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Indications of an Adaptive Response to X-ray in Lymphocytes of Radiographers
김양지,송주영,최수영,정해원 한국유전학회 2007 Genes & Genomics Vol.29 No.4
Lymphocytes obtained from radiographers were iradiated with high-dose X-rays and analyzed for chromosome aberations and micronuclei to examine whether an adaptive response to ionizing radiation can be induced. The study subjects were seven male ome aberrations was lower in the lymphocytes of radiographers than in those of the controls when the lymphocytes were irradiated with 1 Gy of X-rays (7.93± 0.78 in radiographers, 8.31± 0.53 in controls), whereas the frequency was higher in the lymphocytes of radiographers before the irradiation (1.36±0.35 in radiographers, 0.13± 0.08 in controls). The same trend was observed for the frequency of micronuclei, but the diference was not statisticaly significant. The asociation with the frequencies of chromosome aberrations and micronuclei after 1 Gy of iradiation was significantly correlated in the radiographers and controls (Spearman’s correlation r=0.5, p=radiographers was correlated with the total cumulative dose (Spearman’s correlation, CA frequency, r=0.7, p<0.05; MN frequency, r=0.5, p=0.1). Thus, an adaptive response was observed in the radiographers, and therefore chronic occupational radiation exposure might act as an adapting dose.
김양지,윤갑근 한국문화공간건축학회 2021 한국문화공간건축학회논문집 Vol.- No.73
All human actions are done in space, and the impact of space on us cannot be ignored. These spaces are also given meaning and value through human experience and become factors that can be determined by human psychological standards. From the perspective that space is the main body of human beings and should be a comfortable environment, we would like to analyze the impact of the experience of regenerative cultural space, which has recently revived the place and historical nature of the past and preserves eco-friendly spatial resilience. Verifying the hypothesis of the study showed that both the independent variables sensory experience and Pine & Gilmore's experience had a definitive effect on psychological healing, while the escape, playful and aesthetic experiences of Pine & Gilmore had a definitive effect on psychological healing, but no educational experience. Looking at the results comprehensively, the experience of regenerative cultural spaces affects human psychological healing, and in particular, escape experiences that feel out of everyday life and other spaces affect psychological healing the most. This can be said to be a psychological immersion given by the uniqueness and freshness created by the fusion of the sphere and God in a regenerative cultural space that is not felt in a uniform and formal urban space. As a result of this study, the regenerative cultural space is important as a space where people can feel psychological recovery and emotional stability, and the physical aspect of the space is important, but emotional space design for human experience will be necessary.
김양지,송지현,윤갑근 한국문화공간건축학회 2016 한국문화공간건축학회논문집 Vol.- No.53
IIndustrialization to meet human needs brought about improvement in many aspects of life including economic development and convenience in our daily life. Yet indiscriminate development of new materials and other things we needed caused environmental pollution, and began to damage both human society and natural environment. The recent trend related to this situation is expressed in the design aimed at environment-friendly models such as eco design and green design. Eco-friendly design refers to a design based on the idea of harmonious coexistence of humankind and nature pursuing benefits for both. We find the tendency toward eco-friendly design in the field of interior architecture too. Eco-friendly design elements in interior design find their key area in the finishing materials that are used for work within a space. Based on the understanding of the importance of the finishing materials in interior architecture, the present study makes a theoretical examination of the concepts of eco-friendly design and eco-friendly materials. Then it analyzes and evaluates the types and characteristics of eco-friendly materials that are in circulation in recent years so that it can identify the strengths and some areas to improve of the finishing materials for interior architecture. It is expected that this study will serve as a momentum to explore approaches to the new eco-friendly finishing materials for interior architecture in further research.
김양지,김현규,이학성 한국식품과학회 2018 Food Science and Biotechnology Vol.27 No.6
Chrysanthemum zawadskii (CZ) is a perennial herb belonging to the Asteraceae family. CZ is used medicinally to treat inflammatory and uterine diseases in Asia. CZ was extracted with 50% ethanol and CZ extract (CZE; at 125, 250, and 500 mg/kg body weight) was administered orally every day for 5 or 6 weeks to investigate the anti-diabetic effects in streptozotocin (STZ)-induced rats and STZ ? high-fat diet (HFD)-fed mice. CZE significantly decreased fasting blood glucose levels in STZ- and STZ ? HFD-induced diabetic models. In addition, glucose tolerance and insulin tolerance were improved in the STZ ? HFD ? CZE group by increasing insulin levels and decreasing hemoglobin A1c (HbA1c) levels in serum. Furthermore, CZE supplements decreased components of the serum lipid profile such as triglyceride, total cholesterol, and low-density lipoprotein cholesterol levels. These results suggest that CZE may be a potential candidate for controlling hyperglycemia.
초임계 이산화탄소 추출로 얻은 도라지 종자유의 기능성 및 에멀젼 특성
김양지,임지영,김인호,김석중 한국응용과학기술학회 2019 한국응용과학기술학회지 Vol.36 No.1
In this study, functional and emulsifying properties of oil extracted by supercritical carbon dioxide from balloonflower(Platycodon grandiflorum A. DC) seeds were investigated. The oil was lower in total polyphenol(8 mg/100 g), but higher in α-tocopherol(14.15 mg/100 g), β -sitosterol(116 mg/100 g) and stigmasterol(8 mg/100 g) than seeds. Based on DPPH radical scavenging activ ity, the oil(IC 50 =1235.5 μg/mL) showed similar antioxidant activity to the seeds(IC 50 =1138.2 μg/mL). At 1%(w/w) lecithin, O/W emulsion with balloonflower seeds oil had turbidity, microscopic image, mean particle size and emulsion stability similar to emulsion with soybean oil, but had lower turbidity and emulsion stability and larger mean particle size than emulsion with perilla seeds oil. Its surface tension was similar to perilla oil emulsion. 본 연구에서는 초임계 이산화탄소를 사용해 도라지(balloonflower, Platycodon grandiflorum A. DC) 종자로부터 추출한 유지의 기능성과 에멀전 특성에 대해 조사하였다. 종자에 비해 도라지 종자 유는 총 polyphenol(8 mg/100 g)의 함량이 낮았으나 α-tocopherol(14.15 mg/ 100 g), β -sitosterol(116 mg/100 g) 및 stigmasterol(8 mg/100 g)의 함량은 높았다. DPPH 라디칼 소거능으로 분석한 종자유(IC 50 =1235.5 μg/mL)의 항산화능은 종자(IC 50 =1138.2 μg/mL)와 유사하였다. 1%(w/w) lecithin 농도에서 도라지 종자유를 사용해 제조한 에멀젼은 탁도, 지방구 입자 크기 및 형상, 유화안정 성에서 콩기름을 사용한 에멀젼과 유사하였으나 들기름 사용 에멀젼보다는 탁도 및 유화안정성이 낮았고 지방구 입자는 크게 나타났다. 도라지 종자유 에멀젼의 표면장력은 들기름 에멀젼과 유사하였다.