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유비쿼터스 정보화사업 평가모형 및 지표 개발에 관한 연구
김기호,김재전,이상준,Kim, Ki-Ho,Kim, Jae-Jon,Lee, Sang-Joon 한국디지털정책학회 2008 디지털융복합연구 Vol.6 No.3
This research aims at developing and distributing models and indexes that can evaluate ubiquitous information projects in order to enhance the objectivity and validity of their evaluation. The research adopts a BSC(Balanced Score Card) concept with four views, economic, policy, social, and technical views. The research induces a model of pre-evaluation and a model of post-evaluation according to each view. In order to secure the validity of the models, they are revised and complemented by obtaining advice through interviews with five experts in related fields, and the validity and application possibility of the indexes are verified by surveying ten people working in those fields. Finally, investigating their weights according to the importance of each view and index, they are evaluated using an AHP (Analytic Hierarchy Process) method.
외배엽 기원 세포암에서의 Metallothionein 발현의 의의
김기호,이민수,조광열 ( Ki Ho Kim,Min Soo Lee,Gwang Yeol Joh ) 대한피부과학회 1997 大韓皮膚科學會誌 Vol.35 No.1
Background: Metallothioneins(MTs) are ubiquitous low molecular weight cytosolic proteins with high contents of cystein that xhibit a selective binding affinity for zinc, copper and other group II heavy metal ions. In additi~on to the sequestration function and detoxification action, MTs probably participate in the cellirlar protection against. ionizing radiation and alkylating agent cytotoxicity and in cellular pn:liferation. Qbject : The objective of this study was to evaIuate the expression of MTs and to clarify t.heir role in carcinogenesis and/or biological behaviour in the neoplasms of ectoderrnal origin. Methods : We performed immunohistochemical studies on the surgical specimens of rnalignant rnelanoma and squamous cell carcinoma and basal cell carcinoma. The results were compared with the normal skin and mu osa and hair t,issues and raf't-on culture tissues of skin and mucosal keratinocytes. Results . 1) MTs were strongly expressed in epidermal basal cells of the normal skin and raft-on cultured artificial skin They were also rnore weakly expressed in epithelial basal cells of the normal mucosa and raft on cultured artificial mucosa and in matrix cells of the normal hair. 2) In rnalignant melanoma, MTs were meaningfully expressed, i.e., a strong expression was seen in the lesions showing a rapid vertical growth phase with fatal out,comes, but a weak expression in the cases whose precursor lesions were thought as dysplastic nevi, compared to the negative finding of norrnal melanocyt,es. The strong expression in a case of congenit.al rnelanocyt.ic nevus is considered as the activation of nevoid melanocytes. 3) MTs were weakly expressed in squarnous cell carcinoma with a diffuse aattern within the tumor mass. St,rong expression of MTs was particularly apparent in the poorl. differentiated squamous cell carcinoma and at the growing border of well differentiated squamous cell carcinoma. 4) In basal cell carcinoma, MTs were rather weakly expressed in solid cireumscribed types with a diffuse pattern and in cystic type with a patchy pattern. However they were not expressed in the solid infiltrative type. Conclusion : From these resuilts, we concluded that MTs were ubiquitously present in possible stem cells of various epithelial tissues except melanocytes irrespective of normal or artificial skin and/or mucosa including norrnal hair tissues. In the neoplasms of ectodermal origin, MTs might be involved in the invasive growth of tumor cells in the malignant melanoma and squamous cell carcinoma. It was implied that the role of MTs in basal cell carcinoma might be related to early events of hasal cell carcinogeresis and its down regulating tendency could be possible in its infil trative stage. (Kor J Dermatol 1997;35(1): 107-113)
염욕을 이용한 액상금속반응에 의한 Mg-Sb , Mg-Bi , Al-Sb 계 금속간화합물의 제조
김기호,윤우영 ( Ki Ho Kim,Woo Young Yoon ) 한국주조공학회 1994 한국주조공학회지 Vol.14 No.2
N/A The syntheses of intermetallic compounds through liquids reactions between two components are studied. Two different behavious to form the intermetallic compounds in the reaction are observed. One is a catastropic reaction which leads to a-rapid formation of intermetallic compounds and the other is a non-catastropic reaction which results to slow formation. The Mg-Bi and Mg-Sb system were selected to monitor the catastropic reaction and the Al-Sb system was chosen for the non-catastropic reaction. The reason of the reaction speed was rationalized by the heat evolution and the mixing enthalpies. Temperature for the Mg-Bi and Mg-Sb system was raised by about 250∼350℃ during intermetallic formations and the interface layer between the two liquids was planar and thick. But in the case of the Al-Sb system, temperature rise was only 4∼5℃ and many perforate and thin interfaces were observed. A new method to synthesize and separate the intermetallic compounds from the reacted liquids has also been developed. It is separated by density differences in a salt bath. The new method has been proved to attain the intermetallics without contamination from the base metals and can be applied not only to the Mg-Bi and Mg-Sb system which are catastropic reaction systems, but also the Al-Sb system which has slow reaction kinetics.
김기호,유황빈,Kim, Gi-Ho,Yu, Hwang-Bin 한국정보처리학회 2000 정보처리논문지 Vol.7 No.3
Representing 3-D objects with LOD requires a set of appropriate meshes according to the detail requirements. We have developed a system for improved geometry model data transmission and management by having only the wavelet coefficienets of the model corresponding to the detail levels, instead of generation all the meshes through wavelet transformation, when generating multiresolution meshes.