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만성신부전의 신경전도 검사에서 속도 , 진폭 및 잠복기간
김형규(Hyoung Kyu Kim),변관수(Kwan Soo Byun),권희규(Hee Kyu Kwon),노정우(Jung Woo Noh) 대한내과학회 1987 대한내과학회지 Vol.33 No.1
N/A With modern methods of treatment, overt clinical neuropathy of CRF is rare and a subclinical form is commoner in which only nerve conduction studies are abnormal. It should however be realized that for many such patients the conduction velocity would still be within the normal range, Furthermore, motor conduction velocity by itself gives an incomplete picture of the neurophysiologic abnormality. The amplitude and latency of peripheral nerve may reveal abnormalities when motor nerve conduction velocity values are within normal limits. The development of uremic neuropathy is related to decreasing renal function and accumulating uremic toxins. By the way, the authors examined the nerve conduction study such as velocity, amplitude and latency of the peripheral nerves of which 18 chronic renal failure have been treated only the supportive method. Serum BUN, Creatinine, Creatinine clearance, iPTH and vitamine B(12) which were examied with correlation of the resul1 taking from ulnar, radial, median, tibial and peronea nerves were investigated. The results obtained are as follows: 1) Frequency of abnormal nerve conduction involved to be in order the tibial 61.1%, peroneal 50% in motor nerves and tibial 44.4%, peroneal 42.9% and median 37.5% in sensery nerves. 2) The most frequent abnormalities are a decreased amplitude 55.8% in motor nerves and a delayed latency 40.5% in sensory nerves, 3) The mator nerve conduction velocities and latencies of CRF are delayed longer than those of normal controls significantly. 4) The motor nerve conducting tibial nerve has a negative correlation with serum vitamin-B(12) level significantly (r=-0,57, p<0.05). By the metioned results, we may suggest that not only velocity, amplitude and latency of motor nev , 4W also sensory nerves in upper and lower extrimities should be measured simultaneously in chronic renal failure probably complicated uremic neuropathy.
健康한 韓國人의 伏在神經, 천비골신경, 비복신경자극에 依한 Cerebral Somatosensory Evoked Potential에 關한 硏究
權希圭,吳貞姬 고려대학교 의과대학 1985 고려대 의대 잡지 Vol.22 No.3
A recording of cerebral somatosensory evoked potential(SEP) is possible by means of computer averaging by stimulation of peripheral sensory or mixed nerve. The cerebral SEP with the stimulation of the nerves of lower extremity is recorded at the Cz electroencepha ographic recording site in the midline of the scalp and a complex wave form is recorded with an initial positive peak(P₂) that is usually well defined and thought to represent the arrival of sensory impulses within the thalamocortical system. This study was conducted to measure the saphenous, superficial peroneal and sural nerves to determine the function of sensory component of L₄, L_(5), S₁ roots and conduction in spinal cord pathway to provide basic data for clinical use in diagnosis and management of that function. Fifty adult healthy Koreans, 34 males and 16 females ranging from 20 to 59 years(36.6±12.08) of age were studies, with the latency of evoked response(P₁, N₁, P₁, N₂), the amplitude of P₁-N₁, N₁-P₂, P₂-N₂ of each nerve were measured bilaterally. The results were summarized as follows: 1. A total of 100 saphenous nerve was stimulated and the mean values of SEP latencies (P₁, N₂, P₂, N₂) were 37.79±1.98 msec, 46.99±2.61 msec, 57.90±3.49 msec and 73.37±5.89 msec respectively and the mean values of SEP amplitudes(P₁-N₁, N₁-P₂, P₂-N₂) were 2.43±1.27 μV, 2.45±1.34 μV and 2.40±1.16 μV respectively. 2. A total of 100 superficial peroneal nerve was stimulated and the mean values of SEP latencies(P₂, N₁, P₂, N₂) were 38.72±1.55 msec, 47.71±2.52 msec, 58.66±3.14 msec and 73.65±4.85 msec respectively and the mean values of SEP amplitudes(P₁-N₁, N₁-P₂, P₂-N₂) were 2.82±0.98 μV, 2. 25±1.10 μV and 2.19±1.16 μV respectively. 3. A toral of 100 sural nerves was stimulated and the mean values of SEP latencies(P₁, N₁, P₂, N₂) were 38.27±2.04 msec, 47.03±2.77 msec, 58.50±3.79 msec and 73.8±4.80 msec respectively and the mean values of SEP amplitudes(P₁-N₁, N₁-P₂, P₂-N₂) were 2.34±1.04 μV, 2.47±1.05 μV and 2.22±0.91 μV respectively. 4. No statistical variation was noted with advancing age in latency and amplitude in SEP with each nerve stimulation. 5. There were no significant differences of latency and amplitude related to the dominance of extremities in SEP with each nerve stimulation. 6. There were no significant differences of latency and amplitude related to sex in SEP with each nerve stimulation. 7. No statistical variation was noted in increasing height in latency in SEP with each nerve stimulation.