The Effect of Disability on the Diagnosis and Treatment of Multiple Myeloma in Korea: A National Cohort Study

권지현,김소영,엽경은,한혜숙,이기형,신동욱,김연용,박종헌,박종혁 대한암학회 2020 Cancer Research and Treatment Vol.52 No.1

Purpose This study aimed to determine whether the diagnosis, treatment approach, and prognosis of multiple myeloma (MM) vary according to the presence and type of disability. Materials and Methods Demographic, socioeconomic, and medical data were obtained from the National Disability Database, the Korean Central Cancer Registry, and the Korean National Health Insurance claims database. An age- and sex-matched cohort was established using a 1:3 ratio constituted with 2,776,450 people with disabilities and 8,329,350 people without disabilities. Adult patients diagnosed with MM were subsequently selected from this cohort. Disabilities were categorized as physical, communication, intellectual or psychological, and affecting the major internal organs. Results The cohort included 4,090 patients with MM, with a significantly lower rate per 100,000 persons among people with disabilities than among people without disabilities (29.1 vs. 39.4, p < 0.001). People with disabilities were more likely to undergo dialysis treatment at the time of diagnosis (16.3% vs. 10.0%, p < 0.001), but were less likely to undergo autologous stem cell transplantation (37.5% vs. 43.7%, p=0.072). This trend was more evident among patients with intellectual or psychological disabilities. The median overall survival among patients with disabilities was significantly shorter than that among patients without disabilities (36.8 months vs. 51.2 months, p < 0.001). Conclusion In Korea, people with disabilities generally have a lower rate of MM diagnosis, receive less intensive treatment, and have a lower survival rate than people without disabilities.

게슈탈트 법칙을 활용한 패션 일러스트레이션 연구 - 폐쇄성의 법칙을 중심으로 -

권지현 한국일러스트레이션학회 2022 일러스트레이션 포럼 Vol.23 No.70

The purpose of this study was to analyze the cases of fashion illustration focusing on the law of closure, one of the Gestalt laws, which are the basic principles of visual perception, then to develop related fashion illustration works. Literature study, case study, and work study were tried as research methods and the results were as follows. First, case analysis showed that fashion illustrations using the law of closure induced the action of closure by treating a part of the foreground and background with the same color, and the foreground and background were perceived separately without physical contour expression. Second, as a work study, seven fashion illustrations using points, lines, and surfaces, which are basic elements of form, along with the law of closure, were presented. In order to activate the law of closure in each work, perception of the omitted outline was induced through 'use of patterns', 'overlapping', 'contrast of light and shadow', and 'implication through accessories' all of these being featured in the case study. In addition to the law of closure, other Gestalt laws such as similarity, proximity, common destiny, familiarity, and Prägnanz were also used for the perception of these works. The results of this study are meaningful in that it presents specific expression methods of using the law of closure in fashion illustration and are expected to be useful as references for systematic thinking and expression in the development of related works. 이 연구의 목적은 시지각의 기본원리인 게슈탈트 법칙 중 폐쇄성의 법칙을 중심으로 한 패션 일러스트레이션의 사례를 분석하고 관련 패션 일러스트레이션 작품을 개발하는 데 있다. 이를 위한 연구방법으로 문헌연구, 사례연구, 작품연구를 시도하였으며, 그 결과는 다음과 같다. 첫째, 사례분석 결과, 폐쇄성의 법칙을 활용한 패션 일러스트레이션은 전경과 배경의 일부를 동색으로 처리하여 폐쇄성의 작용을 유도하고, 물리적 윤곽 표현 없이 전경과 배경이 분리되어 지각되는 특성이 있음을 파악하였다. 둘째, 작품연구로서 폐쇄성의 법칙과 함께 형태의 기본 요소인 점, 선, 면을 활용한 7점의 패션 일러스트레이션을 제시하였다. 각 작품에서 폐쇄성의 법칙을 활성화하기 위해 사례연구에서 나타난 '패턴의 활용', '중첩', '명암대비', '장신구를 통한 암시' 등을 통해 생략된 윤곽의 지각을 유도하는 기법을 사용하였다. 또한 이 작품들의 지각을 위해 폐쇄성의 법칙 외에도 근접성, 유사성, 공통 운명, 친숙성, 프래그난츠와 같은 다른 게슈탈트 법칙도 활용하였다. 이 연구의 결과는 패션 일러스트레이션에서 폐쇄성의 법칙을 활용하는 구체적인 표현 방법을 제시한다는 점에서 의의가 있으며, 관련 작품의 개발을 위한 체계적인 사고와 표현의 참고자료로 활용될 것으로 기대한다.

일본의 산학관 공동연구와 특허전략

권지현 한남대학교 과학기술법연구원 2020 과학기술법연구 Vol.26 No.3

The Japanese government adds the creation of innovation in the industry- academic cooperation to the previous to "Framework Act on Science and Technology" in 2020 to revise to "Framework Act on Science and Technology Innovation", and for creating the innovation, also revises "Act on the Revitalization of Science and Technology Innovation". For positively promoting the common study and the industry-academic cooperation in universities and businesses by such a law, the guideline has announced and enforced. Like this the Japanese government positively promotes the common study of the industry-academic cooperation to correspond the rapid development of the innovation and science technology such as Al or loT etc. Further by entering into the employment contract between universities and businesses respectively, the concurrent office system in that all of both works can do has been enforced. As known through the current status of the technology transfer of universities and businesses in Japan, the Japanese universities receive the fellow from the businesses to co-study the technology substantially necessary to the business, and such a phenomenon implies to realize the industry-academic cooperation for achieving the purpose of deducing and solving a specific task by grafting the excellent specialist in the university and the industry-academic experience in the business. Although there is the previous law system, the Japanese government positively promotes various industry-academic cooperations of universities and businesses and industrializations of the results in 2020, and such a guideline and law system in Japan will be deeply analyzed and it is needed to refer the proper system in the development way of the industry-academic cooperation in Korea. 일본정부는 2020년에 들어와서 종전의 “과학기술기본법”에 이노베이션 창출을 추가하여 “과학기술·이노베이션 기본법”으로 변경․개정하고, 이와 더불어 “과학기술·이노베이션창출의 활성화에 관한 법률”에 이노베이션 창출을 위한 다양한 규정들을 반영하였다. 이러한 법률 개정들을 바탕으로 대학과 기업의 산학협력이 적극적으로 추진하기 위한 가이드라인을 새롭게 발표하여 시행하고 있다. 이와 같이 일본정부는 AI나 IoT 등 과학기술 및 이노베이션의 급격한 발전에 따라, 인문과학을 포함한 과학기술과 이노베이션 창출의 진흥을 일체적으로 도모하기 위한 산학협력과 공동연구를 추진하고 있다. 또한 산학협력과 공동연구를 적극적으로 추진하기 위하여 복수의 대학 또는 기업 간에 각각의 고용계약을 체결하여 양자의 업무를 모두 할 수 있도록 하는 겸직제도를 시행하고 있다. 특히 일본 대학과 기업의 기술이전 현황을 통해서 알 수 있듯이, 일본대학들은 기업으로부터 받은 전체연구 중 대부분이 대학과 기업이 공동연구계약을 하여 기업에 실질적으로 필요한 기술을 개발하고 있음을 알 수 있다. 이러한 현상은 대학의 우수한 전문 인력과 기업의 산학경험기술을 접목하여, 특정과제의 해결과 도출이라는 목적 달성을 위한 산학협력이 이루어지고 있음을 시사하고 있다. 일본 정부가 종전의 법제도가 있음에도 불구하고, 2020년도에 들어와서 대학과 기업의 다양한 산학협력과 그 성과물의 사업화를 적극적으로 추진하고 있으므로, 이러한 일본의 법제도 및 가이드라인을 심도 있게 분석하여 타당성이 있는 제도는 우리나라의 산학협력의 발전방안에 참고할 필요성이 있다.

연장된 의약특허존속기간의 유효 한도(캡)규정 도입방안

권지현 전남대학교 법학연구소 2023 법학논총 Vol.43 No.3

The current patent law stipulates that the period required to obtain a drug product license under the Pharmaceutical Affairs Act is regarded as a period in which a drug patent holder could not carry out a drug patent invention for a business and the duration can be extended up to a maximum of five years. However, there is no regulation on the validity limit (cap) of the duration for the combined period the extended duration and the residual duration. As a result, regardless of the date on which the drug is licensed, the drug patent holder receives an extension of the duration of up to five years and controls the drug market with an exclusive status. Meanwhile, generic pharmaceutical companies do not have a cap on the validity of the extended duration, so entry into the market of generic (or biosimilar) drugs may be restricted for a long time. There is a problem that the market supply of cheap generic drugs is delayed, which rather hinders the promotion of national health. Under the current regulation that the duration can be extended for up to five years as a way to solve these problems, like the United States, the EU, and China, it is necessary to introduce a maximum valid limit (cap) regulation in the Patent Act that the combined period of “extended duration” and “residual duration” cannot exceed a certain period (e.g., 14 years). 현행 특허법에는 약사법에 따라 의약품의 품목허가를 받기 위하여 소요된 기간을 의약특허권자가 업으로 의약특허발명을 ‘실시할 수 없었던 기간’으로 보고, 최장 5년의 기간까지 존속기간연장을 받을 수 있다고 규정하고 있다. 그러나 ‘연장 존속기간’과 ‘잔존 존속기간’의 합산 기간에 대한 존속기간의 최대 유효 한도(캡)에 관한 규정은 없다. 이로 인하여 의약특허권자는 의약품의 품목허가를 받은 날과 관계없이 최장 5년까지 존속기간연장을 받아 독점적 지위를 가지고 의약시장을 지배하게 된다. 한편 제네릭제약사는 연장된 존속기간의 최대 유효 한도(캡) 규정이 없는 관계로 제네릭(또는 바이오시밀러)의약품의 시장진입이 장기간 제한될 수 있다. 이는 값싼 제네릭의약품의 시장공급이 늦어지게 되어 국민건강 증진을 오히려 저해하게 되는 문제점이 있다. 이러한 문제점을 해결하기 위한 방안으로는 최대 5년간 존속기간연장을 받을 수 있다는 현행 규정 하에서, 미국 및 EU, 중국과 같이 ‘연장 존속기간’과 ‘잔존 존속기간’의 합산 기간이 일정기간(예, 14년)을 초과할 수 없다는 존속기간의 최장 유효 한도(캡) 규정을 특허법에 도입할 필요가 있다.

전도사를 활용한 발열 니트의 제조 및 발열특성에 관한 연구

권지현,임대영,Kwon, Jihyun,Lim, Daeyoung 한국섬유공학회 2022 한국섬유공학회지 Vol.59 No.5

In this study, the heating and electrode parts were knitted in one step using the intarsia technique while knitting heated knitted fabrics based on conductive yarn. The parallel structure possesses eight-line heating and electrode parts on both sides, which were designed to be knitted only with conductive yarn. Eight types of knitted fabrics were prepared based on the knitting principle and density of the electrode part, and their electrical and heating properties were considered. There was no issue of disconnection in the process of repeated and long-term experiments. The resistance along the course and wale directions of the electrode part knitted with high-density miss stitch was the lowest. When 6 V was applied, the heating temperature of knitted fabrics was maintained up to 62.7 ℃. The heating temperature could be controlled according to the voltage. In addition, the miss-stitch-based electrode structure with high density exhibited a smaller deviation in temperature than other structures, considering the center of the eight heating lines at 64.7 ℃ and the edge line at 53.5 ℃. Moreover, the heating rate was increased, and the time to reach the normal temperature was decreased. The knitting principle of the electrode part of the heating knitted fabric designed in this study more significantly affected the temperature change than the knitting density.

박용래 시의 죽음의식 연구

권지현 문예운동사 2018 문예운동 Vol.- No.140

한국인에서 경두개 초음파검사의 혈류감지와 관련된 인자들

권지현,권순억,김재승,배희준,김종성 대한뇌졸중학회 2002 Journal of stroke Vol.4 No.2

Background : Although transcranial doppler sonography (TCD) is a useful technique evaluating cerebral blood flow velocity, temporal acoustic window failure (TWF) limits its wide application in stroke patients. However, factors related to TWF remain unknown. The purpose of this study was to investigate the factors effecting TWF. Methods : We performed TCD in 104 consecutive patients (62 males and 42 females, aged 38 - 84 years) with ischemic stroke. We assessed the bone mineral density (g/cm2) of the L2, femur and the skull using bone mineral densitometry and measured the thickness of temporal bone shown in the CT scan with the use of PACS system. Results : Blood flow signals were recorded in 136(65.4%) of the 208 middle cerebral arteries. TWF was more common in women than men - 59.5%(50/84) vs. 17.7%(22/124) (p<0.001). Patients with TWF was significantly older than those without - 70.2¡¾8.4 years vs. 63.1¡¾7.2 years in women(p<0.005) and 67.4¡¾10.7 years vs. 60.9 ¡¾8.5years in men(p<0.001). TWF was not related with bone mineral density after adjusting the age and sex. However, the thickness of temporal bone was significantly greater in patients with TWF (3.3¡¾0.7 mm) than those without (2.3¡¾0.4 mm) (p<0.001). Besides, temporal bone was thicker in women than in men - 3.0¡¾0.8 mm vs. 2.4¡¾0.6 mm (p<0.001). Inhomogeneity in temporal bone was more common in patients with TWF than those without - 89.1% (41/46) vs. 15.4%(4/26) in women and 68.2%(15/22) vs. 18.6%(19/102) in men (p<0.001, each). Conclusions : TWF in Korean patients is related with advanced age, female sex and temporal bone thickness and inhomogeneity, but not with the mineral density of the temporal bone.

사례분석을 통한 현대한옥계획의 방향성에 관한 연구

권지현,우동주 대한건축학회지회연합회 2011 대한건축학회지회연합회 학술발표대회논문집 Vol.2011 No.1

금속 레이저 컷팅 기법을 활용한 패션 일러스트레이션 개발 - 페티시 패션 아이템의 표현을 중심으로 -

권지현 한국일러스트레이션학회 2023 일러스트레이션 포럼 Vol.24 No.74

패션 공유 플랫폼의 성공 요인과 국내 성장 방안

권지현 한국패션디자인학회 2018 한국패션디자인학회지 Vol.18 No.3

전 세계적으로 공유경제 시장이 급속하게 성장하고 있지만, 국내 패션 공유 플랫폼은 초기 단계에서 어려움을 겪고 있다. 이에 이 연구는 공유경제가 활성화된 미국의 성공 사례를 토대로 패션 공유 플랫폼의 성공 요인을 분석하고 국내 패션 공유 플랫폼의 성장 방안을 제안하고자 한다. 연구 방법으로 문헌 연구와 사례 연구를 실시하였으며 문헌 연구에서는 공유경제 및 공유 플랫폼의 특성을 고찰하였다. 성공 사례 연구는 여성 의류 중심의 영리 목적 패션 공유 플랫폼으로 범위를 한정하였다. 이 연구의 결과는 다음과 같다. 첫째, 패션 공유 플랫폼의 성공 사례에서 파악된 기본 유형은 ‘P2P 소유권 거래형’, ‘B2P 소유권 거래형’, ‘P2P 사용권 임대형’, ‘B2P 사용권 임대형’으로 나타났다. 또한 각 패션 공유 플랫폼의 연역, 투자 현황, 사업 규모, 인지도와 같은 운영 상태를 근거로 하여 포시마크, 스레드업, 스타일렌드, 렌트더런웨이가 각 유형의 대표적인 성공 사례로 분석되었다. 둘째, 패션 공유 플랫폼의 성공 요인은 ‘공유 자원의 가용성’, ‘신뢰성’, ‘기술성’, ‘접근성’, ‘사회적 연결성’, ‘경제성’, ‘협력성’으로 나타났다. 셋째, 패션 공유 플랫폼의 성공 요인과 국내 현황을 고려하여 수립된 한국 패션 공유 플랫폼의 성장 방안은 ‘공유 자원의 양적·질적 향상’, ‘신뢰성 확보’, ‘커뮤니티의 활성화’, ‘거래 채널 확대’, ‘기술성 강화’, ‘관련 주체 간 협력 체계 구축’, ‘비용 효율성 향상’, ‘공유 서비스 기반 구축’, ‘공유에 대한 인식 제고’로 요약된다. 이 연구의 결과는 초기 단계인 국내 패션 공유 플랫폼의 활성화를 위한 기초 자료로 활용될 수 있을 것이다. Although the market of sharing economy is growing rapidly all over the world, the Korean fashion sharing platforms are experiencing difficulties in its early stages. This study analyzes the success factors of the fashion sharing platform based on the successful cases of the US, where the sharing economy was activated. It also proposes a growth plan for the Korea fashion sharing platform. Literature studies and case studies were utilized. In literature review, characteristics of sharing economy and sharing platform were examined. Studies on successful cases have a limited scope, that is, they delved into for-profit fashion sharing platforms focusing on women’s apparel. The results of this study are as follows. First, the basic types identified in the successful cases of the fashion sharing platform include P2P ownership transaction, B2P ownership transaction, P2P usage rights rental, and B2P usage rights rental. In addition, Poshmark, ThreadUp, Style Rend, and Rent the Runway were analyzed as highly successful cases of each type based on operating status, such as history, investment status, business size, and awareness of each fashion sharing platform. Second, the success factors of the fashion sharing platform include availability of sharing resources, reliability, technological capability, accessibility, social connectivity, economic feasibility, and cooperativity. Third, considering the success factors and Korea's current situation, the study proposed a growth plan for Korean fashion sharing platform which includes the following: improving the quantity and quality of sharing resources, ensuring reliability, activating the community, expanding trading channels, building cooperative systems between related parties, improving cost-effectiveness, constructing infrastructures for sharing service, and raising awareness of sharing. The results of this study can be used as basic data to activate the Korean fashion sharing platform in its early stage.