Phentermine 및 Phendimetrazine으로 유발된 정신병적 장애 및 양극성 장애 증례군 연구

김수영,김태석,김대진,채정호,이창욱,주수현,Kim, Soo Young,Kim, Tae-Suk,Kim, Dai-Jin,Chae, Jeong-Ho,Lee, Chang Uk,Joo, Soo Hyun 대한생물정신의학회 2022 생물정신의학 Vol.29 No.1

Objectives Recently, weight loss has emerged as a national concern in South Korea, and this has resulted in an increase in the frequency of use of central nervous system (CNS)-stimulating appetite suppressants. This study aimed to collect cases of psychotic disorders and bipolar disorders triggered by phentermine and phendimetrazine and explore the clinical features and courses. Methods In this retrospective study, we analyzed the electronic medical records of patients and selected eight patients who developed psychotic symptoms and manic symptoms for the first time after taking phentermine and phendimetrazine. All cases were reviewed, and their clinical features and course were summarized. Results All eight patients developed psychotic symptoms, and one had accompanying manic symptoms. The final diagnosis was appetite-suppressant-induced psychotic disorder in four patients, schizophrenia in three, and appetite-suppressant-induced bipolar disorder in one. In addition, three patients were diagnosed as having substance-use disorder. The key psychotic symptoms of these patients were hallucinations and paranoia. Conclusions These case findings suggest that phentermine and phendimetrazine can cause psychotic disorder, bipolar disorder, or substance use disorder and that medical professionals and the public should practice caution when prescribing and using these drugs.

드라이클리닝 근로자들의 유기용제 폭로와 자각증상

김수영,김정윤,이연경,이석구,이영수,조영채,이태용,이동배,Kim, Soo-Young,Kim, Jeong-Yun,Lee, Yeon-Kyeng,Lee, Sok-Goo,Lee, Young-Soo,Cho, Young-Chae,Lee, Tae-Young,Lee, Dong-Bae 대한예방의학회 1998 예방의학회지 Vol.31 No.4

To investigate the exposure levels of organic solvents and subjective symptoms of dry-cleaning workers, 77 male and 52 female dry-cleaning workers who had been worked in a small city of Chungnam province, and a large city, Taejon were selected for the study group. Air concentrations of organic solvents in the working environment were analyzed, and subjective symptoms of dry-cleaning workers were surveyed, from July to August 1996. The results obtained were as follows : 1. The concentrations of organic solvents in the working environment were within permissible TLV-TWA limits. 2. For the 13 symptom clusters, the most frequently complained symptom clusters were fatigue as 71.3%, and followed by depression and urinary disturbances as 53.5% and 51.9%. Other symptom clusters complained were below 50%. 3. Positive response rates of subjective symptoms were significantly higher in worker groups such as lived in a large city, female, higher education level, more frequently alcohol drinking, higher concentration of organic solvent in working environment, work in alone. 4. Workers who had used solvent B showed 2.3 point higher scores of subjective symptoms than those of solvent A. Of the subjective symptoms scores, amnesia and nervousness were higher in solvent B user group than solvent B user group. 5. As a result of factor analysis, 3 factors such as depression, urinary disturbance and neurologic disturbance were selected. 6. As a result of the logistic regression analysis, sex, the number of fellow workers, working time, region, job tenure, smoking, alcohol drinking, ventilating system, concentration of organic solvent in working environment and place of residence were selected for the related variables. For the conclusion, even though the concentrations of organic solvents in the working environments of dry-cleaning workers were within permissible limit of TLV-TWA, many dry-cleaning workers complained symptoms, such as fatigue, depression, urinary disturbances and so on. And the factors affecting to the symptoms of dry-cleaning workers were the number of fellow workers, work hours, region, job tenure, smoking and alcohol drinking.

조원경본 「김영철전(金英哲傳)」의 로컬리티 : 박재연본과의 비교로 본

김수영 ( Kim Soo-young ) 민족문학사학회·민족문학사연구소 2021 민족문학사연구 Vol.76 No.-

조원경본은 1762년 무렵에 필사된 「김영철전(金英哲傳)」의 한문본 이본이다. 조원경본은 긴 편폭의 연의소설 계열 현전 이본 중 ‘김영철 서사’의 효시인 김응원(金應元)의 「김영철유사(金英哲遺事)」에 시간적으로 가장 가깝다. 본고에서는 이처럼 선본(先本)에 해당되는 조원경본의 로컬리티를 후대의 다른 한문본 이본인 박재연본과의 비교를 통해 고찰했다. 조원경본과 박재연본은 모두 연의소설 계열의 이본으로서 서사의 경개가 대체로 유사하다. 이에 평안도 지역의 특수성과 그 하위주체의 비판적 문제제기가 공통적으로 보인다. 그렇기는 하지만 조원경본의 로컬리티가 박재연본보다 한층 더 뚜렷하고 예리하다. 첫째, 조원경본은 17세기 평안도 하층민 김영철이 겪은 고통이 국가의 공적 체제에서 기인하는 것임을 일관되게 비판적으로 말하고 있다. 이와 달리 후대의 박재연본은 김영철이 겪은 고통이 유림이라는 한 위정자의 사적 원한에서 기인하는 것으로 일부분을 개작해 놓았다. 둘째, 조원경본의 끝부분에는 하위주체로서 각성한 김영철 자신이 한양의 조정을 향해 스스로 목소리를 내어 자신의 고통을 말하고, 공적을 인정받게 해달라고 호소한 사건이 명확히 서술되어 있다. 이와 달리 박재연본은 이 부분이 다소 모호하게 서술되어 있다. 이처럼 박재연본에 비해 조원경본에 로컬리티가 현저하게 보이는 것은, 「김영철유사」에 담긴 로컬리티와 관련된 문제의식이 크게 퇴색되지 않은 채 조원경본으로 전승된 결과로 추정된다. Jowongyeongbon(Kimyoungcheoljeon owned by Jo Won-gyeong) is the text of the classical Chinese version of Kimyoungcheoljeon, which was copied around 1762. A relatively long version of the scripts that exist today, Jowongyeongbon is the closest in time to Kimyoungcheolyusa, the origin of Kim Young-cheol’s narrative. In this paper, the locality of Jowongyeong_ bon, which was written in this early period, was examined by comparing it with the other later classical Chinese version of Parkjaeyeonbon (Kimyoungcheoljeon owned by Park Jae-yeon). Both Jowongyeongbon and Parkjaeyeonbon are scripts of the Yeon-eui(演義) novel series, and the narratives in these two works are generally similar. The local specificity of Pyeongando and the critical problem raised by its subaltern have much in common. However, the locality of Jowongyeongbon is more distinct and sharper than that of Parkjaeyeonbon. The reason behind this difference is that Jowongyeongbon was passed without much fading of the awareness of the locality contained in Kim Eung-won’s Kimyoungcheolyusa.

비주 버팀목으로 흡수성 고정판을 이용한 비첨 성형술

김수영,이수향,황은아,최현곤,김순흠,신동혁,엄기일,Kim, Soo-Young,Lee, Soo-Hyang,Hwang, Eun-A,Choi, Hyun-Gon,Kim, Soon-Heum,Shin, Dong-Hyeok,Uhm, Ki-Il 대한성형외과학회 2010 Archives of Plastic Surgery Vol.37 No.3

Purpose: Most surgeons have used autogenous cartilage for columella strut graft. But the supply of autogenous cartilage is often limited. So, this study is to investigate the usefulness of biodegradable plate as columella strut material. Methods: We studied 19 patients who have secondary cleft nasal deformity. Patients were divided into two groups. Group A patients who were not closed their growth plate underwent columella strut graft only with biodegradable plate through endonasal approach. The biodegradable plate was inserted between nasal tip and anterior nasal spine. Group B patients were closed their growth plate. They had an operation for columella strut graft with biodegradable plate fixed with autogenous conchal cartilage. If nasal tip projection was insufficient, we performed additionally onlay graft on nasal tip with autogenous soft tissue or remnant cartilage. Results: As a result of mean 14 months follow-up, we achieved a good nasal tip projection, narrowing of interalar distance and symmetrical nostril shape. No specific complications were reported except 2 cases, which were the extrusion of biodegradable plate into the nasal cavity and Staphylococcus aureus infection. Conclusion: The columella strut graft using biodegradable plate is simple and effective method. Biodegradable plate can be a good substitute for columella strut in patients who can not use autogenous cartilages.

수출회화로서 기산 김준근(箕山 金俊根) 풍속화 연구

김수영,Kim, Soo-Young 한국미술이론학회 2009 미술이론과 현장 Vol.8 No.-

Kim, Jun-Geun(Gisan) was a late 19th century Chosen dynasty painter who created numerous genre paintings for West European clients in the newly opened treaty ports of Wonsan, Busan and Inchon. The treaty ports in the late 19th century Chosen represented of the crossroads the economy, values, and the institutions of the West European powers. In particular, the agriculture-based economy, Confucianism, and land-owner noble class started being eroded by a commerce-based economy, the values of Christianity, West European institution, and a new class of people who amassed wealth from commerce. As Kim, Jun-Geun's paintings were created for sale to West European clients, they exhibit characteristics that are distinct from the traditional genre paintings in terms of presentation style and the selection of the subject matters. The export genre painting originated in the 18th century around Guangdong, China. Broadly, there are two styles of genre paintings: the Guangzhou style and Ningbo style. Kim, Jun-Geun's paintings resemble the Ningbo style. The Ningbo style tends to highlight the main subjects, form an album of small paintings, and provide a simple treatment of the scenes without the background. Kim, Jun-Geun's paintings cover most aspects of life of common people of his time, ranging well beyond the subjects matters of the traditional genre paintings. His subject matters include the scenes of funeral, folk games, Buddhist and ancestor worship, prison and punishment, shaman custom, debauchees, government officials' formal trips, beggars and handicapped, etc. Many of the subjects are the neglected and the oppressed of the society. And he presents in detail the dress and its ornament that the subjects wear, and all the utensils and things around them. Besides, his subjects' faces are generally expressionless, and their postures are stiff; as such, the feeling of liveliness or movement is lacking. It may be the results of Kim, Jun-Geun's taking the other perspective, namely of his West European clients, rather than his own. The adoption of the other perspective may in turn be a product of the Social Darwinism and the new sense of values that accompanied the infusion of Christianity and West European institutions. Kim, Jun-Geun's portrayals of his subjects appear to reflect the attributes with which the West European Orientalists' of the period characterized the people of the Far East, namely, backwardness, barbarity, irrationality, violence, and mysticism.

Korean guidelines for postpolypectomy colonoscopic surveillance: 2022 revised edition

김수영,곽민섭,Soon Man Yoon,정윤호,Jong Wook Kim,Sun-Jin Boo,Eun Hye Oh,Seong Ran Jeon,Seung-Joo Nam,Seon-Young Park,Soo-Kyung Park,전성란,Dong Hoon Baek,Mi-Young Choi,Suyeon Park,Jeong-Sik Byeon,Hyung Kil Kim,Jo 대한소화기내시경학회 2022 Clinical Endoscopy Vol.55 No.6

Colonoscopic polypectomy is effective in decreasing the incidence and mortality of colorectal cancer (CRC). Premalignant polyps discoveredduring colonoscopy are associated with the risk of metachronous advanced neoplasia. Postpolypectomy surveillance is the most important meth-od for the management of advanced metachronous neoplasia. A more efficient and evidence-based guideline for postpolypectomy surveillance isrequired because of limited medical resources and concerns regarding colonoscopy complications. In these consensus guidelines, an analytic ap-proach was used to address all reliable evidence to interpret the predictors of CRC or advanced neoplasia during surveillance colonoscopy. Thekey recommendations state that the high-risk findings for metachronous CRC following polypectomy are as follows: (1) adenoma ≥10 mm in size;(2) 3 to 5 (or more) adenomas; (3) tubulovillous or villous adenoma; (4) adenoma containing high-grade dysplasia; (5) traditional serrated adeno-ma; (6) sessile serrated lesion (SSL) containing any grade of dysplasia; (7) serrated polyp of at least 10 mm in size; and (8) 3 to 5 (or more) SSLs. More studies are needed to fully comprehend the patients most likely to benefit from surveillance colonoscopy and the ideal surveillance intervalto prevent metachronous CRC.

유아의 창의성과 음악능력이 음악적 창의성에 미치는 영향

정나영(Jung Na Young),김수영(Kim Soo-Young) 한국육아지원학회 2010 육아지원연구 Vol.5 No.2

본 연구는 유아의 연령과 성별에 따른 창의성, 음악능력, 그리고 음악적 창의성의 차이를 살펴보고, 유아의 창의성과 음악능력이 유아의 음악적 창의성에 미치는 영향을 알아보는 것을 목적으로 하였다. 이를 위해 대구․경북에 위치한 유치원과 어린이집에 다니고 있는 만 4, 5세 유아 338명의 창의성, 음 악능력, 그리고 음악적 창의성을 측정하였으며, 자료 분석을 위해 MANOVA와 중다회귀분석을 실시하 였다. 연구 결과 첫째, 유아의 음악 능력은 연령에 따른 차이가 유의하게 나타났으나, 유아의 창의성과 음악적 창의성은 연령과 성별에 따른 차이가 유의하지 않게 나타났다. 둘째, 유아의 창의성은 유아의 음악적 창의성에 유의한 영향을 미치는 것으로 나타났으나, 유아의 음악능력은 유아의 음악적 창의성 에 유의한 영향을 미치지 않는 것으로 나타났다. The purpose of this study was to analyze the effects of children’s creativity and musical ability on children’s musical creativity. 338 children, aging 4~5 who enrolled at kindergarten and child care center in Daegu and Gyeongbuk province were selected for the research and analysis. Three different methods were used as a tool for the research. First, children’s creativity evaluation scales for the teacher developed by Rho Young-hee, Kim Kyung-chul and Kim Ho(2006) was used to measure the children’s creativity. Second, PMMA(Primary Measure of Music Audition) developed by Gordon(1986) which was translated to Korean by Shin In-suk(1994) was used to measure the children’s musical ability. Finally, MCSM(Measures of Creativity in Sound and Music) developed by Wang(1985) which was translated to Korean by Hue Sun-hee(1996) was used to measure children’s musical creativity. All collected datum were analyzed by MANOVA Process of SPSS /PC and Multiple Regression Analysis. Summaries of the research results are as follows. First, children’s creativity had no differences in age and gender excepting partial differences in children’s independence and against-norm. Second, children’s musical ability had significant differences in age but no differences in gender. Third, children’s musical creativity had no differences in age and gender. Fourth, children’s creativity effected significantly on the children’s musical fluency and musical imagination, but not on children’s musical originality. Finally, children’s musical ability didn’t effect on the children’s musical creativity.

주의력결핍 과잉행동장애 아동에서의 심박 변이도와 양육 스트레스

김수영,이문수,양재원,정인과,Kim, Soo-Young,Lee, Moon-Soo,Yang, Jae-Won,Jung, In-Kwa 한국정신신체의학회 2011 정신신체의학 Vol.19 No.2

연구목적: 본 연구의 목적은 소아 청소년 정신과 외래를 방문하는 주의력결핍 과잉행동장애(Attention-Deficit/Hyper-activity Disorder, ADHD) 아동의 주의력 결핍 정도와 심박 변이도(Heart Rate Variability, HRV)의 인자와의 관계를 비교하고 주의력 결핍 과잉행동의 검사 척도를 통한 증상의 정도와 부모 양육 스트레스 정도와의 연관성을 평가하고자 하였다. 방 법: 2007년 8월부터 2009년 7월까지 고려대학교 구로병원 정신건강의학과의 소아 클리닉을 방문하여 ADHD 진단을 받은 환자 중 이전에 약물 치료를 받은 기왕력이 없는 환자를 대상으로 하였다. ADHD 진단 및 평가에 주의력 장애 진단 시스템(ADHD diagnostic system, ADS)과 ADHD 평가 척도(ADHD rating scale, ARS)를 이용하였고, HRV 측정은 5분 동안 시행되는 것으로 평가하였다. 또한 부모의 양육 스트레스 정도를 측정하기 위하여 부모의 양육 스트레스 척도를 이용하였고 지능검사로는 한국판 아동용 웩슬러 지능검사가 이용되었다. Pearson 상관 분석을 통해 ARS 변수, ADS 변수와 HRV의 인자, 양육 스트레스 변수들 간의 상관관계에 대하여 알아보았다. 결 과: ADHD로 진단 받은 59명의 환자가 본 연구에 최종 참여하였다. HRV 인자 중 주파수 영역 분석법에서 저주파 스펙트럼은 ADS 변수 중 반응 시간 변산성(r=0.325, p<0.05)과 유의한 상관관계를 보였으나, 그 외 ADS 변수들과 ARS 변수들과는 유의한 상관 관계를 보이지 않았다. 부모 양육 스트레스에서는 ARS의 부주의 인자의 증상 정도가 심해질수록 부모-자녀의 역기능적 상호작용과 자녀의 기질과 관련된 척도가 유의하게 증가하였고 과활동성 인자의 증상 정도가 심해질수록 부모의 스트레스와 자녀의 기질과 관련된 척도가 유의하게 증가되었으며 그 외에는 유의한 차이를 보이지 않았다. 결 론: 본 연구에서는 ADHD 아동들에서의 임상적 변인과 HRV의 인자 사이에서 일부 연관성을 보여주었다. 따라서 차후 HRV가 임상적으로 ADHD 아동들에 있어서 치료를 받은 후 정신적 할당에 향상되었는지를 알아볼 수 있는 도구 중 하나가 될 가능성을 보여 주는 것이라 할 수 있겠고 이후 이에 따른 양육스트레스의 변화 또한 전향적인 연구가 필요할 것으로 생각된다. Objective:The aim of this study was to evaluate the relationship between sustained attention deficits in Attention-Deficit/Hyperactivity Disorder(ADHD) children and short-term Heart Rate Variability(HRV) parameters. In addition, we evaluate the relationship between The ADHD rating scale(ARS), the computerized ADHD diagnostic system(ADS) and Parenting stress index- short form(PSI-SF). Methods:This study was performed in the department of children and Adolescent psychiatry, Korea university Guro hospital from august 2008 to January 2009. We evaluated HRV parameters by short-term recordings of 5 minutes. K-ARS and ADS are used for screening and identifying ADHD children. Intelligence was measured using Korean educational Developmental Institute-wechsler Intelligence Scale for Children. The caregivers Complete Parenting Stress Index scale for evaluation parent stress. Results:The low frequency(LF) was significantly correlated with response variability of ADS. However, the other variables of ARS and ADS were not significantly correlated with LF. Hyperactivity subscale of ARS was significantly correlated with parental distress subscale and difficult child subscale of PSI-SF and inattention subscale of ARS was also significantly correlated with dysfunctional interaction and difficult child subscale of PSI-SF. Conclusion:The LF, 0.10-Hz component of HRV is known to measure effort allocation. This study shows that the LF component of HRV is significantly correlated with the response variability of ADS. This means that more severe symptoms of ADHD were correlated with the increase in the LF that means decreased effort allocation. These results also support the clinical usability of HRV in the assessment of ADHD. Furthermore, PSI-SF is correlated with hyperactivity and inattention variables of ARS.

상동지역 페그마타이트 및 관계 화성암의 전기적 분화 특징

김수영,문희수,Kim, Soo-Young,Moon, Hi-Soo 대한자원환경지질학회 1994 자원환경지질 Vol.27 No.5

The tourmalines distributed in the Sangdong area belong to the dravite-schorl series in terms of the cell dimensions and the chemical compositions. Geochemical characteristics of tourmalines indicate that Naedeogni granite and pegmatite appear to be derived from Li-poor and Fe-riched aplite rocks, but Nonggeori granite is derived from Ca-poor or Si-riched pelitic rocks. The Mg+Fe contents of tourmaline in Naedeogni granitoids are decreased from the granites to the pegmatites with the Fe contents increased while Mg contents decreased. It indicates the differentiation during the crystallization of tourmalines. These phenomena are coincided with the chemical variations from cores toward rims of the zonal tourmalines. Such a compositional variations in Nonggeori granite can not be observed.

키르키스스탄 촌아슈 지역 화강섬록암질암 및 사질원 퇴적암의 지화학적 특징

김수영,지세정,박성원,Kim, Soo-Young,Chi, Sei-Jung,Park, Sung-Won 대한자원환경지질학회 2011 자원환경지질 Vol.44 No.4

연구지역의 조구조 위치는 북부 천산지괴 남단의 이식쿨 미세지각 연변부 봉합선 북부에 위치한다. 지구조적으로는 카지흐 만곡조산대에 속한다. 암층은 알타이드 조산복합대 이전의 대륙지각이나 대륙호 및 화산호에 발달되는 고 지각 (Paleo- continent) 조각들과 지각 퇴적물의 부가복합체(Accretionary complex)등으로 구성되어 있다. 이들은 대부분 후기 원생대 및 고생대층으로 구성되어 있다. 중앙아시아 조산대의 마그마 활동은 고 생대 초부터 화강암류가 관입하기 시작하여 고기-테티스 해양(Paleo-Tethys ocean)의 소멸과 함께 시베리아 지괴 (Siberia- Kazakhstan 미세대륙)와 타림-북중국 지괴의 대륙 충돌기(期)인 후기 데본기에서 전기 석탄가까지의 기간 동안 가장 활발하게 진행되었다. 이 기간에 키르기즈스탄의 광화작용이 집중적으로 일어났는데 주로 조산운동과 관련된 금광화작용(Orogenic gold deposit)과 섭입작용과 관련된 반암 동광화작용 및 스카론 광화작용이다. 촌아슈에 분포하는 화강암류의 암석지화학 특징은 전술한 섭입작용과 관련된 도호(Island arc)나 화산호(Volcanic arc)의 화학적 특정을 갖는 영역에 해당한다. 이들은 대부분 과알루미나(per -aluminous) 내지 메타알루미나(metaluminous) 계열의 암체들로서 동시 혹은 후 충돌 마그마호에서 유래된 특정을 보이고 있다. 촌아슈 광구지역의 지질은 캠브리아기에서 오도뷔스기의 해양 분지에서 형성된 육성 화산퇴적물로 구성된 Sokolot suite, Ashuairyk suite 층과 석회석, 이질암 등으로 구성된 캠브리아기의 Turgenaksuu suite 및 오도뷔스기의 Tashtambektan suite로 형성되었다. Pangea 육괴와 Angarida 대륙 충돌 단계인 중기 고생대에는 내해(內海) 퇴적층인 석탄기의 투룩층군(Turuk Stratum)이 형성되었다. 사암과 이질암은 해양 도호(島弧)나 활동성 대륙 연변부 환경에서 퇴적된 층으로 분류된다. 이 지역의 동 광화대 모암이 되고 있는 관입암체로는 석영섬록암-몬조섬록암-섬록암과 토날라이트-화강섬록암 계열의 암석이 있다. 촌아슈 광구에는 주로 적철석으로 되어 있는 철산화대가 광범위하게 발달하고 있다. 이 철산화대는 타쉬탐백토르스크 섬록암 복합체와 상부 리피안기와 캠브리아기의 변성 및 퇴적암 층군의 NE와 NW의 공액구조나 산포상으로 분포한다. 동 광화작용은 철 광화작용 이후 섬록암의 카리 변질작용과 규화작용 및 탄산염화 작용을 수반하면서 전기 타쉬탐백토르스크 섬록암 복합체 및 상부 리피안기와 캠브리아기의 변성 및 퇴적암 층군에 망상 또는 산포상의 열수 세맥군으로 배태된다. Chon-Ashuu copper mining claim area is located, in terms of the geotectonic setting, in the northern part of the suture line which is bounded with the marginal part of Issik-kul micro-continent on the southern part of North Tien-Shan terrane. The geological blocks of Chon-Ashuu districts belong to the southern tip of Kazakhstan orocline. The rock formation of this area are composed of the continental crust or/and arc collage and the paleo-continental fragments-accretionary wedge complex of pre-Altaid orogenic materials. ASI(Alumina Saturation Index) of Paleozoic plutonic rocks in Chon-Ashuu area belong to the peraluminous and metaluminous rocks which were generated from fractional crystallization of Island and volcanic arc crusts in syn-post collisional plate. The geology of the ChonAshuu area consists of upper Proterozoic and Paleozoic rock formations. According to Harker variation diagrams for Chon-Ashuu arenaceous sedimentary rocks, the silty sandstone of Chon-Ashuu area showing the mineralogical immaturity were derived from Island arc or the marginal environments of active continent in Cambro-Carboniferous period. Numerous intrusive rocks of Chon-Ashuu area are distributed along north east trending tectonic structures and are bounded on four sides by the conjugate pattern. The most common type of the plutonic rocks are granodiorite and monzodiorite. According to the molecular normative An-Ab-Or composition (Barker, 1979), the plutonic rocks in Chon-Ashuu area are classified into tonalite - trondhjemite - granodiorite (TTG) series which are an aggregation of rocks which is the country rock of copper mineralization, that are formed by melting of hydrous mafic crust at high pressure.