는 體細胞에서 起因된 것으로 생각되어 앞으로 chromosome의 變異 等을 더욱 調査하여 ploidy의 특성을 究明할 수 있으리라고 생각된다.

신경가동성에 대한 신경생물학과 신경생역학적 이해

김재헌,육군창,배성수,Kim Jae-Hun,Yuk Goon-Chan,Bae Sung-Soo 대한물리치료학회 2003 대한물리치료학회지 Vol.15 No.2

Nervous system is clinically important, and involved in most disorders directly or indirectly. It could be injury and be a source of symptoms. Injury of central or peripheral nervous system injury may affect that mechanism and interrupt normal function. An understanding of the concepts of axonal transport is important for physical therapist who treat injury of nerves. Three connective tissue layers are the endoneurium, perineurium, epineurium. Each has its own special structural characteristics and functional properties. The blood supply to the nervous system is well equipped in all dynamic and static postures with intrinsic and extrinsic vasculation. After nerve injury, alternations in the ionic compression or pressures within this environment may interfere with blood flow and, consequently conduction and the flow of axoplasm. The cytoskeleton are not static. On the contrary, elements of the cytoskeleton are dynamically regulated and are very likely in continual motion. It permits neural mobility. There are different axonal transport systems within a single axon, of which two main flows have been identified : First, anterograde transport system, Secondly, retrograde transport system. The nervous system adapts lengthening in two basic ways. The one is that the development of tension or increased pressure within the tissues, increased intradural pressure. The other is movements that are gross movement and movement occurring intraneurally between the connective tissues and the neural tissues. In this article, we emphasize the biologic aspects of nervous system that influenced by therapeutic approaches. Although identified scientific information in basic science is utilized at clinic, we would attain the more therapeutic effects and develop the physical therapy science.

아마존 지역 PALSAR 다중편파 자료의 반사대칭성 특성

김재헌,윤선용,원중선 대한원격탐사학회 2018 大韓遠隔探査學會誌 Vol.34 No.6

This paper presents reflection symmetry of polarimetric SAR over the Amazon rainforest in terms of correlation coefficients between the pairs of HH- and HV-pol and VV- and VH-pol data by ALOS PALSAR. The reflection symmetry is defined as a non-zero correlation between HH- and HVpol and VV- and VH-pol over natural distributed targets, and is a fundamental assumption for cross-talk calibration coefficient computation and for three-component decomposition for polarimetric SAR data. The Amazon rainforest is especially one of the common global reference sites for the reflection symmetry. The correlation coefficients for the pairs of reflection symmetry obtained in this study range from 0.018 to 0.097. The results imply that there exists a non-negligible dependency between co-pol and cross-pol in the distributed natural targets, and consequently the non-zero correlation must be considered as a potential contribution to errors of spaceborne SAR polarimetry to some extent. 이 연구는 아마존 열대우림 지역에서 획득된 ALOS PALSAR 자료로부터 HH-편파 와 HV-편파 및 VV- 편파와 VH-편파 간의 상관계수를 구하였으며, 이로부터 다중편파 SAR의 반사대칭(Reflection Symmetry) 가정에 대한 분석결과를 보고한다. 반사대칭 가정은 다중편파 SAR의 균질한 자연 산란체에서 HH-편파와 HV-편파 및 VV-편파와 VH-편파는 서로 완전 독립적이며 0의 상관계수를 갖는다는 것으로, 이는 다중편파 SAR의 필수적인 cross-talk 보정 계수 획득과정뿐만 아니라 다중편파 SAR 신호의 3-성분 분석법 등의 활용과정에서 흔히 적용되는 가정이다. 특히 아마존 열대우림 지역은 다중편파 SAR의 반사대칭성 보정에 대표적으로 활용되고 있는 국제적 기준분석 지역이다. 분석결과 가정과는 달리 반사대칭 쌍들 간의 상관계수는 0.018에서 0.097의 범위를 나타냈으며, 이는 동종편파와 이종편파 신호 간에 완전 독립적이지 못하며 무시할 수 없을 정도의 상관관계가 존재한다는 것을 지시하였다. 따라서 이와 같은 0이 아닌 상관계수는 향후 국내 다중편파 SAR 검·보정 계수 결정 및 SAR 다중편파 활용과정에서 오차로 작용할 수 있다는 점이 고려되어야 한다.

항만 진출입 컨테이너 트럭의 터미널 도착량 예측에 관한 연구: 신선대, 감만 터미널을 대상으로

김재헌,김진수,이건우 한국해양비즈니스학회 2019 해양비즈니스 Vol.- No.44

Truck arrivals at a container terminal with a purpose of importing or exporting containers influence on a work plan in the terminal, which includes a management of traffics and safety in a seaport, plans of importing or exporting containers in the terminal, and assigning workers and equipments which are required for importing or exporting containers. Therefore truck arrivals are factors which influence on an efficient management plan for the container terminal. This paper develops a model which predicts truck arrival volume at Sinseondae and Gamman terminal, where are parts of Busan port in Korea, using a dataset of ship arrival and departure from these two terminals, a dataset of container import or export in the container terminal belongs to these terminals, and a machine learning method. And then the developed model is compared to a linear regression model with mean squared errors of the predicted values. Comparing to a linear regression model, the developed model shows a less mean squared error value. It is expected that the outputs from the model can be used for a management plan of the container terminal, and the developed model can be applied to other container terminals in Korea through an additional data collection.

Is Tamsulosin 0.2 mg Effective and Safe as a First-Line Treatment Compared with Other Alpha Blockers?: A Meta-Analysis and a Moderator Focused Study

김재헌,심성률,장인호,신인수,황성동,김계환,윤상진,송윤섭 연세대학교의과대학 2016 Yonsei medical journal Vol.57 No.2

Purpose: Tamsulosin 0.2 mg is used widely in Asian people, but the low dose has been studied less than tamsulosin 0.4 mg orother alpha blockers of standard dose. This study investigated the efficacy and safety of tamsulosin 0.2 mg by a meta-analysis andmeta-regression. Materials and Methods: We conducted a meta-analysis of efficacy of tamsulosin 0.2 mg using International Prostate SymptomScore (IPSS), maximal urinary flow rate (Qmax), post-voided residual volume (PVR), and quality of life (QoL). Safety was analyzedusing adverse events. Relevant studies were searched using MEDLINE, EMBASE, and Cochrane library from January 1980to June 2013. Results: Ten studies were included with a total sample size of 1418 subjects [722 tamsulosin 0.2 mg group and 696 other alphablockers(terazosin, doxazosin, naftopidil, silodosin) group]. Study duration ranged from 4 to 24 weeks. The pooled overall standardizedmean differences (SMD) in the mean change of IPSS from baseline for the tamsulosin group versus the control groupwas 0.02 [95% confidence interval (CI); -0.20, 0.25]. The pooled overall SMD in the mean change of QoL from baseline for the tamsulosingroup versus the control group was 0.16 (95% CI; -0.16, 0.48). The regression analysis with the continuous variables (numberof patients, study duration) revealed no significance in all outcomes as IPSS, QoL, and Qmax. Conclusion: This study clarifies that tamsulosin 0.2 mg has similar efficacy and fewer adverse events compared with other alphablockersas an initial treatment strategy for men with lower urinary tract symptoms.

임목육종을 위한 조직배양

김재헌 한국식물생명공학회 ( 구 한국식물조직배양학회 ) 1985 식물조직배양과 산업적 이용 Vol.- No.-

단 한 개의 영리병원도 안 된다

김재헌 한국노동조합총연맹 2022 월간 한국노총 Vol.581 No.-

Streptomyces coelicolor A3(2)의 Acetyl Xylan Esterase를 발현하는 Escherichia coli의 과산화수소 저항성

김재헌,최원일,윤석원,정상운,오충훈,Kim Jae-heon,Choi Won-ill,Youn Seock-won,Jung Sang Oun,Oh Chung-Hun 한국미생물학회 2004 미생물학회지 Vol.40 No.3

Streptomyces coelicolor A3(2)의 acetyl xylan esterase (AxeA)가 Escherichia coli의 과산화수소 저항성에 미치는 영향을 알아보고자 하였다. AxeA 발현은 isopropyl-$\beta$-thiogalactoside로 유도되었고 생산된 AxeA는 SDS-polyacrylamide gel electrophoresis방법으로 확인하였다. AxeA 발현에 따른 과산화수소 저항성의 변화를 E. coli의 생장곡선과 생존율을 통하여 조사하였다. AxeA가 발현되지 않으면 모든 처리 농도 (1 mM, 2.5mM, 5mM)에서 균의 사멸이 일어났다. AxeA가 발현되는 조건에서는 5mM을 제외한 과산화수소 1mM와 2.5mM에서 E. coli의 사멸이 저지되었다. 또한 1.5mM의 과산화수소에 대한생존율이 59%에서 74%로 높다졌다. 동시에 E. coli의 최고생장온도에서에 근접한 $45^{\circ}C$에서의 생존율도 증가되는 결과를 얻었다. 그러므로 AxeA 단백질은 산화적 스트레스와 온도스트레스에 대해 교차 저항성을 나타내는 역할을 한다고 결론지었다. We investigated hydrogen peroxide resistance of Escherichia coli possessing acetyl xylan esterase(AxeA) of Streptomyces coelicolor A3(2). The induction of AxeA production by isopropyl-$\beta$-thiogalactoside was confirmed by SDS-polyacrylamide gel electrophoresis. The differences in growth between induced and non-induced E. coli were determined by the changes in optical density of cultures after hydrogen peroxide treatment The lethal effect of hydrogen peroxide was observed for non-induced cultures at all concentrations tested in this study (lmM, 2.5mM and 5mM). However, cultures induced for AxeA production resisted the lethal effect, except at 5mM where cells were killed irrespective of the AxeA production. The axeA induction increased survival against 1.5mM hydrogen peroxide from 59% to 74%. In addition, AxeA producing E. coli showed increased survival at $45^{\circ}C$, near maximum growth temperature. Therefore, it was concluded that AxeA conferred a cross-resistance upon the bacterium against both oxidative- and heat stress.

관형 연소기의 열-음향 진동에 의한 소음 특성 예측

김재헌,이정한,이수갑,정인석 한국음향학회 1999 韓國音響學會誌 Vol.18 No.7

일반 내연기관이나 산업용로, 로켓 엔진 등의 기본적인 형상이라고 할 수 있는 관형 연소기에서 발생하는 연소 소음은 열-음향 되먹임 현상에 의해 야기되는 형태가 지배적이며. 심할 경우 시스템의 파괴를 야기할 수도 있는 중요한 문제이다. 본 연구에서는 열-음향 진동중에서도 열-기인 음향 진동으로 분류될 수 있는 현상에 초점을 맞추어 유동장, 음향장 및 연소 반응을 수치적으로 해석하여 여러 주어진 조건에 따른 정상적인 해석뿐만 아니라 음압 수준이나 기본 주파수 예측과 같은 정량적인 결과 도출을 효과적으로 수행할 수 있는 수치적 기법의 개발을 목적으로 하였다. 다양한 당량비를 가진 혼합기에 대해 수치 해석을 수행한 결과 실험 측정치의 경향과 잘 일치할 뿐만 아니라 정량적인 면에서도 상당히 정확한 예측을 할 수 있음을 확인하였다. Thermoacoustic oscillation is a significant problem in cylindrical-type combustors such as common internal combustion engines, industrial furnaces, gas turbine, etc. This kind of low frequency oscillation can lead to serious consequences such as destruction of the combustor and production of strong noise. The accurate numerical simulation of thermoacoustic phenomena is a complex and challenging problem, especially when considering the chemical reaction of mixtures. As with other simulations of aerodynamics and aeroacoustics, the direct computation of thermoacoustic phenomena requires that Navier-Stokes equations be solved using accurate numerical differentiation and time-marching schemes, with non-reflecting boundary conditions. The numerical approach used here aims at qualitative analysis and efficient prediction of those problems, not at the development of an accurate scheme. The numerical prediction developed in this work is shown to be reasonably matched with experimental result.

GIS를 이용한 사방구조물 적지선정 시스템 개발

김재헌,윤호중,이창우 한국임학회 2004 한국임학회 학술발표논문집 Vol.2004 No.-