Seed of Trichosanthes kirilowii MAXIM Inhibits TNF-α-induced Migration in Human Aortic Smooth Muscle Cells Via MMP-9 Inhibition

김재은,최달영 한의병리학회 2009 동의생리병리학회지 Vol.23 No.2

Atherosclerosis, slow progressing inflammatory lesion in arteries, is one of the major causes of cardiovascular diseases. As mortality due to cardiovascular disease keeps increasing in Korea, researches on pathological mechanism of atherosclerosis may be beneficial in fighting against cardiovascular diseases. It is known that migration and MMP-9 secretion of Vascular Smooth Muscle Cell(VSMC) play a significant part in pathogenesis of atherosclerosis, although detailed mechanism of entire process is not clarified. We investigated whether the seeds of Trichosanthes kirilowii maxim (TS). inhibit migration and MMP-9 production of HASMC(human aortic SMC), which were induced by TNF-α treatment. Migration assay showed that TS inhibited the migration of HASMC induced by TNF-α, in dose dependent manner. Also by Zymography MMP-9 production of HASMC was found to be reduced by TS, both in time and in dose dependent manner. Western blotting results suggest TS suppress activity of MAPkinases.

청소년이 지각한 비공식 낙인과 부모 갈등이지위 비행과 부정 정서에 미치는 종단적 영향 연구

김재은,이동혁 한국청소년학회 2018 청소년학연구 Vol.25 No.12

The purpose of this research was to verify the longitudinal relationships between informal stigma, marital conflicts, and behavior problems of adolescents. 2,713 middle school 2nd graders participating in 2nd-5th year Korea Youth Panel Survey(KYPS) respondents were selected as the research subjects. The multivariate latent growth model was used as the research method to identify the mutual influences and longitudinal trajectories of the variables. The research results are as follows. There were aspects of linear transformation between informal stigma, marital conflicts, status delinquency, and negative emotions. Also, there was a statistical significance regarding both initial values and individual difference of development trajectories. Concerning the changes in each variable, first, few changes were found in informal stigma. Second, the marital conflicts decreased gradually. Third, the status delinquency increased for four years, and lastly, negative emotions decreased gradually. As a result of identifying the causal relationships between the variables, the initial value of informal stigma had a significant positive impact on the initial value of status delinquency, whereas it had no significant impact on the change rate of status delinquency. Also, the initial value of informal stigma had a significant positive impact on the initial value of negative emotion, while it had no significant impact on the change rate of negative emotion. The change rate of informal labeling had a significant positive impact on both status delinquency and negative emotion. Nonetheless, the initial value and change rate of marital conflicts had no significant impact on initial value and change rate of both status delinquency as well as negative emotion. 본 연구의 목적은 청소년이 지각한 비공식 낙인과 부모 갈등이 청소년의 지위 비행과 부정 정서에 어떠한 종단적 영향을 미치는지 분석하는 데 있다. 연구의 대상으로 한국 청소년패널조사(Korea Youth Panel Survey)에서 실시한 2-5차 연도 설문에 모두 응답한 중학교 2학년 패널 2,713명을 선정, 다변량 잠재성장 모형(multivariate latent growth model)을 활용하여 데이터를 분석하였다. 연구 결과, 비공식 낙인, 부모 갈등, 지위 비행, 부정 정서의 항목에서 선형의 변화 양상을 확인 할 수 있었고, 초기치와 발달 궤적의 개인차에서 통계적으로 유의하다는 결과가 도출되었다. 변인 간 인과관계 분석 결과에 따르면, 비공식 낙인의 초기치는 지위 비행의 변화율과 부정 정서의 변화율에는 유의한 영향을 미치지 않았으나, 지위 비행의 초기치, 그리고 부정 정서의 초기치에는 정의 영향을 미치는 것으로 나타났다. 비공식 낙인의 변화율은 지위 비행과 부정 정서에 통계상 유의미한 정의 영향을 준다. 하지만 부모 갈등 초기치와 부모 갈등 변화율의 경우, 지위 비행의 초기치, 변화율, 그리고 부정 정서의 초기치 및 변화율에 유의미한 영향을 미치지 않았다. 연구결과를 종합 해 볼 때, 정서적으로 어려움을 경험하고 있거나 지위 비행을 보이는 청소년들을 상담할 때, 이들이 비공식 낙인을 인식하고 있지 않은지 탐색해 볼 필요가 있음을 알 수 있다.

UAV 응용을 위한 저가형 압력 고도계 개발

김재은,유혁,안이기,권태용,조창호 한국항공우주학회 2003 한국항공우주학회 학술발표회 논문집 Vol.- No.-

내 삶의 역사와 함께한 책들

김재은,Kim, Jae-Eun 대한출판문화협회 1997 출판저널 Vol.209 No.-

Effects of corrective exercises on selective functional movement assessment and health risk appraisal in middle-aged women

김재은,김청,김신섭 물리치료재활과학회 2016 Physical therapy rehabilitation science Vol.5 No.4

Objective: The purpose of this study was to find the limited patterns of middle-aged women in selective functional movement evaluation and analyze the effects of pattern improvement exercises and general control groups on the Health Risk Appraisal (HRA). Design: Randomized controlled trial. Methods: The 31 subjects were physically healthy middle-aged women aged 40-59 living in Seoul, The subjects were randomly divided into an experimental group and a control group. Forty-three physically healthy women were originally recruited and randomly assigned to either the experimental group (n=22) or the control group (n=21). However, due to lack of participation, a total of seventeen subjects in the exercise group and fourteen subjects in the control group participated in the study. All subjects were tested using Selective Functional Movement Assessment (SFMA) and HRA for the baseline measurement and joined an exercise program of their group for one hour per session, twice a week for four weeks. The experimental group was provided with the corrective exercises and the control group was given the general fitness program. A follow-up test was conducted after eight weeks from the baseline measurement. Results: Both experimental and control group showed significant changes in SFMA and HRA scores (p<0.05). In the experimental group and control groups, the SFMA and HRA showed significant improvement from baseline to 4 weeks (p<0.05). Also, in the experimental group, the SFMA was significantly improved from baseline to 8 weeks (p<0.05). For the experimental group, there was a significant improvement in SFMA after 4 weeks compared to the control group (p<0.05). Conclusions: The corrective exercise in the experimental group had a positive effect on the SFMA score as well as the general squat exercise in the control group. The corrective exercise and general control group had the same positive effect on the HRA score.

반사방지 특성을 통일시킨 실리콘 질화막 간의 패시베이션 특성 비교

김재은,이경동,강윤묵,이해석,김동환,Kim, Jae Eun,Lee, Kyung Dong,Kang, Yoonmook,Lee, Hae-Seok,Kim, Donghwan 한국재료학회 2016 한국재료학회지 Vol.26 No.1

Silicon nitride ($SiN_x:H$) films made by plasma enhanced chemical vapor deposition (PECVD) are generally used as antireflection layers and passivation layers on solar cells. In this study, we investigated the properties of silicon nitride ($SiN_x:H$) films made by PECVD. The passivation properties of $SiN_x:H$ are focused on by making the antireflection properties identical. To make equivalent optical properties of silicon nitride films, the refractive index and thickness of the films are fixed at 2.0 and 90 nm, respectively. This limit makes it easier to evaluate silicon nitride film as a passivation layer in realistic application situations. Next, the effects of the mixture ratio of the process gases with silane ($SiH_4$) and ammonia ($NH_3$) on the passivation qualities of silicon nitride film are evaluated. The absorption coefficient of each film was evaluated by spectrometric ellipsometry, the minority carrier lifetimes were evaluated by quasi-steady-state photo-conductance (QSSPC) measurement. The optical properties were obtained using a UV-visible spectrophotometer. The interface properties were determined by capacitance-voltage (C-V) measurement and the film components were identified by Fourier transform infrared spectroscopy (FT-IR) and Rutherford backscattering spectroscopy detection (RBS) - elastic recoil detection (ERD). In hydrogen passivation, gas ratios of 1:1 and 1:3 show the best surface passivation property among the samples.

포스터발표 : 토양오염 복원 ; UV에 의한 놀이터 모래 중의 대장균 불활성화

김재은,조민,오병택,윤제용 대한상하수도학회 2004 공동춘계 학술발표회 논문집 Vol.2004 No.-

MATLAB으로 배워 보는 유전 알고리듬 (1)

김재은 한국소음진동공학회 2013 소음 진동 Vol.23 No.5

Cu_(1-x)Ag_xGaSe_2와 AgGaS_2의 Cathodoluminescence

김재은,박해용 全北大學校 1983 論文集 Vol.25 No.-

The temperature dependence of the cathodoluminescence spectra of Cu_(1-x)Ag_xGaSe_2 and AgGaS_2 was observed, and compared with the results obtained from the photoluminescence spectra of these crystals. Two kinds of spectra were found to be almost identical, except that the cathodoluminescence pecks were shifted a little toward high energy side compared with the photoluminescence peaks.

MATLAB으로 배워 보는 유전 알고리듬 (2)

김재은 한국소음진동공학회 2013 소음 진동 Vol.23 No.6