생쥐의 자궁에서 밀착결합 유전자 Occludin의 발현

김다혜,계명찬 한국수정란이식학회 2004 한국수정란이식학회 학술대회 Vol.2004 No.1

2P-262 Photoregulated Reactive Oxygen Species (ROS) producible nanoparticles for targeted cancer therapy

김다혜,나건 한국공업화학회 2017 한국공업화학회 연구논문 초록집 Vol.2017 No.0

A Study on Hallyu Tourism Revitalization Model: Focusing on the Case of Jeju Island

김다혜,서용건 한국상품학회 2023 商品學硏究 Vol.41 No.4

The purpose of this study is to analyze the government and local government's support policies for Hallyu tourism, identify the current status of Hallyu tourism in Jeju-do, and propose measures to revitalize Hallyu in Jeju-do. In order to achieve this purpose, the concept of Hallyu and Hallyu tourism was organized and previous research was reviewed. In addition, the government and local governments' support policies related to Hallyu tourism were investigated. In addition, we looked at Hallyu tourist spots related to dramas and movies in Jeju-do before and after COVID-19. In addition, as a music-related Hallyu tourist destination, Nanta Hall and a course proposed as a Hallyu-themed tourist attraction course by the Korea Tourism Organization in 2023 were examined. From this, as a plan to revitalize the current Hallyu tourism industry in Jeju-do, firstly securing the sustainability of drama and movie filming locations, secondly pursuing experiential Hallyu tourism facilities and diversity of facilities, and finally developing Hallyu tourism products and securing active promotion channels. These research results are expected to provide policy and practical implications for revitalizing Hallyu tourism in Jeju-do in the future.

초등학교 학생의 인지발달수준에 따른 과학 성취도 분석

김다혜,강은주,박강은,백남권,박종호 한국초등과학교육학회 2019 한국초등과학교육학회 학술대회 Vol.77 No.-

초등학생 시기의 학생들은 구체적 조작기에서 마지막 단계인 형식적 조작기에 이르게 된다. 과학적 개념을 이해하기 위해서는 다양한 인지구조를 활용할 수 있어야 한다. 하지만 인지발달단계의 변화 속도에는 개인차가 있으며, 과학 교육과정에서 요구하는 과학적 개념, 탐구 기능의 인지 수준도 다양하다. 본 연구에서는 초등학생의 인지발달수준을 조사하고, 인지발달수준에 따른 과학 성취도를 분석하고자 하였다. G시에 위치한 초등학교 6학년 5개의 학급을 대상으로 하였으며, 인지발달수준을 측정하기 위해 축소본 GALT(Group Assessment of Logical Thinking) 검사지를 사용하였다. 과학 수업은 과학전담교사가 5개의 학급을 모두 수업하였으며, 과학 교과에서 영역별로 실시한 수행평가 결과를 통해 성취도를 조사하고, 학생들의 인지발달수준과 과학 성취도의 상관관계를 분석하였다. 이를 통해 과학 성취도의 향상을 위한 효과적인 방안으로서 인지발달 수준의 변화를 촉진하는 교수학습방법 개발에 대한 시사점을 도출할 수 있을 것이다.

In vitro study of Streptococcus mutans adhesion on composite resin coated with three surface sealants

김다혜,권태엽 대한치과보존학회 2017 Restorative Dentistry & Endodontics Vol.42 No.1

Objectives: Although the coating of surface sealants to dental composite resin may potentially reduce bacterial adhesion, there seems to be little information regarding this issue. This preliminary in vitro study investigated the adhesion of Streptococcus mutans (S. mutans) on the dental composite resins coated with three commercial surface sealants. Materials and Methods: Composite resin (Filtek Z250) discs (8 mm in diameter, 1 mm in thickness) were fabricated in a mold covered with a Mylar strip (control). In group PoGo, the surfaces were polished with PoGo. In groups PS, OG, and FP, the surfaces polished with PoGo were coated with the corresponding surface sealants (PermaSeal, PS; OptiGuard, OG; Fortify Plus, FP). The surfaces of the materials and S. mutans cells were characterized by various methods. S. mutans adhesion to the surfaces was quantitatively evaluated using flow cytometry (n = 9). Results: Group OG achieved the lowest water contact angle among all groups tested (p < 0.001). The cell surface of S. mutans tested showed hydrophobic characteristics. Group PoGo exhibited the greatest bacterial adhesion among all groups tested (p < 0.001). The sealantcoated groups showed statistically similar (groups PS and FP, p > 0.05) or significantly lower (group OG, p < 0.001) bacterial adhesion when compared with the control group. Conclusions: The application of the surface sealants significantly reduced S. mutans adhesion to the composite resin polished with the PoGo.

Thermo-responsive Injectable Hydrogel Incorporated Piroxicam for Sustained Drug Delivery

김다혜,이정주,나건 한국고분자학회 2017 한국고분자학회 학술대회 연구논문 초록집 Vol.42 No.2

국화 꽃색 변경을 위한 플라보노이드 대사공학

김다혜,박상규,박보라,이종렬,임선형 한국육종학회 2018 한국육종학회지 Vol.50 No.4

In ornamental crops, the color and shape of flowers are one of the important traits. Generally, flower colors are determined by accumulating pigments such as carotenoids, flavonoids, and betalains. Among them, flavonoids are responsible for broad ranges of colors. Chrysanthemums are one of the most popular ornamental crops in the world, and there have been many efforts to change their flower color. In chrysanthemum flowers, cyanidin-based anthocyanin confers pink or red color, whereas terpenoid-based carotenoids are mainly responsible for yellow and green colors. However, blue colored chrysanthemums do not occur in nature. To date, there have been attempts to obtain blue or violet-colored chrysanthemum flowers through the introduction of a novel gene for accumulating delphinidin-based anthocyanins, while other studies have reported changing endogenous metabolites through the reconstruction of flavonoid biosynthesis. Since various transcription factors are involved in the regulation of flavonoid biosynthesis, it is important to understand not only the structural genes, but also the transcription factors required for the modification of flavonoid-based flower color. Therefore, in this paper, we describe the flavonoid biosynthetic pathway and its regulation, and review previous studies on the change in flower color through modification of flavonoid biosynthesis. This effort could be an important milestone in successfully achieving the modification of chrysanthemum flower color by means of plant biotechnology.

자폐성 장애 자녀를 둔 양육자의 인식 및 특성 분석: 소셜미디어 웹 크롤링과 텍스트 마이닝을 활용하여

김다혜,최은실 한국자폐학회 2023 자폐성 장애연구 Vol.23 No.3

본 연구는 국내 자폐성 장애 자녀를 둔 양육자의 인식 및 특성을 분석하고자 소셜미디어를 웹 크롤링 후 텍스트 마이닝을 진행하였다. 2020년 1월부터 2023년 6월까지 포털사이트 내 자폐성 장애 관련 운영 카페에서 1,526개의 글을 수집하였으며, 이를 통해 정보의 흐름에서 중심이 되는 내용을 확인하고자 하였다. 그 결과 빈도 분석에서 ‘말’, ‘ㅠㅠ’, ‘언어’, ‘치료’, ‘검사’가 높은 빈도수를 나타냈다. 둘째로 의미연결망 분석 과정 중 의미 중심성에서는 ‘엄마’, ‘생각’, ‘못하’가 높은 수치를 보였으며, 근접 중심성에서는 ‘못하’, ‘선생님’, ‘아이들’이 그리고 매개 중심성에서는 ‘못하’, ‘문제’, ‘시작’이 상위 연결성을 보였다. 마지막으로 CONCOR 분석 결과 가정 관련, 진단 관련, 개입 관련, 인식 관련 총 4개의 군집으로 분류되었다. 위 연구 결과를 바탕으로 본 연구의 의의 및 제한점을 논의하였다. This study aimed to analyze the social perceptions of linked autism disabilities and characteristics of parents of young children with autism disabilities in South Korea by web crawling social media and performing text mining. From January 2020 to June 2023, a total of 1,526 posts were collected from social media platforms, and examined to identify the main topics that directed the flow of information. The results were as follows. In the first frequency analysis, “speech,” “ㅠㅠ,” “language,” “treatment,” and “test” had the highest frequency. In network analysis, “mother,” “thinking” and “be bad” showed high connectivity in semantic centrality, and “be bad,” “teacher,” and “children” in mediating centrality. The CONCOR analysis was classified into a total of four clusters related to families, diagnosis, intervention, and perception. Based on the above research results, the implications and limitations of the study were discussed.

서울 망리단길 장소성의 인과구조 실증연구

김다혜,양승우 한국도시설계학회 2020 도시설계 : 한국도시설계학회지 Vol.21 No.5

This study aims to analyze the causality structure of the placeness of Mangridan-gil where substantial volume of relevant information have been shared on SNS. To this end, we conducted a user survey and analyzed and interpreted the causal structure of Mangridan-gil placeness using structural equation model and text mining. The results showed that: The “Activity” and “Physical environments” interacted with each other and affect the meaning of the place, and the meaning of the place affected the place-attachment and the formation of willingness to revisit. It was also found that “Activity” and “individual store” had significant effects on “popular image” and “urban street” on “familiar image”. Through the text mining analysis, we found that users were attracted by the landscape of Mangridan-gil where unique stores coexist in old alleys. This study has academic contribution in that it empirically analyzed the placeness of the commercial alley directly through user surveys, which had been examined only through indirect methods such as Internet data analysis in previous studies. 본 연구는 SNS상에서 정보공유가 활발히 이루어진 망리단길을 대상으로 많은 사람들이 골목상권을 방문하는 이유를 분석하고자했다. 이를 위해 본 연구는 이용자 설문을 실시하고 구조방정식모형을 이용해 장소성 인과구조를 분석했으며, 텍스트 마이닝을 이용하여 인과구조를 해석했다. 연구결과 망리단길의 ‘행위’와 ‘물리적 환경’은 서로 상호작용 하면서 장소 이미지에 유의한 영향을 미치고, 장소 이미지는 장소애착과 재방문의사 형성에 유의한 영향을 미치는 것으로 나타났다. 이때 ‘행위’와 ‘개별점포’는 유행하는 이미지에, ‘가로공간’은 익숙한 이미지에유의한 영향을 미치는 것으로 나타났다. 또한 텍스트 마이닝 분석을 통해 이용자들이 오래된 골목길에 개성적인 상점이 공존하고 있는 망리단길의 모습을 매력적으로 느낀다는 것을 알 수 있었다. 본 연구는 새롭게 부상하는 골목상권을 대상으로 이용자 설문을 통해 장소성 인과구조를실증적으로 분석했다는 점에서 의의가 있다.

어머니의 정서인식 명확성이 유아의 문제행동에 미치는 영향 : 우울을 매개로

김다혜,최은실 한국아동심리치료학회 2017 한국아동심리치료학회지 Vol.12 No.2

The purpose of this study was to examine the relationship between mother’s emotional clarity and child’s problematic behavior by using the structure equation model. Mother’s depression was used as a mediating effect. Emotional clarity demonstrates how much an individual is being clear about their own mood and emotion. It surveyed 383 mothers with children aged between two and five who attended daycare and kindergarten in Gyeonggi province. As the measurement tools, it used the Trait Meta Mood Scale, the center for Epidemiological Studies-Depression and K-CBCL 1.5-5. Hypothetical models were suggested for the possible paths and roles between mother’s emotional clarity, mother’s depression and child’s problematic behavior based on previous literature. The results are as follows: First, it showed a negative correlation between these variables: the mother’s emotional clarity, the mother’s depression and the child’s problematic behavior. However, it showed a significant positive correlation between mother’s depression and child’s problematic behavior. Second, Mother’s depression acts as a complete mediation between mother’s emotion clarity and child’s problematic behavior. Based on these results, we discuss the significance as well as the restrictions of this study and make suggestions on directions for future research.